Gene 18664 (Tetrahymena)

18664

Species: Tetrahymena
Alias: 55.m00219, TTHERM_00467620, 18664, PreTt18664, 3710.m00068, 424
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
18664.AA Protein None 1463 None Fasta, JSON
18664.kin_dom Protein Kinase Domain None 117 None Fasta, JSON
18664.NA RNA None 4392 None Fasta, JSON

Protein domain

Protein domains of 18664.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 18664.AA HisKA 929-990 23 1.7e-11 45.43 SMART 1-89 (89) Show / Hide 
Range on Protein: 929-990
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

KKSKMVSFVSHELRTPLNSIIAMLESMKN--------------KPDI-------------DYIETALMNSKYLLCISNDLLDLAQIKVN
 |..... .||||||||..|....| ...               ...             .|.||..  ..... . ||||||..|  .
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 18664.AA HisKA 929-990 28 2.1e-11 42.71 Pfam 1-69 (69) Show / Hide 
Range on Protein: 929-990
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

KKSKMVSFVSHELRTPLNSIIAMLESMKN-----KPD--IDYIETALMNSKYLLCISNDLLDLAQIKVN
 |..... .||||||||..|....| ...      ..   .|.||..  ..... . |||||...|  .
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 18664.AA HisK 1037-1153 34 7.4e-53 181.91 In-house 1-164 (164) Show / Hide 
Range on Protein: 1037-1153
Range on HMM: 1-164/164
Sequence Identity: 34% (56 aa)

SDKNRVRQVLINLIGNAFKFTLTG------SITIKVQIIN--------------------------NVLFQVHVIDTGIGIKETDLNKLFKTFGKLDG--
||.||..|.|||||.|| |||  |      .|.|||..||                          . |.|..|.|||.|..| ...|.|| ||. |.  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------EESVKLNEQGVGLGLVISNMIAFSLSEQKE-----GLTVKSEYSKGTSFQFKIQDW
        ... |.| .|.||||.|.|..|  |.....     |..|.||. ||..| |.|...
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 18664.AA HATPase_c 1037-1153 30 1.9e-20 73.37 Pfam 1-120 (120) Show / Hide 
Range on Protein: 1037-1153
Range on HMM: 1-120/120
Sequence Identity: 30% (38 aa)

SDKNRVRQVLINLIGNAFKFTLT-GSITIKVQIINNVLFQVHVIDTGIGIKE------TDLNKLFKTFGKLDGEESVKLNEQG--VGLGLVISNMIAFSL
 | .|..||. ||..|| |.| . | ||..|   .    .. |.|.|.|| .       |....|  |.. |.  |   . .|   |||| |...|.  .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVEQH

SEQKEGLTVKSEYSKGTSFQFKIQDW
  .   ..| ||  .|| | |..   
GGT---IWVESEPGGGTTFTFTLPLE
Kinase 18664.AA HATPase_c 1037-1154 25 2.7e-20 74.68 SMART 1-130 (130) Show / Hide 
Range on Protein: 1037-1154
Range on HMM: 1-130/130
Sequence Identity: 25% (37 aa)

SDKNRVRQVLINLIGNAFKFTLT--------------GSITIKVQIINNVLFQVHVIDTGIGIKE------TDLNKLFKTFGKLDGEE------SVKLNE
 | .|.||||.||..||.|.| .              | ||..|        .. |.|.|.|| .       |....|  |.. |...      |   . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QG--VGLGLVISNMIAFSLSEQKEGLTVKSEYSKGTSFQFKIQDWN
.|   |||| |...|.  .  .   ..|       | |.|..    
GGGLTGLGLSICKRIVEQHGGT---IWVE------TTFTFTLPLER
REC 18664.AA REC 1329-1454 21 6.6e-20 73.38 SMART 1-150 (150) Show / Hide 
Range on Protein: 1329-1454
Range on HMM: 1-150/150
Sequence Identity: 21% (35 aa)

GQVLIVDDN----MNNIVAMK------CLLSAICPE------IKCNYAIRGQ-------GAEDLVRNRYMQQKDE------GYAIIFMDIVMP-------
  .|||||.      .  ...       ||.    |      . .  |  |.        | .|...   .. |.       . .|.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

EQDGITTGEKIYQYLQENNITNTKIIACSGYDDEQEKRKCLDVGMSDYLVKPVFKDKLTQVV
. |||.. ..|            .||.....|||. ....|..|. ||..||.  . | ...
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 18664.AA Response_reg 1384-1455 31 5.9e-14 52.55 Pfam 47-115 (115) Show / Hide 
Range on Protein: 1384-1455
Range on HMM: 47-115/115
Sequence Identity: 31% (23 aa)

IIFMDIVMPEQDGITTGEKIYQYLQ-ENNITNTKIIACSGYDDEQEKRKCLDVGMSDYLVKPVFKDKLTQVVQ
.|.||| ||. ||... ..| . ..  .    |.||.|....||. . ..|..|. ||..||. .|.| . ..
LIIMDINMPGMDGLELCRRIRRQHPHPQ----TPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR
Response_reg 18664.AA Response_reg 1331-1337 85 15.318894 0.92 Pfam 1-7 (115) Show / Hide 
Range on Protein: 1331-1337
Range on HMM: 1-7/115
Sequence Identity: 85% (6 aa)

VLIVDDN
||||||.
VLIVDDH