Gene 11424 (Tetrahymena)

11424

Species: Tetrahymena
Alias: 3.m01741, 3824.m03179, 1126, PreTt11424, TTHERM_00052440, 11424
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
11424.AA Protein None 797 None Fasta, JSON
11424.kin_dom Protein Kinase Domain None 108 None Fasta, JSON
11424.NA RNA None 2394 None Fasta, JSON

Protein domain

Protein domains of 11424.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11424.AA HisK 436-533 25 8.1e-31 107.77 In-house 28-164 (164) Show / Hide 
Range on Protein: 436-533
Range on HMM: 28-164/164
Sequence Identity: 25% (35 aa)

SQRQIAISTE--------------------------VQSPNELQISVVDTGIGMPQSLKINLQDKSQNFQF-------ETRQPEKKNMRHGIGLGLDVSK
.| .| |. |                          .|..| .|||| |||.|||.... .. .. .|...        . . .|||..||.|||| ...
FQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICN

RLIRLITKE------DSLSVNSEQNLGTTITFKMLLN
.|.... .|      ....| ||.. |.| .|... |
NLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
HisKA 11424.AA HisKA 360-427 21 1.7e-12 46.54 Pfam 1-69 (69) Show / Hide 
Range on Protein: 360-427
Range on HMM: 1-69/69
Sequence Identity: 21% (15 aa)

YKNSVMNTITHDLKTPLNGIQLILGSSLE-GNKTQKKELKESIKNALVQGHLLESRINDLLDYSKLVHA
 |.  . .. |.|.|||..|.. .   .. .... .....| .. .. ... ... ||||||.|.. . 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 11424.AA HisKA 360-427 17 1.9e-11 45.29 SMART 1-89 (89) Show / Hide 
Range on Protein: 360-427
Range on HMM: 1-89/89
Sequence Identity: 17% (16 aa)

YKNSVMNTITHDLKTPLNGIQLILGSSLE----------GNKTQKK-----------ELKESIKNALVQGHLLESRINDLLDYSKLVHA
 |.  . .. |.|.|||..|.. .   ..          .. . ..           | .| .. .. ... ... ||||||.|.. . 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HATPase_c 11424.AA HATPase_c 426-533 18 1e-07 29.06 Pfam 20-120 (120) Show / Hide 
Range on Protein: 426-533
Range on HMM: 20-120/120
Sequence Identity: 18% (24 aa)

HAVEDSSDVKSQRQIAISTEVQSPNELQISVVDTGIGMPQ---------------------SLKINLQDKSQNFQFETRQPEKKNMRHG--IGLGLDVSK
|. |.        .| .. . .  ....|.| |.|.|.|                      .                       .. |   |||| ...
HTPEG-------GHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-------------------SR-RKYGGGLTGLGLYICR

RLIRLITKEDSLSVNSEQNLGTTITFKMLLN
|....   .  ..|.|| . |||.||.  | 
RIVEQHGGT--IWVESEPGGGTTFTFTLPLE
HATPase_c 11424.AA HATPase_c 406-534 15 0.000674 7.93 SMART 1-130 (130) Show / Hide 
Range on Protein: 406-534
Range on HMM: 1-130/130
Sequence Identity: 15% (26 aa)

VQGHLLESRINDLLDYSKLVHAVEDSSD----------VKSQRQIAISTEVQSPNELQISVVDTGIGMPQ-----------------------SLKINLQ
    .|.  .. |||     .|.. . .            .. .| .. .       .|.| |.|.|.|.                       |      
GDPDRLRQVLWNLLD-----NAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS------

DKSQNFQFETRQPEKKNMRHG--IGLGLDVSKRLIRLITKEDSLSVNSEQNLGTTITFKMLLNY
          .....   . |   |||| ..||....   .  ..|.      ||.||.  |  
--------RMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
Response_reg 11424.AA Response_reg 595-638 17 0.010198 12.3 Pfam 1-43 (115) Show / Hide 
Range on Protein: 595-638
Range on HMM: 1-43/115
Sequence Identity: 17% (8 aa)

IMIVDDTSFNIIALQNYIQKILQGKC-IIDVAYNGLQAINIYKKR
..||||   .  .|......  .  . ....|..| .|... ...
VLIVDDHPLMREGLRQILEQ--KEGYEVVAEADDGEEALEWWQEH
Response_reg 11424.AA Response_reg 709-786 33 1.2e-14 55.0 Pfam 42-115 (115) Show / Hide 
Range on Protein: 709-786
Range on HMM: 42-115/115
Sequence Identity: 33% (27 aa)

KSPYDTIFMDINMPIMDGYQAITTI-RNLE-KSCGMEYPSFIAVVTAFGEECDRQDSINIGANYHITKPLKQEQLKLILD
.  .| |.|||||| |||......| |...  .        | ..||.|.| |..  .  |||..|||| ....|. ...
EHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR
REC 11424.AA REC 675-785 20 1e-06 29.37 SMART 1-150 (150) Show / Hide 
Range on Protein: 675-785
Range on HMM: 1-150/150
Sequence Identity: 20% (34 aa)

N---IVNDI----NCSSEMNS-----QICERYKKMS-------SLGRKENFN------------LKS--------------PYDTIFMDINMP-------
    || |         || .     |.  .   .          .   .              |..              |.| |.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGYQAITTIRNLEKSCGMEYPSFIAVVTAFGEECDRQDSINIGANYHITKPLKQEQLKLIL
 |||....  ||             | ..||...| ||.  .  ||.  |||| ..|.|   .
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI