n1191

Species: Tetrahymena
Alias: 1191, 32.m00161, n1191
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-E6

Sequence

Name Sequence Type Origin Length Description Download
n1191.AA Protein None 393 None Fasta, JSON
n1191.NA RNA None 3369 None Fasta, JSON
n1191.kin_dom Protein Kinase Domain None 65 None Fasta, JSON

Protein domain

Protein domains of n1191.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n1191.AA Ciliate-E6 84-234 36 1.3e-48 152.76 In-house 1-154 (154) Show / Hide
Range on Protein: 84-234
Range on HMM: 1-154/154
Sequence Identity: 36% (56 aa)

AKDISESLHENIIKCISHFQIQHFYLVQMEYCGQTLQDWIL-ENRRKKIDRQ-TFIMLSKQILDAASFIHSKGLVLYNFAPRNIFLQNQ-NIKIQLFGEA
.... .. |.||.| .  |||. .|...|| |. .|||||.    .|.|..  .|.  . |.. |.. .|||..|| |....|||| .. ||||  ||. 
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICDFGFQ

KEINPSNSTQFFDMQIMQNIQFYLPPEFLDNSVDAESQSIQQIWNQQADLWCIG
..|.|.  |. |  |  ||...|.|||..| | | .|   .. | | .| | ..
QCIIPNQQTKEFMAQKNQNKYHYCPPEQFDYSKDQQSKHYKVNWTQEGDIWSVC

Kinase n1191.AA Ciliate-A2 72-296 30 5e-25 83.97 In-house 37-272 (272) Show / Hide
Range on Protein: 72-296
Range on HMM: 37-272/272
Sequence Identity: 30% (72 aa)

VCQNKLADAQKLAKDISESLHENIIKCISHFQIQHFYLVQMEYC-GQTLQDWIL--ENRRKKIDRQTFIMLSKQILDAASFIHSKGLVLYNFAPRNIFL-
..|.|| .... |.  ..  |.||.|  . |||  .|  |||.|  . |||||   .| .|.| .. |. . .|||||   .|.|  || .  .||| . 
ISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIPDHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILID

QNQN-IKIQLFGEAKEINPSNSTQFFDMQIMQNIQFYLPPEFLDN---SVDAESQSIQQIWNQQADLWCIGMCLYSMAQAK-NLLYYLK-ELSYGTMYYQ
|... ||   || ||...|. ..|.|  ..     || ||| .     ... . .. | . . ..| | .| |||. . |. . .|.|. . . .   ||
QDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQCFEMNGEQNKKQQIKQTFMGDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQ

FQKSIDIDINYILLDFFQFDQIKRP-DILKQIDSFD
  .. |. .| |..   . |  |||  |.. .. . 
DYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH

Kinase n1191.AA Ciliate-E2-Unclassified 92-240 21 3.4e-16 52.7 In-house 80-263 (352) Show / Hide
Range on Protein: 92-240
Range on HMM: 80-263/352
Sequence Identity: 21% (42 aa)

HENIIKCISHFQIQHFYLVQMEYC-GQTLQDWILE---------------NRRKKIDRQTFI-----MLSKQILDAASFIHSKG-LVLYNFAPRNIFLQN
|..|.|.. .|| .      |||| |..|...| .               ..||... |  .      . .|||.. ...|.|.  . ..  | ||...|
HPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDN

Q----NIKIQLFGEAKEINPSNSTQFFD-------------MQIMQNIQF---YLPPEFLDNSVDAESQSIQQIWNQQADLWCIGMCLYSM
.    .|||  || .|... .|  . ..              ........   |..|| |..    .| .       ..| |. |..|| |
NGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA------YKCDIWSLGVILYEM

Kinase n1191.AA PKR 110-178 39 5e-11 35.61 In-house 98-168 (272) Show / Hide
Range on Protein: 110-178
Range on HMM: 98-168/272
Sequence Identity: 39% (28 aa)

VQMEYCGQ-TLQDWILENRRKKIDRQTFIMLSKQILDAASFIHSKGLVLYNFAPRNIFL-QNQNIKIQLFG
.|||.| . ||  |. . | .|.|.   . |  ||     .||||.|.     | ||||  ...|||  ||
IQMEFCDKGTLEQWMRNRRQEKVDKVLILDLYEQIVKGVDYIHSKKLIHRDLKPSNIFLVDERHIKIGDFG

Kinase n1191.AA PEK 111-174 23 1.8e-10 31.95 In-house 361-473 (655) Show / Hide
Range on Protein: 111-174
Range on HMM: 361-473/655
Sequence Identity: 23% (26 aa)

QMEYCG-QTLQDWILEN------------------------------------------RRKKIDRQTFIMLSKQILDAASFIHSKGLVLYNFAPRNIFL
|||||.  || ||| .|                                          .....|...  .. .|||..  .|||.|..     |.||||
QMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFL

-QNQN-----IKI
 ....     .||
DCDGQHHQMQVKI

S_TKc n1191.AA S_TKc 32-295 20 4.2e-10 -28.68 SMART 1-231 (231) Show / Hide
Range on Protein: 32-295
Range on HMM: 1-231/231
Sequence Identity: 20% (58 aa)

IIDSKKYEEGLSDIVYI---KQSNFQYLLKIINLQSDFEELGVVCQNKLADAQKLAKDISESLHENIIKCISHFQIQHFYLVQMEYCGQ---TLQDWILE
    .|  .|    ||    | .. .. .|||.            .. .   | | |      |.||.|.. .||  ... . ||||..   .| | | .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

NRRKK----IDRQTFIMLSKQILDAASFIHSKGLVLYNFAPRNIFLQNQNIKIQLFGEAKEINPSNSTQFFDMQIMQNIQFYLPPEFLDNSVDAESQSIQ
..|..    ..  .   . .||..|  ..||.| .     | ||.| . .|||  || |...             .    .|..|| |            
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------TTFCGTPWYMAPEVL------------

QIWNQ-QADLWCIGMCLYSMAQAKNLLYYLKELSYGTMYYQFQKSIDIDINYILLDFFQFDQIKRPDILKQID---------SF
  ..   .| | .| .|| |.  . . .      . .|. .     . .   ..   .|.|  ||| . .             |
-GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase n1191.AA Ciliate-E2 92-240 23 6.5e-09 26.72 In-house 91-289 (365) Show / Hide
Range on Protein: 92-240
Range on HMM: 91-289/365
Sequence Identity: 23% (50 aa)

HENIIKCISHFQ---IQHFYLVQMEYCGQ-TLQDWILENRRK---------KIDRQTFIMLSKQILD---------------AASFIHSKG-LVLYNFAP
| ||||.. .||    ...||| |||| . .|.|.| .|. |         ... .  . ..||||.               |  ..|||.  .  .  |
HPNIIKMYECFQEKDDNNIYLV-MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKP

RNIFLQNQNIKIQLFGEAKEINPSNSTQFFDMQIMQNIQF----------------------------YLPPEFLD------NSVDAESQSIQQIWNQQA
 ||..    |||  || .|.....|  ..  .|......|                            |..|| |       .       . |. .. ..
ENILF----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ-------QKQKGYDYKC

DLWCIGMCLYSM
|.|..|..|| |
DIWSLGVILYEM

Kinase n1191.AA PEK 109-167 37 1.8e-08 23.1 In-house 415-475 (758) Show / Hide
Range on Protein: 109-167
Range on HMM: 415-475/758
Sequence Identity: 37% (23 aa)

LVQMEYC-GQTLQDWILENRRKKIDRQTFIMLS--KQILDAASFIHSKGLVLYNFAPRNIFL
. ||..| ..|| || ..||.   .|  . ||.  .||...  .|||||.    . |.|||.
YIQMQLCRKETLKDW-MRNRCTMESRPWMHMLHWFHQICEGVNYIHSKGMIHRDLKPSNIFF

Kinase n1191.AA CMGC 81-156 15 8.6e-07 17.36 In-house 76-206 (513) Show / Hide
Range on Protein: 81-156
Range on HMM: 76-206/513
Sequence Identity: 15% (21 aa)

QKL--AKDISES--------LHEN-IIKCISHFQIQ------------------HFYLVQMEYCGQTLQDWILENR-------RKKIDRQT---------
..|  ..|. ..         |.| |.|.. .|.                    |.||| .||....| . | .|.       ... .            
KHLNKNHDP-NWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLV-FEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRP

---FIMLS------KQILDAAS--FIHSKG--LV
      ..      .||| .    ..||..   .
PHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNII

Kinase n1191.AA TKL 74-238 13 4e-06 18.17 In-house 59-280 (364) Show / Hide
Range on Protein: 74-238
Range on HMM: 59-280/364
Sequence Identity: 13% (32 aa)

QNKLADAQKLAKDISESL-------HENIIKCIS-HFQIQH-------------FYLVQMEYC-GQTLQDWILENRRKKIDRQTFIMLSKQILDAASFIH
|..  .|... . . | .       |.||....   .....             ...| |||| | .| . ..         . .. ....|  . .. |
QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIV-MEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLH

S--------KGLVLYNFAPRNIFLQNQN---------------IKIQLFGEAKEINPSNSTQFFDMQIM-----------QNIQF----YLPPEFLDNSV
|        ....  .  ..||.. . .               .||  || ......|.. .   . .|            . |     ...|| |... 
SMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQM

D-------AESQSIQQIWNQQADLWCIGMCLY
.       .| .  .   ....| .  |..|.
NYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLW

Kinase n1191.AA HRI 106-167 32 4e-06 16.65 In-house 391-466 (613) Show / Hide
Range on Protein: 106-167
Range on HMM: 391-466/613
Sequence Identity: 32% (25 aa)

HFYL-VQMEYCGQTLQDWILENRRKK----IDRQT--FIMLS--------KQILDAASFIHSKGLVLYNFAPRNIFL
|..| .||. |  .| ||| | | |.    .|.    . | .         ||.    .|| .. |     ||||||
HYMLHIQMQLCELSLWDWISE-RNKRSREYVDETECPYVMANEKVIQKIFQQIVEGMFYIHNMFIVHRDVKPRNIFL

Kinase n1191.AA TPR_1 174-187 42 23.907059 1.71 Pfam 21-34 (34) Show / Hide
Range on Protein: 174-187
Range on HMM: 21-34/34
Sequence Identity: 42% (6 aa)

IQLFGEAKEINPSN
|. . .| |.||.|
IECYQKALELNPNN

Kinase n1191.AA TPR_2 174-187 28 35.936462 1.15 Pfam 21-34 (34) Show / Hide
Range on Protein: 174-187
Range on HMM: 21-34/34
Sequence Identity: 28% (4 aa)

IQLFGEAKEINPSN
|... .| ...| |
IEYYEKALKLDPNN

TPR_1 n1191.AA TPR_1 359-392 35 2e-05 22.9 Pfam 1-34 (34) Show / Hide
Range on Protein: 359-392
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

YETYSSIGYCYYIIGDTINSEESFKKSIELNKNY
.|... .|.|||  |.    .| ..| .||| |.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR n1191.AA TPR 359-392 35 6.3e-05 23.62 SMART 1-34 (34) Show / Hide
Range on Protein: 359-392
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

YETYSSIGYCYYIIGDTINSEESFKKSIELNKNY
.|... .| |||  ||    .| ..|..||. |.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 n1191.AA TPR_2 325-358 26 0.000335 18.95 Pfam 1-34 (34) Show / Hide
Range on Protein: 325-358
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

IEDLLDEAYSFFDQKKESEAIEKFKKVIEINPNS
 | .   . . . |..  |||| ..|.....|| 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR n1191.AA TPR 325-358 26 0.00052 20.57 SMART 1-34 (34) Show / Hide
Range on Protein: 325-358
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

IEDLLDEAYSFFDQKKESEAIEKFKKVIEINPNS
.| ..  . ... ...  |||| ..|..|..|| 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 n1191.AA TPR_1 325-358 29 0.00113 16.81 Pfam 1-34 (34) Show / Hide
Range on Protein: 325-358
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

IEDLLDEAYSFFDQKKESEAIEKFKKVIEINPNS
 | .   .. .. ...  |||| ..|..|.||| 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_2 n1191.AA TPR_2 359-392 32 0.004414 14.99 Pfam 1-34 (34) Show / Hide
Range on Protein: 359-392
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

YETYSSIGYCYYIIGDTINSEESFKKSIELNKNY
 | .  .| |||  ||    .| ..|...|. |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN