Gene 19275 (Tetrahymena)

19275

Species: Tetrahymena
Alias: 3691.m00052, TTHERM_00299800, PreTt19275, 28.m00234, 19275, 598
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
19275.AA Protein None 1069 None Fasta, JSON
19275.kin_dom Protein Kinase Domain None 115 None Fasta, JSON
19275.NA RNA None 3210 None Fasta, JSON

Protein domain

Protein domains of 19275.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 19275.AA HisKA 162-224 30 4e-10 38.27 Pfam 1-66 (69) Show / Hide 
Range on Protein: 162-224
Range on HMM: 1-66/69
Sequence Identity: 30% (20 aa)

YKDKLLATVSHDLKTPLSAMISLVESCFI-SIKDEEI--KKILQDTLKVSDLLSHLINDIQDYGQI
 | ..||..||.|.|||.|.. ..| .   . .|.|   ...|.  .. .. ...||||. |. .|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRI
HisKA 19275.AA HisKA 162-227 23 1.3e-08 35.84 SMART 1-89 (89) Show / Hide 
Range on Protein: 162-227
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

YKDKLLATVSHDLKTPLSAMISLVESCFI----------SIKDEEI-------------KKILQDTLKVSDLLSHLINDIQDYGQIYNC
 |...||..||.|.|||.|.. ..| .            .  |.|              ...|.  .. .| ...||||. |. .| . 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 19275.AA HisK 279-393 35 1.7e-60 207.27 In-house 1-164 (164) Show / Hide 
Range on Protein: 279-393
Range on HMM: 1-164/164
Sequence Identity: 35% (58 aa)

SDSQRLKQILLNLIGNAIKFT------MKGSIKVFFE--------------ISSDQET-----------IEITVTDTGIGIPQEIQQKLFKEYN------
|| .|.||||.|||.||.|||      ..|.||. .|              |...||.           |.|.| |||.|.|.|.|.|.|| ..      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFDTPSG-LNRNGVGLGLYMSKKLAGLLGPS------ENIKLVSKEGEGSSFSFVIFKN
     ||.. .. .|..|.||||.....||..|||.       .|...|..|.||.|||.|..|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 19275.AA HATPase_c 279-393 30 2.6e-26 93.78 Pfam 1-120 (120) Show / Hide 
Range on Protein: 279-393
Range on HMM: 1-120/120
Sequence Identity: 30% (38 aa)

SDSQRLKQILLNLIGNAIKFTMK-GSIKVFFEISSDQETIEITVTDTGIGIPQ------EIQQKLFKEYNTFDT-PSGLNRNG--VGLGLYMSKKLAGLL
 |  ||.|...||..||||.| . | |.|  .     . ..|||.|.|.|||       | ....|  . ..|   .  .. |   |||||...... ..
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQH

GPSENIKLVSKEGEGSSFSFVIFKN
| .  | . |..|.|. |.| . . 
GGT--IWVESEPGGGTTFTFTLPLE
Kinase 19275.AA HATPase_c 279-396 24 4.6e-24 87.2 SMART 1-130 (130) Show / Hide 
Range on Protein: 279-396
Range on HMM: 1-130/130
Sequence Identity: 24% (36 aa)

SDSQRLKQILLNLIGNAIKFTMK--------------GSIKVFFEISSDQETIEITVTDTGIGIPQ------EIQQKLFKEYNTFDT--------PSGLN
 |  ||.|.|.||..||||.| .              | |.|  .        .|||.|.|.|||.      |.....|  . ..|          .  .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

RNG--VGLGLYMSKKLAGLLGPSENIKLVSKEGEGSSFSFVIFKNLQE
. |   ||||. .|... ..| .  |..           |..   |..
YGGGLTGLGLSICKRIVEQHGGT--IWVE--------TTFTFTLPLER
Response_reg 19275.AA Response_reg 769-807 25 0.090139 8.91 Pfam 1-40 (115) Show / Hide 
Range on Protein: 769-807
Range on HMM: 1-40/115
Sequence Identity: 25% (10 aa)

ILVVDDEEISHKVFQHQFKQFSTV-KIHSAYNGEEAISKI
.|.|||...  ....  ..| .   .. .|..||||. ..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW
Response_reg 19275.AA Response_reg 992-1063 32 5e-11 42.07 Pfam 48-115 (115) Show / Hide 
Range on Protein: 992-1063
Range on HMM: 48-115/115
Sequence Identity: 32% (24 aa)

IFMDYSMPLMDGLQTIQKI-RQLQ-SDKLITQQIFIFMVSGYDQKSDANEFLSNGADGIISKPVSQLKIAQAFN
|.|| .|| ||||.....| ||.. ..      . | |........|| | |  ||...|.||... .. .| .
IIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR
REC 19275.AA REC 961-1062 15 2e-05 19.93 SMART 1-150 (150) Show / Hide 
Range on Protein: 961-1062
Range on HMM: 1-150/150
Sequence Identity: 15% (25 aa)

K-------N-----NQQKIIK------NESKKLLVN----------------------QELKLQQPQ-------------QFSYIFMDYSMP-------L
.       .      ......      .  .|.                         . |.| | .             ..  |.||  ||        
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEADGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDGG

MDGLQTIQKIRQLQSDKLITQQIFIFMVSGYDQKSDANEFLSNGADGIISKPVSQLKIAQAF
|||......||             | |....|. .|. . |  |||. |.||...  . .. 
MDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI