Gene 5266 (Tetrahymena)

5266

Species: Tetrahymena
Alias: 5266, 36.m00230, 3703.m00092, PreTt05266, TTHERM_00348540, 484
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
5266.AA Protein None 1629 None Fasta, JSON
5266.kin_dom Protein Kinase Domain None 115 None Fasta, JSON
5266.NA RNA None 4890 None Fasta, JSON

Protein domain

Protein domains of 5266.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 5266.AA HisKA 486-552 27 1.2e-15 57.54 Pfam 1-69 (69) Show / Hide 
Range on Protein: 486-552
Range on HMM: 1-69/69
Sequence Identity: 27% (19 aa)

YKDQMLATVTHDLKTPLNGIIIMIKTLIESSQHTEEE--MKVMKMVLQNANLLLSMIQDILDYSQIKRN
 | |.||.. |.|.|||..|. ....| ...  ..|.   .  . ... |. ....|.|.||.|.|  .
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 5266.AA HisKA 486-552 21 1.4e-15 59.03 SMART 1-89 (89) Show / Hide 
Range on Protein: 486-552
Range on HMM: 1-89/89
Sequence Identity: 21% (19 aa)

YKDQMLATVTHDLKTPLNGIIIMIKTLIE---------SSQHTEEE-------------MKVMKMVLQNANLLLSMIQDILDYSQIKRN
 |.|.||.. |.|.|||..|. ....| .         ..  ..|.              .. . ... |. ....|.|.||.|.|  .
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 5266.AA HisK 825-939 38 2.5e-61 210.08 In-house 1-164 (164) Show / Hide 
Range on Protein: 825-939
Range on HMM: 1-164/164
Sequence Identity: 38% (63 aa)

SDKRRIKQILINLVGNALKFTERG------SISIEYNVISDR-------------------------NLVEIVVRDTGVGISESLQPKLFKVYS------
||..|||||||||..||||||. |      .|.|... |..                          ||..| | |||.|..|..| |.|| ..      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFDHNNG-SNRHGVGLGLAICKKLAQQLGPE------KNIKLTSTKGDGSSFSFLIYQD
     ||.|.|. .|.||.||||.||..||..||||      ..|.. |..| ||.|||.||..
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 5266.AA HATPase_c 825-940 23 1.4e-27 98.85 SMART 1-130 (130) Show / Hide 
Range on Protein: 825-940
Range on HMM: 1-130/130
Sequence Identity: 23% (34 aa)

SDKRRIKQILINLVGNALKFTER--------------GSISIEYNVISDRNLVEIVVRDTGVGISE------SLQPKLFKVYSTFDH--------NNGSN
 | .|..|.|.||..||.|.|.               | |... .        .|.|.|.|.||..       ..|..|  . ..|         .. ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRK

RHG--VGLGLAICKKLAQQLGPEKNIKLTSTKGDGSSFSFLIYQDI
. |   ||||.|||....|.| .  |...      . |.| .   .
YGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
Kinase 5266.AA HATPase_c 825-939 29 2.3e-27 97.44 Pfam 1-120 (120) Show / Hide 
Range on Protein: 825-939
Range on HMM: 1-120/120
Sequence Identity: 29% (37 aa)

SDKRRIKQILINLVGNALKFTER-GSISIEYNVISDRNLVEIVVRDTGVGISE------SLQPKLFKVYSTFDH-NNGSNRHG--VGLGLAICKKLAQQL
 | .|..|.. |||.||.|.|.  | |...       . |.|.|.|.|.||..       ..|..|  . ..|   . ... |   ||||.||.....|.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQH

GPEKNIKLTSTKGDGSSFSFLIYQD
| .  | ..|. | |. |.| .  .
GGT--IWVESEPGGGTTFTFTLPLE
REC 5266.AA REC 1320-1625 12 1.3e-20 75.71 SMART 1-150 (150) Show / Hide 
Range on Protein: 1320-1625
Range on HMM: 1-150/150
Sequence Identity: 12% (43 aa)

VNILIVDDT----TFNLIALK------AMLKKVRNI------NLIVDAYNGK-------EALEKFKQN-------------KFDLVLMDINMP-------
 .||||||       .. .|.      ..|.|          . .. | .|.       ||||.....             ..||..|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGQESMRHMRSYEKEQYYKSQKRYNSKHSSYYSPLQKLNSSRNEEGTFTQYQQSIIYGEVSDNQIAETNDDFTSKYKKVINLCQNQDQQNQIGISEIQ
 ||| |  |..|                                                                                        
GMDGIELCRRIR----------------------------------------------------------------------------------------

NRNIQDQNAQKQENAQTNKQPTFQGLSPAYSNSPLNRKGQILKQGQRQSRRIKTATIEESPRAIFENGSPGLNQQLMLQKQIQGHIQTSSQSFSRNNLNS
                                                                                                    
----------------------------------------------------------------------------------------------------

GNNSKVYWNAIIFAVTAYDQQQDIQKYLQAGANAHISKPIKLENLFSVI
           | ..||.|. .|... |.|||.. |.||...| |  .|
----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 5266.AA Response_reg 1322-1388 39 6.9e-15 55.9 Pfam 1-68 (115) Show / Hide 
Range on Protein: 1322-1388
Range on HMM: 1-68/115
Sequence Identity: 39% (27 aa)

ILIVDDTTFNLIALKAMLKKVRNINLIVDAYNGKEALEKFKQNKFDLVLMDINMPIMDGQESMRHM-R
.|||||   .. .|. .|..   .. .  |..|.||||.......||..|||||| ||| |  | . |
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRR
Response_reg 5266.AA Response_reg 1590-1626 37 8.6e-07 26.9 Pfam 79-115 (115) Show / Hide 
Range on Protein: 1590-1626
Range on HMM: 79-115/115
Sequence Identity: 37% (14 aa)

AVTAYDQQQDIQKYLQAGANAHISKPIKLENLFSVIN
..||... .|....|||||| .|.||.... |   |.
MCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR