Gene HisK_l-1 (S.moellendorffii)

HisK_l-1

Species: S.moellendorffii
Alias: HisK_l-1
External Links:
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
HisK_l-1.AA Protein None 749 None Fasta, JSON
HisK_l-1.NA RNA None 2250 None Fasta, JSON

Protein domain

Protein domains of HisK_l-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
GAF HisK_l-1.AA GAF 161-310 19 6.2e-18 65.4 Pfam 1-160 (160) Show / Hide 
Range on Protein: 161-310
Range on HMM: 1-160/160
Sequence Identity: 19% (32 aa)

VRDTILNTTLVELGKALALEECAL--WMPSRDGLELHLCRTLGSTNP--GRVTVPVHHPSIQPVFCTHRARNIPATSPVAAIRPRAGKYLP-GEVVAVRV
 ...|| |.. ||...| .. |..  ... .||.||..... |.. .  ... .|  .. .. |||| .. ..| ..  .  | ..  .    |..   .
DLEEILQTIMQELRQLLGCDRCMIYFFLWDEDGWELYWVAHWGWSDQPQQAR-LPM-GGIWGEVFCTCNPIVVPDVC-DPRFR-WPCVDEDRPEHHHCHC

PLLH----VENFNISYW---PEGG-DV-PYALLVLMLPSDSARTWHLHELE--LVEAVAGQVAVAL
....      .. ..     . |. .    ..|..  . .  |.|. |.||  |....| |.|.|.
HYMRHMHHGIRSCLCVPIFDIIGQPGQQVWGVLCCHHC-P-PRHWTEHDLECFLLQMFADQIAIAI
GAF HisK_l-1.AA GAF 161-320 16 6.5e-11 43.49 SMART 1-142 (142) Show / Hide 
Range on Protein: 161-320
Range on HMM: 1-142/142
Sequence Identity: 16% (27 aa)

VRDTILNTTLVELGKALALEECALWMPSR-----DGLELHLCRTLGSTNPGRVTVPVHHPSIQPVFCTHRARNIPATSPVA---AIRPRAGKYLPGEVVA
  ..|..|.. |... | .. |.... ..      .|..|. .        . ...   . .. |. |.| .||| ...       ....  |    . .
DLEEICQTIVEEVHQFLQMDRCMIYLFDERQNDHGQLWCHASD--------HFPPD---GICGWVWRTGRPVNIPDVHHDPHFFCWKDWL-RYQ--IRSF

VRVPLLHVENFNISYWPEGGDVPYALLVLMLPSDSARTWHLHELELVEAVAGQVAVALSHAAILEESI
. ||..              .   ..|..    ...| |. ...|.....| |||.|...|...|.. 
LCVPIMND-----------DGQVWGVLCAHHC-HQPRHWTEEDEEFLQMIANQVAIAIQQAQLYEQLQ
HisKA HisK_l-1.AA HisKA 346-411 42 5e-18 65.79 Pfam 1-69 (69) Show / Hide 
Range on Protein: 346-411
Range on HMM: 1-69/69
Sequence Identity: 42% (29 aa)

SRNDFLAVMDREMRTPMSTIIAASSHLQD-TSLSQEQ--RAMVDTILNSSNLLATLINDVLDVSRLEDG
....||| |  |.|||...|..... ||| | |. ||  | ...||..... .  ||||.|| ||.| |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA HisK_l-1.AA HisKA 346-411 32 1e-17 66.07 SMART 1-89 (89) Show / Hide 
Range on Protein: 346-411
Range on HMM: 1-89/89
Sequence Identity: 32% (29 aa)

SRNDFLAVMDREMRTPMSTIIAASSHLQD----------TSLSQEQ-------------RAMVDTILNSSNLLATLINDVLDVSRLEDG
....||| |  |.|||...|..... |||          | |. ||             | ...||..... .  ||||.|| ||.| |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HATPase_c HisK_l-1.AA HATPase_c 458-585 31 1.3e-33 119.22 Pfam 1-120 (120) Show / Hide 
Range on Protein: 458-585
Range on HMM: 1-120/120
Sequence Identity: 31% (44 aa)

GDDKRFVQIALNIVGNAVKFTKE-GSVSITVRLEKPESFQASDYVVPSEKHCYIRVQVQDTGIGVNP------QDIPKLFNKFIQAPA-VSSRKQVG--T
||  |..|. .|.|.||.|.|.| | ....|. ..                 ..|..|.|.|.|. |      .|||..| .| .. .  . ||  |  |
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD----------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLT

GLGLAISKRLVSLMDGNIWFESEGLNRGCTVSYVVRLA
||||.|..|.| ...| ||.|||  ..|.|..  . |.
GLGLYICRRIVEQHGGTIWVESEP-GGGTTFTFTLPLE
HATPase_c HisK_l-1.AA HATPase_c 458-586 28 3.5e-32 114.17 SMART 1-130 (130) Show / Hide 
Range on Protein: 458-586
Range on HMM: 1-130/130
Sequence Identity: 28% (45 aa)

GDDKRFVQIALNIVGNAVKFTKE------------GSVSITVRLEKPESFQASDYVVPSEKHCYIRVQVQDTGIGVNP------QDIPKLFNKFIQAPA-
|| .|. |. .|...||.|.|.|            |   ||||..                    |..|.|.|.|. |      .|||..| .| ..   
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDS

-------VSSRKQVG--TGLGLAISKRLVSLMDGNIWFESEGLNRGCTVSYVVRLAI
        .|||  |  |||||.|.||.| .. | ||.|       .|..  ..|..
PSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE-------TTFTFTLPLER
Kinase HisK_l-1.AA HisK 458-585 22 1.1e-21 74.8 In-house 1-164 (164) Show / Hide 
Range on Protein: 458-585
Range on HMM: 1-164/164
Sequence Identity: 22% (38 aa)

GDDKRFVQIALNIVGNAVKFTKEG----SVSITVRLEKPE-------------------SFQASDYVVPSEKHCYIRVQVQDTGIGVNPQDIPKLFNKFI
 |  |. || .|...||.|||..|    ...|.. .|. .                   . |   .  . ..  .|...|||||.| ..... |.|..| 
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMV-Q---E--QLQQKNLIQISVQDTGCGMPEEQQKKIFKMFG

------------QAPAVSSRKQVGTGLGLAISKRLVSLMD--------GNIWFESEGLNRGCTVSYVVRLA
            .     . .| | ||||.|...|. ..         ..| ..||  . |.| | ...  
NIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSE-VGKGSTFSFYIYNN
REC HisK_l-1.AA REC 613-729 18 1.5e-18 68.84 SMART 1-150 (150) Show / Hide 
Range on Protein: 613-729
Range on HMM: 1-150/150
Sequence Identity: 18% (30 aa)

LRVLVMDAN----GANRMVTR------GLLLRLGCD--------AFAVGSPR-------ECLQLLAQPG-----------RSFRLVLVDVYMA-------
.|.|. | .     ..|.. |       || ..|..        . .. . .       | |.||..               . |...|. |        
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

ESDGFEVAVKIQDMFKRHERPLVVALTAAHDRQTSERCSSIGMDGVIFKPISLEKMRSAL
. ||.|.. .|.          ...|||  | .. .|.   |.|. | ||...| .. ..
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg HisK_l-1.AA Response_reg 615-730 22 6.8e-14 52.34 Pfam 1-115 (115) Show / Hide 
Range on Protein: 615-730
Range on HMM: 1-115/115
Sequence Identity: 22% (26 aa)

VLVMDANGANRMVTRGLLL-RLGC-DAFAVGSPRECLQLLAQPGRSFRLVLVDVYMAESDGFEVAVKIQDMFKRHERPLVVALTAAHDRQTSERCSSIGM
||. | . ..|.. | .|  . |. .. .. ...|.|... | .. . |.. |. | . ||.|.. .|.   . |  . ....||  | .. ...   |.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-QEHH-PDLIIMDINMPGMDGLELCRRIRRQHP-HPQTPIIMCTAHGDEDDAVEALQAGA

DGVIFKPISLEKMRSALA
.. |.||....... |..
NDYITKPFDPDELHAAIR