TIF1g

Species: Mouse
Alias: Trim33, TIF1g
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: TIF1

Sequence

Name Sequence Type Origin Length Description Download
TIF1g.AA Protein Sugen 1140 None Fasta, JSON
TIF1g.NA RNA Sugen 8868 None Fasta, JSON

Protein domain

Protein domains of TIF1g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RING TIF1g.AA RING 139-198 21 1.2e-10 42.57 SMART 1-23 (23) Show / Hide
Range on Protein: 139-198
Range on HMM: 1-23/23
Sequence Identity: 21% (13 aa)

CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDVQQVGVIRCPVC
|..| .         |..||| | ||  |.                          ||.|
CPICLE---------PVVLPCGH-FCY-CI--------------------------CPIC

Zf-C3HC4 TIF1g.AA zf-C3HC4 139-168 25 0.001011 11.81 Pfam 1-33 (48) Show / Hide
Range on Protein: 139-168
Range on HMM: 1-33/48
Sequence Identity: 25% (9 aa)

CAVCQQSLQSRREAEPKLLPCLHS-----FCLRCL
|..|.. .    .  | ..||.|.     ||  |.
CWICHCEWKDPNN--PLIHPCGHRGSLKWFCHSCI

PHD TIF1g.AA PHD 138-199 18 0.039503 3.33 SMART 1-39 (39) Show / Hide
Range on Protein: 138-199
Range on HMM: 1-39/39
Sequence Identity: 18% (13 aa)

TCAVCQQSLQSRREAEPKLLPCL-------HSFCLRCLPEPERQLSVPIPGGSNGDVQQVGVIRCPVCR
.| ||..           .. |        |  ||.  .|                  . |  .|| ||
YC-VCGK---------G-MIQCDPGCDRWYHQ-CLGPPLE-----------------PPDG-WYCPRCR

BBOX TIF1g.AA BBOX 285-326 31 5.3e-13 50.44 SMART 1-51 (51) Show / Hide
Range on Protein: 285-326
Range on HMM: 1-51/51
Sequence Identity: 31% (16 aa)

QRPVFCPVHK-QEQLKLFC-ETCDRLTCRDCQLL-EH------KEHRYQFL
.||. |..|.  | ...|| |.|. . |.|| .  ||      . |....|
HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL

BBOX TIF1g.AA BBOX 226-273 25 4.7e-12 47.29 SMART 1-51 (51) Show / Hide
Range on Protein: 226-273
Range on HMM: 1-51/51
Sequence Identity: 25% (13 aa)

KSEQVCTSCEDNASAVGFC-VECGEWLCKTCIEA--HQRVKFTKDHLIRKK
.....|....... |. || ..|...||..| |.  ||..|....| ..  
HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL

Zf-B_box TIF1g.AA zf-B_box 286-326 28 2e-09 42.01 Pfam 1-45 (45) Show / Hide
Range on Protein: 286-326
Range on HMM: 1-45/45
Sequence Identity: 28% (13 aa)

RPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKE-----HRYQFL
..  || |..| |...|..|... |.|| . .||      |... .
QM-YCPEHPEEPLEYYCQDCQQCICEDCAVHGHKGNGFKKHTVVPI

Zf-B_box TIF1g.AA zf-B_box 227-273 16 8.9e-07 31.48 Pfam 1-45 (45) Show / Hide
Range on Protein: 227-273
Range on HMM: 1-45/45
Sequence Identity: 16% (8 aa)

SEQVCTSCEDNASAVGFCVECGEWLCKTCIEA-HQRVKFTKDHLIRKK
.. .|  ....  .  .| .|.. .|  |... |.. . .|.| ... 
QM-YCPEHPEEP-LEYYCQDCQQCICEDCAVHGHKGNG-FKKHTVVPI

RING TIF1g.AA RING 231-293 14 0.007892 6.68 SMART 1-23 (23) Show / Hide
Range on Protein: 231-293
Range on HMM: 1-23/23
Sequence Identity: 14% (9 aa)

CTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGTSGQRPVFCPVH
|. | .      .. .||   |. ||                                 ||. 
CPICLE-----PVVLPCGH-FCY-CI---------------------------------CPIC

PHD TIF1g.AA PHD 248-258 45 0.203927 6.02 Pfam 44-54 (54) Show / Hide
Range on Protein: 248-258
Range on HMM: 44-54/54
Sequence Identity: 45% (5 aa)

GEWLCKTCIEA
|||.|. |...
GEWYCPRCKCC

BBC TIF1g.AA BBC 333-459 32 4.7e-47 163.57 SMART 1-132 (132) Show / Hide
Range on Protein: 333-459
Range on HMM: 1-132/132
Sequence Identity: 32% (43 aa)

QKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVN-----ETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVM
.. ..| .|.|| .|... ..|. |.||.|..|.     |. ..|||.|......|.|..|...| .|..|.......|..| ||. ..|....|..|..
HREKLEQHLTKLRKKHWECEDAMKQIQNIIQQVQPGHVDENHEDVEQCIRAHFDDLMNWLNRRKKMMLMDLDEQCENKQKWLMQQMQTMTQKQEQLEHCC

NFTNWAIASGSSTALLYSKRLITFQLRHILKA
.|..||. .|..|..|.||.||.||..| .|.
QFCQWALNMGDCTEFLQSKKLIIFQCCHLHKQ

PHD TIF1g.AA PHD 902-947 38 1.2e-16 53.58 Pfam 1-54 (54) Show / Hide
Range on Protein: 902-947
Range on HMM: 1-54/54
Sequence Identity: 38% (21 aa)

WCAVCQN-----GGDLLCCE-KCPKVFHLTCHVPTLL--SFPSGDWICTFCRDI
.|.|||      .||..||. .||. ||. || |.|     |.|.|.|. |.  
YCCVCQKCDWDDDGDMICCDNGCPRWFHQYCHGPPLEPEEIPEGEWYCPRCKCC

PHD TIF1g.AA PHD 902-945 35 1.7e-13 52.07 SMART 1-39 (39) Show / Hide
Range on Protein: 902-945
Range on HMM: 1-39/39
Sequence Identity: 35% (16 aa)

WCAVCQNGGDLLCCE-KCPKVFHLTCHVPTLLSFPSGDWICTFCR
.| ||.  | ...|. .|.. .|. |. |.|.  |.| |.|  ||
YC-VCGK-G-MIQCDPGCDRWYHQ-CLGPPLE-PPDG-WYCPRCR

Zf-C3HC4 TIF1g.AA zf-C3HC4 920-944 28 3.63551 1.53 Pfam 26-48 (48) Show / Hide
Range on Protein: 920-944
Range on HMM: 26-48/48
Sequence Identity: 28% (7 aa)

KVFHLTCHVPTLLSFPSGDWICTFC
|.|. .| .  . .  || . | .|
KWFCHSCIKRWWNH--SGNTQCPIC

BROMO TIF1g.AA BROMO 972-1095 33 1.5e-32 115.38 SMART 1-118 (118) Show / Hide
Range on Protein: 972-1095
Range on HMM: 1-118/118
Sequence Identity: 33% (46 aa)

SPVDQRKCERLLLYLYCHELSI------------EFQEPVPVS---IPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMK
.|  |.||..||  ..||. .              |..||...   .|.||.|||.||||.|.||||.. .    | ...||.|..|.|.||  .||   
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQY---QSMEEFVDDFMLMFNNCMTYNE---

VVQVYADTQEINLKGDSEVAKAGKAVALYFEDKLSEIYS
               |||| |..|    .||.|. |.. 
--------------PDSEVYKMAKKLQKFFEEKWREFPP

Bromodomain TIF1g.AA Bromodomain 979-1064 30 1.4e-28 95.61 Pfam 1-89 (89) Show / Hide
Range on Protein: 979-1064
Range on HMM: 1-89/89
Sequence Identity: 30% (28 aa)

CERLLL--YLYCHELSIEFQEPV---PVSIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQ-IPDDFVADVRLIFKNCERFNEMMKVVQVYADT
|....   |.. |...  |..||   ....|.||.|||.||||||...||   ....|.  ...| .|..|...||...|.   .. ..|..
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKL---KNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK