Gene 13282 (Tetrahymena)

13282

Species: Tetrahymena
Alias: TTHERM_00070920, 4.m00681, 3707.m00316, 443, PreTt13282, 13282
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
13282.AA Protein None 909 None Fasta, JSON
13282.kin_dom Protein Kinase Domain None 114 None Fasta, JSON
13282.NA RNA None 2730 None Fasta, JSON

Protein domain

Protein domains of 13282.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 13282.AA HisKA 317-473 12 2.6e-08 34.88 SMART 1-89 (89) Show / Hide 
Range on Protein: 317-473
Range on HMM: 1-89/89
Sequence Identity: 12% (22 aa)

YKDRLLATVSHDLKTPLNCIISVTDYLKTNLQQEMQTYSEQSSQYQNQSDANGSTKYLNQSDINGSYIRYPNQLSLFSQKNQKNQNLLDSKLEVTNSNCI
 |...||..||.|.|||. |.  .. |.... .                                                                   
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYK-------------------------------------------------------------------

YNSESNQIQNQKMSSNKQNHQQQKKQS----------------LEYLQLIYNNSMMLLNMINDILDYSKFNNK
                 |  ..  . .                 |||. |.. .  ....|||.||.|.  . 
-----------------QRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 13282.AA HisKA 317-354 33 3.4e-05 21.08 Pfam 1-42 (69) Show / Hide 
Range on Protein: 317-354
Range on HMM: 1-42/69
Sequence Identity: 33% (14 aa)

YKDRLLATVSHDLKTPLNCIISVTDYLKT--NLQQEM--QTY
 | ..||..||.|.|||. |.  .. |..  .|  |   . |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREY
HisKA 13282.AA HisKA 445-473 34 0.00038 17.44 Pfam 41-69 (69) Show / Hide 
Range on Protein: 445-473
Range on HMM: 41-69/69
Sequence Identity: 34% (10 aa)

EYLQLIYNNSMMLLNMINDILDYSKFNNK
|||. |.. .  ....|||.||.|.  . 
EYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 13282.AA HisK 499-612 33 2.2e-54 186.98 In-house 1-164 (164) Show / Hide 
Range on Protein: 499-612
Range on HMM: 1-164/164
Sequence Identity: 33% (55 aa)

TDRNRVKQIIMNLVSNSLKFTIQG------YIKVSAV---------------ENLE----------QNLVGISVEDTGIGMSDKIKQQLFKDYQ------
.| ||.|||..||.||.|||| .|      |||...                ....          .||. |||.|||.||........|| ..      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFNQENL--NQNGIGLGLTICKKFVEMLGKG------TGFSVDSAEGQGSKFYFEILKS
     |||..|   ||.|.|||||||......||.        |..| | .|.||.|.|.|.. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 13282.AA HATPase_c 499-612 30 1.4e-25 91.25 Pfam 1-120 (120) Show / Hide 
Range on Protein: 499-612
Range on HMM: 1-120/120
Sequence Identity: 30% (38 aa)

TDRNRVKQIIMNLVSNSLKFTIQ-GYIKVSAVENLEQNLVGISVEDTGIGMSD------KIKQQLFKDYQTFNQ--ENLNQNG--IGLGLTICKKFVEML
.|..|..|.. |||.|..|.| . | |.|.. .    . | |.|||.|.|...      .  ...|  .... .     .  |   ||||.||...||..
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQH

GKGTGFSVDSAEGQGSKFYFEILKS
| ||  .|.| .|.|..| |.. . 
G-GT-IWVESEPGGGTTFTFTLPLE
Kinase 13282.AA HATPase_c 499-613 21 2.6e-22 81.36 SMART 1-130 (130) Show / Hide 
Range on Protein: 499-613
Range on HMM: 1-130/130
Sequence Identity: 21% (31 aa)

TDRNRVKQIIMNLVSNSLKFTIQ--------------GYIKVSAVENLEQNLVGISVEDTGIGMSD------KIKQQLFKDYQTFNQ---------ENLN
.|..|..|.. ||..|..|.| .              | |.|..          |.|||.|.|...      .. ...|  .... .          . .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

QNG--IGLGLTICKKFVEMLGKGTGFSVDSAEGQGSKFYFEILKSY
  |   ||||.|||..||..|    ..        ..|.|.. .. 
YGGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER
REC 13282.AA REC 786-902 20 1.3e-18 69.11 SMART 1-150 (150) Show / Hide 
Range on Protein: 786-902
Range on HMM: 1-150/150
Sequence Identity: 20% (33 aa)

INIMIVDDS----QYNLITLK------LHLNPISCV-------SIDEFLFAE-------EALKQFLYK-------------DYDIVFSDVQMP-------
..|.||||.    . .. .|.      . |    .         .||.  .|       |||...  .             ..|... |..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGIQFAHKIREKGQSIHQPLIIMVSADTQEKYDNELLGLSISAFISKPIVDKSKFQNMI
 ||||.....||          |||..| ..| .  . | .   ..|.||. ..  ..  |
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPE-ELLARI
Response_reg 13282.AA Response_reg 788-903 27 1.8e-13 50.82 Pfam 1-115 (115) Show / Hide 
Range on Protein: 788-903
Range on HMM: 1-115/115
Sequence Identity: 27% (32 aa)

IMIVDDSQYNLITLKLHLNPISCV-SIDEFLFAEEALKQFLYKDYDIVFSDVQMPIMDGIQFAHKI-REKGQSIHQPLIIMVSADTQEKYDNELLGLSIS
..||||.. ..  |.  |.  .   ...|.  .||||...  ...|... |..|| |||.... .| |... . . . |||..|  .| .  | | . . 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ-TPIIMCTAHGDEDDAVEALQAGAN

AFISKPIVDKSKFQNMIY
 .|.||. |. .  ..| 
DYITKPF-DPDELHAAIR