25684

Species: Tetrahymena
Alias: 155, PreTt25684, TTHERM_00583470, 79.m00198, 3827.m00914, 25684
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
25684.AA Protein None 1553 None Fasta, JSON
25684.kin_dom Protein Kinase Domain None 123 None Fasta, JSON
25684.NA RNA None 4662 None Fasta, JSON

Protein domain

Protein domains of 25684.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 25684.AA HisKA 795-863 32 3e-13 49.15 Pfam 1-69 (69) Show / Hide
Range on Protein: 795-863
Range on HMM: 1-69/69
Sequence Identity: 32% (23 aa)

DKMRIFASLSHELRTPLNCSISMLEVIRENVEQINPEL-IEEYLNPALFSNKLLLNQINDLLDYVQMDSG
 | . .|..||||||||.  . ..|.... ..  .||  ..|||. .. . . ....||||||. ....|
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 25684.AA HisKA 795-863 25 3.4e-13 51.07 SMART 1-89 (89) Show / Hide
Range on Protein: 795-863
Range on HMM: 1-89/89
Sequence Identity: 25% (23 aa)

DKMRIFASLSHELRTPLNCSISMLEVIRENV--------EQINPELI------------EEYLNPALFSNKLLLNQINDLLDYVQMDSG
 | . .|..||||||||.  . ..|......           .|| .            .|||. .. . . ....||||||. ....|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 25684.AA HisK 910-1032 35 2.5e-61 210.08 In-house 1-164 (164) Show / Hide
Range on Protein: 910-1032
Range on HMM: 1-164/164
Sequence Identity: 35% (58 aa)

SDPNRIRQILLNFLSNSLKFTKKG------YIEIGITLFDNK------------------------KGLLKVYVKDTGIGITKENLDTIFDFCGKV----
||||||.|||.|..||.||||.||      ||.| .......                        |.|....|.|||.|...|..  ||...|..    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----NYNQKDQHLNRQGCGLGLTISNSIAKGLVKNGE--DDGGIKVESDYGHGSTFSILIQDM
     ..|.... .|..||||||||.|..|||| ....  . .||.|.|..|.|||||..|.. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 25684.AA HATPase_c 910-1032 25 2.3e-19 69.63 Pfam 1-120 (120) Show / Hide
Range on Protein: 910-1032
Range on HMM: 1-120/120
Sequence Identity: 25% (35 aa)

SDPNRIRQILLNFLSNSLKFTKK-GYIEIGITLFDNKKGLLKVYVKDTGIGITK------ENLDTIFD-------FCGKVNYNQKDQHLNRQG--CGLGL
 ||.|..|...|...|..|.|.. | |.. ..  |   . . . |.|.|.||..      |....||.                     ...|   ||||
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---------SR-RKYGGGLTGLGL

TISNSIAKGLVKNGEDDGGIKVESDYGHGSTFSILIQDM
.|.. |.. .   |.    | |||  |.|.||.. .   
YICRRIVEQHG--GT----IWVESEPGGGTTFTFTLPLE

Kinase 25684.AA HATPase_c 910-1033 22 8.6e-18 66.35 SMART 1-130 (130) Show / Hide
Range on Protein: 910-1033
Range on HMM: 1-130/130
Sequence Identity: 22% (34 aa)

SDPNRIRQILLNFLSNSLKFTKKGY------------IEIGITLFDNKKGLLKVYVKDTGIGITK------ENLDTIFDFCGKVNY-----NQKDQHLNR
 ||.|.||.|.| |.|..|.|..|.             .| ...         . |.|.|.||..      | ...||.  ...        .. .  ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QG--CGLGLTISNSIAKGLVKNGEDDGGIKVESDYGHGSTFSILIQDMS
.|   ||||.|...|.. .  .|.    |.||      .||.. .    
GGGLTGLGLSICKRIVEQH--GGT----IWVE------TTFTFTLPLER

REC 25684.AA REC 1419-1545 21 1.7e-18 68.7 SMART 1-150 (150) Show / Hide
Range on Protein: 1419-1545
Range on HMM: 1-150/150
Sequence Identity: 21% (36 aa)

PQFMIVDDN----QFNTYALS------KILGQYFFT--------FQCLSDGF-------SAIEEVQSLYQKSCCKA------PKIIFMDIEMP-------
.  .||||.    . .  .|.      ..| .  ..          .  ||         |.| .|.. .|           | .|.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

MKNGYETAVEINQFYEQVALPVQYQPIIIACTAYVGQEDVDAAMQSGMKDFINKPILKNGLESLI
  .|.|.. .|                ||..||. . ||. .|...|. |.| ||.  . |   |
GMDGIELCRRIR--------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 25684.AA Response_reg 1421-1546 30 6.9e-11 41.56 Pfam 1-115 (115) Show / Hide
Range on Protein: 1421-1546
Range on HMM: 1-115/115
Sequence Identity: 30% (39 aa)

FMIVDDNQFNTYALSKILG-QYFF-TFQCLSDGFSAIEEVQSLYQKSCCKAPKIIFMDIEMPMKNGYETAVEI-NQFY-EQVALPVQYQPIIIACTAYVG
 .||||.. .  .| .||  .. .      .|| .|.| .| .        | .|.|||.||  .|.|.. .|  | .  |        . ||.|||.  
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ--------TPIIMCTAHGD

QEDVDAAMQSGMKDFINKPILKNGLESLIL
 .|. .|.| |. |.| ||. .. |   | 
EDDAVEALQAGANDYITKPFDPDELHAAIR