RYK_Hsap ITLKDVLQEGTFGRIFHGILID-----------EKD-PNKEKQAFVKTVKDQASEIQVTM
lin-18_Cele FQSLPLDMEGTFGEVRYAIWRQVDDVLNGDVDDEEDTFCNQEAVYTKTLKNNASPIQLDR
drl_Dmel VRLSCLVQEGNFGRIYRGTYN------------------DCQEVLVKTVAQHASQLQVNL
dnt_Dmel VRLSSLLQEGTFGRVYRGTYN------------------DTQDVLVKTVAQHASQMQVLL
Drl-2_Dmel LSYEELVKEGTFGRIYAGKLG------------------ESCEALVKTVIDGASLTQVAC
RYK_Mmus ITLKDVLQEGTFGRIFHGILVD-----------EKD-PNKEKQTFVKTVKDQASEVQVTM
Ryk_Spur ITLGEVLLEGTFGRVHQGVLIS-----------AT--GDSEQDVFIKTVTDHSSEEQRHL
AqueK403_Aque ------------------------------------------------------------
AqueK404_Aque GTLKTLLLKTREGG----------------------------------------------
AqueK405_Aque GTLKTLLLKTREGG----------------------------------------------
AqueK406_Aque GTLKTLLLKTREGG----------------------------------------------
RYK_Hsap MLTESCKLRGLH-HRNLLPITHVCI--------EEGEKPMVILPYM-NWGNLKLFLRQCK
lin-18_Cele FLSDALLFYNITPHQNLSQVACVASFGRFDRPETVTDFPLVCYRHQ-GFGNLKKFLTICR
drl_Dmel LLQESMMLYEAS-HPNVLSVLGISI--------EDYATPFVLYAATGSVRNLKSFLQ---
dnt_Dmel LLQEGMLLYGAS-HPGILSVLGVSI--------EDHTTPFVLYPALNNTRNLKQFLL---
Drl-2_Dmel LLQDASLLIGVS-HQHILAPLLANT--------ELPGPPEIAYPHP-SKGNLKMYLQKSR
RYK_Mmus MLTESCKLRGLH-HRNLLPITHVCI--------EEGEKPMVVLPYM-NWGNLKLFLRQCK
Ryk_Spur LVKESCLLQGLS-HKNILPLLHVCF--------SD--PPFILEAFM-KLGNLKQFLKNGR
AqueK403_Aque ------------------------------------------------------------
AqueK404_Aque ---------------------------------------GIMLPGN--------------
AqueK405_Aque ---------------------------------------GIMLPGN--------------
AqueK406_Aque ---------------------------------------GIMLPGN--------------
RYK_Hsap LVE-ANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDD---TLQVKITD
lin-18_Cele HGDKTKGAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCD
drl_Dmel ---DPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDD---QLRVKLTD
dnt_Dmel ---DPACARTVTTIQIVMMASQLSMALDHLHSHGVVHKDIATRNCVIDD---QLRVKLSD
Drl-2_Dmel -----ESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDE---ESYVKICD
RYK_Mmus LVE-ANNPQAISQQDLVHMAIQIACGMSYLARREVIHRDLAARNCVIDD---TLQVKITD
Ryk_Spur IGP-GDKHQAISTRDLVHLAIQITHGMMYLGKKRLVHKDLATRNCVIDE---DYNLKITD
AqueK403_Aque ------------------------------------------------------------
AqueK404_Aque ---NSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHE---NLHVKIGD
AqueK405_Aque ---NSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHE---NLHVKIGD
AqueK406_Aque ---NSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHE---NLHVKIGD
RYK_Hsap NALSRDLFPMDYHCLGDN-------ENRPVRWMALESLVNNEFSSASDVWAFGVTLWELM
lin-18_Cele SALSRDLFPADYHCLGDN-------ENRPLKWMSPEAIANELYSSAADVWSLGVLLWELM
drl_Dmel SALSRDLFPGDYNSLGDG-------EYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMC
dnt_Dmel SSLSRDLFPSDYNCLGDS-------ENRPVKWMSLEALQHKQFSEASDSWAFGVLMWELC
Drl-2_Dmel SALSRDLFPDDYDCLGDN-------ENRPLKWLSLESLQKRVYATQGDVWALGVTYWELV
RYK_Mmus NALSRDLFPMDYHCLGDN-------ENRPVRWMALESLVNNEFSSASDVWAFGVTLWELM
Ryk_Spur NALSRDLFPSDYHCLGDN-------ENRPVKWMAVESLVHKKFSHASDVWSFGVTLWELV
AqueK403_Aque -------------------------------------------------WSFGVVLWEIM
AqueK404_Aque RGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIM
AqueK405_Aque RGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIM
AqueK406_Aque RGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIM
*::** **:
RYK_Hsap TLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLV---
lin-18_Cele SLGGSPHAEIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQV----
drl_Dmel TLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQ---
dnt_Dmel TSAKQPYAEVDPFEMEHYLKDGYRLAQPFNCPDELFTIMAYCWALLPAERPTFAQLQ---
Drl-2_Dmel TLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLL---
RYK_Mmus TLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLV---
Ryk_Spur TLGQTPYMDLDPFEMATFLKSGYRMPQPPSCPDE--------------------------
AqueK403_Aque TRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLRD-----------------------
AqueK404_Aque TRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRL
AqueK405_Aque TRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRL
AqueK406_Aque TRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRL
: . *: :: :: : * *: ** .***:
RYK_Hsap -QCL
lin-18_Cele ---V
drl_Dmel -ICL
dnt_Dmel -SCL
Drl-2_Dmel -SYL
RYK_Mmus -QCL
Ryk_Spur ---L
AqueK403_Aque ---L
AqueK404_Aque KEFY
AqueK405_Aque KEFY
AqueK406_Aque KEFY