7983

Species: Tetrahymena
Alias: PreTt07983, 63.m00161, 7983, 3716.m00015, 398, TTHERM_00499400
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
7983.AA Protein None 1210 None Fasta, JSON
7983.kin_dom Protein Kinase Domain None 121 None Fasta, JSON
7983.NA RNA None 3633 None Fasta, JSON

Protein domain

Protein domains of 7983.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 7983.AA HisKA 524-592 31 1e-11 43.79 Pfam 1-69 (69) Show / Hide
Range on Protein: 524-592
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

EKMKIFASLSHELRTPLNCSISMLEVLRD-EIQSSNPTYIEEYLNPALFSNKLLLNQINDILDFVQLDSD
.| . .|..||||||||.  . ..|.|.| . ...    ..|||. .. . . ....|||.||| .... 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQM-RREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 7983.AA HisKA 524-592 24 1.9e-10 41.92 SMART 1-89 (89) Show / Hide
Range on Protein: 524-592
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

EKMKIFASLSHELRTPLNCSISMLEVLRD--------EIQSSNPTYI------------EEYLNPALFSNKLLLNQINDILDFVQLDSD
.| . .|..||||||||.  . ..|.|.|        . .  .|  .            .|||. .. . . ....|||.||. .... 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 7983.AA HisK 601-721 35 3.5e-58 199.59 In-house 1-164 (164) Show / Hide
Range on Protein: 601-721
Range on HMM: 1-164/164
Sequence Identity: 35% (58 aa)

SDPNRIRQIVLNFLSNSLKFTKQG------YIEIGFVQIS--------------------------YGLYKLYVKDTGIGITEENLQKLFTFCTKI----
||||||.||..|..||.||||..|      ||.| . ||.                           .|.. .|.|||.|..||...|.| .. .|    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----KYDKQDEGLNNQGCGLGLTISNSIAQGLVNRQN--QEGGITVESVYGQGSTFSIIIQDM
     ....|.. .| .||||||||.|..|.|| ...|  . .||.|.| .|.|||||. |.. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 7983.AA HATPase_c 601-721 24 1.2e-18 67.08 Pfam 1-120 (120) Show / Hide
Range on Protein: 601-721
Range on HMM: 1-120/120
Sequence Identity: 24% (33 aa)

SDPNRIRQIVLNFLSNSLKFTKQ-GYIEIGFVQISYGLYKLYVKDTGIGITE------ENLQKLFT-------FCTKIKYDKQDEGLNNQG--CGLGLTI
 ||.|..|.|.|...|..|.|.. | |..   .   .   . |.|.|.||..      |.....|                      . .|   ||||.|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---------SR-RKYGGGLTGLGLYI

SNSIAQGLVNRQNQEGGITVESVYGQGSTFSIIIQDM
.. |.. .  .      |.|||  |.|.||.. .   
CRRIVEQHGGT------IWVESEPGGGTTFTFTLPLE

Kinase 7983.AA HATPase_c 601-722 20 7.2e-16 59.97 SMART 1-130 (130) Show / Hide
Range on Protein: 601-722
Range on HMM: 1-130/130
Sequence Identity: 20% (32 aa)

SDPNRIRQIVLNFLSNSLKFTKQ--------------GYIEIGFVQISYGLYKLYVKDTGIGITEENLQKLFTFCTKIKYDKQDEGL-------------
 ||.|.||...| |.|..|.|..              | |..           . |.|.|.||..| . |         .. .|                
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMH-K---------SI-EDIPRIFEPFYRTDDSPS

---------NNQG--CGLGLTISNSIAQGLVNRQNQEGGITVESVYGQGSTFSIIIQDMN
         . .|   ||||.|...|.. .  .      |.||      .||.. .    
RMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER

REC 7983.AA REC 1078-1202 20 6.7e-23 83.32 SMART 1-150 (150) Show / Hide
Range on Protein: 1078-1202
Range on HMM: 1-150/150
Sequence Identity: 20% (33 aa)

PQIVIVDDN----QFNLYALS------KIIQQYSFT--------LQQICDGA-------QAIETLKNLY-------FKNCCLAPKIIFLDIEMP------
. | ||||.    . .. .|.      .. ..  ..          .  ||.       .|.| |...               | .|..||.||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-FKNGYEVAKELNQFYESVNFQYPPIIIACTAYVGQEDRQKAIDSGMDDFINKPILKSGFQQLL
   .|.|.....              ||..||. . |||..|...|.||.| ||.    ... .
GGMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 7983.AA Response_reg 1080-1193 26 2.1e-17 64.9 Pfam 1-105 (115) Show / Hide
Range on Protein: 1080-1193
Range on HMM: 1-105/115
Sequence Identity: 26% (31 aa)

IVIVDDNQFNLYALSKIIQ-QYSF-TLQQICDGAQAIETLKNLYFKNCCLAPKIIFLDIEMPFKNGYEVAKEL-NQFYESVNFQYPPIIIACTAYVGQED
. ||||.. .. .| .|.. .. .       ||..|.| ....        | .|..||.||  .|.|.....  | . . .    . ||.|||.   .|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDEDD

RQKAIDSGMDDFINKPI
...|.. |..|.| ||.
AVEALQAGANDYITKPF