Gene RIO1 (Sea Urchin)

RIO1

Species: Sea Urchin
Alias: SPU_004814, Spk050, RIO1
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO1

Sequence

Name Sequence Type Origin Length Description Download
RIO1.AA Protein None 737 None Fasta, JSON

Protein domain

Protein domains of RIO1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIO1.AA RIO1 1-49 79 1e-37 127.84 In-house 52-100 (225) Show / Hide 
Range on Protein: 1-49
Range on HMM: 52-100/225
Sequence Identity: 79% (39 aa)

IYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVRTWAEKEMRNLLRV
||||||| ||||.||| ||||||||.||.|||||. .||||||||| |.
IYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI
Kinase RIO1.AA RIO 1-50 56 6.2e-29 96.34 In-house 63-112 (276) Show / Hide 
Range on Protein: 1-50
Range on HMM: 63-112/276
Sequence Identity: 56% (28 aa)

IYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVRTWAEKEMRNLLRVQ
|..|... ||||.||. |||.|.|..||.|.|.|.|.||||||||. | .
IHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLWAEKEMRNMKRLY
Kinase RIO1.AA RIO1 1-51 50 1.6e-28 89.4 Pfam 19-69 (200) Show / Hide 
Range on Protein: 1-51
Range on HMM: 19-69/200
Sequence Identity: 50% (26 aa)

IYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVRTWAEKEMRNLLRVQP
||.|....||....|. ..|||||.|...|.|.|||.|||||.||| | ..
IYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYE
Kinase RIO1.AA RIO3 1-50 54 3.3e-15 47.08 In-house 66-115 (254) Show / Hide 
Range on Protein: 1-50
Range on HMM: 66-115/254
Sequence Identity: 54% (27 aa)

IYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVRTWAEKEMRNLLRVQ
..||..  ||.||||.  .|||.  . | ||||. | |||||| || |.|
VFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIHRMWAEKEMHNLARMQ
Kinase RIO1.AA RIO1 191-412 63 3.4e-152 511.91 In-house 1-225 (225) Show / Hide 
Range on Protein: 191-412
Range on HMM: 1-225/225
Sequence Identity: 63% (142 aa)

QVMDPRTRMILFKMLSRNVIYEINGCISTGKEANVYYATTKLGD--HRAIKIYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVRTWAEKEMRNLLRL
||.|||||||||||| | .| |||||||||||.||| | .  |    .|||||||||| ||||.||| ||||||||.||.|||||. .||||||||| |.
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI

HNAGVRCPEPHVLRSHVLVMDFIGIDGWPAPLLKDVNLSESKAR-ELYLECIQQVRRIYQKAKLVHADLSEFNMLYCQDKLYIIDVSQSVEHDHPSALEF
  . . |||| ...|.||.|.||| || .||.|||. ..|.... ..|.  ||  || || . ||||||||.||||  ||||.|||||||||||| .|||
YQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEF

LRKDCTNVTEYFRKNGVCTMTMREL
||.|| ||  ||.| .| ....|..
LRMDCKNVNMYFMKHNVIIFPVRDI
RIO RIO1.AA RIO 182-418 53 1.9e-135 457.19 SMART 1-253 (253) Show / Hide 
Range on Protein: 182-418
Range on HMM: 1-253/253
Sequence Identity: 53% (136 aa)

DKADRATMEQVMDPRTRMILFKMLSRNVIYEIN--GCISTGKEANVYYATT----KLGDHRAIKIYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVR
||.|.||.|.|.||||||.|.||. |..|.|||  ||||||||||||.|..    | |...|.|||.||...||....|..|.|||.|||...|.|||||
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

TWAEKEMRNLLRLHNAGVRCPEPHVLRSHVLVMDFIGIDGWPAPLLKDVNLSESKAR---ELYLECIQQVRRIYQKAKLVHADLSEFNMLYC------QD
 |||||.||| |...|||.||.|. .| |||||.||| |||||| ||||.. | ..    |.|   .  .|..|. ..||||||||.||||        .
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

KLYIIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNGVCTMT-MRELFEFVTD
|..|||.|||||.||| .||||. |..|.. .||. || .    ||.||..|.
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase RIO1.AA RIO 189-426 38 2.9e-135 455.68 In-house 1-276 (276) Show / Hide 
Range on Protein: 189-426
Range on HMM: 1-276/276
Sequence Identity: 38% (107 aa)

MEQVMDPRTRMILFKMLSRNVIYEINGCISTGKEANVYYATTKLGD-----------HRAIKIYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVRTW
.||..||.||||..||..| .......||..|||...| . .. |.            .||||..|... ||||.||. |||.|.|..||.|.|.|.|.|
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AEKEMRNLLRLHNAGVRCPEPHVLRSHVLVMDFIGIDGWPAPLLKDVNLSESKAR-ELYLECIQQVRRIYQKAKLVHADLSEFNMLYCQDKL-------Y
|||||||. ||. .|  ||||  ...||||| ||. |. |||........|.... ..|..|..  || || . |||.|..||||..  .|.       |
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

IIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNGV-CTMTMRELFEFV------------------TDPNITEDNI
.||..|.|||||| ||...|.|| .|  .| | .|  ... ||.|.||                  ........|.
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM
Kinase RIO1.AA RIO1 224-412 52 6.5e-124 386.89 Pfam 1-200 (200) Show / Hide 
Range on Protein: 224-412
Range on HMM: 1-200/200
Sequence Identity: 52% (105 aa)

NVYYATT-KLGD-HRAIKIYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMVRTWAEKEMRNLLRLHNAGVRCPEPHVLRSHVLVMDFIG-IDGWPAPL
|||.|..   |. ..|.|||.|....||....|. ..|||||.|...|.|.|||.|||||.||| |...|||.||.|. .. |||||.|||  |||||| 
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

LKDVN----LSESKARELYLECIQ-QVRRIYQKAKLVHADLSEFNMLYCQD-KLYIIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNGVC--TMTMREL
||||.    |||..|.|.| |.|. ..||.||...|||.||||.|.|.  | |..|||..|.|||||| |||||..||.|. ..||. ||   .|. ||.
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI
Kinase RIO1.AA RIO3 186-427 45 5.9e-78 262.43 In-house 1-254 (254) Show / Hide 
Range on Protein: 186-427
Range on HMM: 1-254/254
Sequence Identity: 45% (116 aa)

RATMEQVMDPRTRMILFKMLSRNVIYEINGCISTGKEANVYYAT----------TKLGD-HRAIKIYKTSILTFKDRDKYVTGEFRFRHGYCKSNPRKMV
 .| |. .||.||....||.   ..  | |||.||||. |..|           .|.     |||..||..  ||.||||.  .|||.  . | ||||. 
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

RTWAEKEMRNLLRLHNAGVRCPEPHVLRSHVLVMDFIGIDGWPAPLLKDVNLSESKARELYLECIQQVRRIYQKAKLVHADLSEFNMLYCQDKLYIIDVS
| |||||| || |.  ||. ||   .|. |.||| ||| |  ||| ||.| |   . .| | . .  .|..| .  ||||||||.|||.   |...||||
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVS

QSVEHDHPSALEFLRKDCTNVTEYFRKNGVC-TMTMRELFEFVTDPNITEDNIE
||||  ||  |||| .|| ||...|.| ||  ... ||||. |.  ||| ||  
QSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA
Kinase RIO1.AA RIO1 444-541 56 1.9e-57 196.94 In-house 127-225 (225) Show / Hide 
Range on Protein: 444-541
Range on HMM: 127-225/225
Sequence Identity: 56% (56 aa)

GGPAPLLKDVNLSESKAR-ELYLECIQQVRRIYQKAKLVHADLSEFNMLYCQDKLYIIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNGVCTMTMREL
| .||.|||. ..|.... ..|.  ||  || || . ||||||||.||||  ||||.|||||||||||| .|||||.|| ||  ||.| .| ....|..
GMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEFLRMDCKNVNMYFMKHNVIIFPVRDI
Kinase RIO1.AA RIO1 441-541 51 3.7e-57 178.7 Pfam 91-200 (200) Show / Hide 
Range on Protein: 441-541
Range on HMM: 91-200/200
Sequence Identity: 51% (57 aa)

G-DHGGPAPLLKDVN----LSESKARELYLECIQ-QVRRIYQKAKLVHADLSEFNMLYCQD-KLYIIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNGV
| . | ||| ||||.    |||..|.|.| |.|. ..||.||...|||.||||.|.|.  | |..|||..|.|||||| |||||..||.|. ..||. ||
GDKDGWPAPRLKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGV

C--TMTMREL
   .|. ||.
DERVMDFREI
Kinase RIO1.AA RIO 444-555 30 1.7e-53 181.77 In-house 135-276 (276) Show / Hide 
Range on Protein: 444-555
Range on HMM: 135-276/276
Sequence Identity: 30% (44 aa)

GG---PAPLLKDVNLSESKAR-ELYLECIQQVRRIYQKAKLVHADLSEFNMLYCQDKL-------YIIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNG
..   |||........|.... ..|..|..  || || . |||.|..||||..  .|.       |.||..|.|||||| ||...|.|| .|  .| | .
NHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFYMIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRF

V-CTMTMRELFEFV------------------TDPNITEDNI
|  ... ||.|.||                  ........|.
VYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM
Kinase RIO1.AA RIO3 446-556 49 6.2e-33 107.92 In-house 143-254 (254) Show / Hide 
Range on Protein: 446-556
Range on HMM: 143-254/254
Sequence Identity: 49% (55 aa)

PAPLLKDVNLSESKARELYLECIQQVRRIYQKAKLVHADLSEFNMLYCQDKLYIIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNGVC-TMTMRELFEF
||| ||.| |   . .| | . .  .|..| .  ||||||||.|||.   |...||||||||  ||  |||| .|| ||...|.| ||  ... ||||. 
PAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNA

VTDPNITEDNIE
|.  ||| ||  
VSGLNITADNEA
Kinase RIO1.AA RIO 420-547 22 1.6e-10 10.68 SMART 1-253 (253) Show / Hide 
Range on Protein: 420-547
Range on HMM: 1-253/253
Sequence Identity: 22% (57 aa)

N------------------------------IT---------------------------------------EDNIEEYLD-------------------
.                              |.                                       ......|..                   
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

----------EVIHKTCVS-----------------GDHGGPAPLLKDVNLSESKAR---ELYLECIQQVRRIYQKAKLVHADLSEFNMLYC------QD
          . ...  |                  || | ||| ||||.. | ..    |.|   .  .|..|. ..||||||||.||||        .
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

KLYIIDVSQSVEHDHPSALEFLRKDCTNVTEYFRKNGVCTMT-MRELFEFVTD
|..|||.|||||.||| .||||. |..|.. .||. || .    ||.||..|.
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase RIO1.AA Ciliate-C1 211-250 28 1.5e-05 9.8 In-house 1-46 (328) Show / Hide 
Range on Protein: 211-250
Range on HMM: 1-46/328
Sequence Identity: 28% (13 aa)

YEINGCISTGKEANVYYATTKLGD-HRAIKIYKT-----SILTFKD
..|   | .|. . | |.    ..   |.|. |        |||||
MKIMKTIGHGYTCKVFYCKMPNNQKVYAVKQFKNEYTSQQQLTFKD