PDGFRb_Hsap MRLPGAMPALALKGELLLLSLLLL--------------L------------EPQI-----
PDGFRa_Hsap MGTS--HPA------FLVLGCLLT-------GLS---LI------------LCQL-----
KIT_Hsap MRGA--RGAWD---FLCVLLLLLRVQ----TGSSQPSVS------------PGEP-----
FMS_Hsap MGPG--V-------L--LLLLVATAW----HGQG--------------------------
FLT3_Hsap MPAL--ARDGG---QLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPM
PDGFRb_Mmus MGLPGVIPALVLRGQL-LLSVLWL--------------L------------GPQT-----
PDGFRa_Mmus MGTS--HQV------FLVLSCLLT-------GPG---LI------------SCQL-----
KIT_Mmus MRGA--RGAWD---LLCVLLVLLRGQ----TATSQPSAS------------PGEP-----
FMS_Mmus MELG--P-------P--LVLLLATVW----HGQG--------------------------
FLT3_Mmus MRAL--AQRSD--RRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRM
* :: .
PDGFRb_Hsap ---------------SQGLVVTPPGPELVLNVSSTFVLTCS--GSAPVVWERMSQE-PPQ
PDGFRa_Hsap ---------------S-LPSILPNENEKVVQLNSSFSLRCF--GESEVSWQYPMSE-EES
KIT_Hsap ---------------S-PPSIHPGKSDLIVRVGDEIRLLCT--DPGFVKWTFEIL----D
FMS_Hsap -----------------IPVIEPSVPELVVKPGATVTLRCV--GNGSVEWDGPPSP-HWT
FLT3_Hsap VSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQ
PDGFRb_Mmus ---------------SRGLVITPPGPEFVLNISSTFVLTCS--GSAPVMWEQMSQV-PWQ
PDGFRa_Mmus ---------------L-LPSILPNENEKIVQLNSSFSLRCV--GESEVSWQHPMSE-EDD
KIT_Mmus ---------------S-PPSIHPAQSELIVEAGDTLSLTCI--DPDFVRWTFKTYF---N
FMS_Mmus -----------------APVIEPSGPELVVEPGETVTLRCV--SNGSVEWDGPISP-YWT
FLT3_Mmus VRGSPEDLQCAPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQ
. : . . : . *
PDGFRb_Hsap ---E--MAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLET-DERKRLYIFVPDPTV
PDGFRa_Hsap SDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDV
KIT_Hsap E-----TNENK----QNEWITEKAEATNTGKYTCTNKH-------GLSNSIYVFVRDPAK
FMS_Hsap L-----YSDGS----SSILSTNNATFQNTGTYRCTEPGD---P-LGGSAAIHLYVKDPAR
FLT3_Hsap PHFDLQ----NRGV-VSM-VILKMTETQAGEYLLFIQSEA----TNYTILFTVSIRNT-L
PDGFRb_Mmus ---E--AAMNQDGTFSSVLTLTNVTGGDTGEYFCVYNNSLGPEL-SERKRIYIFVPDPTM
PDGFRa_Mmus PNVEIRSEENNSGLFVTVLEVVNASAAHTGWYTCYYNHTQTDESEIEGRHIYIYVPDPDM
KIT_Mmus E-----MVENK----KNEWIQEKAEATRTGTYTCSNSN-------GLTSSIYVFVRDPAK
FMS_Mmus L-----DPESP----GSTLTTRNATFKNTGTYRCTELED---P-MAGSTTIHLYVKDPAH
FLT3_Mmus PHFDLQ----NRGI-VSM-AILNVTETQAGEYLLHIQSEA----ANYTVLFTVNVRDT-Q
. . :* * : : : :.
PDGFRb_Hsap GFLPNDAEELFIFL-TEITEITIPCRVTDPQLV--VTLHEKKG-DVALP---VPYDHQRG
PDGFRa_Hsap AFVPLGMTDYLVIV-EDDDSAIIPCRTTDPETP--VTLHNSEG-VV--P---ASYDSRQG
KIT_Hsap LFL-V---DRSLYG-KEDNDTLVRCPLTDPEVT-NYSLKGCQGKPLPKDLR-FIPDPKAG
FMS_Hsap PWNVL---AQEVVV-FEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTN-YSFSPWHG
FLT3_Hsap LYT-L---RRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKV
PDGFRb_Mmus GFLPMDSEDLFIFV-TDVTETTIPCRVTDPQLE--VTLHEKKV-DIPLH---VPYDHQRG
PDGFRa_Mmus AFVPLGMTDSLVIV-EEDDSAIIPCRTTDPETQ--VTLHNNGR-LV--P---ASYDSRQG
KIT_Mmus LFL-V---GLPLFG-KEDSDALVRCPLTDPQVS-NYSLIECDGKSLPTDLT-FVPNPKAG
FMS_Mmus SWNLL---AQEVTV-VEGQEAVLPCLITDPALKDSVSLMREGGRQVLRKTV-YFFSPWRG
FLT3_Mmus LYV-L---RRPYFRKMENQDALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKV
: : . : * * .
PDGFRb_Hsap FS----G-IFEDRSYICKTTIGDREVDSDAYYVYRLQVS-SI-NVSVNAVQTVVRQGENI
PDGFRa_Hsap FN----G-TFTVGPYICEATVKGKKFQTIPFNVYALKATSEL-DLEMEALKTVYKSGETI
KIT_Hsap IMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEF
FMS_Hsap FTIHRAK-FIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAA
FLT3_Hsap LH----E-LFGTDIRCCARNELGRECT-RLFTIDLN----QTPQTTL--PQLFLKVGEPL
PDGFRb_Mmus FT----G-TFEDKTYICKTTIGDREVDSDTYYVYSLQVS-SI-NVSVNAVQTVVRQGESI
PDGFRa_Mmus FN----G-TFSVGPYICEATVKGRTFKTSEFNVYALKATSEL-NLEMDARQTVYKAGETI
KIT_Mmus ITIKNVKRAYHRLCVRCAAQRDGTWLHSDKFTLKVRAAIKAIPVVSVPETSHLLKKGDTF
FMS_Mmus FIIRKAK-VLDSNTYVCKTMVNGRESTSTGIWLKVNRVHPEPPQIKLEPSKLVRIRGEAA
FLT3_Mmus LH----E-LFGTDIRCCARNALGRECT-KLFTIDLN----QAPQSTL--PQLFLKVGEPL
: * . : : . . *:
PDGFRb_Hsap TLMCIVIGNE-VVNFEWTYPRKESGRL--VEPVTDFLLDMPYHIRSILHIPSAELEDSGT
PDGFRa_Hsap VVTCAVFNNE-VVDLQWTYPGEVKGKG--ITMLEEIKVP-SIKLVYTLTVPEATVKDSGD
KIT_Hsap TVTCTIKDVSSSVYSTWKRENSQTK-LQ-EKYNSWHHGDFNYERQATLTISSARVNDSGV
FMS_Hsap QIVCSASSVDVNFDVFLQHNN--TK-LA-IPQQSDFH-NNRYQKVLTLNLDQVDFQHAGN
FLT3_Hsap WIRCKAVHVNHGFGLTWELENKALEEGNYFEMS-TYSTNRTMIRILFAFVSSVARNDTGY
PDGFRb_Mmus TIRCIVMGND-VVNFQWTYPRMKSGRL--VEPVTDYLFGVPSRIGSILHIPTAELSDSGT
PDGFRa_Mmus VVTCAVFNNE-VVDLQWTYPGEVRNKG--ITMLEEIKLP-SIKLVYTLTVPKATVKDSGE
KIT_Mmus TVVCTIKDVSTSVNSMWLKMNPQPQHIAQVKHNSWHRGDFNYERQETLTISSARVDDSGV
FMS_Mmus QIVCSATNAEVGFNVILKRGD--TK-LE-IPLNSDFQ-DNYYKKVRALSLNAVDFQDAGI
FLT3_Mmus WIRCKAIHVNHGFGLTWELEDKALEEGSYFEMS-TYSTNRTMIRILLAFVSSVGRNDTGY
: * . . : . ..:*
PDGFRb_Hsap YTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPT-
PDGFRa_Hsap YECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPR-
KIT_Hsap FMCYANNTFGSA--NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEH
FMS_Hsap YSCVASNVQGKH--STSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQG
FLT3_Hsap YTCSSSKHP-----SQSALVTIVEKGFINATNSSEDY-EIDQYEEFCFSVRFKAYPQIR-
PDGFRb_Mmus YTCNVSVSVNDHGDEKAINISVIENGYVRLLETLGDVEIAELHRSRTLRVVFEAYPMPS-
PDGFRa_Mmus YECAARQATKEVKEMKRVTISVHEKGFVEIEPTFGQLEAVNLHEVREFVVEVQAYPTPR-
KIT_Mmus FMCYANNTFGSA--NVTTTLKVVEKGFINISPVKNTTVFVTDGENVDLVVEYEAYPKPEH
FMS_Mmus YSCVASNDVGTR--TATMNFQVVESAYLNLTSEQSLLQEVSVGDSLILTVHADAYPSIQH
FLT3_Mmus YTCSSSKHP-----SQSALVTILEKGFINATSSQEEY-EIDPYEKFCFSVRFKAYPRIR-
: * . : :..::. : * *:*
PDGFRb_Hsap VLWFKDNRTLGDSSAGEIALSTRNVSETRYV-SELTLVRVKVAEAGHYTMRAFHEDAEVQ
PDGFRa_Hsap ISWLKNNLTLIENL-TEITTDVEKIQEIRYR-SKLKLIRAKEEDSGHYTIVAQNEDAVKS
KIT_Hsap QQWIYMNRTFTDKW-EDYP-KSENESNIRYV-SELHLTRLKGTEGGTYTFLVSNSDVNAA
FMS_Hsap FNWTYLGPFSDHQP-EPKLANATTKDTYRHT-FTLSLPRLKPSEAGRYSFLARNPGGWRA
FLT3_Hsap CTWTFSRKSFPCEQKGLD--N-------GYSISKF--C-NHKHQPGEYIFHAENDDAQFT
PDGFRb_Mmus VLWLKDNRTLGDSGAGELVLSTRNMSETRYV-SELILVRVKVSEAGYYTMRAFHEDDEVQ
PDGFRa_Mmus ISWLKDNLTLIENL-TEITTDVQKSQETRYQ-SKLKLIRAKEEDSGHYTIIVQNEDDVKS
KIT_Mmus QQWIYMNRTSANKG-KDYV-KSDNKSNIRYV-NQLRLTRLKGTEGGTYTFLVSNSDASAS
FMS_Mmus YNWTYLGPFFEDQR-KLEFI--TQRAIYRYT-FKLFLNRVKASEAGQYFLMAQNKAGWNN
FLT3_Mmus CTWIFSQASFPCEQRGLE--D-------GYSISKF--C-DHKNKPGEYIFYAENDDAQFT
* . : : : . * * : . :
PDGFRb_Hsap LSFQLQINVPVRVLELSESH-PDSGEQTVRCRGRGMPQPNIIWSACRDL-KRCPRELPP-
PDGFRa_Hsap YTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDI-KKCNNETSW-
KIT_Hsap IAFNVYVNTKPEILTYDR---LVNG--MLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPV
FMS_Hsap LTFELTLRYPPEVSVIWT---FINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVL-
FLT3_Hsap KMFTLNIRRKPQVLAEAS---A----SQASCFSDGYPLPSWTWKKCSDKSPNCTEEITE-
PDGFRb_Mmus LSFKLQVNVPVRVLELSESH-PANGEQTIRCRGRGMPQPNVTWSTCRDL-KRCPRKLSP-
PDGFRa_Mmus YTFELSTLVPASILDLVDDHHGSGGGQTVRCTAEGTPLPEIDWMICKHI-KKCNNDTSW-
KIT_Mmus VTFNVYVNTKPEILTYDR---LING--MLQCVAEGFPEPTIDWYFCTGAEQRCTTPVSPV
FMS_Mmus LTFELTLRYPPEVSVTWM---PVNGSDVLFCDVSGYPQPSVTWMECRGHTDRCDEAQAL-
FLT3_Mmus KMFTLNIRKKPQVLANAS---A----SQASCSSDGYPLPSWTWKKCSDKSPNCTEEIPE-
* : : * * * * * * .*
PDGFRb_Hsap TLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIV
PDGFRa_Hsap TILANNVSN------IITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKL
KIT_Hsap DVQT----L-------NSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNF
FMS_Hsap QVWDDPYPE-------VLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIP
FLT3_Hsap GVWNRK-----------ANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILL
PDGFRb_Mmus TPLGNSSKEESQLETNVTFWEEDQEYEVVSTLRLRHVDQPLSVRCMLQNSMGGDSQEVTV
PDGFRa_Mmus TVLASNVSN------IITELPRRGRSTVEGRVSFAKVEETIAVRCLAKNNLSVVARELKL
KIT_Mmus DVQV----Q-------NVSVSPFGKLVVQSSIDSSVFRHNGTVECKASNDVGKSSAFFNF
FMS_Mmus QVWNDTHPE-------VLSQKPFDKVIIQSQLPIGTLKHNMTYFCKTHNSVGNSSQYFRA
FLT3_Mmus GVWNKK-----------ANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFL
. . : . * * :. .
PDGFRb_Hsap VP----------HSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVS
PDGFRa_Hsap VA----------PTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESIS
KIT_Hsap AFKGNNKEQIHPHTL-FTPLLIGFVI-VAGMMCIIVMILTYKYLQKPMYEVQWKVVEEI-
FMS_Hsap ISAGAH-THPPDEFL-FTPVVVACMS-IMALLLLLLLLLLYKYKQKPKYQVRWKIIESY-
FLT3_Hsap NSPGPF-PFIQDNIS-FY----ATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTG
PDGFRb_Mmus VP----------HSLPFKVVVISAILALVVLTVISLIILIMLWQKKPRYEIRWKVIESVS
PDGFRa_Mmus VA----------PTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESIS
KIT_Mmus AFKGNNKEQIQAHTL-FTPLLIGFVV-AAGAMGIIVMVLTYKYLQKPMYEVQWKVVEEI-
FMS_Mmus VSLGQS-KQLPDESL-FTPVVVACMS-VMSLLVLLLLLLLYKYKQKPKYQVRWKIIERY-
FLT3_Mmus NSPGPF-PFIQDNIS-FY----ATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTG
. : : ::: : :: *: : ::::
PDGFRb_Hsap SDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAV
PDGFRa_Hsap PDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAV
KIT_Hsap -NGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAV
FMS_Hsap -EGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAV
FLT3_Hsap SSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAV
PDGFRb_Mmus SDGHEYIYVDPVQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAV
PDGFRa_Mmus PDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAV
KIT_Mmus -NGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAV
FMS_Mmus -EGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAV
FLT3_Mmus PLDNEYFYVDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAV
.:.* ::* : *: **:**: * :*: **:****:*::.**.*: : : ***
PDGFRb_Hsap KMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYL
PDGFRa_Hsap KMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYL
KIT_Hsap KMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFL
FMS_Hsap KMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFL
FLT3_Hsap KMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYL
PDGFRb_Mmus KMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYL
PDGFRa_Mmus KMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYL
KIT_Mmus KMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFL
FMS_Mmus KMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFL
FLT3_Mmus KMLKEKADSCEKEALMSELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYL
**** .* *::*******::: ** * *:******** .** :* *** ****:::*
PDGFRb_Hsap HRNKHTFLQHHSD-KRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYV
PDGFRa_Hsap HKNRDSFLSHHPE-KP--KKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYV
KIT_Hsap RRKRDSFICSKQ---EDHAEAALYKNLLHSKESS------CSDSTNEYMDMKPGVS-YVV
FMS_Hsap RRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVST----
FLT3_Hsap RSKREKFHRTWTE-IFKEHNFSFYPTFQSHPNSS-------MPGS-REVQIHP-------
PDGFRb_Mmus HRNKHTFLQRHSN-KHCPPSAELYSNALPVGFSLPSHLNLTGESDGGYMDMSKDESIDYV
PDGFRa_Mmus HKNRDSFMSQHPE-KP--KKDLDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYV
KIT_Mmus RRKRDSFIFSKQ---EEQAEAALYKNLLHSTEPS-------CDSSNEYMDMKPGVS-YVV
FMS_Mmus RRKAEAMLGPSLSPGQDSEGDSSYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVST----
FLT3_Mmus RSKREKFHRTWTE-IFKEHNFSFYPTFQAHSNSS-------MPGS-REVQLHP-------
: : . : . :::
PDGFRb_Hsap PMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATL---I-NESPVLSYMDLVGFSY
PDGFRa_Hsap PMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLL---SDDNSEGLTLLDLLSFTY
KIT_Hsap PT---------------KADKRRSVRIGSYIERDVTPAI---MEDDELALDLEDLLSFSY
FMS_Hsap ------------------------SS----NDSFSEQDL---DKEDGRPLELRDLLHFSS
FLT3_Hsap -DSDQISGLH-----------GNSFHSEDEIEYENQKRLE--EEEDLNVLTFEDLLCFAY
PDGFRb_Mmus PMLDMKGDIKYADIESPSYMAPYDNYVPSAPERTYRATL---I-NDSPVLSYTDLVGFSY
PDGFRa_Mmus PMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLL---SDDDSEGLTLLDLLSFTY
KIT_Mmus PT---------------KTDKRRSARIDSYIERDVTPAI---MEDDELALDLDDLLSFSY
FMS_Mmus ------------------------SS----SDSFFKQDL---DKEASRPLELWDLLHFSS
FLT3_Mmus -PLDQLSGFN-----------GNLIHSEDEIEYENQKRLAEEEEEDLNVLTFEDLLCFAY
: : : * **: *:
PDGFRb_Hsap QVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLK
PDGFRa_Hsap QVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVK
KIT_Hsap QVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVK
FMS_Hsap QVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVK
FLT3_Hsap QVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVK
PDGFRb_Mmus QVANGMDFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLK
PDGFRa_Mmus QVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVK
KIT_Mmus QVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYVVKGNARLPVK
FMS_Mmus QVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVK
FLT3_Mmus QVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVK
***.** ** *.*:***:****:*: *::.** ******** **.*: :*.: **:*
PDGFRb_Hsap WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAH
PDGFRa_Hsap WMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDH
KIT_Hsap WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH
FMS_Hsap WMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAF
FLT3_Hsap WMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFY
PDGFRb_Mmus WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAH
PDGFRa_Mmus WMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDH
KIT_Mmus WMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEH
FMS_Mmus WMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVF
FLT3_Mmus WMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFY
******:*. :** *****:**:***:*:** .*** : :: **: :: *::* .* .
PDGFRb_Hsap ASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGE-GYKKKYQQVDEEFLRSDHPAILR
PDGFRa_Hsap ATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPG-QYKKSYEKIHLDFLKSDHPAVAR
KIT_Hsap APAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISE-STNHIYSNLANCSPNRQKPVV-D
FMS_Hsap APKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTNLPSSS----------
FLT3_Hsap ATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLAD-AEEAMYQNVDGRV--SECPHTYQ
PDGFRb_Mmus ASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLLGE-GYKKKYQQVDEEFLRSDHPAILR
PDGFRa_Mmus ATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPG-QYKKSYEKIHLDFLKSDHPAVAR
KIT_Mmus APAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQISD-STKHIYSNLANCNPNPENPVVVD
FMS_Mmus APKNIYSIMQSCWDLEPTRRPTFQQICFLLQEQARLERRDQDYANLPSSGGSSG------
FLT3_Mmus ATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAE-AEEAMYQNMGGNV--PEHPSIYQ
*. :* :* ** . **.* :: :: . * ::
PDGFRb_Hsap SQARLPGFHGLRSPLDTSSVLYTAVQPN-----------------EGDNDYIIPLPDPKP
PDGFRa_Hsap MRVDS------------DNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDP
KIT_Hsap HS----------------------------------------------------------
FMS_Hsap ------------------------------------------------------------
FLT3_Hsap NRRP--------------------------------------------------------
PDGFRb_Mmus SQARFPGIHSLRSPLDTSSVLYTAVQPN-----------------ESDNDYIIPLPDPKP
PDGFRa_Mmus MRVDS------------DNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDP
KIT_Mmus HS----------------------------------------------------------
FMS_Mmus ------------------------------------------------------------
FLT3_Mmus NRRP--------------------------------------------------------
PDGFRb_Hsap EVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLP
PDGFRa_Hsap VPEEEDL--GKRNRHSSQTSEESAIETGSSSSTFIKREDE-----------TIEDIDMMD
KIT_Hsap ------------------VRINSVGSTASS------------------------------
FMS_Hsap ---------------------RSGGSGSSSS-E--LEEES-----------SSEHLTCCE
FLT3_Hsap -------------------FSREMD-----------------------------------
PDGFRb_Mmus DVADEGLPEGSPSLASSTLNEVNTSSTISCDSPLELQEEPQ-------QAEPEAQLEQPQ
PDGFRa_Mmus VPEEEDL--GKRNRHSSQTSEESAIETGSSSSTFIKREDE-----------TIEDIDMMD
KIT_Mmus ------------------VRVNSVGSSASS------------------------------
FMS_Mmus ------------------SDSGGGSSGGSSS-E--PEEES-----------SSEHLACCE
FLT3_Mmus -------------------LSREAG-----------------------------------
PDGFRb_Hsap DSGCPAPRAE--AEDSFL
PDGFRa_Hsap DIGIDSSD-L--VEDSFL
KIT_Hsap ----SQPLLVH----DDV
FMS_Hsap QGDIAQPLLQP-NNYQFC
FLT3_Hsap -LGLLSPQA----QVEDS
PDGFRb_Mmus DSGCPGPLAE--AEDSFL
PDGFRa_Mmus DIGIDSSD-L--VEDSFL
KIT_Mmus ----TQPLLVH----EDA
FMS_Mmus PGDIAQPLLQP-NNYQFC
FLT3_Mmus -SEPPSPQAQVKIHGERS
. .