Gene RhoGAP1A (Fruit Fly)
RhoGAP1A
Species: Fruit Fly
Alias: RhoGAP1A
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| RhoGAP1A.AA | Protein | None | 1403 | None | Fasta, JSON |
Protein domains of RhoGAP1A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| RhoGEF | RhoGAP1A.AA | RhoGEF | 674-857 | 25 | 1.1e-48 | 169.04 | SMART | 1-211 (211) | Show / Hide |
Range on Protein: 674-857 Range on HMM: 1-211/211 Sequence Identity: 25% (55 aa) ILSSIIQSETIYVECLNKMMQ-YKKAIHATLTTSQ-PVIREEEENTIFF-KIDELYDLHTGFLSDLKTIV--------------------SHEGGDVLIG .. ..|.| ||. |. ..| | |.. ...... |.. ..| |.||. |.|.|..|. || .|. .. ... ||.... VIQELMQTERNYVRDLHIIVQHYMKPMQKEEKCHKLPFLSPDEVNHIFGPNIEEIYEFHRRFLDELEERIEEWDCSMDWKSFRNFQIRDICDRIGDCFMK EPFRRLAEMFDLYSAFLHNYKNAIETVKK--CSANNPQFKKIVSTIVLNLQTEQ----SLTLEDLLHKPVARVQINALVFNDLLRETPNAHPDHQPLRQA . ....|||..||.. |...|... || |...||.|.| . . .. .... .|||||.| ||. |. | ....|. || .|||.. | .| W--FHAEEMFKMYSEYCNNHPYALKHLKKWMCCKKNPRFQKFCKECESHPNCRSNSEHRLTLEDFLIKPMQRITKYPLLLKEILKHTPPDHPDYEDLQKA QKIIQMFLNQFNV ..... .....| LDCMKDVAQHCNE |
|||||||||
| RhoGEF | RhoGAP1A.AA | RhoGEF | 674-857 | 28 | 2.6e-38 | 133.3 | Pfam | 1-196 (196) | Show / Hide |
Range on Protein: 674-857 Range on HMM: 1-196/196 Sequence Identity: 28% (56 aa) ILSSIIQSETIYVECLNKM-MQYKKAIHATLTTSQPVIREEEENTIFFKIDELYDLHTGFLSDLKT--IVSHE--GGDVL--IGEPF--RR-LAEMFDLY .. |||.| ||. || . |.| . . ..|.. ..| .||| |.|.|..|. ||.||. . . .. ||. | ....|..| VIQEIIQTERSYVRDLNIIIEHYMKPLRNCA--NPPILSPDEIHTIFSNIEEIYEFHQRFLEDLEERDRMECWNPPDYQCQTIGDCFMFLKHMFPFFKMY SAFLHNYKNAIETVKKCSANNPQFKKIVSTIVL--NLQTEQSLT-LEDLLHKPVARVQINALVFNDLLRETPN-AHP-DHQPLRQAQKIIQMFLNQFNV | . || .|....|||. .||.|.... . . . . ..|. |...| ||| |. | . .||. || || |...| .| . .. .... | SEYCNNYPKAMKLLKKCRKKNPKFQQFLKWCEKENDPCC-RRLDLLQSFLIKPVQRIPRYPLLLKELLKHTPPCDHPKDYEDLQKALEAMKEVASHINE |
|||||||||
| PH | RhoGAP1A.AA | PH | 873-1032 | 12 | 4.1e-10 | 40.85 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 873-1032
Range on HMM: 1-82/82
Sequence Identity: 12% (20 aa)
MVRNSFIVELVDGHRKLRHLFLFNDVIACAKYKALGRDRIDYELKWFIPLKDVSIYEEADPAVELKESSPANISQVKRNLRSVRDQLAMEVANSGSGAFR
... .. . ..| |...||||.. . | | ..| .|||.|....| .
VIKEGWLYKKSK-RWKKRWFVLFNDCLYYYKDK---------KPKGSIPLSDCTVRE-P-----------------------------------------
SGDKYRRKLADLESQLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWIDSILSLKQKC
. .. .. |..|. .|. |...|...| .. ...
---------------------CFEIHH-DR----TYYFQCESEEEMQEWMQAIQKAIHNN
|
|||||||||
| PH | RhoGAP1A.AA | PH | 873-1030 | 12 | 1.4e-05 | 22.82 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 873-1030
Range on HMM: 1-92/92
Sequence Identity: 12% (20 aa)
MVRNSFIVELV-DGHRKLRHLFLFNDVIACAKYKALGRDRIDYELKWFIPLKDVSIYEEADPAVELKESSPANISQVKRNLRSVRDQLAMEVANSGSGAF
.. .. .. . .| |...|||... . | . |..| |||.|..... |.
VIKEGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDK-------YRPKGSIPLSDCQVTKVPDN--------------------------------------
RSGDKYRRKLADLESQLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWIDSILSLKQ
. .... . . .|..|. .|. |...|...| |.
--------------------KRPHCFQIRT-DR-RTYYFQAESEEEMNDWMQAIQSACR
|
|||||||||
| RhoGAP | RhoGAP1A.AA | RhoGAP | 1218-1374 | 35 | 5.1e-66 | 225.97 | Pfam | 1-156 (156) | Show / Hide |
Range on Protein: 1218-1374 Range on HMM: 1-156/156 Sequence Identity: 35% (55 aa) PFIIGACIREVERRGMLEVGCYRVSGSASDLAKLKKAFESDAYEAEQLLREVDIHSVTGILKTFLRELPEALFTDQLYPRFFDTFSAFSNNNESTRINEL |.|. ||...|..|. ..| |||||..| . .|..||..... ........|.|.|...||...||||| |||..||..|. . |.....|..||... PMIVRKCIEYIEQHGLDTEGIYRVSGNKSRIKELREAFDRGPDVDLNDWEWHDVHDVASVLKQYFRELPEPLFTFELYEEFI-EAMAAKIEDEEERIEAM LKVFEELPQANKASITSILDHLIRVHEKETDNKMSLHNLAMVFGPTLLRPGQTQVKQ .... ||..| . ...|| ||.. . .|||. ||||..|||.|..| ... .. RELIRKLPPPNYDTLRYLMRHLHRVAQHSDVNKMNAHNLAICFGPNLFWPPDDDSMD |
|||||||||
| RhoGAP | RhoGAP1A.AA | RhoGAP | 1215-1395 | 28 | 5.5e-63 | 216.47 | SMART | 1-193 (193) | Show / Hide |
Range on Protein: 1215-1395
Range on HMM: 1-193/193
Sequence Identity: 28% (58 aa)
RDIPFIIGACIREVERRGMLEVGCYRVSGSASDLAKLKKAFESDAYEA-----------EQLLREVDIHSVTGILKTFLRELPEALFTDQLYPRFFDTFS
..|| |. ||...|..|| ..| ||..|..| . .|..||... . . ...| |.|.|.|.||...||||| |.|..||..| . .
SHIPIIVRKCIEYIEKHGMDTEGIYRKCGNQSRIQELRNAFDRGPD-DLCSTDNYITHEFNDWEEWDVHDVAGVLKQYFRELPEPLITFELYEEFIEAMK
A-----------FSNNNESTRINELLKVFEELPQANKASITSILDHLIRVHEKETDNKMSLHNLAMVFGPTLLRPGQTQVKQKDPLAASTVDVMAQAGIL
....|..|| .|......||..... .. || ||.|.. |||..||||..|||||..| ... .... . |
CYQIEQTSRKQWNHSEDEEERIHALHQLISQLPPCHRNTLRYLM-HLNRVAEHSDVNKMNAHNLAICFGPTLFWPP--------MMDMRHQNKCVEFLIE
YCF
...
HYD
|
|||||||||