6570

Species: Tetrahymena
Alias: 6570, PreTt06570, 89.m00164, TTHERM_00630570, 111, 3831.m01465
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
6570.AA Protein None 1055 None Fasta, JSON
6570.kin_dom Protein Kinase Domain None 122 None Fasta, JSON
6570.NA RNA None 3168 None Fasta, JSON

Protein domain

Protein domains of 6570.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 6570.AA HisKA 265-335 34 5.1e-10 37.91 Pfam 1-69 (69) Show / Hide
Range on Protein: 265-335
Range on HMM: 1-69/69
Sequence Identity: 34% (25 aa)

EKMKIFATLSHELRTPLNCSISMLEVLKD--ELYQEQNNQYCIEEYIVPALFSNKLLLNQINDILDFVQMDCG
.| . .|..||||||||.  . ..|.|.|  .|  ||.    ..||.  .. . . ....|||.||| ... |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQM----RREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 6570.AA HisKA 265-335 26 1.1e-09 39.39 SMART 1-89 (89) Show / Hide
Range on Protein: 265-335
Range on HMM: 1-89/89
Sequence Identity: 26% (24 aa)

EKMKIFATLSHELRTPLNCSISMLEVLKDELY-----------QEQNNQYC-------IEEYIVPALFSNKLLLNQINDILDFVQMDCG
.| . .|..||||||||.  . ..|.|.|..|            ||.  .        ..||.  .. . . ....|||.||. ... |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 6570.AA HisK 382-503 36 7.8e-58 198.46 In-house 1-164 (164) Show / Hide
Range on Protein: 382-503
Range on HMM: 1-164/164
Sequence Identity: 36% (60 aa)

SDPNRIRQILLNFLSNSLKFTKSG------HIELGLVLFS--------------------------KNIYQLYVKDSGIGITQENQKKIFNFCNKIK---
||||||.|||.|..||.||||. |      .|.. . ...                          ||..| .|.|.|.|...|.|||||.....|.   
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----YQNKEEEQLNNQGCGLGLTISNSLAKGLVNDVN--FKGGITVESEYGKGSKFSILVEDF
     ..|......| .||||||||.|.||||| .. |   ..||.|.||.||||.||......
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 6570.AA HATPase_c 382-503 23 1.7e-17 63.13 Pfam 1-120 (120) Show / Hide
Range on Protein: 382-503
Range on HMM: 1-120/120
Sequence Identity: 23% (33 aa)

SDPNRIRQILLNFLSNSLKFTKS-GHIELGLVLFSKNIYQLYVKDSGIGITQ------ENQKKIFN-------FCNKIKYQNKEEEQLNNQG--CGLGLT
 ||.|..|...|...|..|.|.. |||.. .     .  .. |.|.|.||.       |.. .||                       . .|   ||||.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD----------SR-RKYGGGLTGLGLY

ISNSLAKGLVNDVNFKGGITVESEYGKGSKFSILVEDF
|.. ... .  .      |.|||| |.|..|.. .   
ICRRIVEQHGGT------IWVESEPGGGTTFTFTLPLE

Kinase 6570.AA HATPase_c 382-504 18 7.9e-15 56.5 SMART 1-130 (130) Show / Hide
Range on Protein: 382-504
Range on HMM: 1-130/130
Sequence Identity: 18% (29 aa)

SDPNRIRQILLNFLSNSLKFTKS--------------GHIELGLVLFSKNIYQLYVKDSGIGITQ------ENQKKIFNFCNKIKYQNKE--------EE
 ||.|.||.|.| |.|..|.|..              |.|.. .        .. |.|.|.||..      | ...||       |. ..        . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIF----EPFYRTDDSPSRMCPDSR

QLNNQG--CGLGLTISNSLAKGLVNDVNFKGGITVESEYGKGSKFSILVEDFN
  . .|   ||||.|...... .  .. .             ..|.. .    
SRKYGGGLTGLGLSICKRIVEQHGGTIWVE------------TTFTFTLPLER

REC 6570.AA REC 886-1001 18 2.2e-17 64.98 SMART 1-150 (150) Show / Hide
Range on Protein: 886-1001
Range on HMM: 1-150/150
Sequence Identity: 18% (28 aa)

PQIMVVDDN----QFNLYAMQ------KIIQQFQFE--------IITFSEGD-------QAIQFVKSEF-------FKNCCTSPRIIFMDIEMP------
. |..|||.    . .. ...      .. ..  .|        ....  |.       .|.. ....             . | .|.|||.||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-VKNGYETVVQYNNIPIIIACTSYVGQEDCKKCIESGMSDFINKPLLKTGFQSII
   .|.|.. .      ||..|.. . ||  ...|.|. |.| ||     ..  |
GGMDGIELCRRIR---PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 6570.AA Response_reg 888-991 23 8.4e-13 48.43 Pfam 1-104 (115) Show / Hide
Range on Protein: 888-991
Range on HMM: 1-104/115
Sequence Identity: 23% (26 aa)

IMVVDDNQFNLYAMQKIIQ-QFQF-EIITFSEGDQAIQFVKSEFFKNCCTSPRIIFMDIEMPVKNGYETVVQY-NNIP----IIIACTSYVGQEDCKKCI
...|||.. .. ....|.. . .. .. ... | .|.. .. .        | .|.|||.||  .|.|.  .   . |     ||.||..   .|  ...
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQTPIIMCTAHGDEDDAVEAL

ESGMSDFINKP
. |. |.| ||
QAGANDYITKP