3312

Species: Tetrahymena
Alias: 312, 3740.m00035, PreTt03312, 126.m00110, 3312, TTHERM_00765200
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
3312.AA Protein None 1646 None Fasta, JSON
3312.kin_dom Protein Kinase Domain None 187 None Fasta, JSON
3312.NA RNA None 4941 None Fasta, JSON

Protein domain

Protein domains of 3312.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3312.AA HisK 779-965 24 2e-44 153.88 In-house 1-164 (164) Show / Hide
Range on Protein: 779-965
Range on HMM: 1-164/164
Sequence Identity: 24% (52 aa)

HDQRRLLQILVNLISNSLKFTFKG------KIELIIDTPSDENNINLGSMHMFQNNQISTGRYSNSPSSNKNKQLDTRSLQSNLLFKNCKNQEIIQSNNN
 |..|. |||.|||||.||||.||      .|.....  ...|||                .| |  |                .|.......  . .  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNI----------------KY-N--S----------------IFIQKIQEN--M-V--

LIDKLADKKKLFKKEKHIRFTVVDSGIGMSHQKLQKLKRMLF--------------KKEIFNIQNSSGLGLTMCYSLIKQIGCQH-----THLEIQSEEN
.       . .......|...| |.|.||......|.. |.               .....| |.  |||||.|..|.|..|..|      ....|||..
Q-------E-QLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVG

IGTKFSFTIQQF
.|..||| |...
KGSTFSFYIYNN

Kinase 3312.AA HATPase_c 779-965 15 1.7e-14 52.65 Pfam 1-120 (120) Show / Hide
Range on Protein: 779-965
Range on HMM: 1-120/120
Sequence Identity: 15% (32 aa)

HDQRRLLQILVNLISNSLKFTFK-GKIELIIDTPSDENNINLGSMHMFQNNQISTGRYSNSPSSNKNKQLDTRSLQSNLLFKNCKNQEIIQSNNNLIDKL
 |..|| |.. ||..|..|.| . |.|.. ...                                                                   
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----------------------------------------------------------------

ADKKKLFKKEKHIRFTVVDSGIGMSH------QKLQKLKR-------MLFKKEIFNIQNS--SGLGLTMCYSLIKQIGCQHTHLEIQSEENIGTKFSFTI
           |.|.|| |.|.|..       ......         .              .||||..|. ...| | .   ....||.. ||.|.||.
----------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD----SR-RKYGGGLTGLGLYICRRIVEQHGGT---IWVESEPGGGTTFTFTL

QQF
   
PLE

Kinase 3312.AA HATPase_c 779-966 13 2.4e-12 48.26 SMART 1-130 (130) Show / Hide
Range on Protein: 779-966
Range on HMM: 1-130/130
Sequence Identity: 13% (29 aa)

HDQRRLLQILVNLISNSLKFTFK--------------GKIELIIDTPSDENNINLGSMHMFQNNQISTGRYSNSPSSNKNKQLDTRSLQSNLLFKNCKNQ
 |..|| |.| ||..|..|.| .              |.|.. ..                                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

EIIQSNNNLIDKLADKKKLFKKEKHIRFTVVDSGIGMSH------QKLQKLKRMLFKKE----------IFNIQNS--SGLGLTMCYSLIKQIGCQHTHL
                          |.|| |.|.|..       ......    .. .                   .||||. | ....| | .   .
--------------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT---I

EIQSEENIGTKFSFTIQQFY
...      |.|.||.    
WVE------TTFTFTLPLER

REC 3312.AA REC 1518-1638 21 2.1e-21 78.33 SMART 1-150 (150) Show / Hide
Range on Protein: 1518-1638
Range on HMM: 1-150/150
Sequence Identity: 21% (35 aa)

KHVLVVDDTI---YNIISLKI------FFRNVQNLN--------IEEAYNGR-------DALQKYQENAINGI--------FYDYIFMDIEMP-------
...|.|||       |  .        ..   ..          ..|| .|.       .||.. ||.  ...         .| |.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGLECIKHIREFETANSLKKSIIITVTAYEREQQEVILAGANALIAKPIQKDKFLQTL
 |||.| ...||         . |..|  . |   .. . |||.. | ||.. . .|...
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 3312.AA Response_reg 1520-1639 33 2.1e-16 61.33 Pfam 1-115 (115) Show / Hide
Range on Protein: 1520-1639
Range on HMM: 1-115/115
Sequence Identity: 33% (41 aa)

VLVVDDTIYNIISLKIFFRNVQNL-NIEEAYNGRDALQKYQENAINGIFYDYIFMDIEMPIMDGLECIKHI-REFETANSLKKSIIITVTAYER--EQQE
||.|||   .   |. ....   . ...||..|..||.. ||.      .| |.|||.|| ||||| .. | |. .   .     || .||..     .|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-----PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDEDDAVE

VILAGANALIAKPIQKDKFLQTLR
.. ||||  |.||. .|. .. .|
ALQAGANDYITKPFDPDELHAAIR