Gene 82048.m00056 (T.vaginalis)
82048.m00056
Species: T.vaginalis
Alias: 82048.m00056, TvagK0830
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 82048.m00056.AA | Protein | None | 774 | None | Fasta, JSON |
| 82048.m00056.kin_dom | Protein Kinase Domain | None | 252 | None | Fasta, JSON |
Protein domains of 82048.m00056.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 82048.m00056.AA | SCY1 | 29-280 | 16 | 1.5e-31 | 106.52 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 29-280
Range on HMM: 1-337/337
Sequence Identity: 16% (57 aa)
WKVHSAVNKTTHDRVSLWLIDQE-------KITAEIQDQAVRDKYLSGSLAGIQKLRKLRHPHLLKILEVQESTSS-LGFASEPISSSLQTLIGSLNGDD
||.|... |.| ..|.. | . .|....... . ...| .||||..|..... | .. . .|.|.|...| .. . . .
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLK--------KQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKK
A------------------------------SYIC---FQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFN---------FDWSVPINGTKDINL
...| ||. ||..|||| ..|.|..|.||.||...| . |.. .| ..| . . ..
SCQTQKTQDVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMP
PFTQYFT------------------EITYPPLPYSSPEVVQC-------------RQSTCLADVFSFALVFYECISGKPLLLCKDKRE--------YDIG
.| .... .|.. .. ||.. . |. .|.||. .. .....|| .. .. . . .
WFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWN
RNPILSISGIGTNYMNL----FRGCLNIDASTRPDFTNILESEAF
. . . . | .. .. . |. |. |||. ..|... |
AMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
|
|||||||||
| S_TKc | 82048.m00056.AA | S_TKc | 17-280 | 18 | 5.2e-14 | 28.51 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 17-280 Range on HMM: 1-231/231 Sequence Identity: 18% (53 aa) YDNVNPIFTIGYWKVHSAVNKTTHDRVSLWLIDQEKITAEIQDQAVRDKYLSGSLAGIQKLRKLRHPHLLKILEVQESTSSLGFASEPISS---SLQTLI |. ...| .. ||. ...| |. .| . |. . || |.| .||.. |...| .. ..| . | .. .| ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI GS---------LNGDDASYICFQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFNFDWSVPINGTKDINLPFTQYFTEITYPPLPYSSPEVVQCRQ . .. .| ... |...|....|.. . | . || |.||| .|. | . . | . | | .|||. . KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTP-WYMAPEVL---G STC-LADVFSFALVFYECISGKPLLLCKDKREYDIGRNPILSISGIGTNYMNLFRGCLNIDASTRPDFTNILE-------SEAF .. .|. |. ..||...|.|. ... ... . .. |.||. | . || .|. . | YGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
| Kinase | 82048.m00056.AA | TKL | 124-278 | 14 | 6.6e-13 | 42.83 | In-house | 137-364 (364) | Show / Hide |
Range on Protein: 124-278 Range on HMM: 137-364/364 Sequence Identity: 14% (34 aa) ICFQLADAMQFLHNNAK-------MAHLGISPEAIFLDENLS--------------VKLFNFDWSVPINGTKDINLPF----------TQYFTEITYP-P .. . | .|..||.. ..| . .. |..|||. .|. | | ...... | .. | .| WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT LPYSSPEVVQ----------------CRQSTCLADVFSFALVFYECISGKPLLLCKDKR------------EYDI--GRNPILS-----------ISGIG . . .||| . ... . .||.||..|..|...... . . . .... |. | . . . PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCP TNYMNLFRGCLNIDASTRPDFTNILESE . . .| | . |.. || |. ||. PSMKKLMQDCWDHDPEKRPSFQEILKRL |
|||||||||
| Kinase | 82048.m00056.AA | TKL-Unique | 127-225 | 19 | 4.7e-09 | 28.25 | In-house | 118-225 (290) | Show / Hide |
Range on Protein: 127-225 Range on HMM: 118-225/290 Sequence Identity: 19% (22 aa) QLADAMQFLHNNAK-MAHLGISPEAIFLDEN-----LSVKLFNFDWSVPINGTKDINLPFTQY-----FTEITYPPLPYSSPEVVQC--RQSTCLADVFS . |..| .||.. . ..|. . . .. .|.| ...|. | . ... .|... ... |..... ...||| | .. .||.| DIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDF--GLSKFNSKINKMTNNEHKGTRNQTRCGSF--RWMAPEVLRMNFCQYSEKSDVYS FALVFYECISGK |. | .|....| FGIVLWEIATRK |
|||||||||
| Kinase | 82048.m00056.AA | Ciliate-E2 | 77-280 | 15 | 7.9e-09 | 26.42 | In-house | 86-365 (365) | Show / Hide |
Range on Protein: 77-280 Range on HMM: 86-365/365 Sequence Identity: 15% (45 aa) LRKLRHPHLLKILEVQE--STSSLGFASEPISS-SLQTLIG--------------SLNGDDASYICFQLAD---------------AMQFLHNNAKMAHL |..| ||...|. |. . ..... . | .. .|. .| ... ..|| |... |...||.. . | LEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR GISPEAIFLDENLSVKLFNFDWS-----VPINGTK---DINLPFTQYFTEITYP----------------PLPYSSPEVVQCRQ---------STCLADV | || |.. .|. | | .|.|. ...| .. |..|. ..| .||... . . .|. DIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI FSFALVFYECISGKPLLLCKDKREYDIGRNPILSISGIG---------TNY----------MNLFRG----CLNIDASTRPD-FTNILESEAF .|. ..||...||| ... . .... ... ..|.. .|. | . |.. . ||. . | WSLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
|||||||||
| Kinase | 82048.m00056.AA | Ciliate-E6 | 124-164 | 34 | 3e-06 | 16.29 | In-house | 58-97 (154) | Show / Hide |
Range on Protein: 124-164 Range on HMM: 58-97/154 Sequence Identity: 34% (14 aa) ICFQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFNF .| ||. |.. || . . . |... ||||.|. .|. | FCCQLFHAVEYLHSK-NYVLQNITLKNIFLDKNMNIKICDF |
|||||||||
| Kinase | 82048.m00056.AA | HH498 | 196-225 | 32 | 8e-06 | 14.01 | In-house | 193-223 (284) | Show / Hide |
Range on Protein: 196-225 Range on HMM: 193-223/284 Sequence Identity: 32% (10 aa) SPEVVQ-CRQSTCLADVFSFALVFYECISGK .||| | . . .||||.|.. .| ... APEVFSQCQKYSIKVDVFSYAMCIWEMHTRE |
|||||||||
| Kinase | 82048.m00056.AA | CAMK | 77-164 | 17 | 1e-05 | 13.6 | In-house | 85-240 (425) | Show / Hide |
Range on Protein: 77-164 Range on HMM: 85-240/425 Sequence Identity: 17% (28 aa) LRK-------LRHPHLLKILEVQES-----------TSS---------LGFAS---EPISS-----SLQTLI------------------GSLNGDDASY ..| |.||...|..|| |. | | . . | .| | | | .. ..|.. MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARR ICFQLADAMQFLHNNAKMAHLGISPEAIFLDEN-----------------LSVKLFNF . |...|....|.. .|. . || | ||.| .|. | YFRQICSAVHYCHSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF |
|||||||||
| Kinase | 82048.m00056.AA | Ciliate-C1 | 127-156 | 43 | 1.7e-05 | 9.64 | In-house | 137-165 (328) | Show / Hide |
Range on Protein: 127-156 Range on HMM: 137-165/328 Sequence Identity: 43% (13 aa) QLADAMQFLHNNAKMAHLGISPEAIFLDEN || .. |..|.| .|. . || |.|||| QLINVIQYIHQNN-ICHRDLKPENILLDEN |
|||||||||
| Kinase | 82048.m00056.AA | Ciliate-E2-Unclassified | 121-161 | 24 | 4.1e-05 | 13.71 | In-house | 140-188 (352) | Show / Hide |
Range on Protein: 121-161 Range on HMM: 140-188/352 Sequence Identity: 24% (12 aa) AS-----YICFQLADAMQFLHNNAKMAHLGISPEAIFLDENL---SVKL |. ... |. .. ..|| . . | | || |..|.| .|. AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI |
|||||||||
| TyrKc | 82048.m00056.AA | TyrKc | 17-280 | 16 | 0.00052 | -157.79 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 17-280
Range on HMM: 1-280/280
Sequence Identity: 16% (50 aa)
YDNVNPIFTIGYWKVHSAVNKTTHDRVSLWLIDQEKITA---EIQDQAVRDKYLSGSLAGIQKLRKL--RHPHLLKILEVQEST-------SSLGFASEP
. . .|. .. | |. ... | . . .. ..|| .||...... | . | |
ITLGKKLGEGAFGEVYKGTWK---------------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY
IS-----SSLQTLIGSLNGDDASYICFQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFNFDWSVPINGT-KDINLPFTQYFTE----ITYPPLPY
. . |. . |. .| ..|.| |. |..|| . . | . . ..||. || | | | . ..| . . .||.
MPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPI
--SSPEVVQCRQSTCLADVFSFALVFYECISG----KPL-----LLCKDKREYDIGRNPILSISG--------IGTNYMNLFRGCLNIDASTRPDFTNIL
.||. . . | ||.|| . .| . | . .. .|| .. . .. . | . |.. || |..|
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-
ESEAF
| |
-HECF
|
|||||||||
| Kinase | 82048.m00056.AA | MLK | 196-225 | 27 | 0.001246 | 8.62 | In-house | 201-233 (291) | Show / Hide |
Range on Protein: 196-225 Range on HMM: 201-233/291 Sequence Identity: 27% (9 aa) SPEVV---QCRQSTCLADVFSFALVFYECISGK .||| .| . . .||.|...|..| .... APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE |
|||||||||
| Kinase | 82048.m00056.AA | Pkinase | 192-227 | 27 | 0.00512 | 11.75 | Pfam | 175-211 (293) | Show / Hide |
Range on Protein: 192-227 Range on HMM: 175-211/293 Sequence Identity: 27% (10 aa) LPYSSPEVVQ-CRQSTCLADVFSFALVFYECISGKPL ..| .|||.. .. . .|..|. ...|| ..|.|. PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP |
|||||||||
| Kinase | 82048.m00056.AA | MLK | 260-278 | 36 | 0.062196 | 2.65 | In-house | 273-291 (291) | Show / Hide |
Range on Protein: 260-278 Range on HMM: 273-291/291 Sequence Identity: 36% (7 aa) CLNIDASTRPDFTNILESE | | |.. ||.| |.. CWNQDPHKRPSFRQIVQHL |
|||||||||
| Kinase | 82048.m00056.AA | MLK | 124-142 | 31 | 0.090937 | 2.07 | In-house | 129-147 (291) | Show / Hide |
Range on Protein: 124-142 Range on HMM: 129-147/291 Sequence Identity: 31% (6 aa) ICFQLADAMQFLHNNAKMA ...| | .|..||..|... WALQCARGMHYLHSMAPKP |
|||||||||
| Kinase | 82048.m00056.AA | Ciliate-E2-Unclassified | 255-280 | 26 | 0.148309 | 1.19 | In-house | 327-352 (352) | Show / Hide |
Range on Protein: 255-280 Range on HMM: 327-352/352 Sequence Identity: 26% (7 aa) NLFRGCLNIDASTRPDFTNILESEAF .|.. .|. . . |..| ||. | DLLQKMLKKNPNKRITFEQILNHPWF |
|||||||||
| Kinase | 82048.m00056.AA | TKL-Unique | 252-278 | 33 | 0.192572 | 1.07 | In-house | 264-290 (290) | Show / Hide |
Range on Protein: 252-278 Range on HMM: 264-290/290 Sequence Identity: 33% (9 aa) NYMNLFRGCLNIDASTRPDFTNILESE .| .| . | . | | || |..|... EYRDLIQQCWHHDPSQRPSFDEIIHRL |
|||||||||
| Kinase | 82048.m00056.AA | Pkinase | 77-138 | 12 | 3.314433 | 1.81 | Pfam | 54-127 (293) | Show / Hide |
Range on Protein: 77-138 Range on HMM: 54-127/293 Sequence Identity: 12% (9 aa) LRKLRHPHLLKILEVQESTSSLGFASEPISS-----SLQTLIG-----SL--NGDDASYICFQLADAMQFLHNN ...|.||. ...... |. ... . | .| ..| .. ... .. |.. .....|.. MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM |
|||||||||
| Kinase | 82048.m00056.AA | Pkinase | 258-280 | 34 | 3.537425 | 1.71 | Pfam | 271-293 (293) | Show / Hide |
Range on Protein: 258-280 Range on HMM: 271-293/293 Sequence Identity: 34% (8 aa) RGCLNIDASTRPDFTNILESEAF ..||. | . || .. ||... | KWCLCKDPKKRPTAEQILQHPWF |
|||||||||