MAST2_Hsap FETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF
MAST4_Hsap FETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF
MAST1_Hsap FDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF
MAST3_Hsap FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPF
kin-4_Cele FDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNPF
9978_Tthe FEFIKMLGKGAYGGVYLVKKKNTNDLFAMKVIDCSGKLDKKYLETLQSEKNVFEVITGDW
15619_Tthe FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAILTGDH
19957_Tthe FEFVRHLGAGAYGGVYLVKKKSSGDLFAMKVIDCSGKLDKKYLESLQSERNVFEIITGDY
MAST2_Spur FENIKIISNGAYGAVYLVRHKASLQRFAMKKICKQNIALRNQREQVFAERDILTFAENPF
MAST1_Mmus FDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF
MAST2_Mmus FETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF
MAST3_Mmus FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPF
MAST4_Mmus FETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF
DDB0185113_Ddis FEFIKPITKGGYGKVFLAKKIRTGDIYAIKRLKKSDMIKKNQLDHVKVERNILAYTSNPF
DDB0216386_Ddis YYFIKPISKGGYGQVFLAITKS-NKFFAIKSINKRDTIGKHMVKELMVERNILVQYQNQS
DDB0220700_Ddis FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYKCNF
DDB0220701_Ddis FEIIKPISRGAFGRVYLAQKKKTGDLYAIKVLKKLDTIRKNMVNHVIVERNILAMVQNEF
DDB0229452_Ddis YKHVECIGKGGYGVVCKFINKKTNEIRAIKTIRKDYSA--------LKEINTLKELGGQF
CG6498_Dmel FDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPF
AqueK009_Aque FDVIKIISNGAYGAVYLVRHKQTRMRFAMKKVNKKRMIMKKQVQSVFNERDILTFSENPF
MAST_c-2_Smoe FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPF
MAST_b-2_Smoe FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISARNPF
MAST_b-1_Smoe FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISARNPF
MAST_c-1_Smoe FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPF
: . : *.:* * *:* : * :
MAST2_Hsap VVSMFCSFDT--KRHLCMVMEYVEGGDCATLLKNIG-ALPVDMVRLYFAETVLALEYLHN
MAST4_Hsap VVSMYCSFET--RRHLCMVMEYVEGGDCATLMKNMG-PLPVDMARMYFAETVLALEYLHN
MAST1_Hsap VVGMFCSFET--RRHLCMVMEYVEGGDCATLLKNIG-ALPVEMARMYFAETVLALEYLHN
MAST3_Hsap VVSMFCSFET--RRHLCMVMEYVEGGDCATLLKNMG-PLPVDMARLYFAETVLALEYLHN
kin-4_Cele VVSFYGSFET--RQYLCMLMEYVEGGDCAALLKSAG-TLPVELVRLYVAETILAIEYLHS
9978_Tthe VVKAFYSFVH--ENYLCFVLEYMMGGDFNKILSLYT-ALDQWIVEIYIAELVLAIEYLHS
15619_Tthe VVKALYSFQY--DNYLCFVLDYMSGGDFGQILRWYG-RLDESIAKFYLAEIILAIEYLHS
19957_Tthe VVKAFYSFVH--ETYLCFVLEYMVGGDFTHILEMYT-ALQEWIVQIYMAELILAVEYLHS
MAST2_Spur VVALYCSFET--KKYLCMVMEYVEGGDVATLIKHIG-PLPLETARLYFAEAVLAIEYLHS
MAST1_Mmus VVGMFCSFET--RRHLCMVMEYVEGGDCATLLKNIG-ALPVEMARMYFAETVLALEYLHN
MAST2_Mmus VVSMFCSFET--KRHLCMVMEYVEGGDCATLLKNIG-ALPVDMVRLYFAETVLALEYLHN
MAST3_Mmus VVGMFCSFET--RRHLCMVMEYVEGGDCATLLKNMG-PLPVDMARMYFAETVLALEYLHN
MAST4_Mmus VVSMYCSFET--RRHLCMVMEYVEGGDCATLMKNMG-PLPVDMARMYFAETVLALEYLHN
DDB0185113_Ddis VVKMYYSFQT--KEYYYLVMEYLQGGDCFSLLQMLG-SMDENMAKMIIAETVLALEYLHS
DDB0216386_Ddis IVKLFECFQT--KKKLYMVMEFLHGGDCASLLHSLN-TLEEREAKNIIAQIVNGLEFIHS
DDB0220700_Ddis IVELFSSFQT--DKKLFFVMEFLNGGDCASLLRSFNNNMPEDLTKNIIAQIIICLEYLHN
DDB0220701_Ddis VVKLFYAFQS--TDKLYLVMEYLIGGDCASLLRALG-CFEEHMAKHYIAETVLCLEYLHK
DDB0229452_Ddis TVNIFHTFLSPCKEKVLIEMEYLSGGDCAFHLNDVGVGFPEELAKQYTAETVLCLDFIHE
CG6498_Dmel VVSMYCSFET--KKHLCLVMEYVEGGDCGTLLKNIG-PLPADMARFYFAETVLAVEYLHS
AqueK009_Aque VVGLWCTFQT--RQHLYMVMEYVEGGDVAALLKGVG-YLTLELATMYFSETVLALEYIHS
MAST_c-2_Smoe LVRFFYSFTC--KENLYLVMEYLNGGDMYSMLRNLG-CLDEDMARYYIAELVLALEYLHS
MAST_b-2_Smoe VVRFFYSFTC--SENLYLVMEYLNGGDLYSLLMSMG-CLEEDMARVYIAELVLALEYLHS
MAST_b-1_Smoe VVRFFYSFTC--SENLYLVMEYLNGGDLYSLLMSMG-CLEEDMARVYIAELVLALEYLHS
MAST_c-1_Smoe LVRFFYSFTC--KENLYLVMEYLNGGDMYSMLRNLG-CLDEDMARYYIAELVLALEYLHS
* * : :::: *** : : . :: : ::::*.
MAST2_Hsap YGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIE--------------
MAST4_Hsap YGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIE--------------
MAST1_Hsap YGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIE--------------
MAST3_Hsap YGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIE--------------
kin-4_Cele YGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDA--------------
9978_Tthe MDIVHRDLKPDNMLIDTTGHLKLADFGLSEVGFKTKLNKH-INKTDEDPSQQ--------
15619_Tthe KGIIHRDLKPENVLLDKNGHIKLADFGLSEVGLTNKLNKKVIDETDPEVKK---------
19957_Tthe QGIVHRDLKPDNILLDSKGHVKLADFGLSEVGFNQKLNRT-EKQKV--------------
MAST2_Spur YGIVHRDIKPDNMLITSTGHIKLTDFGLSKIGIMSLTTNLYEGNID--------------
MAST1_Mmus YGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIE--------------
MAST2_Mmus YGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIE--------------
MAST3_Mmus YGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIE--------------
MAST4_Mmus YGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIE--------------
DDB0185113_Ddis HGIVHRDVKPDNLLIDKKGHIKLTDFGLSKVGLLDRQTVVPPSYFSPTLS-GKNNQSSSS
DDB0216386_Ddis CGIIHRDLKVENLIFDKNGIIKIVDFGFSEVGFTGNS-----------------------
DDB0220700_Ddis HGIIHRDLKPDNILIDSNGHIKLADFGLSKFDFVDESCNIKILKN---------------
DDB0220701_Ddis SAIVHRDLKPDNMLIDGLGHIKLTDFGLSKIGIIDDKKMEDSGNTNTN------------
DDB0229452_Ddis KSIIHCDIKPNNMVIDSDGHIKLLDFGNAKK-----------------------------
CG6498_Dmel YGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYID--------------
AqueK009_Aque HGIIHRDLKPDNLLITSEGHIKLTDFGLSKIGLTNYAAHVIEDAWA--------------
MAST_c-2_Smoe LAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGA------------
MAST_b-2_Smoe LGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLINSTDDLAI------------------
MAST_b-1_Smoe LGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLINSTDDLAI------------------
MAST_c-1_Smoe LAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGA------------
::* *:* *::. * ::: *** :.
MAST2_Hsap ------------------------------------------------------------
MAST4_Hsap ------------------------------------------------------------
MAST1_Hsap ------------------------------------------------------------
MAST3_Hsap ------------------------------------------------------------
kin-4_Cele ------------------------------------------------------------
9978_Tthe ------GAGELVGINI-D-----EANKEN--------------------EFK--I-----
15619_Tthe -------------QKM-Y-----EQLRQD--------------------FGI--------
19957_Tthe ------------AVDI-F-----GSKKDN--------------------ESKYKTEYQLL
MAST2_Spur ------------------------------------------------------------
MAST1_Mmus ------------------------------------------------------------
MAST2_Mmus ------------------------------------------------------------
MAST3_Mmus ------------------------------------------------------------
MAST4_Mmus ------------------------------------------------------------
DDB0185113_Ddis SSVSNIGGSNTIGS------------------NISSTNNN-NNNNNTTGA----------
DDB0216386_Ddis ------------------------------------------------------------
DDB0220700_Ddis ------------------------------------------------------------
DDB0220701_Ddis -------------THFNFSTSPTNTSMMDDSST--TGN-PNGNGNTSLNS----------
DDB0229452_Ddis ------------------------------------------------------------
CG6498_Dmel ------------------------------------------------------------
AqueK009_Aque ------------------------------------------------------------
MAST_c-2_Smoe -------------A------------------V---------------------------
MAST_b-2_Smoe ------------------------------------------------------------
MAST_b-1_Smoe ------------------------------------------------------------
MAST_c-1_Smoe -------------T------------------V---------------------------
MAST2_Hsap ------------------------------------------------------------
MAST4_Hsap ------------------------------------------------------------
MAST1_Hsap ------------------------------------------------------------
MAST3_Hsap ------------------------------------------------------------
kin-4_Cele ------------------------------------------------------------
9978_Tthe ----------------------------EIQVEG--------------------------
15619_Tthe EGLKN---ENFIVQLKQNPGCD----LQNSI-----------------------------
19957_Tthe KGVKKENKKDIID--------SKDEELQQKLAEE--------------------------
MAST2_Spur ------------------------------------------------------------
MAST1_Mmus ------------------------------------------------------------
MAST2_Mmus ------------------------------------------------------------
MAST3_Mmus ------------------------------------------------------------
MAST4_Mmus ------------------------------------------------------------
DDB0185113_Ddis --------------------------T---MVGGH---VINTETPIPSNTAIPAKKEKKL
DDB0216386_Ddis ------------------------------------------------------------
DDB0220700_Ddis ------------------------------SFTLY---N---------------------
DDB0220701_Ddis --------------------------SQTNILSPYPQRK---------------------
DDB0229452_Ddis ------------------------------------------------------------
CG6498_Dmel ------------------------------------------------------------
AqueK009_Aque ------------------------------------------------------------
MAST_c-2_Smoe ------------------------------AVEKH---D---------------------
MAST_b-2_Smoe --------------------------------------A---------------------
MAST_b-1_Smoe --------------------------------------A---------------------
MAST_c-1_Smoe ------------------------------AAEKH---D---------------------
MAST2_Hsap ------------------------------------------------------------
MAST4_Hsap ------------------------------------------------------------
MAST1_Hsap ------------------------------------------------------------
MAST3_Hsap ------------------------------------------------------------
kin-4_Cele ------------------------------------------------------------
9978_Tthe ------------------------------------------------------------
15619_Tthe ------------------------------------------------------------
19957_Tthe ------------------------------------------------------------
MAST2_Spur ------------------------------------------------------------
MAST1_Mmus ------------------------------------------------------------
MAST2_Mmus ------------------------------------------------------------
MAST3_Mmus ------------------------------------------------------------
MAST4_Mmus ------------------------------------------------------------
DDB0185113_Ddis LSLAQSKSLFSASSSPSIPSLNLLNSDKPISPMMMGVKGFIPPPPINQQPISNIPTTTTT
DDB0216386_Ddis ------------------------------------------------------------
DDB0220700_Ddis ------------------------------------------------------------
DDB0220701_Ddis ------------------------------------------------------------
DDB0229452_Ddis ------------------------------------------------------------
CG6498_Dmel ------------------------------------------------------------
AqueK009_Aque ------------------------------------------------------------
MAST_c-2_Smoe ------------------------------------------------------------
MAST_b-2_Smoe ------------------------------------------------------------
MAST_b-1_Smoe ------------------------------------------------------------
MAST_c-1_Smoe ------------------------------------------------------------
MAST2_Hsap ---------KDARE---------------FLDKQVCGTPEYIAPEVILRQGY-GKPVDWW
MAST4_Hsap ---------KDARE---------------FLDKQVCGTPEYIAPEVILRQGY-GKPVDWW
MAST1_Hsap ---------KDARE---------------FLDKQVCGTPEYIAPEVILRQGY-GKPVDWW
MAST3_Hsap ---------KDARE---------------FIDKQVCGTPEYIAPEVIFRQGY-GKPVDWW
kin-4_Cele -------V-VETQQ---------------FQDKQLCGTPEYIAPEVILRRGY-GKPVDWW
9978_Tthe -------M-INNEK---------------EQQKRIVGTPDYIAPEIITGESTNNKSLDWW
15619_Tthe ---------RPGGI---------------MKKNRVVGTPDYIPPEVINGESTNNQSIDWW
19957_Tthe -------Q-LQNIV---------------QQKKRIIGTPDYIAPEIINGESSSNPSLDWW
MAST2_Spur ---------RDTKQ---------------FQDQQVCGTPQYIAPEVILRQGY-GKPVDWW
MAST1_Mmus ---------KDARE---------------FLDKQVCGTPEYIAPEVILRQGY-GKPVDWW
MAST2_Mmus ---------KDARE---------------FLDKQVCGTPEYIAPEVILRQGY-GKPVDWW
MAST3_Mmus ---------KDARE---------------FVDKQVCGTPEYIAPEVIFRQGY-GKPVDWW
MAST4_Mmus ---------KDARE---------------FLDKQVCGTPEYIAPEVILRQGY-GKPVDWW
DDB0185113_Ddis TTTTTTGQQSQQQSQQQQQTTPPLPPHNIHRKLSCVGTPDYLAPEILLGIGH-GASADWF
DDB0216386_Ddis --------IKNG-N---------------KKNNKCLGTPYYMSPEVINKRGY-GKTIDWW
DDB0220700_Ddis --------TNNNNT---------------TENQKILGTPYYIPPEVILGKGY-GKTIDWW
DDB0220701_Ddis ------NTLKTPLK---------------KPVKKVVGTPDYLSPEILLGTGH-GQTVDWW
DDB0229452_Ddis --------FNQKKP---------------TSNDGILGSPRYISPEVLLFEPQ-SPAVDYW
CG6498_Dmel ---------SETRQ---------------FSDKQVYGTPEYIAPEVILRQGY-GKPVDWW
AqueK009_Aque ---------KD-YQ---------------FVDQEVYGTPDYIAPEVILGMPY-GFPVDWW
MAST_c-2_Smoe ------SSDSSTKK---------------GRQQKTVGTPDYLAPEILLGTAH-GYPADWW
MAST_b-2_Smoe ------MNDD-REH---------------NQLKSAVGTPDYLAPEILLGTEH-DHAADWW
MAST_b-1_Smoe ------MNDD-REH---------------NQLKSAVGTPDYLAPEILLGTEH-DHAADWW
MAST_c-1_Smoe ------SSDSSTKK---------------GRQQKTVGTPDYLAPEILLGTAH-GYPADWW
*:* *:.**:: . . *::
MAST2_Hsap AMGIILYEFLVGCVPFFGDTPEE---------------LFGQVISDE--IVWPEG-----
MAST4_Hsap AMGIILYEFLVGCVPFFGDTPEE---------------LFGQVISDE--INWPEK-----
MAST1_Hsap AMGIILYEFLVGCVPFFGDTPEE---------------LFGQVISDD--ILWPEG-----
MAST3_Hsap AMGVVLYEFLVGCVPFFGDTPEE---------------LFGQVVSDE--IMWPEG-----
kin-4_Cele ALGIILYEFLVGIVPFFGETPEA---------------LFSKVISED--VEYPEE-----
9978_Tthe SMGVIMYEFLVGLPPFNADSVEE---------------IFDNIKNLR--MEWPEIGDIND
15619_Tthe SLGVMVYEFIAGIPPFNDESVEK---------------IFSNIKKGH--IEWPDVG---Y
19957_Tthe SVGVIMYELLVGIPPFNDSTREK---------------VFENIVNRR--IEFPPTGDPNE
MAST2_Spur SMGVVLYEILVGCPPFFGETPEE---------------LFAQTINVM--IEWPDG-----
MAST1_Mmus AMGIILYEFLVGCVPFFGDTPEE---------------LFGQVISDD--ILWPEG-----
MAST2_Mmus AMGIILYEFLVGCVPFFGDTPEE---------------LFGQVISDE--IVWPEG-----
MAST3_Mmus AMGVILYEFLVGCVPFFGDTPEE---------------LFGQVVSDE--IMWPEG-----
MAST4_Mmus AMGIILYEFLVGCVPFFGDTPEE---------------LFGQVISDE--INWPEK-----
DDB0185113_Ddis SLGVILYEFLCGVSPFNGSSVQE---------------TFQNILQR--NISWPE------
DDB0216386_Ddis ALGIIIFELLSGETPFVGDNQNM---------------IFEKITNYTNEINFPS------
DDB0220700_Ddis SLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHKKKLYFPK------
DDB0220701_Ddis ALGIILYEFLTGSPPFNDDTPEL---------------IFQHILHRDREMEWPE------
DDB0229452_Ddis SLGIVMFELITGTTPFIGETPEE---------------IFESILSRN--TECI-------
CG6498_Dmel SMGIILYEFLIGCVPFFGETTEE---------------LFAHTVNDD--IEWPDS-----
AqueK009_Aque SMGVILYEMMMGVTPFVSSTIQD---------------LFEEITNENLHISFPEE-----
MAST_c-2_Smoe SVGVILFEFLTGIPPFNAEDPQM---------------IFENILNR--NIPWPNI-----
MAST_b-2_Smoe SVGIILYEFLTGVPPFNAEHPQI---------------IFDNILNK--KISWPRV-----
MAST_b-1_Smoe SVGIILYEFLTGVPPFNAEHPQI---------------IFDNILNK--KISWPRV-----
MAST_c-1_Smoe SVGVILFEFLTGIPPFNAEDPQM---------------IFENILNR--NIPWPNI-----
::*::::*:: * ** . : *
MAST2_Hsap -DE-ALPPDAQDLTSKLLHQNPLERLGT---GSAYEVKQHPFF
MAST4_Hsap -D----------------------------------------E
MAST1_Hsap -DE-ALPTEAQLLISSLLQTNPLVRLGA---GGAFEVKQHSFF
MAST3_Hsap -DE-ALPADAQDLITRLLRQSPLDRLGT---GGTHEVKQHPFF
kin-4_Cele -DE-ALPPEAADLCRRLLEKNPAERLGTL--NGAAQLMAHEFF
9978_Tthe G-D-KISPEAYDLIKRLLNPNYKERLGA---KGVKEIKEHAFF
15619_Tthe GED-EMTPEAQDLIKKLLNHDYKKRLGA---NGSQEIKQHKFF
19957_Tthe DEN-CISEEAQDLMEKLLTLDHKQRLGA---RGADEIKKHPFF
MAST2_Spur -DD-ALSDEAMELINGFLQQDPLFRLGT---GGSEDVKGHRFF
MAST1_Mmus -DE-ALPTDAQLLISSLLQTNPLVRLGA---GGAFEVKQHSFF
MAST2_Mmus -DD-ALPPDAQDLTSKLLHQNPLERLGT---SSAYEVKQHPFF
MAST3_Mmus -DE-ALPLDAQDLITRLLRQSPMDRLGT---GGTHEVKQHPFF
MAST4_Mmus -D----------------------------------------E
DDB0185113_Ddis ----DMSPEARDLIDKLLALDPRQRLGF---NGAEEIKSHPFF
DDB0216386_Ddis ----YFSEVAIDLIQKLLQVDPLKRLGA---NGADEVKRHPFF
DDB0220700_Ddis ----KLYPVAIDLIEKLLDPNPSVRLGA---NGVDEVKCHPFF
DDB0220701_Ddis ----EISSEAKDLILKLLNPDPYKRLGA---NGAYEVKTHPFF
DDB0229452_Ddis ----EIQKDAKDLIIKLLDPNPSTRIGS------KDIKNHPYF
CG6498_Dmel -EDWPVQAEAKDIISQLLQQNPRDRLGTQ--SGALEMKEHEYF
AqueK009_Aque -D--EIPDDAQDLVRQLMCFDPMYRLGSTAREGVSGVKSHPFF
MAST_c-2_Smoe -PG-DMSFEAADFIDKLLAEDPNHRLGA---KGAAEVKAHPFF
MAST_b-2_Smoe -PE-DVSYDACDLINRLLTDDPKRRLGY---RGAGEVKAHPFF
MAST_b-1_Smoe -PE-DVSYDAYDLINRLLTDDPKRRLGY---RGAGEVKAHPFF
MAST_c-1_Smoe -PG-DMSFEAADFIDKLLAEDPNHRLGA---KGAAEVKAHPFF