Gene 29191 (Tetrahymena)
29191
Sequence
Protein domains of 29191.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 29191.AA | HisK | 1601-1609 | 66 | 0.508705 | 0.32 | In-house | 156-164 (164) | Show / Hide |
Range on Protein: 1601-1609 Range on HMM: 156-164/164 Sequence Identity: 66% (6 aa) TFQFYIPQN || ||| .| TFSFYIYNN |
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| Kinase | 29191.AA | HisK | 1615-1731 | 24 | 1.8e-41 | 144.09 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 1615-1731
Range on HMM: 1-164/164
Sequence Identity: 24% (40 aa)
SDKKRVLQVLFEIIGNAIKYTNNG------FIQVKIKEQE--------------------------KGLIWVKVQDSGQGMSESQKHSLFSNKLIQ----
||. |. |.|. .|.||.|.|..| .| .|..... |.||.. |||.| ||.|.|.. .| . .
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH
-----YYSRERDFSKKNSAGLGLDFSRKVVGILGPF------HEIFIKSSEGVGSAFKFLLYSD
... .. ..... .|||| ... ...|||. ..| ..| .|.|| |.|..| .
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
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| Kinase | 29191.AA | HATPase_c | 1615-1731 | 24 | 1.2e-14 | 53.19 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 1615-1731 Range on HMM: 1-120/120 Sequence Identity: 24% (32 aa) SDKKRVLQVLFEIIGNAIKYTNN-GFIQVKIKEQEKGLIWVKVQDSGQGMSE------SQKHSLFS-------NKLIQYYSRERDFSKKNS--AGLGLDF | |. ||. ....||||.| | | |...... . ... |.|.| |... . .| .. .| |||| GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---------SR-RKYGGGLTGLGLYI SRKVVGILGPFHEIFIKSSEGVGSAFKFLLYSD .|..| .| .| . |..| |. | | | . CRRIVEQHG--GTIWVESEPGGGTTFTFTLPLE |
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| Kinase | 29191.AA | HATPase_c | 1615-1732 | 20 | 7e-08 | 33.42 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 1615-1732 Range on HMM: 1-130/130 Sequence Identity: 20% (30 aa) SDKKRVLQVLFEIIGNAIKYTNN--------------GFIQVKIKEQEKGLIWVKVQDSGQGMSE------SQKHSLFSNKLIQYYSRER---------- | .|. ||| ....||||.| | | |... .. |.|.| |... . .| . . | . GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIF-----EPFYRTDDSPSRMCPDS DFSKKNS--AGLGLDFSRKVVGILGPFHEIFIKSSEGVGSAFKFLLYSDY . .| |||| ....| .| .| . . | | | RSRKYGGGLTGLGLSICKRIVEQHG--GTIWVE------TTFTFTLPLER |
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| REC | 29191.AA | REC | 2316-2437 | 17 | 2.1e-16 | 61.72 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 2316-2437 Range on HMM: 1-150/150 Sequence Identity: 17% (28 aa) SYVLGVDDN----IFNLNILE------MVFKKCSNV-------IFHKAGNGE-------EALQKVKELK-------NSQNAY-YKVFLLDIQMP------ .| |||. .. .|. . ..| . . | .|| |||....|.. . . . . . ..||.|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED -IMDGYKTHSELKKLMKKKFIEHSPVFAVTAFAN--EKQICIQQGMEGFIEKPINMKLLINLM |||. . ... |. ..||... .. ....|. ..| ||.... |. . GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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| Response_reg | 29191.AA | Response_reg | 2318-2438 | 24 | 3e-12 | 46.43 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 2318-2438 Range on HMM: 1-115/115 Sequence Identity: 24% (31 aa) VLGVDDNIFNLNILEMVFK-KCSN-VIFHKAGNGEEALQKVKELKNSQNAYYKVFLLDIQMPIMDGYKTHSEL-KKLM-KKKFIEHSPVFAVTAFAN--E || |||. .. .| .. | |. | .|||||....|.. . . ..||.|| |||. . ... ... . |. ..||... VLIVDDHPLMREGLRQILEQKEGYEVVA-EADDGEEALEWWQEHH------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDEDD KQICIQQGMEGFIEKPINMKLLINLMF .. ..| |. ..| ||... |.. AVEALQAGANDYITKPFDPDELHAAIR |
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