Gene 16913 (Tetrahymena)

16913

Species: Tetrahymena
Alias: PreTt16913, 112.m00157, TTHERM_00713620, 1057, 16913
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A2

Sequence

Name Sequence Type Origin Length Description Download
16913.AA Protein None 804 None Fasta, JSON
16913.kin_dom Protein Kinase Domain None 268 None Fasta, JSON
16913.NA RNA None 2415 None Fasta, JSON

Protein domain

Protein domains of 16913.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 16913.AA Ciliate-A2 64-321 54 4.5e-154 518.15 In-house 2-272 (272) Show / Hide 
Range on Protein: 64-321
Range on HMM: 2-272/272
Sequence Identity: 54% (147 aa)

KGSFDKIIIAENL--ISKSQQAIKIISIFDGIDQ-VSQKKLQDAKKEALFLKNTNHQNIVKYCDEFQIGFNYFIVMEKC-EKNLQQFIEDFKSQETEIPK
.|.| ..|..|    . ... ||||.||.||||| .||.|||..|.||.||||.||.|||||.|||||||.|||.|||| |..||..|..|..|...||.
QGCFGCVIFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIPD

HIIVNFACQILSVINYLRQQNLVLRDLSLRNILIDNHNQ-IKLYDVGLVKQVQEEFTFSLILTTFPKRSLFYYPPELFEQ-FEMSGEQNKKDQFKNLLDG
|..|.||||||. |.||...| |||||||||||||..|| |||.| ||.|..|.|.. ....|..||...||||||...| |||.||||||.|.|. ..|
HQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQCFEMNGEQNKKQQIKQTFMG

DIWAFGICLYALAGASQQEFSSLK---SKG---YQKLTSLDKSLNSILSQILSLDPNQRP-SILQLIDTFE
||||||||||.|.||.||....|.   .|.   ||....||...|.|..|||..||..|| ||.|......
DIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH
Kinase 16913.AA Ciliate-E6 108-263 35 1.6e-38 120.27 In-house 1-154 (154) Show / Hide 
Range on Protein: 108-263
Range on HMM: 1-154/154
Sequence Identity: 35% (55 aa)

ALFLKNTNHQNIVKYCDEFQIGFNYFIVMEKCEKNLQQFIEDFKSQETEIPKHIIVNFACQILSVINYLRQQNLVLRDLSLRNILIDNHNQIKLYDVGLV
. .||| ||.||.|| |.||| ..||||||.||.|||. |.  |     . . . ..|.||......|| ..|.||  ..|.|| .|.   ||. | |. 
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICDFGFQ

KQVQEEFTFSLILTTFPKRSLFYYPPELFEQFEMSGEQNKKDQFKNL-LDGDIWAFG
. .       ...  ..   ..| |||.|    .| .|  | .  |.   ||||  .
QCIIPNQQTKEFMAQKNQNKYHYCPPEQFD---YSKDQQSKHYKVNWTQEGDIWSVC
S_TKc 16913.AA S_TKc 55-329 21 1.1e-21 79.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 55-329
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

LRVIDLDGQKGSFDKIIIAENLISKSQQAIKIISIFDGIDQVSQKKLQDAKKEALFLKNTNHQNIVKYCDEFQIGFNYFIVMEKCEK---NLQQFIEDFK
 ..... | ||.| |   . .  .. . |||||.             .....|   ||. .| ||||. | ||   ....||| |.    .| ..|.. .
YEILRKIG-KGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

SQETE--IPKHIIVNFACQILSVINYLRQQNLVLRDLSLRNILIDNHNQIKLYDVGLVKQVQEEFTFSLILTTFPKRSLFYYPPELFEQFEMSGEQNKKD
.. .   .|   .  ...||.. ..|. ... . |||   |||.|.  .||. | || .|.           |    ...| .||..             
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-------------

QFKNLLDG---DIWAFGICLYALAGASQQEFSSLKSKGYQKLTSLDKSLNSILSQILSLDPNQRPSILQLIDTFEDMRKQIWT
      ..   |.|..|..|| ..   .  |.    . ..|.   .... ......|  ||..||.. ..    .| ..  | 
----GYGKCKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 16913.AA Ciliate-E2-Unclassified 64-269 21 2.7e-19 63.58 In-house 9-263 (352) Show / Hide 
Range on Protein: 64-269
Range on HMM: 9-263/352
Sequence Identity: 21% (59 aa)

KGSFDKIIIAENLISKSQQ-----AIKIISIFDGIDQVSQKKLQDAKKEALFLKNTNHQN-----------------IVKYCDEFQIGFNYFIVMEKCE-
.|.| |.  ...   | |.     ..||... . . . ..  .   .||   .|. .||.                 |||....||  .| .||||.|| 
QGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEG

KNLQQFIEDFKS------------QETE-IPKHIIV-----NFACQILSVINYLRQQN-LVLRDLSLRNILIDNHN---QIKLYDVGLVK----------
..|.|.|...|.            .... ..   ..     ... |||. ..|| ..|  . ||. . |||.|| .   .||. | |. |          
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDT

---------QVQEEFTFSLILTTFPKRSLFYYPPELFEQFEMSGEQNKKDQFKNLLDGDIWAFGICLYAL
         . |.  ||.  . . | .   | .||.... . ...             |||..|..||..
NQQQKMQIWKQQMMWTFCGTPNYMP-Q---YTAPEVLQGQNYDHSKA--------YKCDIWSLGVILYEM
Kinase 16913.AA Ciliate-E2 64-318 16 4.1e-16 51.81 In-house 9-361 (365) Show / Hide 
Range on Protein: 64-318
Range on HMM: 9-361/365
Sequence Identity: 16% (62 aa)

KGSFDKIIIAENLISKSQQAIK--------------IISIFDGIDQVSQKKLQDAKKEALFLK----------------NTNHQNIVKYCDEFQ--IGFN
.|.| ..  ...   . |.|||                . .  . ........  |.|   ..                . || ||.|. . ||     |
QGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNN

YFIVMEKCEK-NLQQFIEDFKS--------------QET-EIPKHIIV-------NFACQILSVINYLRQQN-LVLRDLSLRNILIDNHNQIKLYDVGLV
...||| |.  .|...|...|               .|  .| |.|.        .....|.. ..|| ..|  . ||. . |||.     ||. | || 
IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLS

KQVQE------------EFTFSLILTTFPKR----------------SLFYYPPELFE------QFEMSGEQNKKDQFKNLLDGDIWAFGICLYALAGAS
|....            ...|    |.   .                .. | .|| ..      |         ..|       |||..|..|| .    
KKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---------QKQKGYDYKCDIWSLGVILYEML-FG

QQEFSSLKSKGYQKLTSLDKSLN--------------------------SILSQ----ILSLDPNQRPS-ILQLID
.  |       .|.    . ...                           ....    .|  ||..|.. . |...
KPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 16913.AA NEK6 57-206 29 9.8e-15 44.68 In-house 2-149 (252) Show / Hide 
Range on Protein: 57-206
Range on HMM: 2-149/252
Sequence Identity: 29% (45 aa)

VIDLDGQKGSFDKIIIAENLISKSQQAIKIISIFDGIDQVSQKKLQDAKKEALFLKNTNHQNIVKYCDEFQIGFNYFIVMEKCEK-NLQQFIEDFKSQET
 |.    || |  .  |. |. . . |.| . ||. .|   .|  ||  ||   ||. ||.|..|| . |    .  ||.|  .   . . |  || |. 
QIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMD---AKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKHFKKQKR

EIPKHIIVNFACQILSVINYLRQQNLVLRDLSLRNILIDNHNQIKLYDVGL
 || . |  .  |. | .. . .. .. ||.   |. |  .  .|| |.||
LIPERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGL
Kinase 16913.AA CAMK 64-212 17 1.5e-13 39.31 In-house 4-248 (425) Show / Hide 
Range on Protein: 64-212
Range on HMM: 4-248/425
Sequence Identity: 17% (42 aa)

KGSFDKIIIAENLISKSQQ------------AIKIISIFDGIDQV----------------------SQKKLQDAKKEALFLKN-------TNHQNIVKY
.||| |   ...  .. ..            |||||.     |..                      ..|...  ..|   .|.        .| ||.| 
RGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKL

CDEFQ---------IGF-----------NYFIVM---EKCEKN-----LQQFIEDFKSQETE-----------IPKHIIVNFACQILSVINYLRQQNLVL
 . ..         . .           ....||   | |.       | ..| . ..   |           .. .    .  ||.| ..|. ..| | 
YEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVH

RDLSLRNILIDNH-----------------NQIKLYDVGLVKQVQE
||| . |||.|..                 |.||. | |. .....
RDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDP
Kinase 16913.AA TKL 83-320 14 1e-12 42.14 In-house 30-364 (364) Show / Hide 
Range on Protein: 83-320
Range on HMM: 30-364/364
Sequence Identity: 14% (51 aa)

AIKIISIFDG---------------------IDQVSQKKLQDAKKEALFLKNTNHQNIVKYCD-EFQIGF------------NYFIVMEKCEK-N-LQQF
|.|.... .                      .|. ...  .  ..|.. .....|.|||..    .....            ...|||| |.. . | ..
AVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYL

IEDFKSQETEIPKHIIVNFACQILSVINYLRQQN--------LVLRDLSLRNILIDNHNQ--------------IKLYDVGLVKQVQEEFTFSLIL----
.            | ....| .| . .||| ..|        .. |||  .|||.|....              .|. | || . .....  . .     
H-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMM

----------TTFPKR-SLFYYPPELFEQFEMSGEQN--KKDQFKNLLDG---DIWAFGICLYALAG----ASQQEFS------------SLKS-KGYQK
          || ... .. . .||.... .   | .   . ..|..      |...|||.|. ..      ... ..            .. . ||.. 
ESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRP

LTS--------------LDKSLNSILSQILSLDPNQRPSILQLIDTF
.                 ..|. ... .  . ||..||| .......
PIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 16913.AA Abl 100-213 26 3.4e-12 36.49 In-house 38-150 (252) Show / Hide 
Range on Protein: 100-213
Range on HMM: 38-150/252
Sequence Identity: 26% (31 aa)

KLQDAKKEALFLKNTNHQNIVKYCDEFQIGFNYFIVME-KCEKNLQQFIEDFKSQETEIPKHIIVNFACQILSVINYLRQQNLVLRDLSLRNILIDNHNQ
....  |||  .|.  |.|.|.          ..|. |  |  || ... .  ....|.|  ...  | || | ..|| ... . |||  || |. .|. 
EVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRE--CDREELPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHI

IKLYDVGLVKQVQEE
.|. | || . ....
VKVADFGLARMMKDD
Kinase 16913.AA TBCK 134-206 29 5.7e-12 39.09 In-house 54-130 (346) Show / Hide 
Range on Protein: 134-206
Range on HMM: 54-130/346
Sequence Identity: 29% (23 aa)

IVMEKCEKNLQQFIEDFKSQETEIPKHIIVNFACQILSVINYLRQQNLVLRDLSLRNILIDNHN----QIKLYDVGL
.||| .. ||   ||      | ..   | ... |||. ..|.  ...| | |.. ||..|  .    ..||   ||
VVMEHYKMNLEDQIEIYAKRHTPKDCSQILCIYYQILCGLSYMHKHHIVHRFLHPHNIYLDDNGNQKLHVKLANYGL
Kinase 16913.AA Pkinase 99-270 25 5.3e-11 39.99 Pfam 40-206 (293) Show / Hide 
Range on Protein: 99-270
Range on HMM: 40-206/293
Sequence Identity: 25% (47 aa)

KKLQDAKK--EALFLKNTNHQNIVKYCDEFQIGFNYFIVMEKCEKNLQQFIEDF----KSQETEI--PKHIIVNFACQILSVINYLRQQNLVLRDLSLRN
.|.| . .  |.  .|. || |||.. | |. . .. .||| ||. |   .. |     .... .  . . . ... |||. ..|. ... . ||| . |
WKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPEN

ILIDNHNQI----KLYDVGLVKQVQEEFTFSLILTTFPKRSLFYYPPELFEQFEMSGEQNKKDQFKNLLDGDIWAFGICLYALA
|||||...|    |. | || ||..   . .   .| .  ...| .||.             .. .     |.|..|. || ..
ILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR-----------GGQYYGPKVDMWSCGCILYEML
Kinase 16913.AA TK 79-213 14 5.6e-11 32.26 In-house 52-312 (486) Show / Hide 
Range on Protein: 79-213
Range on HMM: 52-312/486
Sequence Identity: 14% (38 aa)

KSQQAIKIISIFDGIDQVSQKK--LQDAK-------KEALFLKNTN-----HQNIVKYC-----DEFQIGFN-------YFIVMEKCE-KN----LQQFI
| . |.|..   |. .|  ..   ..| .       .||. .|  .     |.|||.       .| ...|.       . |||| ..  .    |... 
KTPVAVKMLKEGDAMSQEEFFDEEMHD-RDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYL

EDFKSQETE------------------------------------------------------------------------IPKHIIVNFACQILSVINY
 . .  ...                                                                        .. |  . ...|| .   |
RKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEY

LRQQ------NLVLRDLSLRNILIDNHNQ-----------IKLYDVG--------LVKQVQEE
| ..      |.| |||  ||.|....|.           .|. | |        | . ....
LHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSD
Kinase 16913.AA TyrKc 58-320 18 3.9e-10 -58.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 58-320
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

IDLDGQ--KGSFDKIIIAENLISKSQQAIKIISIFDGIDQVSQKKLQDAKKEALFLKNT--NHQNIVKY----CDEFQIGF----NYFIVMEKCEK-NLQ
| |. .   | | ..  ..      | |.| .             ..|  .||  ...   .|.|||.      ...   |     ..|||| ... .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLK

QFIEDFKSQETEIPKHIIVNFACQILSVINYLRQQNLVLRDLSLRNILIDNHNQIKLYDVGLVKQVQEE----FTFSLILTTF---PK--RSLFYYPPEL
... . . .   ..    ..|. || .  .|| ..|.. |||  ||.|... ...|  | || . . ..       . . ..     |    .  ..|| 
DYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

FEQFEMSGEQNKKDQFKNLLDG------DIWAFGICLYAL--------AG-----ASQQEFSSLKSKGYQKLTSLD----------KSLNSILSQILSLD
.                   .|      |.|.||.|.. .         |      | ||   .  .||      .          . . .| .|    |
I------------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

PNQRPSILQLIDTF
|..||.  .... |
PEDRPTFSEIHECF
Kinase 16913.AA Pkinase 287-320 19 0.006774 11.32 Pfam 259-293 (293) Show / Hide 
Range on Protein: 287-320
Range on HMM: 259-293/293
Sequence Identity: 19% (7 aa)

KLTSLDKSLNSILSQILSLDPNQRPSILQLIDT--F
. . ..... .... .| .||..||.. |.     |
F-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 16913.AA TK 298-320 30 0.011667 3.88 In-house 464-486 (486) Show / Hide 
Range on Protein: 298-320
Range on HMM: 464-486/486
Sequence Identity: 30% (7 aa)

ILSQILSLDPNQRPSILQLIDTF
.. |  ..||..||.  || . .
LMQQCWHYDPEDRPTFSQLHEQL
Kinase 16913.AA TK 258-267 40 0.09978 0.7 In-house 376-385 (486) Show / Hide 
Range on Protein: 258-267
Range on HMM: 376-385/486
Sequence Identity: 40% (4 aa)

DIWAFGICLY
|.|.||....
DVWSFGVLMW
Kinase 16913.AA TBCK 288-322 22 0.119323 1.54 In-house 312-346 (346) Show / Hide 
Range on Protein: 288-322
Range on HMM: 312-346/346
Sequence Identity: 22% (8 aa)

LTSLDKSLNSILSQILSLDPNQRPSILQLIDTFED
.  ....| .|. . |.  |  |||. .| .  . 
YHQMCEWLIQIIRKCLQMCPMKRPSPTELMEHPMF
TPR_1 16913.AA TPR_1 435-468 50 5.3e-11 42.4 Pfam 1-34 (34) Show / Hide 
Range on Protein: 435-468
Range on HMM: 1-34/34
Sequence Identity: 50% (17 aa)

DSCYYNLGIAYKDKGMLDEAIKAYQKCLEINPKK
   .|||| .|  .| .||||..|||.||.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
Kinase 16913.AA TPR_1 741-774 47 6.8e-11 42.01 Pfam 1-34 (34) Show / Hide 
Range on Protein: 741-774
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

DSCYYNLGIAYKAKGMMDKAIQSYKKCLSLNPNH
   .|||| .| ..|  |.||. |.|.|.||||.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 16913.AA TPR_1 605-638 50 2.7e-10 39.94 Pfam 1-34 (34) Show / Hide 
Range on Protein: 605-638
Range on HMM: 1-34/34
Sequence Identity: 50% (17 aa)

DSCLYNLGIAYKAKGMLDEAIKSYQKCLEINPKK
   .|||| .| ..| .||||. |||.||.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 16913.AA TPR_1 673-706 44 5.3e-10 38.91 Pfam 1-34 (34) Show / Hide 
Range on Protein: 673-706
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

DNCHMNLGLTYYDKGMLDDAIKSYQKCLKINPKH
 . . |||..|| .| .|.||. |||.|..||..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
Kinase 16913.AA TPR 741-774 44 6.4e-10 40.21 SMART 1-34 (34) Show / Hide 
Range on Protein: 741-774
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

DSCYYNLGIAYKAKGMMDKAIQSYKKCLSLNPNH
  ..|||| .| ..|  |.||. |.|.|.|.||.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 16913.AA TPR 435-468 47 1.2e-09 39.31 SMART 1-34 (34) Show / Hide 
Range on Protein: 435-468
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

DSCYYNLGIAYKDKGMLDEAIKAYQKCLEINPKK
  ..|||| .|  .| .||||..|||.||..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 16913.AA TPR_1 707-740 44 1.9e-09 36.94 Pfam 1-34 (34) Show / Hide 
Range on Protein: 707-740
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

DICYMNLGIAYKGKGMLEEAIQFYQKCLEINPKK
   . ||| .|  .| ..|||..|||.||.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 16913.AA TPR_1 469-502 50 2.7e-09 36.44 Pfam 1-34 (34) Show / Hide 
Range on Protein: 469-502
Range on HMM: 1-34/34
Sequence Identity: 50% (17 aa)

EICFYNLGIAYKAKGLIDEAIQSYQKCLEINPEK
   .|||| .| ..|  ||||. |||.||.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 16913.AA TPR 605-638 47 3.5e-09 37.74 SMART 1-34 (34) Show / Hide 
Range on Protein: 605-638
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

DSCLYNLGIAYKAKGMLDEAIKSYQKCLEINPKK
  ..|||| .| ..| .||||. |||.||..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 16913.AA TPR_1 537-570 41 5.4e-09 35.37 Pfam 1-34 (34) Show / Hide 
Range on Protein: 537-570
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DIYYMNLGLAYMEKGMLNEAIKQYQKCIEINPKE
   . |||..|...| ..|||. |||..|.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 16913.AA TPR 469-502 47 6.9e-09 36.77 SMART 1-34 (34) Show / Hide 
Range on Protein: 469-502
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

EICFYNLGIAYKAKGLIDEAIQSYQKCLEINPEK
  ..|||| .| ..| .||||. |||.||..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 16913.AA TPR 673-706 41 7e-09 36.75 SMART 1-34 (34) Show / Hide 
Range on Protein: 673-706
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DNCHMNLGLTYYDKGMLDDAIKSYQKCLKINPKH
  .. |||. || .| .|.||. |||.|...|..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 16913.AA TPR_1 639-672 50 7.9e-09 34.81 Pfam 1-34 (34) Show / Hide 
Range on Protein: 639-672
Range on HMM: 1-34/34
Sequence Identity: 50% (17 aa)

DICLYNLGIAYKAKGVYDEAIKSYYKCLEINPKH
   .|||| .| ..| |||||. | |.||.||..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 16913.AA TPR 639-672 47 8.7e-09 36.43 SMART 1-34 (34) Show / Hide 
Range on Protein: 639-672
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

DICLYNLGIAYKAKGVYDEAIKSYYKCLEINPKH
  ..|||| .| ..| |||||. | |.||..|..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 16913.AA TPR_1 571-604 41 1.7e-08 33.61 Pfam 1-34 (34) Show / Hide 
Range on Protein: 571-604
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DSCYFNLGIAYENKGMSGEAIKSYQKCVEINPQH
   ..||| .|...|   |||. |||..|.||..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 16913.AA TPR_1 503-536 44 1.8e-08 33.55 Pfam 1-34 (34) Show / Hide 
Range on Protein: 503-536
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

DTCLHNLGIAYKAKGLLDEAIKSYQKCIEINPKK
   . ||| .| ..| .||||. |||..|.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 16913.AA TPR_2 435-468 41 2.1e-08 33.84 Pfam 1-34 (34) Show / Hide 
Range on Protein: 435-468
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DSCYYNLGIAYKDKGMLDEAIKAYQKCLEINPKK
  ..|||| .|  .| .||||..|.|.|...|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 16913.AA TPR_1 401-434 41 3e-08 32.76 Pfam 1-34 (34) Show / Hide 
Range on Protein: 401-434
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DICFMNLAIAYKEKGMIDEAIKSYKKCLEINPKE
   . ||. .| ..|  ||||. |.|.||.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 16913.AA TPR_2 673-706 41 3.4e-08 33.07 Pfam 1-34 (34) Show / Hide 
Range on Protein: 673-706
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DNCHMNLGLTYYDKGMLDDAIKSYQKCLKINPKH
  ...|||. || .| .|.||. |.|.||..|..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 16913.AA TPR 707-740 41 3.8e-08 34.31 SMART 1-34 (34) Show / Hide 
Range on Protein: 707-740
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DICYMNLGIAYKGKGMLEEAIQFYQKCLEINPKK
  .. ||| .|  .| ..|||..|||.||..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 16913.AA TPR_2 605-638 41 5.3e-08 32.39 Pfam 1-34 (34) Show / Hide 
Range on Protein: 605-638
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DSCLYNLGIAYKAKGMLDEAIKSYQKCLEINPKK
  ..|||| .| ..| .||||. |.|.|...|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 16913.AA TPR 571-604 38 5.9e-08 33.68 SMART 1-34 (34) Show / Hide 
Range on Protein: 571-604
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

DSCYFNLGIAYENKGMSGEAIKSYQKCVEINPQH
  ...||| .|...|   |||. |||..|..|..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 16913.AA TPR 537-570 38 8.9e-08 33.08 SMART 1-34 (34) Show / Hide 
Range on Protein: 537-570
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

DIYYMNLGLAYMEKGMLNEAIKQYQKCIEINPKE
  .. |||..|. .| ..|||. |||..|..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
Kinase 16913.AA TPR_2 741-774 44 8.9e-08 31.6 Pfam 1-34 (34) Show / Hide 
Range on Protein: 741-774
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

DSCYYNLGIAYKAKGMMDKAIQSYKKCLSLNPNH
  ..|||| .| ..|  |.||. |.|.|.|.||.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 16913.AA TPR_2 537-570 32 1.9e-07 30.44 Pfam 1-34 (34) Show / Hide 
Range on Protein: 537-570
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

DIYYMNLGLAYMEKGMLNEAIKQYQKCIEINPKE
  ...|||..|...| . |||. |.|.....|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 16913.AA TPR 401-434 38 2.6e-07 31.55 SMART 1-34 (34) Show / Hide 
Range on Protein: 401-434
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

DICFMNLAIAYKEKGMIDEAIKSYKKCLEINPKE
  .. ||. .|  .| .||||. |.|.||..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 16913.AA TPR 503-536 41 3.4e-07 31.14 SMART 1-34 (34) Show / Hide 
Range on Protein: 503-536
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DTCLHNLGIAYKAKGLLDEAIKSYQKCIEINPKK
  .. ||| .| ..| .||||. |||..|..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 16913.AA TPR_2 571-604 32 4.4e-07 29.16 Pfam 1-34 (34) Show / Hide 
Range on Protein: 571-604
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

DSCYFNLGIAYENKGMSGEAIKSYQKCVEINPQH
  ...||| .|...|   |||. |.|.....|..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 16913.AA TPR_2 707-740 35 8.9e-07 28.07 Pfam 1-34 (34) Show / Hide 
Range on Protein: 707-740
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

DICYMNLGIAYKGKGMLEEAIQFYQKCLEINPKK
  ...||| .|  .| ..|||..|.|.|...|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 16913.AA TPR_2 469-502 41 2e-06 26.72 Pfam 1-34 (34) Show / Hide 
Range on Protein: 469-502
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

EICFYNLGIAYKAKGLIDEAIQSYQKCLEINPEK
  . |||| .| ..|  ||||. |.|.|...|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 16913.AA TPR_2 503-536 35 2e-06 27.04 Pfam 1-34 (34) Show / Hide 
Range on Protein: 503-536
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

DTCLHNLGIAYKAKGLLDEAIKSYQKCIEINPKK
  ...||| .| ..| .||||. |.|.....|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 16913.AA TPR_2 401-434 35 5e-06 25.3 Pfam 1-34 (34) Show / Hide 
Range on Protein: 401-434
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

DICFMNLAIAYKEKGMIDEAIKSYKKCLEINPKE
  . .||. .| ..|  ||||. |.|.|...|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 16913.AA TPR_2 639-672 44 2.7e-05 22.8 Pfam 1-34 (34) Show / Hide 
Range on Protein: 639-672
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

DICLYNLGIAYKAKGVYDEAIKSYYKCLEINPKH
  ..|||| .| ..| |||||. | |.|...|..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_ASK_2 16913.AA TPR_ASK_2 418-434 47 0.000226 12.26 In-house 30-46 (46) Show / Hide 
Range on Protein: 418-434
Range on HMM: 30-46/46
Sequence Identity: 47% (8 aa)

DEAIKSYKKCLEINPKE
|.||..|.|  ||.| .
DQAIHWYRKGFEIQPNH
TPR_ASK_2 16913.AA TPR_ASK_2 682-706 35 0.000226 12.26 In-house 19-46 (46) Show / Hide 
Range on Protein: 682-706
Range on HMM: 19-46/46
Sequence Identity: 35% (10 aa)

TYYD---KGMLDDAIKSYQKCLKINPKH
.| |    . .| ||..| |  .|.| |
QYTDEAARESRDQAIHWYRKGFEIQPNH
TPR_ASK_2 16913.AA TPR_ASK_2 515-536 40 0.000229 12.24 In-house 25-46 (46) Show / Hide 
Range on Protein: 515-536
Range on HMM: 25-46/46
Sequence Identity: 40% (9 aa)

AKGLLDEAIKSYQKCIEINPKK
| ...|.||..| |  ||.|  
ARESRDQAIHWYRKGFEIQPNH
TPR_ASK_2 16913.AA TPR_ASK_2 617-638 40 0.000462 11.26 In-house 25-46 (46) Show / Hide 
Range on Protein: 617-638
Range on HMM: 25-46/46
Sequence Identity: 40% (9 aa)

AKGMLDEAIKSYQKCLEINPKK
| . .|.||..| |  ||.|  
ARESRDQAIHWYRKGFEIQPNH
TPR_ASK_2 16913.AA TPR_ASK_2 445-468 37 0.001065 10.09 In-house 20-46 (46) Show / Hide 
Range on Protein: 445-468
Range on HMM: 20-46/46
Sequence Identity: 37% (10 aa)

YKD---KGMLDEAIKAYQKCLEINPKK
| |    . .|.||. | |  ||.|  
YTDEAARESRDQAIHWYRKGFEIQPNH
TPR_1 16913.AA TPR_1 367-400 35 0.001207 16.71 Pfam 1-34 (34) Show / Hide 
Range on Protein: 367-400
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

ETYWHYLGYTQNELNFFSESIKSYQKCLEINPKK
   |  ||... ... . | |. |||.||.||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
Kinase 16913.AA TPR_ASK_2 758-774 47 0.002161 9.1 In-house 30-46 (46) Show / Hide 
Range on Protein: 758-774
Range on HMM: 30-46/46
Sequence Identity: 47% (8 aa)

DKAIQSYKKCLSLNPNH
|.|| .|.|   ..|||
DQAIHWYRKGFEIQPNH
TPR_ASK_2 16913.AA TPR_ASK_2 656-672 52 0.004708 8.01 In-house 30-46 (46) Show / Hide 
Range on Protein: 656-672
Range on HMM: 30-46/46
Sequence Identity: 52% (9 aa)

DEAIKSYYKCLEINPKH
|.||..| |  ||.| |
DQAIHWYRKGFEIQPNH
TPR_ASK_2 16913.AA TPR_ASK_2 589-604 50 0.011335 6.78 In-house 31-46 (46) Show / Hide 
Range on Protein: 589-604
Range on HMM: 31-46/46
Sequence Identity: 50% (8 aa)

EAIKSYQKCVEINPQH
.||..| |  ||.| |
QAIHWYRKGFEIQPNH
TPR 16913.AA TPR 367-400 32 0.017948 15.46 SMART 1-34 (34) Show / Hide 
Range on Protein: 367-400
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

ETYWHYLGYTQNELNFFSESIKSYQKCLEINPKK
  .|  ||     .. . | |. |||.||..|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 16913.AA TPR_2 367-400 26 0.018594 12.78 Pfam 1-34 (34) Show / Hide 
Range on Protein: 367-400
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

ETYWHYLGYTQNELNFFSESIKSYQKCLEINPKK
  .|..||    ... . | |. |.|.|...|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_ASK_2 16913.AA TPR_ASK_2 481-502 40 0.021255 5.9 In-house 25-46 (46) Show / Hide 
Range on Protein: 481-502
Range on HMM: 25-46/46
Sequence Identity: 40% (9 aa)

AKGLIDEAIQSYQKCLEINPEK
| .. |.|| .| |  ||.|  
ARESRDQAIHWYRKGFEIQPNH
TPR_ASK_2 16913.AA TPR_ASK_2 547-570 29 0.044047 4.88 In-house 20-46 (46) Show / Hide 
Range on Protein: 547-570
Range on HMM: 20-46/46
Sequence Identity: 29% (8 aa)

YME---KGMLNEAIKQYQKCIEINPKE
| .    . ...||. | |  ||.| .
YTDEAARESRDQAIHWYRKGFEIQPNH
Kinase 16913.AA TPR_ASK_2 717-740 29 0.060315 4.44 In-house 20-46 (46) Show / Hide 
Range on Protein: 717-740
Range on HMM: 20-46/46
Sequence Identity: 29% (8 aa)

YKG---KGMLEEAIQFYQKCLEINPKK
| .    . ...||  | |  ||.|  
YTDEAARESRDQAIHWYRKGFEIQPNH
Kinase 16913.AA TBCK 712-740 41 0.227576 0.52 In-house 307-333 (346) Show / Hide 
Range on Protein: 712-740
Range on HMM: 307-333/346
Sequence Identity: 41% (12 aa)

NLGIAYKGKGMLEEAIQFYQKCLEINPKK
|.|| |....  |. ||.  |||  .|.|
NIGIPYHQMC--EWLIQIIRKCLQMCPMK
TPR_ASK_2 16913.AA TPR_ASK_2 387-400 42 0.674244 1.06 In-house 33-46 (46) Show / Hide 
Range on Protein: 387-400
Range on HMM: 33-46/46
Sequence Identity: 42% (6 aa)

IKSYQKCLEINPKK
|..| |  ||.|  
IHWYRKGFEIQPNH