Gene 15969 (Tetrahymena)

15969

Species: Tetrahymena
Alias: 741, 15969, TTHERM_00320520, PreTt15969, 32.m00213
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
15969.AA Protein None 1332 None Fasta, JSON
15969.kin_dom Protein Kinase Domain None 92 None Fasta, JSON
15969.NA RNA None 3999 None Fasta, JSON

Protein domain

Protein domains of 15969.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 15969.AA HisKA 461-526 24 2.5e-12 48.21 SMART 1-89 (89) Show / Hide 
Range on Protein: 461-526
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

YKDQILAIATHDLKTPLNNIICSVESMKL-----------RQDNTNI------------SEQLELVSVSVKQMMNIIKDILDYSALNKG
 |.| || . |.|.|||. |.  .| ..              |   .             | || .  ....| ..| |.||.| .  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 15969.AA HisKA 461-526 31 3.6e-12 45.41 Pfam 1-69 (69) Show / Hide 
Range on Protein: 461-526
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

YKDQILAIATHDLKTPLNNIICSVESMKL--RQDNTN-ISEQLELVSVSVKQMMNIIKDILDYSALNKG
 | | || . |.|.|||. |.  .| ..    .|    . | || .  ....| ..| |.||.| .  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 15969.AA HisKA 536-553 22 11.556497 1.82 Pfam 52-69 (69) Show / Hide 
Range on Protein: 536-553
Range on HMM: 52-69/69
Sequence Identity: 22% (4 aa)

RLSDLIKQIFQLFKLHAQ
|...|| .. .. .. |.
RMQRLINDLLDFSRIEAG
Kinase 15969.AA HisK 574-690 32 4.2e-47 162.81 In-house 1-164 (164) Show / Hide 
Range on Protein: 574-690
Range on HMM: 1-164/164
Sequence Identity: 32% (53 aa)

SDPSRLVQIFNNLIANSLKFTVKG------SIHIKFK-------------SNPNDR-----------NVIHISITDTGVGIPQQYVDQIFKPFQ------
|||.|. ||  ||| |.|||| ||      .| ||..             .. ..            |.| ||. |||.|.|.. . .|||.|.      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFNHTEG-LKTQGVGLGLIICKTLVRQLGPSQ-----QRIGLKTQQNIGSKICFDFYRN
     |||| .. ....|.||||.||. |...|||..     . | .. ....||.  |  | |
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 15969.AA HATPase_c 574-665 32 6e-24 85.59 Pfam 1-98 (120) Show / Hide 
Range on Protein: 574-665
Range on HMM: 1-98/120
Sequence Identity: 32% (33 aa)

SDPSRLVQIFNNLIANSLKFTVK-GSIHIKFKSNPNDRNVIHISITDTGVGIPQ------QYVDQIFKPFQTFNH-TEGLKTQG--VGLGLIICKTLVRQ
 || ||.|.. ||. |..|.| . | |... .  .   . ..|...|.|.|||       . ...|| ||...       |..|   |||| ||. .|.|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ

LG
.|
HG
Kinase 15969.AA HATPase_c 574-691 24 4.5e-23 83.91 SMART 1-130 (130) Show / Hide 
Range on Protein: 574-691
Range on HMM: 1-130/130
Sequence Identity: 24% (36 aa)

SDPSRLVQIFNNLIANSLKFTVK--------------GSIHIKFKSNPNDRNVIHISITDTGVGIPQ------QYVDQIFKPFQTFNH--------TEGL
 || || |...||. |..|.| .              | |... .         .|...|.|.|||.      . ...|| ||...              
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

KTQG--VGLGLIICKTLVRQLGPSQQRIGLKTQQNIGSKICFDFYRNI
|..|   |||| ||| .|.|.| .   | .       ....| . . .
KYGGGLTGLGLSICKRIVEQHGGT---IWVE------TTFTFTLPLER
REC 15969.AA REC 1199-1322 20 5.3e-20 73.7 SMART 1-150 (150) Show / Hide 
Range on Protein: 1199-1322
Range on HMM: 1-150/150
Sequence Identity: 20% (34 aa)

TNALIIDDE----YVHFVIFS--QLLKNISQNYHFQ--------FDYATNGQ-------EALDLIEKKPESY----------YKIVFVDGSMP-------
 . ||.||.     |   . .   .. .. .   ..         | | .|.       |||.|..... ..          . ....|  ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMSGYDFIQRIRQYEQNKQYLQKHHIIGVTGGGE-RDKNQFLSAGADYYIQKPVQTSILIEYL
 |.|.....|||             || .|. ..  |. . | |||| || ||..   |.. .
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 15969.AA Response_reg 1201-1323 27 3.1e-12 46.39 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1201-1323
Range on HMM: 1-115/115
Sequence Identity: 27% (35 aa)

ALIIDDEYVHFVIFSQLLKNISQNYHF-QFDYATNGQEALDLIEKKPESYYKIVFVDGSMPVMSGYDFIQRI-RQYE-QNKQYLQKHHIIGVTGGG-ERD
 ||.||. .   .. |.|..    . .   . |..|.|||......    . ... | .|| |.|.....|| || .  .        || .|. | | |
VLIVDDHPLMREGLRQILEQ---KEGYEVVAEADDGEEALEWWQEHH---PDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDEDD

KNQFLSAGADYYIQKPVQTSILIEYLN
. . | |||..|| ||.    |.. ..
AVEALQAGANDYITKPFDPDELHAAIR