11147

Species: Tetrahymena
Alias: 11147, TTHERM_00046680, PreTt11147, 3.m01919, 1116, 3824.m02908
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO1

Sequence

Name Sequence Type Origin Length Description Download
11147.AA Protein None 638 None Fasta, JSON
11147.kin_dom Protein Kinase Domain None 190 None Fasta, JSON
11147.NA RNA None 1917 None Fasta, JSON

Protein domain

Protein domains of 11147.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11147.AA RIO1 160-382 76 2.1e-194 652.12 In-house 1-225 (225) Show / Hide
Range on Protein: 160-382
Range on HMM: 1-225/225
Sequence Identity: 76% (172 aa)

QVLDPRTRVILVKLLNKKIINEINGCLSTGKEANVYHASSSNGK--EYAIKIYKTSILVFKDREKYVAGEFRFRKGHCKSNPRKMIKLWAEKEIRNLKRI
||.|||||.|| |.| . || |||||.|||||.||||||..|||  |||||||||||||||||||||.||||||.||||.|||||||.|||||.||||||
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI

YQSSIPCPEPLIVKSNVLMMEFIGKDGKAAPRLKDAENIELEQYSKIYLQLLRDMRTLYQDCRLVHGDLSEYNLLYYNEKLYMIDVSQSIEHDHAHSLEF
|||.||||||..|||||||||||||||.|||||||....|..||...|.|....||..||||||||.||||||.||.|.||||||||||.||||.|||||
YQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEF

LRRDIVNVNMYFKKKNVITFSLRDI
||.|..||||||.|.|||.|..|||
LRMDCKNVNMYFMKHNVIIFPVRDI

Kinase 11147.AA RIO 158-385 44 1.7e-154 519.55 In-house 1-247 (276) Show / Hide
Range on Protein: 158-385
Range on HMM: 1-247/276
Sequence Identity: 44% (111 aa)

VEQVLDPRTRVILVKLLNKKIINEINGCLSTGKEANVYHASSSNGK-----------EYAIKIYKTSILVFKDREKYVAGEFRFRKGHCKSNPRKMIKLW
.||..||.|| |. |..|. .. ....| ..|||...||.|..||.           |.||||..|....||||.||..|||.|...|||.|.|.|..||
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AEKEIRNLKRIYQSSIPCPEPLIVKSNVLMMEFIGKDGKAAPRLKDAENIELEQYSKIYLQLLRDMRTLYQDCRLVHGDLSEYNLLYYNEKL-------Y
||||.||.||.|||..|||||...|..||.||||..|...||........|.|.....|.|....||.|||.|||||.|..|.|......|.       |
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

MIDVSQSIEHDHAHSLEFLRRDIVNVNMYFKKKNV-ITFSLRDIFDF
|||..|..||||.|.|...|||...|||.|.|..| ..|..|..|||
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDF

RIO 11147.AA RIO 151-388 50 1e-131 444.77 SMART 1-253 (253) Show / Hide
Range on Protein: 151-388
Range on HMM: 1-253/253
Sequence Identity: 50% (128 aa)

DKSDRATVEQVLDPRTRVILVKLLNKKIINEIN--GCLSTGKEANVYHASS----SNGKEYAIKIYKTSILVFKDREKYVAGEFRFRKGHCKSNPRKMIK
|| |.||.|.|.||||| .| |..|...| |||  ||.|||||||||||..    .||.|.|.|||.||...||....|. |.|||..| ...|.|||..
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

LWAEKEIRNLKRIYQSSIPCPEPLIVKSNVLMMEFIGKDGKAAPRLKDAENIELEQYS--KIYLQLLRDMRTLYQDCRLVHGDLSEYNLLYY------NE
|||||| |||.|.|.. .|||.|  .. .|| |||||.||..||||||.|..| |  .  ..| |....|| .|. |.|||.||||||.||       ..
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

KLYMIDVSQSIEHDHAHSLEFLRRDIVNVNMYFKKKNVITFS-LRDIFDFITD
|...||.|||.|.|| ..||||.||| |.. .|..|.| ...  |.||..||.
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG

Kinase 11147.AA RIO1 193-382 49 1.3e-108 339.14 Pfam 1-200 (200) Show / Hide
Range on Protein: 193-382
Range on HMM: 1-200/200
Sequence Identity: 49% (98 aa)

NVYHASS-SNGK-EYAIKIYKTSILVFKDREKYVAGEFRFRKGHCKSNPRKMIKLWAEKEIRNLKRIYQSSIPCPEPLIVKSNVLMMEFIG-KDGKAAPR
||||| | ..|| |.|.|||.|....||....|. ..|||| . ...|.|.|...||||| |||||.|.  .|||.|  .. .|| ||||| ||| .|||
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

LKDAE-NIE--LEQYSKIYLQLLR-DMRTLYQDCRLVHGDLSEYNLLYYNE-KLYMIDVSQSIEHDHAHSLEFLRRDIVNVNMYFKKKNVI--TFSLRDI
|||.| ..|   |. . || ...|  || .||.|.||||||||||.|.. . |...||..|. |||| |.||||.||. |.. .|..| |   ... |.|
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI





Kinase 11147.AA RIO3 155-397 41 7.2e-71 238.1 In-house 1-254 (254) Show / Hide
Range on Protein: 155-397
Range on HMM: 1-254/254
Sequence Identity: 41% (107 aa)

RATVEQVLDPRTRVILVKLLNKKIINEINGCLSTGKEANVYHAS----------SSNGK-EYAIKIYKTSILVFKDREKYVAGEFRFRKGHCKSNPRKMI
 .| |. .||.||... |..|  ... | ||..||||. |.||           |     . |||..||..  ||.|.||.  .|||.    | ||||. 
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

KLWAEKEIRNLKRIYQSSIPCPEPLIVKSNVLMMEFIGKDGKAAPRLKDAENIELEQYSKIYLQLLRDMRTLYQDCRLVHGDLSEYNLLYYNEKLYMIDV
..|||||. || |. .. ||||  ...|  .|.| |||.|   ||.||.   .. |.  . | | |  || || .| ||| ||||||.|..  |...|||
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVK-LNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDV

SQSIEHDHAHSLEFLRRDIVNVNMYFKKKNVI-TFSLRDIFDFITDINIVPGTEA
|||.|  | | |||| ||  ||  .|.|  |  ..| |..|. .. .||    ||
SQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA

Kinase 11147.AA Ciliate-C1 181-219 26 2e-05 9.46 In-house 2-46 (328) Show / Hide
Range on Protein: 181-219
Range on HMM: 2-46/328
Sequence Identity: 26% (12 aa)

EINGCLSTGKEANVYHASSSNGK-EYAIKIYKT-----SILVFKD
.|   . .|. . |  ..  |..  ||.|. |        | |||
KIMKTIGHGYTCKVFYCKMPNNQKVYAVKQFKNEYTSQQQLTFKD

Kinase 11147.AA Jak 318-362 23 0.0008 9.59 In-house 136-186 (299) Show / Hide
Range on Protein: 318-362
Range on HMM: 136-186/299
Sequence Identity: 23% (12 aa)

DCRLVHGDLSEYNLLYYNEKLY------MIDVSQSIEHDHAHSLEFLRRDI
|.|..|||..  |.|. .|..        .......  |.....|.. ||.
DKRYIHGDVCARNILVDREGHWCCVKIPFFKLMDPWCSDKEYYREMMDRDE