Gene HisK_a (S.moellendorffii)

HisK_a

Species: S.moellendorffii
Alias: HisK_a
External Links:
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
HisK_a.AA Protein None 799 None Fasta, JSON
HisK_a.NA RNA None 2397 None Fasta, JSON

Protein domain

Protein domains of HisK_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA HisK_a.AA HisKA 327-392 33 4e-22 80.75 SMART 1-89 (89) Show / Hide 
Range on Protein: 327-392
Range on HMM: 1-89/89
Sequence Identity: 33% (30 aa)

KAKQLLATMSHEIRSPLSGVVSMAEILAA----------TNLDPEQ-------------QNLVDIMVSSGDLVMQLINDILDLSKVESG
   |.||.||||.| ||...  .||.| .          |.|||||             . ..... ...|   .||||.||||. |.|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA HisK_a.AA HisKA 327-392 40 4.7e-22 79.82 Pfam 1-69 (69) Show / Hide 
Range on Protein: 327-392
Range on HMM: 1-69/69
Sequence Identity: 40% (28 aa)

KAKQLLATMSHEIRSPLSGVVSMAEILAA-TNLDPEQ--QNLVDIMVSSGDLVMQLINDILDLSKVESG
  .|.||.||||.| ||...  .||.| . |.|||||  . ..... ....   .||||.||.|. |.|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HATPase_c HisK_a.AA HATPase_c 439-592 28 1.9e-39 139.49 Pfam 1-120 (120) Show / Hide 
Range on Protein: 439-592
Range on HMM: 1-120/120
Sequence Identity: 28% (46 aa)

ADVLRVRQILTNLVSNAIKFTRH-GSVRVEIEIGNKKLPHKQNGSIVDSNELQTPCSSSITSPATTTSTVPQWVNNDTVWLECRIVDTGIGIPD------
.| .|..|...|||.||||.|.  | ..|...  .                                            ... .. |.|.|||.      
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-------------------------------------------DHVRITVEDNGPGIPPEMHSIA

TALPFLFTKYMQVSE-THARKYGG--TGLGLAICKQLVELMGGKLKVNSEENKGSTFMFTLPCK
  .| .| .. ....  . |||||  |||||.||...||..||.. |.||...|.|| |||| .
EDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE
HATPase_c HisK_a.AA HATPase_c 439-593 24 4.8e-38 133.62 SMART 1-130 (130) Show / Hide 
Range on Protein: 439-593
Range on HMM: 1-130/130
Sequence Identity: 24% (45 aa)

ADVLRVRQILTNLVSNAIKFTRH--------------GSVRVEIEIGNKKLPHKQNGSIVDSNELQTPCSSSITSPATTTSTVPQWVNNDTVWLECRIVD
.|  |.||.|.||..||||.| .              | ..|...                                                 . .. |
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------RITVED

TGIGIPD------TALPFLFTKYMQVSE--------THARKYGG--TGLGLAICKQLVELMGGKLKVNSEENKGSTFMFTLPCKL
.|.|||.        .| .| .. ....         ..|||||  |||||.|||..||..||...|.      .|| |||| ..
NGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER
Kinase HisK_a.AA HisK 439-592 22 2.9e-28 98.57 In-house 1-164 (164) Show / Hide 
Range on Protein: 439-592
Range on HMM: 1-164/164
Sequence Identity: 22% (45 aa)

ADVLRVRQILTNLVSNAIKFTRHG------SVRVEIE-IGNKKLPHKQNGSIVDSNELQTPCSSSITSPATTTSTVPQWVNNDTVWLEC-----------
 |  |..||| ||.|||.||| .|      ......| | ...   | | |                                   ...           
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN-IKYN-S-----------------------------------IFIQKIQENMVQEQ

---------RIVDTGIGIPDTALPFLFTKYMQV---------SETHARK---YGGTGLGLAICKQLVELMG--------GKLKVNSEENKGSTFMFTLPC
          . |||.|.|.  .  .| .. ..         .  | .|     | ||||.||..|....|        ....| ||..||||| | . .
LQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYN

K
.
N
Response_reg HisK_a.AA Response_reg 689-753 36 6.9e-18 66.63 Pfam 1-68 (115) Show / Hide 
Range on Protein: 689-753
Range on HMM: 1-68/115
Sequence Identity: 36% (25 aa)

VLLAEDNKVNIMVAQSMLR-RMGL-EATVVNDGAEAVEAIKRDYFDLILMDVIMPVMDGLEATRLI-R
||...|. .. .. . .|. ..|. ..... ||.||.| ...  .|||.||. || |||||..| | |
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRR
REC HisK_a.AA REC 687-799 16 5.2e-13 50.47 SMART 1-150 (150) Show / Hide 
Range on Protein: 687-799
Range on HMM: 1-150/150
Sequence Identity: 16% (28 aa)

LKVLLAEDN----KVNIMVAQ------SMLRRMGLE--------ATVVNDGA-------EAVEAIKRDY-------------FDLILMDVIMP-------
...|...|.     |. .. .       .|...| |        .... ||.       ||.|....               .|||.||. ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMDGLEATRLIRDTQGNRDGQGKRSTIIAVSDHICSSFSIVRDKLFS-----------DQSIAAFSVLA
 |||.|..| ||              ||...     ... . |.              . ..  .    
GMDGIELCRRIR-------------PIIMLT-----AHDDEEDRVRALEAGADDYITKPFDPEELLARI