5933

Species: Tetrahymena
Alias: TTHERM_01084140, 3801.m00213, PreTt05933, 5933, 1003, 225.m00036
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E4

Sequence

Name Sequence Type Origin Length Description Download
5933.AA Protein None 1073 None Fasta, JSON
5933.kin_dom Protein Kinase Domain None 93 None Fasta, JSON
5933.NA RNA None 3222 None Fasta, JSON

Protein domain

Protein domains of 5933.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5933.AA Ciliate-E4 21-39 47 0.007847 5.92 In-house 1-19 (150) Show / Hide
Range on Protein: 21-39
Range on HMM: 1-19/150
Sequence Identity: 47% (9 aa)

YSFIEDKQDLHYGQIKVFE
|  ||  .|.||| | . |
YRKIESVKDIHYGDIQIME

Kinase 5933.AA Ciliate-E4 110-204 50 2.1e-60 199.07 In-house 56-150 (150) Show / Hide
Range on Protein: 110-204
Range on HMM: 56-150/150
Sequence Identity: 50% (48 aa)

KNLIDVYEYFIQTEEKFCSSVQRIQLVIEYLQRDIQIEVKTKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIKLLH
.|.|.|||||...|..||||..|.....||||.|.|...|..|.|.|.|...||..|||.|||..|.||.||..|||||.|||....||..|.. 
ENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQGQHFDESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD

Kinase 5933.AA Ciliate-A5 110-330 25 3.8e-26 87.65 In-house 46-275 (275) Show / Hide
Range on Protein: 110-330
Range on HMM: 46-275/275
Sequence Identity: 25% (60 aa)

KNLIDVYEYFIQTEEKFCSSVQRIQLVIEYLQRDIQIEVKTKKLQN--QRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIKLLHPLV
.|.. .. .  . .| |||.  .. .. ||   . . |.   | .    ... ||...|... |. .. ||  |. |||.. .||....  ..||    .
PNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMD--M

NKIVPSFA--TMISQLSYGEHFDTQG-IYLSPLLTKAVSQKN----YQPQHNPFKSDVFTLGIILIECCNLGTV-DNLYNYEAGDFNEN-QLKIHMNIIK
|    .|      |   | .| .|.   ||||.. ..   .      .| || .|||||.|| |. |.| .  .  . | ||     .|  .|.  .  .
NESKDFFYQINWSSYKQYQHHMSTENKQYLSPMQWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKE

NQYGVDVHDLIARMVKVQEQDRPDFIELATQL
  |.    ..|..|    | .||||.... .|
KKYSEQFINFIKQMLQFEENKRPDFHQIYQYL

Kinase 5933.AA Ciliate-B2 135-197 25 6.4e-09 17.0 In-house 78-140 (197) Show / Hide
Range on Protein: 135-197
Range on HMM: 78-140/197
Sequence Identity: 25% (16 aa)

LVIEYLQRDIQIEVKTKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEY
|..|  . . . |..  ..| . |. | .. . |  |. |  . . |  | |.| .|||....
LIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQN

S_TKc 5933.AA S_TKc 80-333 15 8.3e-08 -62.44 SMART 1-231 (231) Show / Hide
Range on Protein: 80-333
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)

YQDLDTI---------------DKDLVNMKQLIHITEENHKEKRTKNLIDVYEYFIQTEEKFCSSVQRIQLVIEYLQR---DIQIEVKTKKLQNQR--FT
|. |..|               .. .| .|..    |   .| .        .. ..  . | .  ... .| ||.     |     | .. .  |  |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

PQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIKL--------LHPLVNKIVPSFATMISQLSYGEHFDTQGIYLSP-LLTKAVSQKNYQPQ
. ..  ..   .. |  .   .  | ||| .|||..|  .||.        |                      .|     |..| .|           .
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------TTFCGTPWYMAPEVL-----------G

HNPFKSDVFTLGIILIECCNLGTV--DNLYNYEAGDFNENQLKIHMNIIKNQYGVDVHDLIARMVKVQEQDRPDFIELAT------QLNII
....|.|.  .|.||.|..  |    .            .. ..  .|       .. |.| .. ..  ..||   |. .      .   .
YGKCKCDWWSCGCILYEMLC-GYPPFP------------QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 5933.AA Ciliate-E1 97-259 17 4e-06 16.52 In-house 36-202 (202) Show / Hide
Range on Protein: 97-259
Range on HMM: 36-202/202
Sequence Identity: 17% (30 aa)

IHITEENHKEKRTKNLIDVYEYFIQTEEKFC-SSVQRIQLVIEYLQRDIQIEVK---------TKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGD
.|...|.....  .. .  ..| ||  . .   . . . ...|...   . . .          .. ... || |..  |.|  |  |  |.  |. |.|
NHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRD

LKTSNILVSEYFEIKLLHPLVNKIVPSFATMISQLSYGEHFDTQGIYLSPLLTKAVSQKNYQPQHNPFKSDVF
.| .|||.. . .. ..     ..  |   . .|...   .  .  | .|   . . |. ...|   .|||..
IKPQNILINNQ-GNYVYC----DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY

Kinase 5933.AA Dicty4-Unclassified 163-201 38 0.000439 9.84 In-house 111-149 (263) Show / Hide
Range on Protein: 163-201
Range on HMM: 111-149/263
Sequence Identity: 38% (15 aa)

IFTIAFSCINSLYNLQLVNLAHGDLKTSNILVSEYFEIK
|  .||.    .  |  .|. | |.| ||||.   | ||
IIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIK

Kinase 5933.AA Ciliate-C8 87-265 17 0.00044 10.92 In-house 28-238 (238) Show / Hide
Range on Protein: 87-265
Range on HMM: 28-238/238
Sequence Identity: 17% (37 aa)

DKDLVNMKQLIHITEENHKEKRTKNLIDVYEYFIQTEEKFCSS-------------VQRIQLVIEYLQRD----IQIEVKTKKLQNQRFTPQEIFTIAFS
... . |...|   |   .   .. ...|| .|. .||.                 ....  |.|    .     .   .. . ... .. |. . ||  
KIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQ

CINSLYNLQLVNLAHGDLKTSNILVSEY----FEIKLL-------HPLVNKIVPSFATMISQLSYGEHFDTQGI------YLSPLLTKAVSQKNYQPQHN
 | |. .|   |  | | | .|.||..     ..|||          .  ..  .   ..|.   |.    ...      |  | . | .| ...  .  
MIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQS--DIF

PFKSDVFTLGIIL
 .|||.. .|..|
SKKSDSYSVGLVL

Kinase 5933.AA VPS15 166-195 38 0.000533 9.88 In-house 103-133 (296) Show / Hide
Range on Protein: 166-195
Range on HMM: 103-133/296
Sequence Identity: 38% (12 aa)

IAFSCINSLYNLQLVN-LAHGDLKTSNILVS
|||   . |. ..  .   |||.|..||||.
IAFQTLCALEQCHKQGNVCHGDIKSENILVT

Kinase 5933.AA Ciliate-C3 181-205 48 0.000605 10.5 In-house 116-140 (140) Show / Hide
Range on Protein: 181-205
Range on HMM: 116-140/140
Sequence Identity: 48% (12 aa)

NLAHGDLKTSNILVSEYFEIKLLHP
|. |||.| ||||.    |||..  
NIVHGDIKFSNILINSKDEIKIIDF

Kinase 5933.AA Ciliate-B2 254-262 44 0.001445 4.14 In-house 189-197 (197) Show / Hide
Range on Protein: 254-262
Range on HMM: 189-197/197
Sequence Identity: 44% (4 aa)

FKSDVFTLG
|.||.. .|
FQSDIYSMG

Kinase 5933.AA TKL-Unique 174-202 33 0.002579 7.76 In-house 123-158 (290) Show / Hide
Range on Protein: 174-202
Range on HMM: 123-158/290
Sequence Identity: 33% (12 aa)

LYNLQLVN--LAHGDLKTSNILVSEY-----FEIKL
.|.|   .   .|.|||.||.||..      . ||.
MYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKI

Kinase 5933.AA C8 117-202 28 0.010788 5.31 In-house 84-168 (226) Show / Hide
Range on Protein: 117-202
Range on HMM: 84-168/226
Sequence Identity: 28% (26 aa)

EYFIQTEEKFCSSVQRIQLVIEYLQRDIQIEVKTKKLQNQRFTPQEIFTIAFSCINSLYNLQLVNLAHGDLKTSNILV----SEYFEIKL
|  .||||| | .|. ..|     .. ..   . .. ..| |. .. . ||   | .. .... |  | |.| .|.||    .. |||||
EKIVQTEEKSC-FVMEMELC----EQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKL

Kinase 5933.AA C8 255-265 45 0.013926 4.92 In-house 216-226 (226) Show / Hide
Range on Protein: 255-265
Range on HMM: 216-226/226
Sequence Identity: 45% (5 aa)

KSDVFTLGIIL
.||.| .|..|
QSDLFSVGLVL

Kinase 5933.AA TKL-Unique 255-268 57 0.044284 3.35 In-house 208-221 (290) Show / Hide
Range on Protein: 255-268
Range on HMM: 208-221/290
Sequence Identity: 57% (8 aa)

KSDVFTLGIILIEC
||||.  ||.|.|.
KSDVYSFGIVLWEI

MORN 5933.AA MORN 948-970 47 4e-06 26.97 Pfam 1-23 (23) Show / Hide
Range on Protein: 948-970
Range on HMM: 1-23/23
Sequence Identity: 47% (11 aa)

YEGEWCEGRMEGLGTLYYPSGSL
||||| .|.|.| |....|.|. 
YEGEWKNGKMHGHGVYTWPDGDR

MORN 5933.AA MORN 925-947 39 0.000143 21.35 Pfam 1-23 (23) Show / Hide
Range on Protein: 925-947
Range on HMM: 1-23/23
Sequence Identity: 39% (9 aa)

YIGEKLGGLRHGTGKFFYADGGY
| ||  .|..|| |.. ..||..
YEGEWKNGKMHGHGVYTWPDGDR

MORN 5933.AA MORN 946-967 36 0.000281 20.95 SMART 1-22 (22) Show / Hide
Range on Protein: 946-967
Range on HMM: 1-22/22
Sequence Identity: 36% (8 aa)

GYYEGEWCEGRMEGLGTLYYPS
  ||||| .|.. | |......
DRYEGEWHNGKRHGHGVYWWAN

MORN 5933.AA MORN 923-944 40 0.000346 20.27 SMART 1-22 (22) Show / Hide
Range on Protein: 923-944
Range on HMM: 1-22/22
Sequence Identity: 40% (9 aa)

SHYIGEKLGGLRHGTGKFFYAD
..|.||   |.||| |.. .|.
DRYEGEWHNGKRHGHGVYWWAN

MORN 5933.AA MORN 970-991 27 0.000947 17.0 SMART 1-22 (22) Show / Hide
Range on Protein: 970-991
Range on HMM: 1-22/22
Sequence Identity: 27% (6 aa)

LAYLGQWRNDQFNGKGTVYNES
  | |.|.|... |.|. .  .
DRYEGEWHNGKRHGHGVYWWAN

MORN 5933.AA MORN 972-986 40 0.006287 15.39 Pfam 1-15 (23) Show / Hide
Range on Protein: 972-986
Range on HMM: 1-15/23
Sequence Identity: 40% (6 aa)

YLGQWRNDQFNGKGT
| |.|.|....|.|.
YEGEWKNGKMHGHGV

MORN 5933.AA MORN 1014-1036 39 4.7e-05 23.11 Pfam 1-23 (23) Show / Hide
Range on Protein: 1014-1036
Range on HMM: 1-23/23
Sequence Identity: 39% (9 aa)

YEGDFKDDNKEGIGTIYLSNGDR
|||..|.. ..| |. . ..|||
YEGEWKNGKMHGHGVYTWPDGDR

MORN 5933.AA MORN 1035-1056 40 0.003105 13.14 SMART 1-22 (22) Show / Hide
Range on Protein: 1035-1056
Range on HMM: 1-22/22
Sequence Identity: 40% (9 aa)

DRFTGNFNNDFVHGQGTYFREN
|| .|.. |.  ||.|.| . |
DRYEGEWHNGKRHGHGVYWWAN

MORN 5933.AA MORN 1012-1033 27 0.00508 11.54 SMART 1-22 (22) Show / Hide
Range on Protein: 1012-1033
Range on HMM: 1-22/22
Sequence Identity: 27% (6 aa)

VKYEGDFKDDNKEGIGTIYLSN
 .|||..... . | |. . .|
DRYEGEWHNGKRHGHGVYWWAN

MORN 5933.AA MORN 1037-1052 37 0.068705 11.62 Pfam 1-16 (23) Show / Hide
Range on Protein: 1037-1052
Range on HMM: 1-16/23
Sequence Identity: 37% (6 aa)

FTGNFNNDFVHGQGTY
. |.. |.. ||.|.|
YEGEWKNGKMHGHGVY