Protein (view, download) , Domain (view, download)
PDGFRb_Hsap     MRLPGAMPALALKGELLLLSLLLL--------------L------------EPQI-----
PDGFRa_Hsap     MGTS--HPA------FLVLGCLLT-------GLS---LI------------LCQL-----
KIT_Hsap        MRGA--RGAWD---FLCVLLLLLRVQ----TGSSQPSVS------------PGEP-----
FMS_Hsap        MGPG--V-------L--LLLLVATAW----HGQG--------------------------
FLT3_Hsap       MPAL--ARDGG---QLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPM
PDGFRb_Mmus     MGLPGVIPALVLRGQL-LLSVLWL--------------L------------GPQT-----
PDGFRa_Mmus     MGTS--HQV------FLVLSCLLT-------GPG---LI------------SCQL-----
KIT_Mmus        MRGA--RGAWD---LLCVLLVLLRGQ----TATSQPSAS------------PGEP-----
FMS_Mmus        MELG--P-------P--LVLLLATVW----HGQG--------------------------
FLT3_Mmus       MRAL--AQRSD--RRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRM
                *                ::  .

PDGFRb_Hsap     ---------------SQGLVVTPPGPELVLNVSSTFVLTCS--GSAPVVWERMSQE-PPQ
PDGFRa_Hsap     ---------------S-LPSILPNENEKVVQLNSSFSLRCF--GESEVSWQYPMSE-EES
KIT_Hsap        ---------------S-PPSIHPGKSDLIVRVGDEIRLLCT--DPGFVKWTFEIL----D
FMS_Hsap        -----------------IPVIEPSVPELVVKPGATVTLRCV--GNGSVEWDGPPSP-HWT
FLT3_Hsap       VSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQ
PDGFRb_Mmus     ---------------SRGLVITPPGPEFVLNISSTFVLTCS--GSAPVMWEQMSQV-PWQ
PDGFRa_Mmus     ---------------L-LPSILPNENEKIVQLNSSFSLRCV--GESEVSWQHPMSE-EDD
KIT_Mmus        ---------------S-PPSIHPAQSELIVEAGDTLSLTCI--DPDFVRWTFKTYF---N
FMS_Mmus        -----------------APVIEPSGPELVVEPGETVTLRCV--SNGSVEWDGPISP-YWT
FLT3_Mmus       VRGSPEDLQCAPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQ
                                      .   :     .  . :     .     *

PDGFRb_Hsap     ---E--MAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLET-DERKRLYIFVPDPTV
PDGFRa_Hsap     SDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDV
KIT_Hsap        E-----TNENK----QNEWITEKAEATNTGKYTCTNKH-------GLSNSIYVFVRDPAK
FMS_Hsap        L-----YSDGS----SSILSTNNATFQNTGTYRCTEPGD---P-LGGSAAIHLYVKDPAR
FLT3_Hsap       PHFDLQ----NRGV-VSM-VILKMTETQAGEYLLFIQSEA----TNYTILFTVSIRNT-L
PDGFRb_Mmus     ---E--AAMNQDGTFSSVLTLTNVTGGDTGEYFCVYNNSLGPEL-SERKRIYIFVPDPTM
PDGFRa_Mmus     PNVEIRSEENNSGLFVTVLEVVNASAAHTGWYTCYYNHTQTDESEIEGRHIYIYVPDPDM
KIT_Mmus        E-----MVENK----KNEWIQEKAEATRTGTYTCSNSN-------GLTSSIYVFVRDPAK
FMS_Mmus        L-----DPESP----GSTLTTRNATFKNTGTYRCTELED---P-MAGSTTIHLYVKDPAH
FLT3_Mmus       PHFDLQ----NRGI-VSM-AILNVTETQAGEYLLHIQSEA----ANYTVLFTVNVRDT-Q
                                .     .     :* *                  : : : :.

PDGFRb_Hsap     GFLPNDAEELFIFL-TEITEITIPCRVTDPQLV--VTLHEKKG-DVALP---VPYDHQRG
PDGFRa_Hsap     AFVPLGMTDYLVIV-EDDDSAIIPCRTTDPETP--VTLHNSEG-VV--P---ASYDSRQG
KIT_Hsap        LFL-V---DRSLYG-KEDNDTLVRCPLTDPEVT-NYSLKGCQGKPLPKDLR-FIPDPKAG
FMS_Hsap        PWNVL---AQEVVV-FEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTN-YSFSPWHG
FLT3_Hsap       LYT-L---RRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKV
PDGFRb_Mmus     GFLPMDSEDLFIFV-TDVTETTIPCRVTDPQLE--VTLHEKKV-DIPLH---VPYDHQRG
PDGFRa_Mmus     AFVPLGMTDSLVIV-EEDDSAIIPCRTTDPETQ--VTLHNNGR-LV--P---ASYDSRQG
KIT_Mmus        LFL-V---GLPLFG-KEDSDALVRCPLTDPQVS-NYSLIECDGKSLPTDLT-FVPNPKAG
FMS_Mmus        SWNLL---AQEVTV-VEGQEAVLPCLITDPALKDSVSLMREGGRQVLRKTV-YFFSPWRG
FLT3_Mmus       LYV-L---RRPYFRKMENQDALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKV
                 :              :  .  :      *       *                 .

PDGFRb_Hsap     FS----G-IFEDRSYICKTTIGDREVDSDAYYVYRLQVS-SI-NVSVNAVQTVVRQGENI
PDGFRa_Hsap     FN----G-TFTVGPYICEATVKGKKFQTIPFNVYALKATSEL-DLEMEALKTVYKSGETI
KIT_Hsap        IMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEF
FMS_Hsap        FTIHRAK-FIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAA
FLT3_Hsap       LH----E-LFGTDIRCCARNELGRECT-RLFTIDLN----QTPQTTL--PQLFLKVGEPL
PDGFRb_Mmus     FT----G-TFEDKTYICKTTIGDREVDSDTYYVYSLQVS-SI-NVSVNAVQTVVRQGESI
PDGFRa_Mmus     FN----G-TFSVGPYICEATVKGRTFKTSEFNVYALKATSEL-NLEMDARQTVYKAGETI
KIT_Mmus        ITIKNVKRAYHRLCVRCAAQRDGTWLHSDKFTLKVRAAIKAIPVVSVPETSHLLKKGDTF
FMS_Mmus        FIIRKAK-VLDSNTYVCKTMVNGRESTSTGIWLKVNRVHPEPPQIKLEPSKLVRIRGEAA
FLT3_Mmus       LH----E-LFGTDIRCCARNALGRECT-KLFTIDLN----QAPQSTL--PQLFLKVGEPL
                :               *     .         :             :   . .   *:

PDGFRb_Hsap     TLMCIVIGNE-VVNFEWTYPRKESGRL--VEPVTDFLLDMPYHIRSILHIPSAELEDSGT
PDGFRa_Hsap     VVTCAVFNNE-VVDLQWTYPGEVKGKG--ITMLEEIKVP-SIKLVYTLTVPEATVKDSGD
KIT_Hsap        TVTCTIKDVSSSVYSTWKRENSQTK-LQ-EKYNSWHHGDFNYERQATLTISSARVNDSGV
FMS_Hsap        QIVCSASSVDVNFDVFLQHNN--TK-LA-IPQQSDFH-NNRYQKVLTLNLDQVDFQHAGN
FLT3_Hsap       WIRCKAVHVNHGFGLTWELENKALEEGNYFEMS-TYSTNRTMIRILFAFVSSVARNDTGY
PDGFRb_Mmus     TIRCIVMGND-VVNFQWTYPRMKSGRL--VEPVTDYLFGVPSRIGSILHIPTAELSDSGT
PDGFRa_Mmus     VVTCAVFNNE-VVDLQWTYPGEVRNKG--ITMLEEIKLP-SIKLVYTLTVPKATVKDSGE
KIT_Mmus        TVVCTIKDVSTSVNSMWLKMNPQPQHIAQVKHNSWHRGDFNYERQETLTISSARVDDSGV
FMS_Mmus        QIVCSATNAEVGFNVILKRGD--TK-LE-IPLNSDFQ-DNYYKKVRALSLNAVDFQDAGI
FLT3_Mmus       WIRCKAIHVNHGFGLTWELEDKALEEGSYFEMS-TYSTNRTMIRILLAFVSSVGRNDTGY
                 : *     .  .                                    :  .  ..:*

PDGFRb_Hsap     YTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPT-
PDGFRa_Hsap     YECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPR-
KIT_Hsap        FMCYANNTFGSA--NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEH
FMS_Hsap        YSCVASNVQGKH--STSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQG
FLT3_Hsap       YTCSSSKHP-----SQSALVTIVEKGFINATNSSEDY-EIDQYEEFCFSVRFKAYPQIR-
PDGFRb_Mmus     YTCNVSVSVNDHGDEKAINISVIENGYVRLLETLGDVEIAELHRSRTLRVVFEAYPMPS-
PDGFRa_Mmus     YECAARQATKEVKEMKRVTISVHEKGFVEIEPTFGQLEAVNLHEVREFVVEVQAYPTPR-
KIT_Mmus        FMCYANNTFGSA--NVTTTLKVVEKGFINISPVKNTTVFVTDGENVDLVVEYEAYPKPEH
FMS_Mmus        YSCVASNDVGTR--TATMNFQVVESAYLNLTSEQSLLQEVSVGDSLILTVHADAYPSIQH
FLT3_Mmus       YTCSSSKHP-----SQSALVTILEKGFINATSSQEEY-EIDPYEKFCFSVRFKAYPRIR-
                : *                . : :..::.                  : *   *:*

PDGFRb_Hsap     VLWFKDNRTLGDSSAGEIALSTRNVSETRYV-SELTLVRVKVAEAGHYTMRAFHEDAEVQ
PDGFRa_Hsap     ISWLKNNLTLIENL-TEITTDVEKIQEIRYR-SKLKLIRAKEEDSGHYTIVAQNEDAVKS
KIT_Hsap        QQWIYMNRTFTDKW-EDYP-KSENESNIRYV-SELHLTRLKGTEGGTYTFLVSNSDVNAA
FMS_Hsap        FNWTYLGPFSDHQP-EPKLANATTKDTYRHT-FTLSLPRLKPSEAGRYSFLARNPGGWRA
FLT3_Hsap       CTWTFSRKSFPCEQKGLD--N-------GYSISKF--C-NHKHQPGEYIFHAENDDAQFT
PDGFRb_Mmus     VLWLKDNRTLGDSGAGELVLSTRNMSETRYV-SELILVRVKVSEAGYYTMRAFHEDDEVQ
PDGFRa_Mmus     ISWLKDNLTLIENL-TEITTDVQKSQETRYQ-SKLKLIRAKEEDSGHYTIIVQNEDDVKS
KIT_Mmus        QQWIYMNRTSANKG-KDYV-KSDNKSNIRYV-NQLRLTRLKGTEGGTYTFLVSNSDASAS
FMS_Mmus        YNWTYLGPFFEDQR-KLEFI--TQRAIYRYT-FKLFLNRVKASEAGQYFLMAQNKAGWNN
FLT3_Mmus       CTWIFSQASFPCEQRGLE--D-------GYSISKF--C-DHKNKPGEYIFYAENDDAQFT
                  *         .                :    :     :  . * * : . :

PDGFRb_Hsap     LSFQLQINVPVRVLELSESH-PDSGEQTVRCRGRGMPQPNIIWSACRDL-KRCPRELPP-
PDGFRa_Hsap     YTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDI-KKCNNETSW-
KIT_Hsap        IAFNVYVNTKPEILTYDR---LVNG--MLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPV
FMS_Hsap        LTFELTLRYPPEVSVIWT---FINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVL-
FLT3_Hsap       KMFTLNIRRKPQVLAEAS---A----SQASCFSDGYPLPSWTWKKCSDKSPNCTEEITE-
PDGFRb_Mmus     LSFKLQVNVPVRVLELSESH-PANGEQTIRCRGRGMPQPNVTWSTCRDL-KRCPRKLSP-
PDGFRa_Mmus     YTFELSTLVPASILDLVDDHHGSGGGQTVRCTAEGTPLPEIDWMICKHI-KKCNNDTSW-
KIT_Mmus        VTFNVYVNTKPEILTYDR---LING--MLQCVAEGFPEPTIDWYFCTGAEQRCTTPVSPV
FMS_Mmus        LTFELTLRYPPEVSVTWM---PVNGSDVLFCDVSGYPQPSVTWMECRGHTDRCDEAQAL-
FLT3_Mmus       KMFTLNIRKKPQVLANAS---A----SQASCSSDGYPLPSWTWKKCSDKSPNCTEEIPE-
                  * :       :                 *   * * *   *  *     .*

PDGFRb_Hsap     TLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIV
PDGFRa_Hsap     TILANNVSN------IITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKL
KIT_Hsap        DVQT----L-------NSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNF
FMS_Hsap        QVWDDPYPE-------VLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIP
FLT3_Hsap       GVWNRK-----------ANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILL
PDGFRb_Mmus     TPLGNSSKEESQLETNVTFWEEDQEYEVVSTLRLRHVDQPLSVRCMLQNSMGGDSQEVTV
PDGFRa_Mmus     TVLASNVSN------IITELPRRGRSTVEGRVSFAKVEETIAVRCLAKNNLSVVARELKL
KIT_Mmus        DVQV----Q-------NVSVSPFGKLVVQSSIDSSVFRHNGTVECKASNDVGKSSAFFNF
FMS_Mmus        QVWNDTHPE-------VLSQKPFDKVIIQSQLPIGTLKHNMTYFCKTHNSVGNSSQYFRA
FLT3_Mmus       GVWNKK-----------ANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFL
                                        .    . :      .     *   * :.     .

PDGFRb_Hsap     VP----------HSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVS
PDGFRa_Hsap     VA----------PTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESIS
KIT_Hsap        AFKGNNKEQIHPHTL-FTPLLIGFVI-VAGMMCIIVMILTYKYLQKPMYEVQWKVVEEI-
FMS_Hsap        ISAGAH-THPPDEFL-FTPVVVACMS-IMALLLLLLLLLLYKYKQKPKYQVRWKIIESY-
FLT3_Hsap       NSPGPF-PFIQDNIS-FY----ATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTG
PDGFRb_Mmus     VP----------HSLPFKVVVISAILALVVLTVISLIILIMLWQKKPRYEIRWKVIESVS
PDGFRa_Mmus     VA----------PTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESIS
KIT_Mmus        AFKGNNKEQIQAHTL-FTPLLIGFVV-AAGAMGIIVMVLTYKYLQKPMYEVQWKVVEEI-
FMS_Mmus        VSLGQS-KQLPDESL-FTPVVVACMS-VMSLLVLLLLLLLYKYKQKPKYQVRWKIIERY-
FLT3_Mmus       NSPGPF-PFIQDNIS-FY----ATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTG
                                      . :        :  :::   : ::  *: : ::::

PDGFRb_Hsap     SDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAV
PDGFRa_Hsap     PDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAV
KIT_Hsap        -NGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAV
FMS_Hsap        -EGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAV
FLT3_Hsap       SSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAV
PDGFRb_Mmus     SDGHEYIYVDPVQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAV
PDGFRa_Mmus     PDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAV
KIT_Mmus        -NGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAV
FMS_Mmus        -EGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAV
FLT3_Mmus       PLDNEYFYVDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAV
                  .:.* ::*  :  *:  **:**: * :*: **:****:*::.**.*: :    : ***

PDGFRb_Hsap     KMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYL
PDGFRa_Hsap     KMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYL
KIT_Hsap        KMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFL
FMS_Hsap        KMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFL
FLT3_Hsap       KMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYL
PDGFRb_Mmus     KMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYL
PDGFRa_Mmus     KMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYL
KIT_Mmus        KMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFL
FMS_Mmus        KMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFL
FLT3_Mmus       KMLKEKADSCEKEALMSELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYL
                **** .*   *::*******::: ** * *:******** .**  :* *** ****:::*

PDGFRb_Hsap     HRNKHTFLQHHSD-KRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYV
PDGFRa_Hsap     HKNRDSFLSHHPE-KP--KKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYV
KIT_Hsap        RRKRDSFICSKQ---EDHAEAALYKNLLHSKESS------CSDSTNEYMDMKPGVS-YVV
FMS_Hsap        RRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVST----
FLT3_Hsap       RSKREKFHRTWTE-IFKEHNFSFYPTFQSHPNSS-------MPGS-REVQIHP-------
PDGFRb_Mmus     HRNKHTFLQRHSN-KHCPPSAELYSNALPVGFSLPSHLNLTGESDGGYMDMSKDESIDYV
PDGFRa_Mmus     HKNRDSFMSQHPE-KP--KKDLDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYV
KIT_Mmus        RRKRDSFIFSKQ---EEQAEAALYKNLLHSTEPS-------CDSSNEYMDMKPGVS-YVV
FMS_Mmus        RRKAEAMLGPSLSPGQDSEGDSSYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVST----
FLT3_Mmus       RSKREKFHRTWTE-IFKEHNFSFYPTFQAHSNSS-------MPGS-REVQLHP-------
                : : . :                                    .    :::

PDGFRb_Hsap     PMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATL---I-NESPVLSYMDLVGFSY
PDGFRa_Hsap     PMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLL---SDDNSEGLTLLDLLSFTY
KIT_Hsap        PT---------------KADKRRSVRIGSYIERDVTPAI---MEDDELALDLEDLLSFSY
FMS_Hsap        ------------------------SS----NDSFSEQDL---DKEDGRPLELRDLLHFSS
FLT3_Hsap       -DSDQISGLH-----------GNSFHSEDEIEYENQKRLE--EEEDLNVLTFEDLLCFAY
PDGFRb_Mmus     PMLDMKGDIKYADIESPSYMAPYDNYVPSAPERTYRATL---I-NDSPVLSYTDLVGFSY
PDGFRa_Mmus     PMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLL---SDDDSEGLTLLDLLSFTY
KIT_Mmus        PT---------------KTDKRRSARIDSYIERDVTPAI---MEDDELALDLDDLLSFSY
FMS_Mmus        ------------------------SS----SDSFFKQDL---DKEASRPLELWDLLHFSS
FLT3_Mmus       -PLDQLSGFN-----------GNLIHSEDEIEYENQKRLAEEEEEDLNVLTFEDLLCFAY
                                               :      :     :    *   **: *:

PDGFRb_Hsap     QVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLK
PDGFRa_Hsap     QVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVK
KIT_Hsap        QVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVK
FMS_Hsap        QVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVK
FLT3_Hsap       QVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVK
PDGFRb_Mmus     QVANGMDFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLK
PDGFRa_Mmus     QVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVK
KIT_Mmus        QVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYVVKGNARLPVK
FMS_Mmus        QVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVK
FLT3_Mmus       QVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVK
                ***.** **  *.*:***:****:*:  *::.** ********  **.*: :*.: **:*

PDGFRb_Hsap     WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAH
PDGFRa_Hsap     WMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDH
KIT_Hsap        WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH
FMS_Hsap        WMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAF
FLT3_Hsap       WMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFY
PDGFRb_Mmus     WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAH
PDGFRa_Mmus     WMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDH
KIT_Mmus        WMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEH
FMS_Mmus        WMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVF
FLT3_Mmus       WMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFY
                ******:*. :**  *****:**:***:*:** .*** : ::  **: :: *::* .* .

PDGFRb_Hsap     ASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGE-GYKKKYQQVDEEFLRSDHPAILR
PDGFRa_Hsap     ATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPG-QYKKSYEKIHLDFLKSDHPAVAR
KIT_Hsap        APAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISE-STNHIYSNLANCSPNRQKPVV-D
FMS_Hsap        APKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTNLPSSS----------
FLT3_Hsap       ATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLAD-AEEAMYQNVDGRV--SECPHTYQ
PDGFRb_Mmus     ASDEIYEIMQKCWEEKFETRPPFSQLVLLLERLLGE-GYKKKYQQVDEEFLRSDHPAILR
PDGFRa_Mmus     ATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPG-QYKKSYEKIHLDFLKSDHPAVAR
KIT_Mmus        APAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQISD-STKHIYSNLANCNPNPENPVVVD
FMS_Mmus        APKNIYSIMQSCWDLEPTRRPTFQQICFLLQEQARLERRDQDYANLPSSGGSSG------
FLT3_Mmus       ATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAE-AEEAMYQNMGGNV--PEHPSIYQ
                *.  :* :*  **  .   **.* ::  ::         .  * ::

PDGFRb_Hsap     SQARLPGFHGLRSPLDTSSVLYTAVQPN-----------------EGDNDYIIPLPDPKP
PDGFRa_Hsap     MRVDS------------DNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDP
KIT_Hsap        HS----------------------------------------------------------
FMS_Hsap        ------------------------------------------------------------
FLT3_Hsap       NRRP--------------------------------------------------------
PDGFRb_Mmus     SQARFPGIHSLRSPLDTSSVLYTAVQPN-----------------ESDNDYIIPLPDPKP
PDGFRa_Mmus     MRVDS------------DNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDP
KIT_Mmus        HS----------------------------------------------------------
FMS_Mmus        ------------------------------------------------------------
FLT3_Mmus       NRRP--------------------------------------------------------


PDGFRb_Hsap     EVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLP
PDGFRa_Hsap     VPEEEDL--GKRNRHSSQTSEESAIETGSSSSTFIKREDE-----------TIEDIDMMD
KIT_Hsap        ------------------VRINSVGSTASS------------------------------
FMS_Hsap        ---------------------RSGGSGSSSS-E--LEEES-----------SSEHLTCCE
FLT3_Hsap       -------------------FSREMD-----------------------------------
PDGFRb_Mmus     DVADEGLPEGSPSLASSTLNEVNTSSTISCDSPLELQEEPQ-------QAEPEAQLEQPQ
PDGFRa_Mmus     VPEEEDL--GKRNRHSSQTSEESAIETGSSSSTFIKREDE-----------TIEDIDMMD
KIT_Mmus        ------------------VRVNSVGSSASS------------------------------
FMS_Mmus        ------------------SDSGGGSSGGSSS-E--PEEES-----------SSEHLACCE
FLT3_Mmus       -------------------LSREAG-----------------------------------


PDGFRb_Hsap     DSGCPAPRAE--AEDSFL
PDGFRa_Hsap     DIGIDSSD-L--VEDSFL
KIT_Hsap        ----SQPLLVH----DDV
FMS_Hsap        QGDIAQPLLQP-NNYQFC
FLT3_Hsap       -LGLLSPQA----QVEDS
PDGFRb_Mmus     DSGCPGPLAE--AEDSFL
PDGFRa_Mmus     DIGIDSSD-L--VEDSFL
KIT_Mmus        ----TQPLLVH----EDA
FMS_Mmus        PGDIAQPLLQP-NNYQFC
FLT3_Mmus       -SEPPSPQAQVKIHGERS
                      .        .