Gene 13750 (Tetrahymena)

13750

Species: Tetrahymena
Alias: 868, TTHERM_00202780, PreTt13750, 13750, 17.m00357
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C1

Sequence

Name Sequence Type Origin Length Description Download
13750.AA Protein None 745 None Fasta, JSON
13750.kin_dom Protein Kinase Domain None 258 None Fasta, JSON
13750.NA RNA None 2238 None Fasta, JSON

Protein domain

Protein domains of 13750.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13750.AA Ciliate-A2 484-734 24 3.1e-111 375.87 In-house 1-272 (272) Show / Hide 
Range on Protein: 484-734
Range on HMM: 1-272/272
Sequence Identity: 24% (66 aa)

GDGCSSVVYLAKEMD----ELNNILSNNLIAIKKFKKRKEHHFESEHKILSLINGQHPNIIKIQS--INTSQMEIQSDYCPNGDLLDFVIK----RGALR
|.||...|.....||    |...|.....|.....|.......|..|....|.|..||||.|...  .......||...||...| |...|    .....
GQGCFGCVIFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIP

ESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASFN-PVVIDFAFAAFNKPNLTDFIGTDGYQAPEIILKYPYCGFA----------ADNFSLGVM
..|...|......|..||...|...|||.|.|||.|.... ....||..|....|....................|.|.|.          ........|
DHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQCFEMNGEQNKKQQIKQTFM

LFEMVMGKPPFQHAKLDQGLYKKFTQENVEYWEVFKKYQNPSDQLKDLINKLLESEPQNRISIDEVLQHPWM
......|....|....||. ..|.||.|...|.....|.|........|...|...|..|.|......|.|.
GDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH
Kinase 13750.AA CAMK 482-734 21 3.7e-79 254.57 In-house 1-425 (425) Show / Hide 
Range on Protein: 482-734
Range on HMM: 1-425/425
Sequence Identity: 21% (91 aa)

KIGDGCSSVVYLAKEMDELNNILS------NNLIAIKKFKKR-------------------------------KEHHFESEHKILSLING-----QHPNI
..| |  ..|.|...    ... .      .   |||  .|.                               ... ...| .|.....|     .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKIQSINTS---------------------QMEIQS---DYCPNG----DLLDFVIKR---------------GALRESQARFFFKGVSKAVQYLQQRNI
||.  .  .                     .| .     .||..|    ||.|.....               | . |..||..|. .  ||.|. ..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKLENILLDAS-----------------FNPVVIDFAFAAFNKPN--------------------------LTDFIGTDGYQA-PEIILK------
.|||||.|||||| .                 .|  .||| ||.. .|.                          ...| || .| | ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------YPYCGFAADNFSLGVMLFEMVMGKPPFQHAK------------LDQGLYKKFTQENVE-YWEV-------------------FKKYQNPSDQL
        ||.|...|  |.||.|. |. |.|||.. .             |. |..| .. . . ...                    | .  . |.. 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF-HH-FVSQEC

KDLINKLLESEPQNRISIDEVLQHPWM
||||.|.|. .|..|..|...|.||||
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 13750.AA Ciliate-C1 477-734 31 2.7e-72 186.88 In-house 1-328 (328) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-328/328
Sequence Identity: 31% (104 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNN-LIAIKKFK-----------------KRKEHHFESEHKIL-----SLINGQ-HPNIIKIQS-INTSQME
.|| ..|| |  . | ..|  .       |.   |.|.||                 .   || ||  ...     .|     ||||. . . |   |  
MKIMKTIGHGYTCKVFYCKMPN-------NQKVYAVKQFKNEYTSQQQLTFKDSSSPRENTHHSESCMQDHNNEIKHLQELKNHPNIVNMVQIIREIQYD

IQS-----------DYCPNGDLLDFVIKRGA-LRESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASFNPVVIDFAFAAF---------------
 .            .|| ||.| |.. . |    | .||. |.    ..||..| ||||||||.||||||  ||  . || || |               
KKNGQTYCFMCIVFEYCSNGELFDYIAHKGPLFNEELARYYFHQLINVIQYIHQNNICHRDLKPENILLDENFNLKIADFGFAQFLNSASSQNTLSKQKD

-NKPNLT------------------DFIGTDGYQAPEIILKYPYCGFAADNFSLGVMLFEMVMGKPPFQH-AKLDQGLYKKF-TQENVEYWEVF-KKY--
 .| |..                     ||.|| |||.. | .|||.. | |..|| || || | |||.  |      |. | .  .  ||.   |.|  
GEKMNHNTSSTECSDASSDESHWLYVCMGTEGYMAPELHEKQRYCGSKVDIFACGVILFCMVHGHPPFHKIAHPSDPYYRFFCENRYHQYWQCHQKNYGQ

-QNPSDQLKDLINKLLESEPQNRISIDEVLQHPWM
  . |. ..||||..|. .||.||.. |...|||.
HNFFSNEFMDLINQMLAYNPQKRITLQEIKCHPWY
S_TKc 13750.AA S_TKc 477-734 32 2e-71 244.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNNLIAIKKFKKRKEHHFESEHKILSLINGQHPNIIKIQSINT-SQMEIQSDYCPN--GDLLDFVIKRGA--
|.| |||| |  ..||.... .      .. . |||. |     |...| .||.    .||||.|.  .   . . .  .||..  |||.|.  |||   
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LRESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASFNPVVIDFAFAAFNKPNLTDFIGTDGYQAPEIILKYPYCGFAADNFSLGVMLFEMV
    . | .|||... . .|..|. ...|.||||| ||||||   .  ..|| .|..     | |.||  | |||..   .| ....|  |.|..|.||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

MGKPPFQHAKLDQGLYKKFTQENVEYWEVFKKYQNPSDQLKDLINKLLESEPQNRISIDEVLQ-------HPWM
 |.|||.    .| ..||                  |...||.|.|.|. .|..|... |.||       |||.
CGYPPFP---QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13750.AA Ciliate-E2 477-734 22 7.3e-69 235.09 In-house 1-365 (365) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-365/365
Sequence Identity: 22% (84 aa)

YKIERKIGDGCSSVVYLAKEMDELNNI-----------------LSNNLIAIKKFKKRKEHHFESEHKILSLIN--------------GQHPNIIKIQ--
||. .||| |. ..||..|   . ...                   ....|.| .||..  ....| .|.  ||               .||||||.   
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

--SINTSQMEIQSDYCPNGDLLDFVIKR-----------GALRESQARFFFKGVSK---------------AVQYLQQRN-ICHRDLKLENILLDASFNP
  ..... . .  .||  |||.|. ...           . . | ......| . .               |..|| ..| |.|||.|.||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

VVIDFAFAAFNKPNLTD----------------------------------FIGTDGYQAPEIILKYPY--------CGFAADNFSLGVMLFEMVMGKPP
 .||| .. .....  .                                  ..|| ||.||||. . .|         ....| .||||.|.||..||||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FQHAKLDQGLYKKFTQENVEYWEVFK------------KYQNPSDQLKDLINK----LLESEPQNRIS-IDEVLQHPWM
|         ...  | .... . ..            .... |.. ||||.|    .|. .|..||. ....|.|||.
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 13750.AA CAMKL 477-734 28 5.3e-66 209.58 In-house 1-297 (297) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-297/297
Sequence Identity: 28% (88 aa)

YKIERKIGDGCSSVVYLAKE-MDELNNILSNNLIAIKKFKKRKEHH------------------FESEHKILSLIN-GQHPNIIKIQSINT--------S
|.|.. .| |  ..| ||.  .        .   |||  .|.|                      . | .|....| |.||||||.  . .        .
YRIGKTLGKGSFGKVKLATHIRTT------GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETK

QMEIQSDYCPNGD--LLDFVIKRGA----LRESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASF--NPVVIDFAFAAF-----NKPN--LTDFI
.. .   ||..|.  |.|...|.|     . |..||..|. .  ||.|. ...|.|||.|.|||||| .   |  .||| |...     ..|.  |. | 
KIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFC

GTDGYQAPEIILK--YPYCGFAADNFSLGVMLFEMVMGKPPFQHAKL------DQGLYKKFTQENVEYWEVFKKYQNPSDQLKDLINKLLESEPQNRISI
|.  |.||||...   ||.|...|  |.||.|. || |. ||  . .      .. .... . .  .|. ....   .| ...||| |.|.  |  |..|
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYH---VS-DCRDLIRKMLQVNPEKRPTI

DEVLQHPWM
.....||||
HQIMNHPWM
Kinase 13750.AA Pkinase 477-734 26 1.9e-63 221.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNNLIAIKKFKKRKEHHFE-------SEHKILSLINGQHPNIIKIQSINT--SQMEIQSDYCPNG----DLL
|.|.|||| | ...||.... ..        . |.|..|||.|.. .       || .|.  .|  ||||...  . .  . . .  .||..|    || 
YHIGRKIGSGSFGCVYKCHHKGTGK------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

DFVI--KRGAL--RESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASFNP----VVIDFAFA----AFNKPNLTDFIGTDGYQAPEIILKYPYCG
|..   ..|..   | ...|... . ....|. ...|.|||||.||||.|   ..     ..|| .|      |.. .|.| || .| |||.|....| |
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

FAADNFSLGVMLFEMVMGKPPFQHA----KLDQGLYKKFTQENVEYWEVFKKYQNPS-----------------DQLKDLINKLLESEPQNRISIDEVLQ
 ..| .|.|..|.||. |.|||...    . .  ... .     .. . . .  ..|                 . .||.|...|.  |. |......||
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPWM
|||.
HPWF
Kinase 13750.AA Ciliate-E2-Unclassified 477-734 23 1.8e-59 203.9 In-house 1-352 (352) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-352/352
Sequence Identity: 23% (84 aa)

YKIERKIGDGCSSVVYLAKEMDELNNI-----LSNNLIAIKKFKKRKEHHFESEHKILSLIN---------------GQHPNIIKIQSINTSQME----I
||| ..|| |. ..||.... ..   .     .. . |  .| ...|.  .  | |..  ..                .||.....  . . | .    |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

QSDYCPNGDLLDFVIKRGA-----------------LRESQAR-----FFFKGVSKAVQYLQQRN-ICHRDLKLENILLDAS---FNPVVIDFAFAAFNK
  .||..|||...  ||.                  . | ||.     |.|. . .. .|| . | |.|||.|.||||.| .   ... .||| .. ...
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

PN------------------LTDFIGTDGYQ----APEIILKYPYCG---FAADNFSLGVMLFEMVMGKPPFQHAKLDQ---------------GLYKKF
 |                  ...|.|| .|.    |||.. .  | .   ...| .|||| |.||..|..||.  . .|                ||...
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

TQENVEYWEVFKKY--QNPSDQLKDLIN----KLLESEPQNRISIDEVLQHPWM
 | |... .  ..   .. |.. ||.||    |.|.  | .||.....|.|||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 13750.AA MARK 477-734 34 1.8e-54 176.56 In-house 1-262 (262) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-262/262
Sequence Identity: 34% (96 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNNLIAIK---KFKKRK---EHHFESEHKILSLINGQHPNIIKI-QSIN--TSQM--EIQSDYCPNGDLLDF
||. . || |  ..|.||       .....   |||   |||. .      ...| .|.....  ||||||  . |   |.|    .  .|...|.|.|.
YKMLKTIGHGSYAKVKLAC------HKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLD--HPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDY

VIKR--GALRESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASF--NPVVIDFAFAAFN--KPNLTDFIGTDGYQAPEIILKYPYCGFAADNFSL
....  | | |. || .|. .  ||.|. ..||.|||.|.||||.|.    |   ||| |..       |. | ||  | ||||.|| ||.|...|  ||
IKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSL

GVMLFEMVMGKPPFQ-HAKLDQGLYKKFTQENVEYWEVFKKYQNPSDQLKDLINKLLESEPQNRISIDEVLQHPWM
|| |. || |. ||    . .  |||| . .. ..          |.....||..||   |  |..|.|...||||
GVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH------VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 13750.AA ULK 477-734 24 7.3e-43 147.47 In-house 1-329 (329) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-329/329
Sequence Identity: 24% (82 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNNLIAIKKFK----KRKEHH---------FESEHKILSLINGQ------HPNIIKIQSINTSQ----MEIQ
| . ...| |   .|| .. ..      .| ..|.|.      ..|..          ...| ||.  .. .      ||||.|   .  ..      | 
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

SDYCPNGDLLDFVIKRGA----------LRESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASFNPV------------VIDFAFAAFNKPN---
 .||. ||| ..  |..           | |..|. |||    . ..|...|| |||.|..|||..  .               . || || .   .   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

---LTDFI------GTDGYQAPEIIL----KYPYCGFAADNFSLGVMLFEMVMGKPPFQHAKLDQGLYKKFTQENVEY---WE--------VFKKY---Q
   .. .       ||  | ||.|.     . ||. . .| .|||....||. |||||. |   . .|... |.....   |.         |.|.   .
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFY-AW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

NPSDQLKDLINKLLESEPQNRISIDEVLQHPWM
. |...|||| ..|. ..  |||..|...|||.
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 13750.AA Ciliate-E9 556-734 32 7.5e-43 134.67 In-house 91-298 (298) Show / Hide 
Range on Protein: 556-734
Range on HMM: 91-298/298
Sequence Identity: 32% (67 aa)

YCPNGDLLDFV-IKRGALRESQARFFFKGVSKAVQYLQQRN-ICHRDLKLENILLDASFNPVVIDFAFAAFNKPNLTDFI-----------GTDGYQAP-
|  || | |..    .   |  |...|| .  .. |..|   |||||||.||.|.|. .|  ..||.. |     .|  |           ||  |  | 
YANNGCLFDLISMHTEKFNENVAKYYFKQLIDSIEYMHQYQNICHRDLKPENMLIDKNYNMKICDFGMSAQCRNDKTQVIGNLQCQPKENHGTNQYNPPN

---EIILKYPYCGFAADNFSLGVMLFEMVMGKPPFQHAKLDQG-------LYKK---FTQENVE-YWEVFKKYQNP-SDQLKDLINKLLESEPQNRISID
   .  .   | | . | ||.|. || |||.  || | .            |     |  .| . .|. |.    | .   .|..|  |. .||||||| 
NQQQQYQGIKYNGQKFDIFSAGCILFMMVMNQYPFFHTNCYNDTTIDKIWQYYRIFFFCMDNCQNFWDQFIYNYRPEEQEFIDMMNWMLQQDPQNRISIQ

EVLQHPWM
|.  ||||
EIRMHPWM
Kinase 13750.AA ULK 477-734 24 2.8e-40 140.13 In-house 1-324 (324) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-324/324
Sequence Identity: 24% (80 aa)

YKIERKIGDGCSS-VVYLAKEMDELNNILSNNLIAIKKFKKRKEHHF-------------ESEHKILSLING-QHPN--IIKIQSINTSQ----MEIQSD
| . ...| |    .|| .. ..  .   .| ..|.|.  | |   .             ..| .|.  ..  .|||  |.|   .  ..      |  .
YCLNHCLGKGSFGVKVYKGRNKKTNT---QNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIME

YCPNGDLLDFVIKRGA---------LRESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASFNPV------------VIDFAFAAF-NKPNLTDFI
||. ||| ..  |..          | |..|. |||    . ..|...|| |||.|..|||.   .               . || || . ...|. ...
YCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQM

-----------GTDGYQAPEIIL----KYPYCGFAADNFSLGVMLFEMVMGKPPFQHAKLDQGLYKKFTQENVE-----------YWEVFKK--YQNP-S
           ||  | ||.|.     . ||. . .| .|||....||. ||.||. .   . .|..  |. ..            .  |.|  .... |
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFF-SW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

DQLKDLINKLLESEPQNRISIDEVLQHPWM
...|||| ..|. ..  |||..|...|||.
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 13750.AA TyrKc 477-734 20 1.1e-11 -33.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 477-734
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNNLIAIKKFKKRKEHHFESEHKILSLING-QHPNIIKIQSINT---------SQMEIQSDYCPNGDLLDFV
 . ..|.| |.  .||...              |.|. |. ..  | .| .|.. . | .||||...  . |          .. |   |.|.|||.|. 
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDAREDFMREARIMCKL-GGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

IKRGA-LRESQARFFFKGVSKAVQYLQQRNICHRDLKLENILLDASFNPVVIDFAFAAFNKPN-------LTDFI----GTDG-----YQAPEIILKYPY
 |..  |  ..   |   ...  .|| ..|. ||||   |.|... .   . ||  . . .          .       |...       ||| | .|  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

CGFAADNFSLGVMLFEMV-MGKPPFQHA----KLDQGLYKKFTQENVEYWEVFKKYQN--------PSDQLKDLINKLLESEPQNRISIDEVLQHPWM
. .. | .| ||...|.   |..|        . .| ..     |.|.  .  .. .|         .| . ... .  . .| .| .  |.  |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVI-----EYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 13750.AA APH 596-624 30 0.000272 15.52 Pfam 172-204 (248) Show / Hide 
Range on Protein: 596-624
Range on HMM: 172-204/248
Sequence Identity: 30% (10 aa)

ICHRDLKLENILLD--ASFNPV--VIDFAFAAF
.||.|... |...|  .  ..|  |||. .| .
WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACW
Kinase 13750.AA Pkinase_Tyr 556-601 34 0.000869 13.45 Pfam 88-137 (270) Show / Hide 
Range on Protein: 556-601
Range on HMM: 88-137/270
Sequence Identity: 34% (17 aa)

YCPNGDLLDFVIK----RGALRESQARFFFKGVSKAVQYLQQRNICHRDL
|.|.|||||.  |    ...|  ..   .   ..|. .|| ..|. ||||
YMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 13750.AA Ciliate-E9 477-545 28 0.001262 7.02 In-house 1-68 (298) Show / Hide 
Range on Protein: 477-545
Range on HMM: 1-68/298
Sequence Identity: 28% (21 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNNLIAIKKFKKRKEHH------FESEHKILSLINGQHPNIIKIQSI
| . |.|. |    | ||  |.      .   .||| .|...         |  | .||. . . |..||. | |
YRVHRNIAQGTQGQVKLAIDMQ------TRKKYAIKIMKHQQMNDEMFFKYFQREMNILNQVQP-HRYIIQLQDI
Kinase 13750.AA Pkinase_Tyr 477-541 25 0.518457 4.05 Pfam 1-68 (270) Show / Hide 
Range on Protein: 477-541
Range on HMM: 1-68/270
Sequence Identity: 25% (18 aa)

YKIERKIGDGCSSVVYLAKEMDELNNILSNNLIAIKKFKKRKEHH------FESEHKILSLINGQHPNIIK
 .. .|.| |.  .||...  .       .   |.|. |    |.      | .| ||.. . |.||||..
ITFGKKLGEGAFGEVYKGTWKG--DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL-GHHPNIVR