Gene 15614 (Tetrahymena)

15614

Species: Tetrahymena
Alias: 15614, PreTt15614, 589, TTHERM_00295040, 27.m00274, 3692.m00077
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
15614.AA Protein None 951 None Fasta, JSON
15614.kin_dom Protein Kinase Domain None 115 None Fasta, JSON
15614.NA RNA None 2856 None Fasta, JSON

Protein domain

Protein domains of 15614.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 15614.AA HisKA 491-557 21 5.8e-09 37.01 SMART 1-89 (89) Show / Hide 
Range on Protein: 491-557
Range on HMM: 1-89/89
Sequence Identity: 21% (19 aa)

YKEKLLSMITHNLKTPLNGIICILESIVLQQ--------QNAHIDQ--------------QNLNAVLQSSKLLSYMINDLIDYSCIIKG
 |...|... | |.|||..|.  .| .  ..        ...  .|              . |. ...... .. .|||| |.| |  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 15614.AA HisKA 491-557 27 7.3e-09 33.88 Pfam 1-69 (69) Show / Hide 
Range on Protein: 491-557
Range on HMM: 1-69/69
Sequence Identity: 27% (19 aa)

YKEKLLSMITHNLKTPLNGIICILESIVLQQQNAHIDQ---QNLNAVLQSSKLLSYMINDLIDYSCIIKG
 |...|... | |.|||..|.  .| .    ...  .|   . |. ...... .. .|||| |.| |  |
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 15614.AA HisK 605-719 26 5.4e-38 132.55 In-house 1-164 (164) Show / Hide 
Range on Protein: 605-719
Range on HMM: 1-164/164
Sequence Identity: 26% (44 aa)

NDQQRFMQILVNLISNSLKYTFQG------NICLSLENCQDS-------------------------ESIQIIVSDTGIGMRESTVKKLNLFSE------
.|..|..|||.|||||.||.|..|      .|....|....                          . ||| |.|||.|| |...||.  . .      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------SIQSEFDYQSGLGLGLQLINNLIQKIGPT------QSLKVKKNSQDGGTIVKFSVYKD
       . |.....|.| ||||   |||....||.      ....|.   .. |.. .| .|..
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQS-EVGKGSTFSFYIYNN
Kinase 15614.AA HATPase_c 605-720 18 2.9e-15 57.97 SMART 1-130 (130) Show / Hide 
Range on Protein: 605-720
Range on HMM: 1-130/130
Sequence Identity: 18% (27 aa)

NDQQRFMQILVNLISNSLKYTFQ--------------GNICLSLENCQDSESIQIIVSDTGIGMRE------STVKKLNLFSESIQ---------SEFDY
.|. |..|.| ||..|..|.| .              | | ....        .| |.|.|.|. .        ....     .           |    
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

QSG--LGLGLQLINNLIQKIGPTQSLKVKKNSQDGGTIVKFSVYKDI
 .|   |||| . ...... | |  ..|        | . |.. . .
YGGGLTGLGLSICKRIVEQHGGT--IWVE-------TTFTFTLPLER
Kinase 15614.AA HATPase_c 605-719 20 4.2e-15 54.81 Pfam 1-120 (120) Show / Hide 
Range on Protein: 605-719
Range on HMM: 1-120/120
Sequence Identity: 20% (28 aa)

NDQQRFMQILVNLISNSLKYTFQ-GNICLSLENCQDSESIQIIVSDTGIGMRE----------------STVKKLNLFSESIQSEFDYQSG--LGLGLQL
.|. |..|.. ||..|..|.| . | | .... .   . ..| |.|.|.|. .                 .....        |  .  .|   |||| .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--------SR-RKYGGGLTGLGLYI

INNLIQKIGPTQSLKVKKNSQ-DGGTIVKFSVYKD
 . .... | |    .  .|. .||| . | . ..
CRRIVEQHGGT----IWVESEPGGGTTFTFTLPLE
REC 15614.AA REC 817-946 25 8.3e-22 79.69 SMART 1-150 (150) Show / Hide 
Range on Protein: 817-946
Range on HMM: 1-150/150
Sequence Identity: 25% (41 aa)

KKIMIVDDT----VFNILAMK------ILFKNISNL-------VINEAYNGE-------QAVNLFKSAIQQEEFKQSTNLFIPDIIFMDINMP-------
..|.||||       .  ...      .|..            |. || .||       .|..|...  ...|   . ..  ||.|.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IKDGIQATKEINELALVHKIQVKIITVSAFDQESDRENFLIAGSHYHIAKPIKIESLVEGL
  |||.....|           .|| ..|.|.|.||.  | ||    | ||...| |.. .
GMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 15614.AA Response_reg 819-947 26 5.2e-20 74.25 Pfam 1-115 (115) Show / Hide 
Range on Protein: 819-947
Range on HMM: 1-115/115
Sequence Identity: 26% (35 aa)

IMIVDDTVFNILAMKILFKNISNL-VINEAYNGEQAVNLFKSAIQQEEFKQSTNLFIPDIIFMDINMPIKDGIQATKEI-NELA-LVHKIQVKIITVSAF
..||||   .  ... .... . . |. ||..||.|....      .| .       ||.|.||||||  ||......|  ..        ..|| ..|.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW------QEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ----TPIIMCTAH

DQESDRENFLIAGSHYHIAKPIKIESLVEGLH
..|.|..  | || ...|.||.... |.. . 
GDEDDAVEALQAGANDYITKPFDPDELHAAIR