Gene HisK_m (S.moellendorffii)
HisK_m
Species: S.moellendorffii
Alias: HisK_m
External Links:
Annotation:
Sequence
Protein domains of HisK_m.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| HisKA | HisK_m.AA | HisKA | 37-102 | 39 | 7.9e-27 | 96.37 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 37-102 Range on HMM: 1-89/89 Sequence Identity: 39% (35 aa) AKSEFLANMSHEIRTPLNGIINCTELCLD----------TRTSLEQ-------------QEYLDLVRFSAKHLLRIITDILDFSKIEAG ||..||||||||.||||..|. .||..| | . || .|||. .. .|....|.| |.||.|.|||| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
|||||||||
| HisKA | HisK_m.AA | HisKA | 37-102 | 52 | 1.9e-26 | 95.16 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 37-102 Range on HMM: 1-69/69 Sequence Identity: 52% (36 aa) AKSEFLANMSHEIRTPLNGIINCTELCLD-TRTSLEQ--QEYLDLVRFSAKHLLRIITDILDFSKIEAG ||..||||||||.||||..|. .||..| | . || .|||. .. .|....|.| |.||||.|||| AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
|||||||||
| HATPase_c | HisK_m.AA | HATPase_c | 149-264 | 34 | 9.5e-32 | 112.73 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 149-264 Range on HMM: 1-120/120 Sequence Identity: 34% (43 aa) GDPGRLFQIFVNLIGNSIKFTEK-GEVVVSAQVHNIYRDRVELIFAVKDTGVGIPK------AKQSLLFQAFSQVDSSTTRWLYGG--TGLGLVISSKLA ||| || |.. ||..|.||.|.. |.. |.. . .... |.|.|.|||. ... .|..| ..|.. . ||| ||||| |. ... GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIV AAMAGKMWVESE-GKGSIFYFTAAFD .. |..||||| |.|. | || .. EQHGGTIWVESEPGGGTTFTFTLPLE |
|||||||||
| HATPase_c | HisK_m.AA | HATPase_c | 149-265 | 27 | 1.3e-31 | 112.23 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 149-265 Range on HMM: 1-130/130 Sequence Identity: 27% (40 aa) GDPGRLFQIFVNLIGNSIKFTEK--------------GEVVVSAQVHNIYRDRVELIFAVKDTGVGIPK------AKQSLLFQAFSQVDS--------ST ||| || |.. ||..|.||.|.. |.. |.. .. |.|.|.|||. ... .|..| ..|. |. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-----------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSR TRWLYGG-TGLGLVISSKLAAAMAGKMWVESEGKGSIFYFTAAFDI .| || ||||| |. ... .. |..||| . |.|| . SRKYGGGLTGLGLSICKRIVEQHGGTIWVE-----TTFTFTLPLER |
|||||||||
| Kinase | HisK_m.AA | HisK | 149-259 | 26 | 4.3e-23 | 79.93 | In-house | 1-159 (164) | Show / Hide |
Range on Protein: 149-259
Range on HMM: 1-159/164
Sequence Identity: 26% (42 aa)
GDPGRLFQIFVNLIGNSIKFTEKG------EVVVSAQVHN-----------IYRDRVE-----------LIFAVKDTGVGIPKAKQSLLFQAFSQ-----
|| |. || .|||.|..|||.|| . .... | | . . . . |.|||.|.|. .| .|..|..
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH
-----VDSSTTRWL-YGGTGLGLVISSKLAAAMA--------GKMWVESE-GKGSIFYF
.. . | ||||.|. .|| . .. |.|| ||||.|.|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSF
|
|||||||||
| Response_reg | HisK_m.AA | Response_reg | 285-301 | 35 | 9.583761 | 1.65 | Pfam | 1-17 (115) | Show / Hide |
Range on Protein: 285-301 Range on HMM: 1-17/115 Sequence Identity: 35% (6 aa) ALVVDDHITSLGILAKL |.|||| . . .|... VLIVDDHPLMREGLRQI |
|||||||||
| REC | HisK_m.AA | REC | 311-427 | 24 | 8.2e-39 | 136.18 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 311-427 Range on HMM: 1-150/150 Sequence Identity: 24% (39 aa) LKILVAEDN----IVNQRVAV------SLLRKWGHS--------AVIACNGA-------EAIEKASQE-------------TFDLILMDVQMP------- ..||...|. |.... ||.|.|. ...| .|. ||.|.. .. .|||.||..|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG ICDGFQATTKIREMEKNKGMSSTPIVAMTAHAMFGDGDRCIAAGMDGYISKPLNAKKLQELL ||.... .|| ||...|||.. | |...||.|.||.|| ... |.. . GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
|||||||||
| Response_reg | HisK_m.AA | Response_reg | 313-428 | 29 | 4.2e-30 | 110.41 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 313-428 Range on HMM: 1-115/115 Sequence Identity: 29% (35 aa) ILVAEDNIVNQRVAVSLLR-KWGH-SAVIACNGAEAIEKASQETFDLILMDVQMPICDGFQATTKI-REME-KNKGMSSTPIVAMTAHAMFGDGDRCIAA .|...|. ..... . .|. |.| .. | .|.||.|.. ....|||.||..|| .||......| |. . . |||...|||.. | ... | VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDEDDAVEALQA GMDGYISKPLNAKKLQELLV |...||.|| . .| . . GANDYITKPFDPDELHAAIR |
|||||||||