HSER_Hsap LKIDDDK----------------------------------R---R--------------
CG10738_Dmel TT----------------------------------------------------------
CG9783_Dmel TTANGKS----------------------------------GSS-------ATG------
Gyc32E_Dmel QSIL------------------VV-----------------GEPN---------------
Gyc76C_Dmel LEIEGLLWKIDPNEIKGYSGNEIV-----------------SSPSK--VSLMSA------
CG4224_Dmel Q-----------------------------------------------------------
CG3216_Dmel P-----------------------------------------------------------
KSGC_Mmus SLVK-------------------R------------------------------------
HSER_Mmus LKIDDDR----------------------------------R---R--------------
CYGX_Mmus RSVVD------------------G-----------------G-SPR---SVTQG------
CYGF_Mmus FQIISEV---------------QS-----------------GRSPR--LSFSSG------
CYGD_Mmus RSAS--------------------------------------------------------
ANPb_Mmus GSRLTLS---------------L-------------------RG------SSYG------
ANPa_Mmus GSRLTLS---------------G-------------------RG------SNYG------
odr-1_Cele FGSYALV---------------GT------------------------------------
gcy-9_Cele SKQNGLI---------------AA-----------------K------------------
gcy-8_Cele SRNHAIV---------------GT------------------------------------
gcy-7_Cele ----------------------------------QINSKQKGKGEHSVRSLQSGTSTLSS
gcy-6_Cele ----------------------------------E-------------------------
gcy-5_Cele QM--------------------------------FE------------------------
gcy-4_Cele SKSGDTM---------------TSEFKETYTIQYLE------------------------
gcy-3_Cele ----------------------------------FE------------------------
gcy-27_Cele FGSYALI---------------GT------------------------------------
gcy-25_Cele ------------------------------------------------------------
gcy-23_Cele VKHHAVV---------------GT------------------------------------
gcy-22_Cele ----------------------------------N-------------------------
gcy-21_Cele EG----------------------------------------------------------
gcy-20_Cele ----------------------------------H-------------------------
gcy-2_Cele ----------------------------------YE------------------------
gcy-19_Cele -----------------------------------D------------------------
gcy-18_Cele QKQHAII---------------GV------------------------------------
gcy-17_Cele ----------------------------------L-------------------------
gcy-15_Cele EG----------------------------------------------------------
gcy-14_Cele ----------------------------------Q-------------------------
gcy-13_Cele ----------------------------------YM------------------------
gcy-12_Cele YEVRRVV---------------GG-----------------VN-NE-----STA------
gcy-11_Cele ------------------------------------------------------------
gcy-1_Cele ----------------------------------YE------------------------
daf-11_Cele MEEKQRL---------------QS------------------------------------
C04H5.4_Cele ------------------------------------------------------------
CYGF_Hsap FQITSEV---------------QS-----------------GRSPR--LSFSSG------
ANPb_Hsap GSRLTLS---------------L-------------------RG------SSYG------
ANPa_Hsap GSRLTLS---------------G-------------------RG------SNYG------
CYGD_Hsap ARSMS-------------------------------------------------------
T01A4.1_Cele AQN---------------------------------------------------------
Npr1_Spur ------------------------------------------------------------
Npr2_Spur ------------------------------------------------------------
Gcy3_Spur ------------------------------------------------------------
Npr3_Spur ------------------------------------------------------------
Npr4_Spur ------------------------------------------------------------
Gcy1_Spur ------------------------------------------------------------
Gcy2_Spur ------------------------------------------------------------
Npr5_Spur ------------------------------------------------------------
AqueK220_Aque ------------------------------------------------------------
AqueK221_Aque ------------------------------------------------------------
AqueK222_Aque ------------------------------------------------------------
HSER_Hsap -----------DTIQR------------------LRQCKYDKKR--V-ILKDLKH-----
CG10738_Dmel --------------IF------------------TPIGLYKGQL--Y-AIKKVRK-----
CG9783_Dmel ----SLAR--HNPAHL------------------DMRARYNGDL--V-QLKEVNING---
Gyc32E_Dmel ------------KRSF------------------TNIALFRGNI--V-AMKKIHK-----
Gyc76C_Dmel ----QSYGSRWTNQFV------------------TSTGRLRGAV--V-RIKELKFP----
CG4224_Dmel --------------IF------------------IPVGMFRKSK--V-AIKPVEVD---N
CG3216_Dmel -------------QVY------------------TTIGQFKGER--V-AIKKVNV-----
KSGC_Mmus --------HQDEELFF------------------APVGLYQGNQ--V-ALCYIGDEA---
HSER_Mmus -----------DTIQR------------------VRQCKYDKKK--V-ILKDLKH-----
CYGX_Mmus ----SARSLP-AFLEH------------------TNVALYQGEW--V-WLKKFEAGV---
CYGF_Mmus ----SLT--P-ATYEN------------------SNIAIYEGDW--V-WLKKFPPGDFGD
CYGD_Mmus ----DIRSVPSQPQES------------------TNVGLYEGDW--V-WLKKFPGEH---
ANPb_Mmus ----SLMTAHGKYQIF------------------ANTGHFKGNV--V-AIKHVNK-----
ANPa_Mmus ----SLLTTEGQFQVF------------------AKTAYYKGNL--V-AVKRVNR-----
odr-1_Cele ---------------------------------------QRAE-----YVQFKQI-----
gcy-9_Cele ------------------------------------QAVSNGVK--L-AIKRYQ-Q---V
gcy-8_Cele ---------------------------------------NTHA----IYHKYVQR-----
gcy-7_Cele RTTVSFKTESRNFLFF------------------SLQRESDYEP--V-VAKKHA-Y---R
gcy-6_Cele -----------------------------------------MER--V-AAKKHS-I---R
gcy-5_Cele -----------------------------------------KDL--V-LTTKHH------
gcy-4_Cele -----------------------------------------NDL--V-LTTAHQ------
gcy-3_Cele -----------------------------------------KDM--V-LTMKFQ------
gcy-27_Cele ---------------------------------------QRAE-----FIQFRQI-----
gcy-25_Cele -------------------------------------------K--V-SVKRHV-Q---R
gcy-23_Cele ---------------------------------------NTHA----SFHLYPQR-----
gcy-22_Cele -----------------------------------------NDS--V-VARKHN-F----
gcy-21_Cele ------------------------------------------RT--V-ALKRIYR-----
gcy-20_Cele -----------------------------------------QEV--V-AAKKHD-L----
gcy-2_Cele -----------------------------------------KEM--V-LTAKYQ------
gcy-19_Cele -----------------------------------------KEP--V-LSTAHP------
gcy-18_Cele ---------------------------------------NTHT----TYHRYKQR-----
gcy-17_Cele -----------------------------------------LKVRQI-GVLTPT-S---M
gcy-15_Cele ------------------------------------------RT--V-ALKRIYR-----
gcy-14_Cele -----------------------------------------QDI--L-AAMKHD-L----
gcy-13_Cele -----------------------------------------NEP--V-LARKYQ-L----
gcy-12_Cele ----SLMQ--SDVMQFAKTKTPWWSKAPVQGTGMRGLASYKGTL--V-GLKDLMYG---R
gcy-11_Cele ----------------------------------------ENTL--V-TVRKIN-----K
gcy-1_Cele -----------------------------------------KEM--V-LTAKYQ------
daf-11_Cele -----LAR--T-----------------------KHIATVDQVY--VLADKYVMR-----
C04H5.4_Cele ------------------------------------------------------------
CYGF_Hsap ----SLT--P-ATYEN------------------SNIAIYEGDW--V-WLKKFSLGDFGD
ANPb_Hsap ----SLMTAHGKYQIF------------------ANTGHFKGNV--V-AIKHVNK-----
ANPa_Hsap ----SLLTTEGQFQVF------------------AKTAYYKGNL--V-AVKRVNR-----
CYGD_Hsap ----DIRSGPSQHLDS------------------PNIGVYEGDR--V-WLKKFPGDQ---
T01A4.1_Cele -----------NTQIY------------------TKTAIFKGVV--V-AIKKLNIDPKKY
Npr1_Spur -----------------------------------------GNV--I-AIKRVNR-----
Npr2_Spur -----------------------------------------GRL--V-VIRRIEK-----
Gcy3_Spur -------------------------------------------L--V-AIKKIHK-----
Npr3_Spur ------------------------------------------------------------
Npr4_Spur ----------------------------------------NGQT--V-AVKMIAK-----
Gcy1_Spur ------------------------------------------------------------
Gcy2_Spur ------------------------------------------------------------
Npr5_Spur ------------------------------------------------------------
AqueK220_Aque ------------------------------------------------------------
AqueK221_Aque ------------------------------------------KI--V-KVHKMK-M----
AqueK222_Aque -----------------------------------------GKT--V-AIKKLNYR---S
HSER_Hsap NDG-NFTEKQKIELNKL-LQIDYYNLTKFYGTVKLD----------TMIF-GVIEYCERG
CG10738_Dmel KSV-DITREMKKELKLL-RDARHDNICAFIGACTDP----------PNIC-IISEYCTRG
CG9783_Dmel -SA-ELRTKAMDLLVMA-HGLRHENINPLIGWLSDP----------NRTA-MVFDYCSRG
Gyc32E_Dmel KSV-DITRSIRKELKLM-REVRHENIINFIGASTDH----------GSVI-IFTTYCARG
Gyc76C_Dmel RKR-DISREIMKEMRLL-RELRHDNINSFIGASVEP----------TRIL-LVTDYCAKG
CG4224_Dmel VQG-LLTRSLMLELKRM-KDLQHDHLVKFYGACLDQ----------RRSF-LLTEYCPKG
CG3216_Dmel KKV-DLTPQLLWEIKQA-RDVSHENTVRFVGACIDLP--------RPTVL-ILTEYCSRG
KSGC_Mmus EAW-VKKPTVRREVCLM-CELKHENIVPFFGVCTEP----------PNIC-IVTQYCKKG
HSER_Mmus SDG-NFSEKQKIDLNKL-LQSDYYNLTKFYGTVKLD----------TRIF-GVVEYCERG
CYGX_Mmus -AP-DLRPSSLSFLRKL-REMRHENVTAFLGLFVGP----------GVSA-MVLEHCARG
CYGF_Mmus -IK-SIKSSASDVFEMM-KDLRHENVNPLLGFFYDS----------GMFA-IVSEFCSRR
CYGD_Mmus -HM-AIRPATKTAFSKL-RELRHENVALYLGLFLAGTADSPATPGEGILA-VVSEHCARG
ANPb_Mmus KRI-ELTRQVLFELKHM-RDVQFNHLTRFIGACIDP----------PNIC-IVTEYCPRG
ANPa_Mmus KRI-ELTRKVLFELKHM-RDVQNEHLTRFVGACTDP----------PNIC-ILTEYCPRG
odr-1_Cele RKI-NFPETTLDYLYSL-KQLQHDNLAKFYGIQVNDD--------IMTMT-ILHTLVERG
gcy-9_Cele RNI-TFPKSELRLLKEL-KICENDNLNKFYGISFNQQ---------NEFI-VMWVLCSRG
gcy-8_Cele RPI-VFNRAD------K-TLIxHDNINPFLGMVWNER---------EEML-LVWKFCSRG
gcy-7_Cele PRLD-D--DKCTFMRSL-RNLDQDNLNRFIGLCLDG----------PQML-SVWRFCSRG
gcy-6_Cele MVFDNKTCATMRQVVEM-RLIDHANLNKFIGMSLDA----------PQLY-SVWRFCSRG
gcy-5_Cele -SM-QMNKEEKEKFVKL-RKLEHDNLNKFIGLSIDG----------PQFV-AVWKMCSRG
gcy-4_Cele -VQ-ELSQAEMMKFVKL-RKLDHENLNKFIGLSIDG----------SRFV-SVWKMCSRG
gcy-3_Cele -YM-NLNKADMDKFVKL-RKLDHENLNKFIGLSIDS----------SQFI-SVTKLCSRG
gcy-27_Cele KHI-DITNASLDFLYNL-KQLKHDNLANFYGIQLNDD--------LNTMT-ILHALVERG
gcy-25_Cele RAI-TFSRQEMEMLNQL-KYMSHTNINPFTGICFNQG---------SELI-VMWQFTTRY
gcy-23_Cele RPI-VFNRQDLQLLNQM-KQAVHDNLNPFLGMSFNEK---------EEMV-VLWKFCSRG
gcy-22_Cele -RA-TFTKNDRAMFRKM-RNVDNDNLCKFIGLSLDS----------PTLI-SIWRYCSRG
gcy-21_Cele SDV-EFTRSIRLEIAKL-QESVNSNVIEFVGMVVQSP----------DVF-VVYELAQRG
gcy-20_Cele -LV-LFDANQKSEFRQM-RNFDNDNLNKFIGLCLDG----------PQLL-SLWRFCSRG
gcy-2_Cele -YT-HLTKADKERFVKM-RKLDHENINRFIGLSIDS----------AHFI-AVTKLCSRG
gcy-19_Cele -AS-NLIRTDYDTFVRL-RKLDHENVNKFVGMSIDG----------PEYL-AVWKLCMRG
gcy-18_Cele RPI-KFIKEDMQLLTQM-KQAVHDNLNPFLGAAFNEK---------EEML-VLWKFCSRG
gcy-17_Cele PYL-KPKLSYFSSMHHM-RSLDHDNLNKFIGLCLNS----------QQLL-SIWRYCSRG
gcy-15_Cele SDV-EFTRSNRLEIAKL-QESVNSNVIEFVGMVVQSP----------DVF-VVYELAQRG
gcy-14_Cele -IL-QFDAEQKAEFRQM-RNFDNDNLNKFIGLCLDG----------PQLF-SLWRFCSRG
gcy-13_Cele -RV-PIFKQDRSELRML-RSIEHDNVNRFIGLSIDG----------PVYM-SFWRYCSRG
gcy-12_Cele KPK-DLTREAKKELRAM-RQLAHPNVNNFLGIIVCQ----------YSVT-VVREYCSKG
gcy-11_Cele TQL-KLTREMKQEIDLL-MNETHENLNRFFGLINES----------DLIF-TIHSYGPRK
gcy-1_Cele -YT-HLTKADKERFVKM-RKLDHENINRFIGLSIDS----------AHFI-SVTKLCSRG
daf-11_Cele DKL-RYDKIDINLLYQMKSHLQHDNLNSFVGITIDKA---------SHMY-IIWNQCFRG
C04H5.4_Cele ------------------KQAVHDNINPFIGVSFNEK---------SELL-LLWKFCSRG
CYGF_Hsap -LK-SIKSRASDVFEMM-KDLRHENINPLLGFFYDS----------GMFA-IVTEFCSRG
ANPb_Hsap KRI-ELTRQVLFELKHM-RDVQFNHLTRFIGACIDP----------PNIC-IVTEYCPRG
ANPa_Hsap KRI-ELTRKVLFELKHM-RDVQNEHLTRFVGACTDP----------PNIC-ILTEYCPRG
CYGD_Hsap -HI-AIRPATKTAFSKL-QELRHENVALYLGLFLARGAEGPAALWEGNLA-VVSEHCTRG
T01A4.1_Cele PRL-DLSRAQLMELKKM-KDLQHDHITRFTGACIDF----------PHYC-VVTEYCPKG
Npr1_Spur QRV-ELNRNVLMEIKHV-RDLQHDHVIKFIGACIDA----------PNIS-IMTEYCPKG
Npr2_Spur TKL-DLTREVLKELNYM-RQVEHNNLVRFVGACVDA----------PNIS-IISEYCPKG
Gcy3_Spur RHV-DLTRSVRKELKII-RDLRHPHLNQFIGACVDP----------PNIC-TITEYCPKG
Npr3_Spur ----------------M-RNLEHTNVVRFVGACVDP----------PDQA-ILTEYCPRG
Npr4_Spur NSF-TLDKRIRKEVKQV-RDLQHSNLCKFAGGCIEVP----------NVS-IITEYCPKG
Gcy1_Spur -------RAVRTELKIM-RDMRHDNICPFIGACIDR----------PHIS-ILMHYCAKG
Gcy2_Spur ------------------------------------------------------------
Npr5_Spur -------KAIKRELKEM-RWLVHDNINRFLGLCFPST-------SGDMFY-HVSEFSPKG
AqueK220_Aque ------------KILTI-LDFKHDNICPFVGGILQG----------SLITGLMYEYCTRG
AqueK221_Aque NIS-TLDLNLRKTMLQI-LNFDHENICPFIGCILQG----------PTIVGMMHEYCSHG
AqueK222_Aque REL-QLTKTLRKEVMQI-RSLDHANVCRFIGATLRSS---------ENVI-ILTEYCPKG
HSER_Hsap SLREVLNDTISYPDGTF--MDWEFKISVLYDIA-------KGMSYLHS-SKTEVHGRLKS
CG10738_Dmel SLKDILEN-----EDVK--LDNMFIASMVADII-------RGVIYLHD-SPIRFHGALCT
CG9783_Dmel SLQDVLIM-----DEIK--LDWSFRLSLLTDLV-------RGMRYLHT-SPLRVHGALTS
Gyc32E_Dmel SLEDVLAN-----EDLH--LDHMFISSLVSDIL-------KGMIYLHD-SEIISHGNLRS
Gyc76C_Dmel SLYDIIEN-----EDIK--LDDLFIASLIHDLI-------KGMIYIHN-SQLVYHGNLKS
CG4224_Dmel SLQDILEN-----EQFQ--LDWMFRLSLMHDIV-------RGMQFLHS-SDIRSHGNLKS
CG3216_Dmel SLKDVLEN-----EAIE--LDWNFRMSLIHDIV-------KGMNYLHN-SDVAAHGKLRS
KSGC_Mmus SLQDVMRN-----SDHE--IDWIFKLSFAYDIV-------NGLLFLHG-SPLRSHGNLKP
HSER_Mmus SLREVLNDTISYPDGTF--MDWEFKISVLNDIA-------KGMSYLHS-SKIEVHGRLKS
CYGX_Mmus SLEDLLQN-----ENLR--LDWTFKASLLLDLI-------RGLRYLHH-RRF-PHGRLKS
CYGF_Mmus SLEDILTN-----DDVK--LDWMFKSSLLLDLI-------KGMKYLHH-REF-IHGRLKS
CYGD_Mmus SLHDLLAQ-----REIK--LDWMFKSSLLLDLI-------KGMRYLHH-RGV-AHGRLKS
ANPb_Mmus SLQDILEN-----DSIN--LDWMFRYSLINDLV-------KGMAFLHN-SIISSHGSLKS
ANPa_Mmus SLQDILEN-----ESIT--LDWMFRYSLTNDIV-------KGMLFLHN-GAIGSHGNLKS
odr-1_Cele TLEEFCLD-----RDFG--MDDTFKSAFMRDIL-------KGLQYLHK-SSIGYHGHLQA
gcy-9_Cele SLEDILFN-----DELK--LGRNFQVSFAKDVV-------KGLNFLHT-SPLLHHGMLCL
gcy-8_Cele TLQDIIYN-----ESIQ--LDTKFHGAFIRDIL-------AGLEYLHA-SQIGYHGSLTP
gcy-7_Cele SIADVILK-----ATIQ--MDNFFIYSLIKDMV-------HGLVFLHG-SMVGYHGMLTS
gcy-6_Cele SLADVIRK-----ASMQ--MDGFFIYSLMKDII-------NGLTWIHE-SSHEFHGMLTS
gcy-5_Cele SLQDIIAR-----GNFS--MDGFFMFCIITDIA-------EGMNFLHK-SFLHLHGNLRS
gcy-4_Cele SLQDIISK-----GSFS--MDYFFMFCMIRDIA-------EGLHYIHK-SFLRHHGNLRS
gcy-3_Cele SLLDILYK-----GNFS--MDFFFMYCIIKDVA-------EGMSYLHK-SFLRLHGNLRS
gcy-27_Cele TLEEFCLD-----RDFG--MDETFKSAFMRDIL-------KGLQYLHL-SPVAYHGHLHA
gcy-25_Cele SLEDLIFV-----KEQK--FGRNFQSTFIKHIV-------HGINYIHN-SSIKVHGALYL
gcy-23_Cele TIQDMIYN-----QEVS--LDSKFHGAFIRDIT-------LGLEYLHS-SIIGYHGSLTP
gcy-22_Cele SLQDVIAK-----GSLQ--MDWFFKYSLMRDVA-------DAIYYLHH-SPIGPHGWLSS
gcy-21_Cele SLKDILDN-----DDMP--LDDVFRSQMTKDII-------AGLEYLHS-SPIGCHGRLKS
gcy-20_Cele SLSDVISK-----SSMQ--MDSFFMFSLIRDIS-------NGLYFIHS-SFLKCHGQLTS
gcy-2_Cele SLQDILSR-----GNFS--MDYFFMFCIIRDVA-------KGLEYLHK-TFLRLHGNLRS
gcy-19_Cele SLQDIIGQ-----GNFS--IDPFFMFCVIRDMA-------EGLKYLHN-SFLHVHANLRS
gcy-18_Cele TIQDIIYN-----ANVV--LDEKFHGAFVRDIT-------LGLEYLHA-SPIGYHGSLTP
gcy-17_Cele SLADVISR-----SSMQ--MDSFFMLSLIRDIA-------NGLGFIHT-SMLHFHGYLSS
gcy-15_Cele SLKDILDN-----DDMP--LDDVFRSQMTKDII-------AGLEYLHS-SPVGCHGRLKS
gcy-14_Cele SLSDVISK-----SSMQ--MDSFFMFSLIRDIS-------NGLLFIHN-SFLKCHGHLTS
gcy-13_Cele SIKDVIAK-----SSIN--MDGFFIYCLIKDIASVSRHENPGLQYIHH-SPIKQHGSLTS
gcy-12_Cele SLHDILRN-----ENLK--LDHMYVASFVDDLV-------KGMVYIHD-SELKMHGNLKS
gcy-11_Cele SLMDLLRN-----DDLR--LDRMFKVSFVEDVV-------KGLQFLHEGSKIGYHGNLKS
gcy-1_Cele SLQDILSR-----GNFS--MDYFFMFCIIRDVA-------KGLEYLHK-TFLRLHGNLRS
daf-11_Cele SLHDHIFT-----KERQRGTATRFEGLFLRDIL-------KGLEYIHA-SAIDFHGNLTL
C04H5.4_Cele TLQDVIYC-----EKFA--MDEKFQGAFVRDIT-------MGLEYLHS-SPIGYHGGLAC
CYGF_Hsap SLEDILTN-----QDVK--LDWMFKSSLLLDLI-------KGMKYLHH-REF-VHGRLKS
ANPb_Hsap SLQDILEN-----DSIN--LDWMFRYSLINDLV-------KGMAFLHN-SIISSHGSLKS
ANPa_Hsap SLQDILEN-----ESIT--LDWMFRYSLTNDIV-------KGMLFLHN-GAICSHGNLKS
CYGD_Hsap SLQDLLAQ-----REIK--LDWMFKSSLLLDLI-------KGIRYLHH-RGV-AHGRLKS
T01A4.1_Cele SLEDILEN-----EKIE--LDKLMKYSLLHDLV-------KGLFFLHN-SEIRSHGRLKS
Npr1_Spur SLQDILEN-----DSIE--LDELFKYSLMYDIV-------KGMLYLHN-SVIQTHGNLKS
Npr2_Spur SLQDIVEN-----DALK--LDNMFKNSLITDVM-------RGLHYLHS-SVIMLHSRLSS
Gcy3_Spur SLQDILEN-----DEVK--LDSMFIASLIGDIL-------KGLSCLHA-SETHSHGNLKS
Npr3_Spur SLQDILEN-----DQLK--LDLMFRQSLLMDAV-------RGLNYIHD-SVIGVHGRLTS
Npr4_Spur ALSDVLLN-----EDVP--LNWSFRFSFCMDVA-------RGMHYMHN-NKL-YHGKLTS
Gcy1_Spur SLQDILEN-----DDIK--LDSMFLSSLIADLV-------KGIVYLHS-SEIKSHGHLKS
Gcy2_Spur ---DILEN-----DDIK--LDEMFIASLVSDIV-------KGMRHLHS-TEIRTHGNLKS
Npr5_Spur SLKSILAN-----DDVN--LDLSFKASFIRDLA-------RGMQFLHA-SEIKNHGVLSS
AqueK220_Aque SLYDLLTN-----PHIG--FNKSFRQSFAIDCS-------EGLAYLHG-RKA-IHGRLTS
AqueK221_Aque SLYEVLRN-----PNIV--FDKQFRVLFATDII-------KGLTYLHS-HKL-THGRLSS
AqueK222_Aque SLNDVLQN-----DDIP--LNWGFRFSFVTDIS-------RGLAYLHS-KRI-VHHRLMS
. . . .: :* * *
HSER_Hsap TNCVVDSRMVVKITDFGCNSILP-------------------------------------
CG10738_Dmel SNCLVDSRWVVKLTDFGLFAFKQGIEDSST-------------------------D---M
CG9783_Dmel RNCVVDARWVLKITDYGLNSFYESQGLP-P------------------------------
Gyc32E_Dmel SNCLIDSRWVCQISDFGLHELKAGQEEPNK------------------------------
Gyc76C_Dmel SNCVVTSRWMLQVTDFGLHELRQCAENES------------------------------I
CG4224_Dmel SNCVVDSRFVLKITDFGLHTLRRTRFDLES-------------------------DGGNC
CG3216_Dmel CNCLIDGRFVLKISDFGLRTLTTPSDFV-R------------------------------
KSGC_Mmus SNCLVDSHMQLKLSGFGLWEFKHGSTWRS--------------------------Y---N
HSER_Mmus TNCVVDSRMVVKITDFGCNSILP-------------------------------------
CYGX_Mmus RNCVVDTRFVLKITDHGYAEFLESHCSS-R------------------------------
CYGF_Mmus RNCVVDGRFVLKVTDYGFNDILEMLRLS-E------------------------------
CYGD_Mmus RNCVVDGRFVLKVTDHGHGRLLEAQRVL-P------------------------------
ANPb_Mmus SNCVVDSRFVLKITDYGLASFRSTAEPD-D------------------------------
ANPa_Mmus SNCVVDGRFVLKITDYGLESFRDPE-PE-Q------------------------------
odr-1_Cele STCLIDINWVLKLTLYGVSNFMSDQLDAEN-----I---------------K-VPE---Q
gcy-9_Cele QNCLVDSNWTVKLTNFATEAVIFEKLDHNE-----LRP-----FINTDSESADDVS---D
gcy-8_Cele WSCLIDRNWMIKLTDYGIADPLERWEKSQSISRDGL---------------T-SDD---D
gcy-7_Cele KCCLIDDRWQVKISNYGLQDLRSPE-----------------------------------
gcy-6_Cele KNCLLNDRWQLKITDFGLRIFRTHD-----------------------------------
gcy-5_Cele ATCLVNDSWQVKLTDFGLGALLEEH-----------------------------------
gcy-4_Cele ATCLVNDSWQVKLADFGLQFLQDEEE----------------------------------
gcy-3_Cele ATCLVNDSWQVKLAEFGFDQLLEEI-----------------------------------
gcy-27_Cele ATCLIDINWVLKIALYGVTNFVCDNFDAEN-----I---------------T-MPD---R
gcy-25_Cele SNCVVDSYWVVKLTDFGIKGILKERTNHKE-----L---------------APS-S---A
gcy-23_Cele WSCLIDRNWMIKLTDYGIANPLERWEKLGLISTETL---------------K-EGD---D
gcy-22_Cele STCLVDERWQVKVSFFGLSAIKQYE-----------------------------------
gcy-21_Cele TNCLIDARWMVRLSSFGLRELRGEETWQQE------------------------------
gcy-20_Cele RCCLIDDRWQIKISGFGLKSVRTFE-----------------------------------
gcy-2_Cele ATCLVNDSWQVKLAEYGMDNLVEEQ-----------------------------------
gcy-19_Cele GTVLVNESWQAKLTDFGLGTLAEEK-----------------------------------
gcy-18_Cele WCCLIDRNWMVKLSDYGIANPLERWEKQGAIEIAAA---------------K-DSD---D
gcy-17_Cele RSCLIDDRWQVKISDFGLNEVRGMD-----------------------------------
gcy-15_Cele TNCLIDARWMVRLSSFGLRELRGEETWQQE------------------------------
gcy-14_Cele RCCLIDDRWQIKISGYGLKSVRTFE-----------------------------------
gcy-13_Cele ECCYINDRWQVKIGSYGLSFMQGVE-----------------------------------
gcy-12_Cele TNCLITSRWTLQIADFGLRELREGIMYDSS------------------------------
gcy-11_Cele SNCIVDAYWRIKLSNYGMEQIRVEEPESKP-----DVFYDLVIF--SNKYN-SKTK---N
gcy-1_Cele ATCLVNDSWQVKLAEYGMDNLVEEQ-----------------------------------
daf-11_Cele HNCMLDSHWIVKLSGFGVNRLLVKWKTSGQ-----I---------------F--TE----
C04H5.4_Cele WSVLIDKNWMLKLTDYAVCDPLKRWEKHGRIN---C---------------K-VDN---E
CYGF_Hsap RNCVVDGRFVLKVTDYGFNDILEMLRLS-E------------------------------
ANPb_Hsap SNCVVDSRFVLKITDYGLASFRSTAEPD-D------------------------------
ANPa_Hsap SNCVVDGRFVLKITDYGLESFRDLD-PE-Q------------------------------
CYGD_Hsap RNCIVDGRFVLKITDHGHGRLLEAQKVL-P------------------------------
T01A4.1_Cele SNCVVDSRFVLKVTDFGLHRLHCLEEINLE-------------------------E---I
Npr1_Spur SNCVVDSRFVLKITDFGLTSFREPD-PS-S------------------------------
Npr2_Spur SNCVVDSRFVLKLTDYGLTKFRDTDSNE-R------------------------------
Gcy3_Spur SNLVVDSRWVLKITDFGLHQFRSGSRPPE------------------------------I
Npr3_Spur SNCVVDGRFVLKITDFGIPSFRNSNKYE--------------------------------
Npr4_Spur SNCVVDDRWVVKIADYGLTTFRNQEGSQ-S-------------------------N---A
Gcy1_Spur SNCVVDNRWVLQITDYGLNEFKKGQKQD-V-------------------------D---L
Gcy2_Spur SNCVVDSRWVLKITDFGLVHFKVGQQPPD------------------------------M
Npr5_Spur STCYVDSRWVLKISGFGLLSFNILKEDVMK-------------------------Q----
AqueK220_Aque NNCVIDQHWNLKLT----------------------------------------------
AqueK221_Aque VTCVIGNLWKLKLTDY--------------------------------------------
AqueK222_Aque TNCVIDDRWVVKITDYG-------------------------------------------
: ::
HSER_Hsap --------PKKDLWTAPEHLR----------QAN-----------------ISQKGDVYS
CG10738_Dmel QHMS--AKCLKLLYRAPELLR----------QGPS------------SLVMGTQRGDAYS
CG9783_Dmel R--T--RSAKELLWTAPELLR----------NMKLH----QHHHQHGRIQLGTQLGDVYS
Gyc32E_Dmel S--E--LELKRALCMAPELLR----------DAYR-------------PGRGSQKGDVYS
Gyc76C_Dmel -GEH--QHYRNQLWRAPELLR----------NHI----------------HGSQKGDVYA
CG4224_Dmel N-SH--AYWSKLLWTAPELLR----------VEHN------------RPPEGTQKGDVYA
CG3216_Dmel D--Q--NYYLKLLWIAPELLP----------LTTIP-----------GCCPATQRGDVYS
KSGC_Mmus Q-EA--TDHSELYWTAPELLR----------LRES-------------PCSGTPQGDVYS
HSER_Mmus --------PKKDLWTAPEHLR----------QAT-----------------ISQKGDVYS
CYGX_Mmus P--Q--PAPEELLWTAPELLR----------GPG----------------KATFKGDVFS
CYGF_Mmus E--E--PSEEELLWTAPELLR----------APGGI-------------RLGSFAGDVYS
CYGD_Mmus E--P--PSAEDQLWTAPELLR----------DPSLE-------------RRGTLAGDVFS
ANPb_Mmus S-H---ALYAKKLWTAPELLS----------GNP-------------LPTTGMQKADVYS
ANPa_Mmus G-H---TLFAKKLWTAPELLR----------MAS-------------PPARGSQAGDVYS
odr-1_Cele AAHM--ITYPQYVCFPPEHIR----------EYDDSGK--Q----PPRVVRGSPKGDIYC
gcy-9_Cele PTKD--FARKKYLQQAPEIIR----------EIVTTKT----------IPEGSQSADIYA
gcy-8_Cele KSQA--TQATSILYESPEMLK----------NREKNRVRRVDQDWMRQTQTRRQLGDVYA
gcy-7_Cele ---M--YEKKDLLWSAPELLR----------AEDI---------------KGSKEGDVYS
gcy-6_Cele ---Q--YNKSDRLWTSPELLR----------TDDI---------------LGSREGDIYS
gcy-5_Cele ---T--PSKKRLLWAAPEVLR----------GSLT-------------IHQMDPSADVYS
gcy-4_Cele ---K--PFKKNMLWAAPEVIR----------GSLS-------------IEQMDSSADIYS
gcy-3_Cele ---T--PTKRRLLWAAPEVLR----------GSLT-------------VSQMDPSADVFS
gcy-27_Cele SDYT--ISYAQYVCFPPEHIR----------EYDATGK--L----PTRFVRGSKQGDIYC
gcy-25_Cele FDVD--AIHYKYLQLAPEHIS----------AILEKLE----------EPRGTVEGDIYQ
gcy-23_Cele KSGS--AQKTSLLYQPPEMLK----------NKESNRTRRMDQSWVKQSQARRQMGDIYA
gcy-22_Cele ---V--KEQRDFLHTAPEHIR----------DTNL---------------PITKEMDIYS
gcy-21_Cele -DDV--QEGKDQLWTSPELLR----------WSTGLSQ---------CGVLLVQKSDVYS
gcy-20_Cele ---N--PKKEDLLWASPEYLR----------NEDQ---------------ERLPEGDIYS
gcy-2_Cele ---T--PPKKRLLWVAPEVLR----------GSLS-------------VSQMEPSADIYS
gcy-19_Cele ---K--PMKRRQLWMAPEVIR----------GTLL-------------PHQIEKSADIYS
gcy-18_Cele KSQA--SQATSIIYMAPELLK----------NRETNKRRGMDQSWVKQSMLRRQAGDIYS
gcy-17_Cele ---K--LSTENMLWWAPEVLR----------GLE----------------QRSKEADIYS
gcy-15_Cele -DDV--QEGKDQLWTSPELLR----------WSTGLSQ---------CGVLLVQKSDVYS
gcy-14_Cele ---N--PKKEDLLWTPPENLR----------NENE---------------ERLPEGDIYS
gcy-13_Cele ---K--RTEDGLLHTAPEVLR----------EGLT---------------SGTQAGDVYS
gcy-12_Cele ---Y--NIWENFLWTAPEAMT----------INGSL-A---------ISNPPTPKADAYS
gcy-11_Cele P-IK--KFSTDLLWFAPEIIR----------RYAVKHD---------LSKLELAKADIYS
gcy-1_Cele ---T--PPKKRLLWVAPEVLR----------GSLS-------------VSQMEPSADIYS
daf-11_Cele -DHTPVIKSEELHYFDPAMKKIWKNYADRNERALITPQ-------------FGKKCDMYS
C04H5.4_Cele AEKQ--WQKMASLYVPPEIRT----------ANEKNRLKRMDQKWQGQTILKRQQSDIYA
CYGF_Hsap E--E--SSMEELLWTAPELLR----------APRGS-------------RLGSFAGDVYS
ANPb_Hsap S-H---ALYAKKLWTAPELLS----------GNP-------------LPTTGMQKADVYS
ANPa_Hsap G-H---TVYAKKLWTAPELLR----------MAS-------------PPVRGSQAGDVYS
CYGD_Hsap E--P--PRAEDQLWTAPELLR----------DPALE-------------RRGTLAGDVFS
T01A4.1_Cele G-EH--AYYKKMLWTAPELLR----------DSN-------------APPMGTQKGDIYS
Npr1_Spur --S---TYFAGRLWTAPELLR----------LPE-------------IPSGGTQKGDVYS
Npr2_Spur Q-TS--KNEQKMLWQAPETLR----------SAN-------------Q--QPTQKGDIYS
Gcy3_Spur -GEH--AKYEKLLWRAPELLR----------DPAP-------------RPEGTQKGDMYS
Npr3_Spur ---D---NNYKLLWRAPERLR----------DPF-------------S--PPSKEGDLYA
Npr4_Spur G-GY--RSKAMQVYLPPENRS----------NTY---------------TLVTQATDVYS
Gcy1_Spur -GDH--AKLARQLWTSPEHLR----------QEGS------------MPTAGSPQGDIYS
Gcy2_Spur -GEH--AYYQDLLWKAPEVWE----------------------------PQGTQKGDVYS
Npr5_Spur KDPE--VKFSKMLWTAPEHLR----------GEML-------------PSKGSQKGDVYS
AqueK220_Aque ------------------------------------------------------------
AqueK221_Aque ------------------------------------------------------------
AqueK222_Aque ------------------------------------------------------------
HSER_Hsap YGIIAQEIILRKETFYTLS--CR-D-------------RN-EKIFR--V-ENS----NGM
CG10738_Dmel FGILLYEMHVRRGPFGETG----LT-------------PM-QCLQK--V-LQPQD---YL
CG9783_Dmel FGIIMQEVVVRGEPYCMLS----LS-------------PE-EIIVK--I-KK-----P-P
Gyc32E_Dmel FGILLYEMIGRKGPWGDTA----YS-------------KE-EIIQF--V-KCPEM--LQH
Gyc76C_Dmel FAIIMYEIFSRKGPFGQIN----FE-------------PK-EIVDY--V-KKLPL--KGE
CG4224_Dmel FGIIVHEITTRQGPFYLGRCAYEKS-------------PQ-EIIEL--V-KGYNP-HRMQ
CG3216_Dmel FGIILEEIVNRGGPYQEAR--QQMD-------------VH-TILHK--V-RQ-------C
KSGC_Mmus FAILLRDLIHQQAHGPFED--LEAA-------------PE-EIISR--I-KDPR----AP
HSER_Mmus FAIIAQEIILRKETFYTLS--CR-D-------------HN-EKIFR--V-EN-----SYG
CYGX_Mmus LAIILQEVLTRDPPYCSWG----LS-------------AE-EIIRK--V-AS-----P-P
CYGF_Mmus FAIIMQEVMVRGAPFCMMD----LP-------------AK-EIIDR--L-KM-----P-P
CYGD_Mmus LAIIMQEVVCRSTPYAMLE----LT-------------PE-EVIQR--V-RS-----P-P
ANPb_Mmus FAIILQEIALRSGPFYLEG--LDLS-------------PK-EIVQK--V-RN-----GQR
ANPa_Mmus FGIILQEIALRSGVFYVEG--LDLS-------------PK-EIIER--V-TR-----GEQ
odr-1_Cele VGMIFYMMVEREDPYHLIH--SVER-------------PNATLIKQ--I-LN-----E--
gcy-9_Cele LGMVLYQILFRVEPFHERN--KSIN----------------KLMET--L-AMAN---DDD
gcy-8_Cele FGLVMYEIIFRALPFPEG---TN---------------QS-ELVEW--L-RD------GS
gcy-7_Cele LGIICAELITRKGVFNMED--RKED-------------PE-EIIYL--L-KK-----GGL
gcy-6_Cele FGIISAELITRSSVFDLEN--RKED-------------AE-EIIYM--L-KK-----GGL
gcy-5_Cele FAIIASEILTKREAWDISN--RKEG-------------AD-EILYM--V-KK-----GGN
gcy-4_Cele FAIVASEILTKREAWDLSR--R----------------KE-EIKYA--V-KK-----GGQ
gcy-3_Cele FAIIASEILTRKEAWDLKE--RKEG-------------YD-EIIYR--V-KK-----GGS
gcy-27_Cele VGMIFYMMIEREDPYRLIH--SVER-------------PGSGLMME--I-LD-----H--
gcy-25_Cele LAMCIYQILFYMRPFAERQ--ESIKVY----SGEIFLKLP-ELAHL--L-S--S---QST
gcy-23_Cele FGMVMHEILFRALPFPNG---TN---------------VS-EVMDY--I-RD------GT
gcy-22_Cele FAIICSELITKKSAWDLEN--ETFD-------------IE-ELVYK--I-KK-----GGR
gcy-21_Cele LAIVLYELFGRLGPWGDEP--ME---------------PR-EIVSL--V-KRE--ALAGK
gcy-20_Cele FGIICAEILTRSSAFDLEN--RKEK-------------PD-VIIYQ--V-KK-----GGH
gcy-2_Cele FAIIASEILTKKEAWDILD--RKED-----------------------------------
gcy-19_Cele LAVIASEVLTRKEAWNMAE--RKDT-------------VD-EIVYR--I-KK-----GGP
gcy-18_Cele FGMVMYEILFRSLPFRDN---TN---------------IS-ELVDY--L-AD------GS
gcy-17_Cele FGIICSEVITRSSAFDLEN--RKEK-------------PE-EIIYQ--L-KK-----GGF
gcy-15_Cele LAIVLYELFGRLGPWGDEP--ME---------------PR-EIVSL--V-KRE--ALAGK
gcy-14_Cele FGIICSEILTRSSAFDLEN--RKEK-------------PD-VIIYQ--V-KK-----GGH
gcy-13_Cele FSIVCSELVGHSSAWNLEN--RKEE-------------AD-EIIFM--V-KR-----GGR
gcy-12_Cele FGIIFHEIFTREGPYKIYV--QRGDVNGEAAPKKDSVECR-ALVEK--TVRRV----YSD
gcy-11_Cele LAIVLYEIYGRQGPFGDDL--LD---------------SD-EIIEQ--L-KFP----DGG
gcy-1_Cele FAIIASEILTKKEAWDILD--RKED-------------CE-EIVYN--V-KK-----GGL
daf-11_Cele FGVILHEIILKKKFVEQLF--DS---------------PR-EEDDSVLI-DDENDAIASR
C04H5.4_Cele FGVIIYEILFRSLPYDEK---VD---------------LT-ELAQK--A-AE------GD
CYGF_Hsap FAIIMQEVMVRGTPFCMMD----LP-------------AQ-EIINR--L-KK-----P-P
ANPb_Hsap FGIILQEIALRSGPFYLEG--LDLS-------------PK-EIVQK--V-RN-----GQR
ANPa_Hsap FGIILQEIALRSGVFHVEG--LDLS-------------PK-EIIER--V-TR-----GEQ
CYGD_Hsap LAIIMQEVVCRSAPYAMLE----LT-------------PE-EVVQR--V-RS-----P-P
T01A4.1_Cele FAIILHEMMFRKGVFALEN--EDLS-------------PN-EIVQR--V-RKPVS--EDQ
Npr1_Spur FGIILQEIMYREGVFYIKD--VDLM-------------PE-EIVKK--V-AN-----GYK
Npr2_Spur VGIIMQEIVTRARPFEEER--SSME-------------ID-EIVKK--L-TE-----TSS
Gcy3_Spur LGIILYEMATRQGPYG--------------------------------------------
Npr3_Spur LGIIMLEIGTRCGPFDEER--KVMD-------------TN-GILEI--L-KST----SSQ
Npr4_Spur YGVILVEIASRNEVIPEDD--YPL---------------D----------------EAWR
Gcy1_Spur FAIILTELYSRQEPFHENE----MD-------------LA-DIIAR--V-KIG-----EV
Gcy2_Spur FGIILYEIAHRQGPFGNCE----LS-------------PK-EIYEK--V-KTLG----ET
Npr5_Spur FAIILQEIVTRSHPFYLSG--YT---------------SR-EIIRR--V-IR-----RDE
AqueK220_Aque ------------------------------------------------------------
AqueK221_Aque ------------------------------------------------------------
AqueK222_Aque ------------------------------------------------------------
HSER_Hsap KPFRPDL-FLET-----A----EEKELEVYLLVKNCWEEDPEKRPDFKKIETTLAK-IFG
CG10738_Dmel NPYRPSL-QPLE-----------TAFDCVSECLRECWAERPEDRPD--------------
CG9783_Dmel PLIRPSV-SKG------------AAPPEAINIMRQCWAEQPDMRPDFNSVYE--------
Gyc32E_Dmel GVFRPAL-THTH----------LDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHL------
Gyc76C_Dmel DPFRPEV-ESIIE----A----ESCPDYVLACIRDCWAEDPEERPE--------------
CG4224_Dmel KPFRPEL-EPN-----------GDTKADINGIIRRCWAEDPAERPDFNTLKS--------
CG3216_Dmel NGFRPLI-RER------------ECPPDLLELMEKCWADNQEERPTFSTIRSNIRT-IMK
KSGC_Mmus VPLRPSL-LED------------KGDGRIVALVRECWDESPELRPIFPSIKKT-------
HSER_Mmus KPFRPDL-FLET-----A----DEKELEVYLLVKSCWEEDPEKRPDFKKIESTLAK-IFG
CYGX_Mmus PLCRPLV-SPD------------QGPLECIQLMQLCWEEAPDDRPSLDQIYTQF------
CYGF_Mmus PVYRPVV-SPE------------YAPAECLQLMKQCWAEASEQRPTFDEIFNQF------
CYGD_Mmus PLCRPLV-SMD------------QAPMECIQLMTQCWAEHPELRPSMDLTFD-L------
ANPb_Mmus PYFRPSI-DRT------------QLNEELVLLMERCWAQDPTERPDFGQIKGFI------
ANPa_Mmus PPFRPSM-DLQ------------SHLEELGQLMQRCWAEDPQERPPFQQIRLAL------
odr-1_Cele -NHMPRI-TDDYR----Q-------ENMLLEMCKECWDRNPDKRPTIKKLIES-------
gcy-9_Cele QLIRPTF-PSSNT----G----EGYNLQLLSCIEACWLEIPEMRPPIKKVRTMVNANLKS
gcy-8_Cele KVVKPTI-PQNKV----L-------NMDLSALIQDCWNTTPEMRPSLRRIKLNV------
gcy-7_Cele KSPRPDL-EYDHT---------IEINPALLHLVRDCFTERPSERPSIETVRSQLRG-MNS
gcy-6_Cele QSPRPSL-EHDES---------IEINPALLHLVRDCWTERPSERPDIKQVASQLRS-MNT
gcy-5_Cele RTIRPEL-ILD-----------AEVSPRLTTLVKDCWSEQPEDRPKAEQICKLLSE-MTP
gcy-4_Cele FVLRPDL-HID-----------IEVNQTLLALVKDCWCENPEERPSAENVCKVLFD-MTP
gcy-3_Cele FPIRPDI-ITDV----------PDVNPTLIALVKDCWAEAPEDRPTAENICEQLRD-LMP
gcy-27_Cele -NLMPFI-SNNET----Q-------EDTLLDKCKECWNRDPEKRPTIENLRNA-------
gcy-25_Cele APLHPKV-PE-------G----NSFTMRLLSIIQQCWLYKPAARPALIKITDAVNREFGQ
gcy-23_Cele KTFRPTV-HDRTQ----I-------HPDLVALLLDCWNENPEVRPSIRRVRLNT------
gcy-22_Cele SPPRPSL-ETED-----------EHNGSMSLLVRDCWNENPDQRPTSEQIKTLMKS-MNH
gcy-21_Cele KPFRPDM-AVLKE----S-------PRIVQETVVAAWTEDPLNRPSLHQIKR--------
gcy-20_Cele NPTRPSL-DTGET---------VVINPALLHLVRDCWTERPSERPSIEQVRSHLNG-MKD
gcy-2_Cele -------------------------CEALIALVKDCWAEVPEDRPTAENICSQMKG-LVS
gcy-19_Cele NAPRPEL-DMDG----------VEINHNLLILIRDCWSEEPADRPSADVICNLLKN-MMP
gcy-18_Cele KTVSPEI-QNQMG----L-------HPDLNALLRDCWSENPEIRPSIRRVRLN-------
gcy-17_Cele NAIRPSL-LTDEA---------LEINPALVHLIRDCWTEKPSERPPIDQVRSLLRG-MND
gcy-15_Cele KPFRPDM-AVLKE----S-------PRIVQETVVAAWTEDPLNRPSLHQIKR--------
gcy-14_Cele NPMRPSL-DTGET---------VEINPALLHLIRDCWTERPSERPSIEQVRGHLNG-MRD
gcy-13_Cele TPFRPSL-DDVD----------DDINPAMLHLIRDCWDEDPKQRPNIDMVNKLMKN-MNS
gcy-12_Cele PYFRPDT-SD-------L-----EVQNYVKEVMAACWHHDPYQRPEFKTIKNKLK-----
gcy-11_Cele ALTRPDI-HL-------I----TKAPYPLASVVEKCWVEDPASRPSIQKVREL-------
gcy-1_Cele FPIRPEI-ITDI----------HDVNPALIALVKDCWAEVPEDRPTAENICSQMKG-LVS
daf-11_Cele FP-LPIIIPEGIE----M-------HNDLIKMLENCFGS---VRPDIALA-R--------
C04H5.4_Cele KIQKPSI-QRNKK----L-------NPDLIALLQGIVF-------------VSL------
CYGF_Hsap PVYRPVV-PPE------------HAPPECLQLMKQCWAEAAEQRPTFDEIFNQF------
ANPb_Hsap PYFRPSI-DRT------------QLNEELVLLMERCWAQDPAERPDFGQIKGFI------
ANPa_Hsap PPFRPSL-ALQ------------SHLEELGLLMQRCWAEDPQERPPFQQIRLTL------
CYGD_Hsap PLCRPLV-SMD------------QAPVECILLMKQCWAEQPELRPSMDHTFD-L------
T01A4.1_Cele EPLRPWV-SETGEGEG-D----DALNDTLLSLMVACWSEDPHERPEVSSVRKAVR-----
Npr1_Spur PAFRPTI-DRV------------TCSQEMMTLITNCWKEDSTIRPDYSQLRGT-------
Npr2_Spur PPFRPEI-DPQ------------LCTDEIRSIIQACWEEMPENRPATTDLLSS-------
Gcy3_Spur ------------------------------------------------------------
Npr3_Spur PPFRPSV-PEA------------VWNPVIKDLMKRCWAENPGDRPTASALQTAL------
Npr4_Spur -PPLPDL-EIGDTTDDER----CPCPADYLSLIERCWNINPAQRPHFSQIRQT-------
Gcy1_Spur PPYRPIL-NAVN----------AAAPDCVLSAIRACWPEDPDDRPNIMAVRTMLAP-L--
Gcy2_Spur IPLRPNV-MEIE-----------NGHECLLTVMQECWVEDPEARPDFKTIAN--------
Npr5_Spur PPCRPKI-NEDEF----ETSDMATIFTAIYELMKVCWEELPEDRPDFTAIRA--------
AqueK220_Aque ------------------------------------------------------------
AqueK221_Aque ------------------------------------------------------------
AqueK222_Aque ------------------------------------------------------------
HSER_Hsap LFHD-------QKNES-YM
CG10738_Dmel ------------------F
CG9783_Dmel -----------------RF
Gyc32E_Dmel -----------------KE
Gyc76C_Dmel ------------------F
CG4224_Dmel ------------------M
CG3216_Dmel GFCE-------NLMDD-LL
KSGC_Mmus ------------------L
HSER_Mmus LFHD-------QKNES-YM
CYGX_Mmus -----------------KS
CYGF_Mmus -----------------KT
CYGD_Mmus -----------------FK
ANPb_Mmus -----------------RR
ANPa_Mmus -----------------RK
odr-1_Cele ---------------I-ST
gcy-9_Cele TGKGSLVDQMMKMMEE-YT
gcy-8_Cele --------------ET-YL
gcy-7_Cele SR-------NDNLMDH-VF
gcy-6_Cele NR-------NDNLMDH-VF
gcy-5_Cele RG-------NTNLMDH-VF
gcy-4_Cele NT-------EDNLMDHVFS
gcy-3_Cele KT-------KSNLMDH-VF
gcy-27_Cele ---------------I-AI
gcy-25_Cele DVKGTLIDQMI-EMID-EY
gcy-23_Cele --------------EN-YL
gcy-22_Cele NR-------SSNLMDH-VF
gcy-21_Cele -----------------KL
gcy-20_Cele GR-------KTNLMDH-VF
gcy-2_Cele KQ-------KTNLMDH-VF
gcy-19_Cele -K-------KGNLMDH-VF
gcy-18_Cele ---------------T-EM
gcy-17_Cele GK-------KGNLMDH-VF
gcy-15_Cele -----------------KL
gcy-14_Cele GR-------KSNLMDH-VF
gcy-13_Cele GRSG-----SANLMDHVFS
gcy-12_Cele ---------------P-LF
gcy-11_Cele ------------------L
gcy-1_Cele KQ-------KTNLMDH-VF
daf-11_Cele -----------------KI
C04H5.4_Cele --------------AA-SL
CYGF_Hsap -----------------KT
ANPb_Hsap -----------------RR
ANPa_Hsap -----------------RK
CYGD_Hsap -----------------FK
T01A4.1_Cele -----------------SL
Npr1_Spur ------------------M
Npr2_Spur ------------------M
Gcy3_Spur ------------------K
Npr3_Spur ------------------K
Npr4_Spur ------------------L
Gcy1_Spur -------------QKG-LK
Gcy2_Spur -----------------KL
Npr5_Spur -----------------KL
AqueK220_Aque ------------------D
AqueK221_Aque ------------------G
AqueK222_Aque ------------------I