Gene 6037 (Tetrahymena)

6037

Species: Tetrahymena
Alias: 1075, TTHERM_00335940, PreTt06037, 3689.m00071, 34.m00274, 6037
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
6037.AA Protein None 1157 None Fasta, JSON
6037.kin_dom Protein Kinase Domain None 117 None Fasta, JSON
6037.NA RNA None 3474 None Fasta, JSON

Protein domain

Protein domains of 6037.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 6037.AA HisKA 139-206 20 2.5e-09 35.47 Pfam 1-69 (69) Show / Hide 
Range on Protein: 139-206
Range on HMM: 1-69/69
Sequence Identity: 20% (14 aa)

YQKRMMSTITHNLKTPLNGIILLLQSLIQ-QKDQIPEELYYQIIDIYTNSELLLCMINDVIDYSKIQSD
 ........ | |.|||..|..... |   ..   ....   .  |.  .. .. .|||. |.|.|.. 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 6037.AA HisKA 139-206 16 2.8e-09 38.06 SMART 1-89 (89) Show / Hide 
Range on Protein: 139-206
Range on HMM: 1-89/89
Sequence Identity: 16% (15 aa)

YQKRMMSTITHNLKTPLNGIILLLQSLIQ--------QKDQIPEEL-------------YYQIIDIYTNSELLLCMINDVIDYSKIQSD
 . ...... | |.|||..|..... |          ...  ..|                 .  |.  .. .. .|||. |.|.|.. 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 6037.AA HisK 253-369 30 1.6e-49 170.88 In-house 1-164 (164) Show / Hide 
Range on Protein: 253-369
Range on HMM: 1-164/164
Sequence Identity: 30% (50 aa)

TDYERLKQILVNLTGNALKFTFEG------YIKIVIKESNLD------------------------SNIVEIQVTDTGNGISKHIKQSLLQKKI------
.|. |.||||.|| .||||||..|      |||| ....| .                        .|...|.| ||| |....... . ..        
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TDNHKHKLDKQSGSGIGLNICQQLVEKLGPH------SKLFIQSVEKQGTKISFYLYKN
     |.||..|...|.| |.||.||..|...|||.       .. .|| ...|.. |||.|.|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 6037.AA HATPase_c 253-369 26 1.3e-21 77.46 Pfam 1-120 (120) Show / Hide 
Range on Protein: 253-369
Range on HMM: 1-120/120
Sequence Identity: 26% (35 aa)

TDYERLKQILVNLTGNALKFTFE-GYIKIVIKESNLDSNIVEIQVTDTGNGISK------HIKQSLLQ-------KKITDNHKHKLDKQSG--SGIGLNI
.| .||.|.. || .||.|.| | | |.. ... .   . |.|.|.|.| ||..      .  . ...               .  .| .|  .|.|| |
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-------SR-RKYGGGLTGLGLYI

CQQLVEKLGPHSKLFIQSVEKQGTKISFYLYKN
|...||..| .  . ..| ...||...|.| . 
CRRIVEQHGGT--IWVESEPGGGTTFTFTLPLE
Kinase 6037.AA HATPase_c 253-370 22 3.3e-19 71.04 SMART 1-130 (130) Show / Hide 
Range on Protein: 253-370
Range on HMM: 1-130/130
Sequence Identity: 22% (33 aa)

TDYERLKQILVNLTGNALKFTFE--------------GYIKIVIKESNLDSNIVEIQVTDTGNGISK------HIKQSLLQKKITDNH-------KHKLD
.| .||.|.| || .||.|.| |              | |.. ..         .|.|.|.| ||..      .. . ....  .          . .  
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

KQSG--SGIGLNICQQLVEKLGPHSKLFIQSVEKQGTKISFYLYKNF
| .|  .|.|| ||...||..| . ..         |...|.| .  
KYGGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER
REC 6037.AA REC 1031-1147 26 2.4e-34 121.35 SMART 1-150 (150) Show / Hide 
Range on Protein: 1031-1147
Range on HMM: 1-150/150
Sequence Identity: 26% (41 aa)

KKILIVDDT----MFNVIALK------ALLMNITKN-----SIVIEEAFNGR-------QAMQKVLQSQ-----------ELFDLIFMDVNMP-------
..||||||       .  .|.      .||.           .|..|| .|.       .|.... . .           | .|||.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMDGLQATENIKQIDRNNKIIIVTAFSDETNRSECISIGADGFLTKPVKIKDLATQI
 |||..... |.      .||..||..||  | ...  |||...|||.....|   |
GMDGIELCRRIR------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 6037.AA Response_reg 1033-1148 34 1.3e-28 105.03 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1033-1148
Range on HMM: 1-115/115
Sequence Identity: 34% (41 aa)

ILIVDDTMFNVIALKALLMNITKNSI-VIEEAFNGRQAMQKVLQSQELFDLIFMDVNMPVMDGLQATENI-KQID-RNNKIIIVTAFSDETNRSECISIG
.|||||   .  .|. .| .  |  . |..|| .|..|.... . .  .|||.||.||| ||||.... | .| .  . .||..||..||  . |..  |
VLIVDDHPLMREGLRQILEQ--KEGYEVVAEADDGEEALEWWQEHH--PDLIIMDINMPGMDGLELCRRIRRQHPHPQTPIIMCTAHGDEDDAVEALQAG

ADGFLTKPVKIKDLATQIQ
|....|||... .| . |.
ANDYITKPFDPDELHAAIR