25405

Species: Tetrahymena
Alias: 22.m00350, 985, 25405, TTHERM_00257190, PreTt25405
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A2

Sequence

Name Sequence Type Origin Length Description Download
25405.NA RNA None 2319 None Fasta, JSON
25405.AA Protein None 772 None Fasta, JSON
25405.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 25405.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 25405.AA Ciliate-A2 31-288 47 3.5e-156 525.17 In-house 1-272 (272) Show / Hide
Range on Protein: 31-288
Range on HMM: 1-272/272
Sequence Identity: 47% (130 aa)

GSGAYGQVMTAKE---ENGEEVAIKIVSVFDEIDS-IDEQKLKEIKSEAQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKG-EMSLQEFVDKKLNQG--MS
|.|..|.|.....   .|.|..||||.|..|.||. |..|||.|.|.|||||..|.|||||.|..|||.|..|||.|||. |.|||...||. ||.  ..
GQGCFGCVIFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIP

EKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYN-IKLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVM-TNFNSEEKKSQKIYQNFD
...||..|.|.|.||.|||.|||||||.||.|.|.|.|.. ||||||||||...|....|.|..|..|||.||.|||.... ...|.|..|.|.|.|.|.
DHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQCFEMNGEQNKKQQIKQTFM

GDVWAFGVCMYLLGGASFLHVLQLT----QGKETFQLSKLVSIEINQILLNTLQLDPKLRP-SIDKIIQDFK
||.||||.|.|.||||.. |...||     .....| ........|||....|..|||.|| ||..|.....
GDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH

Kinase 25405.AA Ciliate-E6 75-228 38 2.4e-55 174.45 In-house 1-154 (154) Show / Hide
Range on Protein: 75-228
Range on HMM: 1-154/154
Sequence Identity: 38% (60 aa)

AQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKGEMSLQEFVD-KKLNQGMSEK-LFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLA
.|.|. | ||||. | ..||    ||| ||. ||.||  .  .|...    . .|.| ..|...|..|||||||||  |.|||  |||..|||.||||. 
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICDFGFQ

KEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVWAFG
..|.|  .|..|. ..    ..|.||| . . . ....| . |. .   || |  .
QCIIPNQQTKEFMAQKNQNKYHYCPPEQFDYSK-DQQSKHY-KVNWTQEGDIWSVC

S_TKc 25405.AA S_TKc 24-288 24 1.5e-39 138.67 SMART 1-231 (231) Show / Hide
Range on Protein: 24-288
Range on HMM: 1-231/231
Sequence Identity: 24% (70 aa)

TVVNPNAGSGAYGQVMTAKEEN-GEEVAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKGEM---SLQEFVDKKLN
  .    |.||.|.|. ... . |..|||||..             . |..| | |.. |||||| ... ||  ..... ||  .    .| .. .|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

QG----MSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQK
.|    ..|    ... |...|..|.||.. . ||.   |.|||.  .||.||||||...           . . | ..| .||||              
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL--------------

IYQNFDGDVWAFGVCMYLLGGASFLHVLQLTQGKETFQLSKLVSIEINQILLNTLQLDPKLRPSIDKIIQ--------DFK
 |  .  |.|..|...| .     .      | ...|.. .  | |  ... . || ||. ||.. .. |         . 
GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 25405.AA CAMK 31-177 17 8.8e-35 108.97 In-house 3-248 (425) Show / Hide
Range on Protein: 31-177
Range on HMM: 3-248/425
Sequence Identity: 17% (44 aa)

GSGAYGQVMTAKEE-NG------------EEVAIKIVSVFDEIDSI----------------------DEQKLKEIKSEAQFLQMCH-------HPNIVS
|.|..|.|  ...  ..            ..|||||..     |.                       .....|....| . .....       ||||..
GRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIK

YKGEFQ------------LGSC--------YFIKM------EKGEM--SLQEFVDKKLN-------------QGMSEKLFVKLALQMLSAIQYLHSKNYV
    ..              |.        ... |      . ||.   | ... .. .               ..|.   ..  |..||..|.||.| |
LYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIV

LRDISLKNVLLDKD-----------------YNIKLCDFGLAKEINP
 ||. . |.|||..                 .|||..|||.|....|
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDP

Kinase 25405.AA STE 31-290 18 3.3e-32 111.06 In-house 8-359 (359) Show / Hide
Range on Protein: 31-290
Range on HMM: 8-359/359
Sequence Identity: 18% (66 aa)

GSGAYGQVMTAKEEN----------------GEEVAIKIVSVFDE-----------IDSIDEQKLKEIKSEAQFLQMCH--HPNIVSYKGEFQLG-----
|.||.|.| .|.  .                || .|||.... ..            ..........|. | .... |.  ||||| | | .  .     
GKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHK

--SCYFIKMEKGE-MSLQEFVD------KKLN------QGMSEKLFVKLALQMLSA-IQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQLA
  .  .| ||  .  || ....      | ||      . ..|..  . . | | .  .||||.... |||   |.||     .||||||... ... .|
NDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMA

------------TQA-FLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVWAFGVCM-------YLLGGASFLHVLQLTQ-------------
            |..   .. |     .  |||.   . .       .   ..  |.| .| ..       . .   . . .. ...             
NIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQG-R-----DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GKETFQL-----------------SKLVSIEINQILLNTLQLDPKLRPSIDKIIQD-FKNI
    .  ...                  .. .| | .. . . || ||. ||. .. ...  . |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 25405.AA TKL 30-232 17 1.2e-30 107.58 In-house 1-280 (364) Show / Hide
Range on Protein: 30-232
Range on HMM: 1-280/364
Sequence Identity: 17% (52 aa)

AGSGAYGQVMTAKEEN---------GEEVAIKIVSV--FDEIDS-----------------IDEQKLKEIKSEAQFLQMCH--HPNIVSYKG--------
 |||..|.|  .|  .         |..||.|. ..   || ..                  .|..  . . | . ..|    |||||...|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------------EFQ-LGS-CYFIKMEKGEMSLQEFVDKKLNQGMSEKLFVKLALQMLSAIQYLHS--------KNYVLRDISLKNVLLDKDYN-
                 |.   || ....                        .....||.. ....||||        .. . ||.  ||.|.|.... 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTN

-------------IKLCDFGLAKEINPQLA---------------TQAFLQSQVKGVLFYFPPEVLVMTNFNS-----EEKKSQKIYQNFDGDVWAFGVC
             .|.|||||......                  ...   . . | . . .|||| ......     .| . ..   .   ||..||..
VSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIV

MY
..
LW

Kinase 25405.AA Pkinase 31-229 25 1.6e-30 109.03 Pfam 8-200 (293) Show / Hide
Range on Protein: 31-229
Range on HMM: 8-200/293
Sequence Identity: 25% (54 aa)

GSGAYGQVMTAKEENGEE-VAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKGEM-----SLQEFVD---KKLNQG
|||..|.|  ... . .. ||.||... .| .. |.....   ||.| .....||||| ... |. .. . . ||  |.     .| ...    ..    
GSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-

MSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNI----KLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIY
.||.   . ..|.|....|.||.. . ||. . |.|.|....|    |.||||||| ..  .  .  ... . | ..| .|||.               |
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFC-GTPWYMAPEVIR-----------GGQY

QNFDGDVWAFGV
     |.|..|.
YGPKVDMWSCGC

Kinase 25405.AA AGC 31-232 18 2.6e-30 74.24 In-house 8-296 (395) Show / Hide
Range on Protein: 31-232
Range on HMM: 8-296/395
Sequence Identity: 18% (56 aa)

GSGAYGQVMTAKE-------ENGEEVAIKIVSVFDE-IDSIDEQKLKEIKSE------------AQFLQMCH----------HPNIVS-YKGEFQLGSC-
| |..|.|. ...        .|.  |.|...  .. |  ....... ...|             . |..|.          ||.||.  .  ||  .  
GKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLK-KKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHT

-YFIKME------------KG-EMSLQEFVDKKLNQG-MSEKLFVKLALQ-------MLSAIQYLHS-KNYVLRD-ISLKNVLLDKDYNIKLCDFGLAKE
  .. ||             | |. |. . .  ...| ..|.     | .       ...|..|||| .... || . . |.|||.| .|||.||||.||
YLYFVMEYMPRYVNDLYCGGGCELFLHLQGR--RKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKE

INPQ-----------------------------------------------LATQAFLQSQVKG--VLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVW
..                                                    . .. .   |     | .||.|                 ..  | |
GMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL----------------YGKACDWW

A--FGVCMY
.  .|..||
SFGLGCLMY

Kinase 25405.AA CAMKL 31-177 28 4.8e-30 92.95 In-house 8-181 (297) Show / Hide
Range on Protein: 31-177
Range on HMM: 8-181/297
Sequence Identity: 28% (49 aa)

GSGAYGQVMTAKE-EN-GEEVAIKIVSVF----DEIDSID------EQKLKEIKSEAQFLQMCH---HPNIVSYKGEFQLGSC------YFIKMEKGEMS
| |..|.|  |.   . ||.|||||.  .    |.. .        |...  |. |.| ..| .   ||||..    ..  ..      ... ||  .  
GKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG

---LQEFVDKKLNQG--MSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDY--NIKLCDFGLAKEINP
   |.....|. . .  |.|.   ..  |..||..|.||.. | ||| . |.|||..   |||..|||.. .. |
EMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRP

Kinase 25405.AA Ciliate-E2 24-285 16 2.5e-25 83.9 In-house 1-361 (365) Show / Hide
Range on Protein: 24-285
Range on HMM: 1-361/365
Sequence Identity: 16% (64 aa)

TVVNPNAGSGAYGQVMTAKE-ENGEEVAIK--------------IVSVFDEIDSIDEQKLKEIKSEAQFLQ----------------MCHHPNIVSYKGE
  ..   |.|..|.|  .|  ......|||                . . .. .. ......||.| . ..                   ||||. ..  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ---LGSCYFIKMEKGEMSLQEFV---DKKLNQG------MSEKLFVKLALQMLS---------------AIQYLHSKN-YVLRDISLKNVLLDKDYNI
||     ..|..      ..|...    .|| |.       ..||   ..  | |.               |..||||||  . ||| . |.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGLAKEINPQ-----------LATQAF-----------------LQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVWAFGVCMYLLGG
|..||||.|.....           . .. .                 .. .. | . | .||.| . . . .   ... . ..  |.|..||..| .  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---QKQKGYDYKCDIWSLGVILYEMLF

ASFLHVLQLTQGKETFQLSKLVSIEIN--------------------------QILLN----TLQLDPKLRPS-IDKIIQ
  .            .|  |   |...                          ... .     || ||. |.. ...|..
GKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

Kinase 25405.AA ULK 123-232 24 4.9e-16 53.43 In-house 124-243 (324) Show / Hide
Range on Protein: 123-232
Range on HMM: 124-243/324
Sequence Identity: 24% (32 aa)

SEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYN------------IKLCDFGLAKEINPQLATQAFLQSQV-----KGVLFYFPPEVLVMTN
||.  ..   | ... ..||..|.. ||| . | |. ..              .|..|||.|| ..     |  .|..|     ||   |  |..|    
SEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQIL----

FNSEEKKS--QKIYQNFDGDVWAFGVCMY
     ..   || | ..  |.| .|. .|
-----QGQGEQKPYYDYKCDIWSLGCIFY

Kinase 25405.AA TK-Unique 123-232 31 1.6e-15 50.08 In-house 129-230 (294) Show / Hide
Range on Protein: 123-232
Range on HMM: 129-230/294
Sequence Identity: 31% (35 aa)

SEKLFVKLALQMLSAIQYLHS--KNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNF
|.|...  | |  .. .||.|  |. | ||.. .||||  |...|.||||.|....     ..  .|| .  . . .||.|  .         ...| . 
SPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPIRWMAPESLKCY---------HGMYHTT

DGDVWAFGVCMY
 .|||.||| |.
KSDVWSFGVLMW

Kinase 25405.AA TyrKc 24-287 20 4.5e-15 20.98 SMART 1-280 (280) Show / Hide
Range on Protein: 24-287
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

TVVNPNAGSGAYGQVMTAKEENGEEVAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMC--HHPNIVSYKGEFQLG-------SCYFIKMEKGEM-SLQEF
 . .   |.||.|.|. ..    ..||.| .             .... .||. . .   ||||||   |    .         ..| ||  .  .|...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

VDKKLNQGMSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQ----LATQAFLQS---QVK--GVLFYFPPEVLVMT
  |. ..  . | ... ..|  .  .||||||.. ||.   |.|..... .| .||||...|        ...   ..   . |    .   .||..   
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---

NFNSEEKKSQKIYQNFDGDVWAFGVCMY--------LLGG-----ASFLHVLQLTQGKETFQLSKL--------VSIEINQILLNTLQLDPKLRPSIDKI
          ... ..  |||.|||||.           |      |  .|... .  .     .          . |. || .   . ||. ||.   |
--------NYGKF-TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

IQDF
...|
HECF

Kinase 25405.AA Pkinase_Tyr 103-175 32 4.2e-11 38.23 Pfam 89-161 (270) Show / Hide
Range on Protein: 103-175
Range on HMM: 89-161/270
Sequence Identity: 32% (24 aa)

MEKGEMSLQEFVDKK--LNQGMSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEI
|..|  .| ..  |.   .|  . |  .. ..|  .. .||.|||.. ||.  .|.|....  .| ||||||. |
MPHG--DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI

Kinase 25405.AA ULK 31-90 22 8.4e-08 23.82 In-house 8-81 (324) Show / Hide
Range on Protein: 31-90
Range on HMM: 8-81/324
Sequence Identity: 22% (17 aa)

GSGAYG-QVMTAK-EEN---GEEVAIKIVSVFDEIDSIDEQK----LKEIKSEAQFLQMCH---HPN--IVSYK
|.|..| .|  .. ...   .. ||.|... .  ...  ||     .. .|.| | ... .   |||  || ..
GKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLY

Kinase 25405.AA Pkinase_Tyr 31-91 24 3e-06 21.97 Pfam 8-71 (270) Show / Hide
Range on Protein: 31-91
Range on HMM: 8-71/270
Sequence Identity: 24% (17 aa)

GSGAYGQVMTAKEE-----NGEEVAIKIVSVFDEIDSIDEQK--LKEIKSEAQFLQMC-HHPNIVSYKG
|.||.|.|. ..       .. .||.|..      .. ...   ...  .||. .    ||||||.. |
GEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYG

Kinase 25405.AA TK-Unique 253-287 22 3e-06 17.54 In-house 259-294 (294) Show / Hide
Range on Protein: 253-287
Range on HMM: 259-294/294
Sequence Identity: 22% (8 aa)

QLSKLV-SIEINQILLNTLQLDPKLRPSIDKIIQDF
.. . . | |. ... ...|..|. |||...|.. .
PQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase 25405.AA TK-Unique 24-88 26 0.00025 10.97 In-house 1-68 (294) Show / Hide
Range on Protein: 24-88
Range on HMM: 1-68/294
Sequence Identity: 26% (18 aa)

TVVNPNAGSGAYGQVMTAKEEN--GEEVAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMCH-HPNIVS
 .|. . |.||.||| ... ..  ... . |.| |    |. .... .. ..|.|...    |||||.
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQ

Kinase 25405.AA Pkinase 254-287 30 0.007972 11.07 Pfam 259-293 (293) Show / Hide
Range on Protein: 254-287
Range on HMM: 259-293/293
Sequence Identity: 30% (11 aa)

LSKLVSIEINQILLNTLQLDPKLRPSIDKIIQD--F
. ...| |  ... . |..||| ||... | |.  |
F-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 25405.AA CAMKL 258-286 31 0.066506 1.69 In-house 267-294 (297) Show / Hide
Range on Protein: 258-286
Range on HMM: 267-294/297
Sequence Identity: 31% (9 aa)

VSIEINQILLNTLQLDPKLRPSIDKIIQD
|| .  ...   || .|. ||.|. | ..
VS-DCRDLIRKMLQVNPEKRPTIHQIMNH

Kinase 25405.AA TKL 273-287 40 0.192447 0.97 In-house 350-364 (364) Show / Hide
Range on Protein: 273-287
Range on HMM: 350-364/364
Sequence Identity: 40% (6 aa)

DPKLRPSIDKIIQDF
||. ||| ..|.. .
DPEKRPSFQEILKRL

Kinase 25405.AA Pkinase_Tyr 223-232 70 0.208478 5.39 Pfam 196-205 (270) Show / Hide
Range on Protein: 223-232
Range on HMM: 196-205/270
Sequence Identity: 70% (7 aa)

DVWAFGVCMY
|||.|||.|.
DVWSFGVLMW

Kinase 25405.AA Pkinase_Tyr 261-287 25 0.50799 4.08 Pfam 244-270 (270) Show / Hide
Range on Protein: 261-287
Range on HMM: 244-270/270
Sequence Identity: 25% (7 aa)

EINQILLNTLQLDPKLRPSIDKIIQDF
|| ....   . ||. ||.   |....
EIYDLMKQCWHYDPEDRPTFSEIHEQL

TPR 25405.AA TPR 478-511 38 2e-08 35.27 SMART 1-34 (34) Show / Hide
Range on Protein: 478-511
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

FSPYYCLGIIYYERSEFDQSISYFNKALELNSSN
   .|.|| .|| . ..|. | ...|||||. .|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 25405.AA TPR_1 478-511 41 6.1e-08 31.7 Pfam 1-34 (34) Show / Hide
Range on Protein: 478-511
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

FSPYYCLGIIYYERSEFDQSISYFNKALELNSSN
   .| || .||.. ..|. | ...|||||| .|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_1 25405.AA TPR_1 648-681 26 4.1e-07 28.82 Pfam 1-34 (34) Show / Hide
Range on Protein: 648-681
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PNAQFLLGQVFEQIGKMDKAIKYFQEAIMIQAKY
..| . ||..... |. |.||...|.|. .. ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR 25405.AA TPR 444-477 26 2e-06 28.77 SMART 1-34 (34) Show / Hide
Range on Protein: 444-477
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PYSILQIGKCYFKKKMYEDAITSFKQVIKLLPTI
.   ...| ||.|.. |..||  ......| |. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 25405.AA TPR_1 444-477 26 2e-06 26.51 Pfam 1-34 (34) Show / Hide
Range on Protein: 444-477
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PYSILQIGKCYFKKKMYEDAITSFKQVIKLLPTI
.    ..| ||.|.. |..||  ......| |. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_2 25405.AA TPR_2 478-511 38 2e-06 26.6 Pfam 1-34 (34) Show / Hide
Range on Protein: 478-511
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

FSPYYCLGIIYYERSEFDQSISYFNKALELNSSN
.  .|.|| .||.. ..|. | |..|||.|.  |
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 25405.AA TPR 648-681 26 2e-06 28.94 SMART 1-34 (34) Show / Hide
Range on Protein: 648-681
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PNAQFLLGQVFEQIGKMDKAIKYFQEAIMIQAKY
. | . ||..... |. |.||...|.|. .. ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 25405.AA TPR_2 648-681 29 1e-05 24.42 Pfam 1-34 (34) Show / Hide
Range on Protein: 648-681
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

PNAQFLLGQVFEQIGKMDKAIKYFQEAIMIQAKY
. | ..|||. .. |. |.||.|...|. .  ..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_1 25405.AA TPR_1 716-749 26 1.4e-05 23.51 Pfam 1-34 (34) Show / Hide
Range on Protein: 716-749
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AKIYNELGKIYEKKQYLSQAINYFSECISLKPSE
|.... || .|.|.. . .|| .. ....| |. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_2 25405.AA TPR_2 716-749 29 1.6e-05 23.65 Pfam 1-34 (34) Show / Hide
Range on Protein: 716-749
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

AKIYNELGKIYEKKQYLSQAINYFSECISLKPSE
|.... ||..|.|.. . .||.|. ....| |  
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_2 25405.AA TPR_2 444-477 29 2.1e-05 23.22 Pfam 1-34 (34) Show / Hide
Range on Protein: 444-477
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

PYSILQIGKCYFKKKMYEDAITSFKQVIKLLPTI
..   ..|.||.|.. |..||  .....|| |. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 25405.AA TPR 716-749 26 2.5e-05 24.94 SMART 1-34 (34) Show / Hide
Range on Protein: 716-749
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AKIYNELGKIYEKKQYLSQAINYFSECISLKPSE
|.... || .|.|.  . .||........| |. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 25405.AA TPR_2 376-409 35 0.000269 19.29 Pfam 1-34 (34) Show / Hide
Range on Protein: 376-409
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

EIALSCMGYYYYEKNDLKQAMCYLQKCLNLNPKN
  |. ..|  ||...|...|  |..|.| |.|.|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 25405.AA TPR 376-409 35 0.000434 20.83 SMART 1-34 (34) Show / Hide
Range on Protein: 376-409
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

EIALSCMGYYYYEKNDLKQAMCYLQKCLNLNPKN
  |....|  || ..|...|. ..||.| |.|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 25405.AA TPR_1 376-409 35 0.000624 17.71 Pfam 1-34 (34) Show / Hide
Range on Protein: 376-409
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

EIALSCMGYYYYEKNDLKQAMCYLQKCLNLNPKN
  |.. .|. ||.......|  ..||.| |||.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_2 25405.AA TPR_2 512-545 29 0.001201 16.99 Pfam 1-34 (34) Show / Hide
Range on Protein: 512-545
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

QNCLYSLAKVYLETFNYSNAIEILNTLVRLFPSN
  ..| |...|..  .|  ||| .. ...|.| |
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_1 25405.AA TPR_1 580-613 29 0.002526 15.59 Pfam 1-34 (34) Show / Hide
Range on Protein: 580-613
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

ILALNCLAYYYFLKQQNQLAIQCLQSSIKVNPCN
  |.. |.. |. ... . ||.|.|  ...|| |
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR 25405.AA TPR 580-613 26 0.007139 16.79 SMART 1-34 (34) Show / Hide
Range on Protein: 580-613
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

ILALNCLAYYYFLKQQNQLAIQCLQSSIKVNPCN
. |...|.  |... . . ||.|.| .....| |
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 25405.AA TPR_2 682-715 29 0.024123 12.38 Pfam 1-34 (34) Show / Hide
Range on Protein: 682-715
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

ELPYIDLSQIYRKKGQYDDALFICKLALQNNIKS
   .  | |.|.|.|.||.|.  .. ||. . . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_2 25405.AA TPR_2 580-613 23 0.026596 12.23 Pfam 1-34 (34) Show / Hide
Range on Protein: 580-613
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ILALNCLAYYYFLKQQNQLAIQCLQSSIKVNPCN
  |...|.  |. ... . ||.... ..| .| |
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 25405.AA TPR 614-647 11 0.037471 13.12 SMART 1-34 (34) Show / Hide
Range on Protein: 614-647
Range on HMM: 1-34/34
Sequence Identity: 11% (4 aa)

FRAYFYQAQILLSEGKHEDAILSAKYSMQQNSKF
 .|.. ....... |....||   . ... . ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 25405.AA TPR_2 614-647 14 0.0393 11.63 Pfam 1-34 (34) Show / Hide
Range on Protein: 614-647
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

FRAYFYQAQILLSEGKHEDAILSAKYSMQQNSKF
..|.....|...  |....||   . . . . ..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 25405.AA TPR 512-545 29 0.064119 11.07 SMART 1-34 (34) Show / Hide
Range on Protein: 512-545
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

QNCLYSLAKVYLETFNYSNAIEILNTLVRLFPSN
  ..| |. .|.   .|  ||| ..  ..| |.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR 25405.AA TPR 410-443 14 0.069181 10.78 SMART 1-34 (34) Show / Hide
Range on Protein: 410-443
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

YRALTYKAFVLSNQQKLDEELLTLKEAISYNQNY
..|.  .. .. .. ..|| .  ...|.. . |.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR 25405.AA TPR 682-715 26 0.076625 10.39 SMART 1-34 (34) Show / Hide
Range on Protein: 682-715
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

ELPYIDLSQIYRKKGQYDDALFICKLALQNNIKS
   .  | ..|.|.|.||.|.  .. ||. . . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 25405.AA TPR_1 614-647 14 0.165505 9.25 Pfam 1-34 (34) Show / Hide
Range on Protein: 614-647
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

FRAYFYQAQILLSEGKHEDAILSAKYSMQQNSKF
 .|..  ...... |....||   .   . | ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR 25405.AA TPR 546-579 26 0.206313 6.61 SMART 1-34 (34) Show / Hide
Range on Protein: 546-579
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

DLYLATLALAYSEIKDEQKVMEFSQKSLQINPQN
  ..  |...|   .| .. .|. ||.|...|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 25405.AA TPR_1 546-579 26 0.212655 8.87 Pfam 1-34 (34) Show / Hide
Range on Protein: 546-579
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

DLYLATLALAYSEIKDEQKVMEFSQKSLQINPQN
   .  |...| . .. ..  |. || |..||.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR 25405.AA TPR 342-375 23 0.259813 5.73 SMART 1-34 (34) Show / Hide
Range on Protein: 342-375
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

DQYLALLGLTHLEQYQCEESRSISQKCLSINPKN
 ...  ||. .. . . .|     ||.|...|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 25405.AA TPR_1 515-545 35 0.521554 7.51 Pfam 4-34 (34) Show / Hide
Range on Protein: 515-545
Range on HMM: 4-34/34
Sequence Identity: 35% (11 aa)

LYSLAKVYLETFNYSNAIEILNTLVRLFPSN
.| |. .|..  ||  ||| ..  ..| |.|
WYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_2 25405.AA TPR_2 308-341 20 0.632621 7.36 Pfam 1-34 (34) Show / Hide
Range on Protein: 308-341
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

QTELFQQAQKEIDNHKYQEAQVTLERLVKINTHN
   .....|  . . .|.||   .|...|..  |
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_1 25405.AA TPR_1 690-715 34 0.795517 6.87 Pfam 9-34 (34) Show / Hide
Range on Protein: 690-715
Range on HMM: 9-34/34
Sequence Identity: 34% (9 aa)

QIYRKKGQYDDALFICKLALQNNIKS
..|.|.|.||.|.  .. ||. | . 
NCYYKMGNYDEAIECYQKALELNPNN

TPR_2 25405.AA TPR_2 546-579 23 0.916703 6.79 Pfam 1-34 (34) Show / Hide
Range on Protein: 546-579
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

DLYLATLALAYSEIKDEQKVMEFSQKSLQINPQN
  ..  |...| . .| ..  |. .|.|...|.|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_1 25405.AA TPR_1 410-443 17 2.607966 5.07 Pfam 1-34 (34) Show / Hide
Range on Protein: 410-443
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

YRALTYKAFVLSNQQKLDEELLTLKEAISYNQNY
..|.. .. .. .....|| .  ...|.. | |.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_1 25405.AA TPR_1 366-375 60 8.380836 3.3 Pfam 25-34 (34) Show / Hide
Range on Protein: 366-375
Range on HMM: 25-34/34
Sequence Identity: 60% (6 aa)

QKCLSINPKN
||.|..||.|
QKALELNPNN

TPR_2 25405.AA TPR_2 342-375 23 12.213169 2.81 Pfam 1-34 (34) Show / Hide
Range on Protein: 342-375
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

DQYLALLGLTHLEQYQCEESRSISQKCLSINPKN
  .. .||. ...| . .| .   .|.|...|.|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR_2 25405.AA TPR_2 410-443 17 21.226883 1.96 Pfam 1-34 (34) Show / Hide
Range on Protein: 410-443
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

YRALTYKAFVLSNQQKLDEELLTLKEAISYNQNY
 .|. . . .. .|...|| .  ...|.... |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN