Gene RIO2-2 (S.moellendorffii)

RIO2-2

Species: S.moellendorffii
Alias: RIO2-2
External Links:
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO2

Sequence

Name Sequence Type Origin Length Description Download
RIO2-2.AA Protein None 331 None Fasta, JSON
RIO2-2.NA RNA None 993 None Fasta, JSON

Protein domain

Protein domains of RIO2-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIO2-2.AA RIO2 71-324 51 9.40000000001e-136 457.29 In-house 1-260 (260) Show / Hide 
Range on Protein: 71-324
Range on HMM: 1-260/260
Sequence Identity: 51% (134 aa)

YRLTNLGYDFLAIKTMVNRGLIVGVGRQIGVGKESDIFEVVAEDGQTLALKLHRLGRTSFRAVKSKRDYLKHRSSFNWLYLSRLAALKEFAFMKALHEHG
||||| |||.||.||.  |  .  || |.||||||||. .. |.|.  ..|.||||||||. .| .|||.||| . .|.|||||.| ||..||..|.. .
YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN

FPTPKAVDWNRHCVLMTLVPGYPLVQVKELKNPALVFDTVISLIVRLAEHGLIHCDFNEFNLLIDDDEK------VTMIDFPQMVSISHRNAESYFDRDV
||.|| .| ||| | | |. |||. | .. .||. |.| .  .|||||.|||||||||||||.|||  .      ..|||||||||..|.||. ||||||
FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV

DCIYKFFLKRFNYVPGGNARTLQGIDNNVDEDDTRPDFENLARTAGALDKELAASGFTHQ
||| .|| ||||| |      |             |||    .    || |  ||||. .
DCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQASGFNKK
Kinase RIO2-2.AA RIO 71-277 41 9.1e-108 364.33 In-house 1-236 (276) Show / Hide 
Range on Protein: 71-277
Range on HMM: 1-236/276
Sequence Identity: 41% (97 aa)

YRLTNLGYDFLAIKTMVNRGLIVGVGRQIGVGKESDIFEVVAEDGQ-----------TLALKLHRLGRTSFRAVKSKRD---YLKHRSS-FNWLYLSRLA
|..|| .|. .....||||| .  || .|||||||||.... |.|.             |.|.||.|||||. .| .||   |.||| .  ||.|..||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

ALKEFAFMKALHEHGFPTPKAVDWNRHCVLMTLVPG-------YPLVQVKELKNPALVFDTVISLIVRLAEHG-LIHCDFNEFNLLIDDDEK------VT
| ||...||.|.. |||.|. .| .|| . | .  .       ||..| .|..|.. |..... ...||..|. |.||||||||....|. .      ..
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

MIDFPQMVSISHRNAESYFDRDVDCIYKFFLKRFNY
||||||||...| .|. ||.||..|.  || |||.|
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVY
Kinase RIO2-2.AA RIO1 106-279 31 4.4e-79 247.08 Pfam 1-195 (200) Show / Hide 
Range on Protein: 106-279
Range on HMM: 1-195/200
Sequence Identity: 31% (62 aa)

DIFEVVA-EDGQ-TLALKLHRLGRTSFRAVKSKRDYLKH----RSSFNWLYLSRLAALKEFAFMKALHEHGFPTPKAVDWNRHCVLMTLVP---GYPLVQ
....... |||.  .|.|..|.|.|.|. .| .||| ..    ..  ||.|..|..| |||...|...|.|.| ||..|||||...| ..    |.|. .
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

VKELK--------NPALVFDTVIS--LIVRLAEHGLIHCDFNEFNLLIDDDEKVTMIDFPQMVSISHRNAESYFDRDVDCIYKFFLKRFNY--VP
.|..         ... ..| .|   ......|.||.|.|..|.|.|..||.|...||.||.|...|..|.....||...| .|| ... .  |.
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVM
RIO RIO2-2.AA RIO 64-291 22 2.4e-58 201.04 SMART 1-253 (253) Show / Hide 
Range on Protein: 64-291
Range on HMM: 1-253/253
Sequence Identity: 22% (58 aa)

DSTKYDGYRLTNLGYDFLAIKTMVNRGLIVGVG--RQIGVGKESDIFEVVA----EDGQTLALKLHRLGRTSFRAVKSKRD-YLKHR---SSFNWLYLSR
|. .|..|...  ... .....||||| |  ..  ..|..|||.... ...    ..|   | | .|...|.|. ..  .. . . .   .  ||....|
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

LAALKEFAFMKALHEHGFPTPKAVDWNRHCVLMTLVPG--YPLVQVKELKNPA-------LVFDTVISLIVRLAEHG-LIHCDFNEFNLLID-----DDE
|.| ||| ... ..|.|.| ||...|.|| ..| .. .  .|  ..|....          ....... ...... . |.|.|..|.|.|..     .|.
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

KVTMIDFPQMVSISHRNAESYFDRDVDCIYKFFLKRFNYVPGGNARTLQGIDN
|| .||..| |...|. ..... ||...| .|| ..  ...    .  ..|  
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Rio2_N RIO2-2.AA Rio2_N 8-89 58 1e-50 173.48 Pfam 1-84 (84) Show / Hide 
Range on Protein: 8-89
Range on HMM: 1-84/84
Sequence Identity: 58% (49 aa)

LRYLSKDEFRVLTAVEMGMKNHEIVPAELIDRIAGLK-TGGAYKNIRTLLRHKLVHH-DSTKYDGYRLTNLGYDFLAIKTMVNR
.|||||..|||||||||||.|||.|| ||| .|..|.  || .. .. |..|||..| . .||||||||..|||.||..|.|.|
MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR
Kinase RIO2-2.AA Ciliate-C1 93-121 23 7e-06 10.64 In-house 1-30 (328) Show / Hide 
Range on Protein: 93-121
Range on HMM: 1-30/328
Sequence Identity: 23% (7 aa)

VGVGRQIGVGKESDIFEVVAEDGQ-TLALK
   ...|| |. .. | . ....|  .|.|
MKIMKTIGHGYTCKVFYCKMPNNQKVYAVK
Kinase RIO2-2.AA APH 95-178 12 7.3e-05 17.46 Pfam 1-62 (248) Show / Hide 
Range on Protein: 95-178
Range on HMM: 1-62/248
Sequence Identity: 12% (11 aa)

VGRQIGVGKESDIFEVVAEDGQ-TLALKLHRLGRTSFRAVKSKRDYLKHRSSFNWLYLSRLAALKEFAFMKALHEHGF--PTPKAVD
 .|.|. | ... . ....| . .. |..                   ....      .. .. .|......|..||.  |.|. ..
WWRPISGGWSNRTYYRTTDD-RPRYVLRR-------------------YPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLW
Kinase RIO2-2.AA Ciliate-C3 217-245 37 0.000121 13.01 In-house 112-140 (140) Show / Hide 
Range on Protein: 217-245
Range on HMM: 112-140/140
Sequence Identity: 37% (11 aa)

LAEHGLIHCDFNEFNLLIDDDEKVTMIDF
| || ..| |    |.||   ... .|||
LHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase RIO2-2.AA RIO3 81-273 24 0.000621 8.4 In-house 14-227 (254) Show / Hide 
Range on Protein: 81-273
Range on HMM: 14-227/254
Sequence Identity: 24% (53 aa)

LAIKTMVNRGLIVGVGRQIGVGKESDIFEVV-------AEDGQTLA----LKLHRLGRTSFRA----VKSKRDYLKHRSSFNWLYLSRLAALKEFAFMKA
| .  ||| |..  .   |  |||| .|           || . .     .|. .     |.     .|    .    | .|   . |. | ||   .  
LLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIHRMWAEKEMHNLAR

LHEHGFPTPKAVDWNRHCVLMTLVPGYPLVQVKELKNPAL--------VFDTVISLIVRLAEHGLIHCDFNEFNLLIDDDEKVTMIDFPQMVSISHRNAE
.   | | |  |   .| ..|... |.  |    ||.  |         ..|.  .     |  |.| |. |.|.|     || .||  | |  .|    
MQRAGIPCPTVVLLKKHILVMSFI-GHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLW-HAGKVWLIDVSQSVEPTHPHGL

SYFDRDVDCIYKFFLK
 .. ||.  . .|| |
EFLFRDCRNVSQFFQK
Kinase RIO2-2.AA APH 221-245 31 0.003988 11.54 Pfam 171-199 (248) Show / Hide 
Range on Protein: 221-245
Range on HMM: 171-199/248
Sequence Identity: 31% (9 aa)

GLIHCDFNEFNLLID---DDEKV-TMIDF
...|.||.  |...|   |...|   ||.
CWCHGDFHPGNVMWDPRPDGGRVTGVIDW