6877

Species: Tetrahymena
Alias: 3715.m00022, PreTt06877, 401, 6877, TTHERM_00497110, 62.m00161
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
6877.AA Protein None 1202 None Fasta, JSON
6877.kin_dom Protein Kinase Domain None 141 None Fasta, JSON
6877.NA RNA None 3609 None Fasta, JSON

Protein domain

Protein domains of 6877.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 6877.AA HisK 653-793 25 2.3e-39 137.07 In-house 1-164 (164) Show / Hide
Range on Protein: 653-793
Range on HMM: 1-164/164
Sequence Identity: 25% (46 aa)

IDPIRFKQILINLLQNSLKFSDQN---TQIDIYLQHPSDD--------------------------NENLQVIVQDQGIGMDEEEQKALTRLLQEG----
 || |.|||||||..|.||| ...    |. | ..   ..                          ....|. ||| |.||.||.|| .  .....    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

------VSENKISHKTSGYGFGLTVSNKIAVKLNEEIICEKTKQPDSKKQKKLNQQNQQGLYFESIPKKGSKFWFFINVE
       ..........| |.|||..|..| .| .|..     |         |  ...|....| ..|||.|.|.|.  
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHN-----Q---------N--GNRGIQVQSEVGKGSTFSFYIYNN

Kinase 6877.AA HATPase_c 653-794 16 2.2e-23 84.92 SMART 1-130 (130) Show / Hide
Range on Protein: 653-794
Range on HMM: 1-130/130
Sequence Identity: 16% (28 aa)

IDPIRFKQILINLLQNSLKFSDQ-------------NTQIDIYLQHPSDDNENLQVIVQDQGIGMDE----EEQKALTRLLQEGVSENK---------IS
.||.|..|.|.|||.|..|....             ...|.. .          .. |.| |.|...     . . . |... ...  .          |
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSI-EDIPRIFEPFYRTDDSPSRMCPDSRS

HKTSG--YGFGLTVSNKIAVKLNEEIICEKTKQPDSKKQKKLNQQNQQGLYFESIPKKGSKFWFFINVEK
.|..|   | ||.....|. ... .| .|                              ..|.| . .|.
RKYGGGLTGLGLSICKRIVEQHGGTIWVE------------------------------TTFTFTLPLER

Kinase 6877.AA HATPase_c 653-793 17 1e-20 74.31 Pfam 1-120 (120) Show / Hide
Range on Protein: 653-793
Range on HMM: 1-120/120
Sequence Identity: 17% (26 aa)

IDPIRFKQILINLLQNSLKFSDQNTQIDIYLQHPSDDNENLQVIVQDQGIGMDE---EEQKALTRLLQEGVSENK--ISHKTSG--YGFGLTVSNKIAVK
 ||.|..|.. ||. |..|.. ....|.. . .     ..... |.| |.|...      . . |... ...  .     |..|   |.||.....|. .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ

LNEEIICEKTKQPDSKKQKKLNQQNQQGLYFESIPKKGSKFWFFINVE
.. .| .| .                         ..|..|.| . .|
HGGTIWVESEP------------------------GGGTTFTFTLPLE

REC 6877.AA REC 1052-1195 18 6.5e-12 46.83 SMART 1-150 (150) Show / Hide
Range on Protein: 1052-1195
Range on HMM: 1-150/150
Sequence Identity: 18% (31 aa)

PYILIVDDCQTNHYCLMLYLE------KIFKISKKQ--------ILQAYNGV-------QGYEKFLQYQSKVQQICQIFIQEFNLQNKGKIKLIFMDLNM
. ||||||       ..  |.      ....    .        . .| .|        .. |.. . ..|        ...  . ..... ||.||..|
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKK-------EDATTD-QSEPPDLIIMDIMM

P-------IQNGKESTQQIREYEKENNLKSSAIVAYTAYSDPTTENECLTECGFNYFLAKPLTDANKLREIL
|         .| | ...||            |.. ||..|. .  ..| | | . .. || ..   |.. .
PGDPFEDGGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRAL-EAGADDYITKPFDPE-ELLARI

Response_reg 6877.AA Response_reg 1123-1196 30 1.3e-09 36.95 Pfam 47-115 (115) Show / Hide
Range on Protein: 1123-1196
Range on HMM: 47-115/115
Sequence Identity: 30% (23 aa)

LIFMDLNMPIQNGKESTQQI-REYEKENNLKSSAIVAYTAYSDPTTENECLTECGFNYFLAKPLTDANKLREILQ
||.||.|||  .| | ...| |. . . .     |.. ||..|. .  |.| . | |....||  | ..|.....
LIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDEDDAVEAL-QAGANDYITKPF-DPDELHAAIR