SIK_Hsap MVIMSEFSAD--------------------------------------------------
QSK_Hsap MAAAAASGAGGA--AGAGTGGAG-------------------------------------
QIK_Hsap MVMAD-------------------------------------------------------
CG15072_Dmel MATTPTA--GPAA-----------------------------------------------
kin-29_Cele MAAP--------------------------------------------------------
QIK_Mmus MVMAD-------------------------------------------------------
QSK_Mmus MAAAAASGAGGV--AVAGAGGAG-------------------------------------
SIK_Mmus MVIMSEFSAV--------------------------------------------------
DDB0231454_Ddis MNTHNNNY------QQRSMDSAIVTINDKGYIQSVDRKTCELFGYTIEELQLQKVNILVP
QSK_Spur ------------------------------------------------------------
SIK_Spur MVVMEEKADT--------------------------------------------------
CG4290_Dmel MSTCEAAAAGENGSQAKSEESQP-------------------------------------
AqueK068_Aque LALKLQKETRRV------------------------------------------------
AqueK069_Aque MDL---------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap -PA---------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus -PA---------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis SPYKEQHDTYMQSYFETGVRKIIDKSRVVEGLHKDGSVFPITLSVTEVRIWNKRMFIGSI
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel -PE---------------------------------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap -----------------------------------------GRLLPPPA---PGSPAAPA
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ---------------------------------------------------------APP
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus -----------------------------------------GRLLPPPA---AGPPAAPA
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ESIIDKRLIIYTDVHGIITYCNRNVEELIGYTPAELFGKNVS------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel -----------------------------------------DQKKKQPQHERNEKQLDKP
AqueK068_Aque -----------------------------------------------------------I
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap -AVSPAAGQ---------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel TSSTPQNYK---------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus -AVPPAAVP---------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis -----------------ALMPSP------------HAKSHSEYIEKNYHGGGLWKMLNRV
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel PENLPQNGKTEAKGAEGACSHPPLDALRSSVLLDAGA-----------------------
AqueK068_Aque -TTMDHRLS---------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis RNLPIKHKSGVVFLVSILVTKISTDGIDMFKAIIQTPPKEAVFTINGDGIIKACNFNFTE
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis PMFGYTQKDLLGNTIGLLIPEMSKIIDNTSLNLTDSHDPQLQQQQQTTTTTTTTTTTTS-
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------ASP----------------SIDAI
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------PAG---------------------------------
QSK_Hsap ----------------------PRPPA---------------------------------
QIK_Hsap --------------------------G---------------------------------
CG15072_Dmel -----------------------VPST---------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus --------------------------G---------------------------------
QSK_Mmus ----------------------ARPTA---------------------------------
SIK_Mmus ------------------------PSG---------------------------------
DDB0231454_Ddis --------------TTSTTTSTPTPASIAVSGNNISSPPIDSPLTTPSTPTTFNHSRGVE
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------PT----------------------------------
CG4290_Dmel VACKDALLAQKLFASGGGSTPGPSPTSSAVGAGGIS--------------GK--------
AqueK068_Aque ----------------------IMSTA---------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis SWLGRTRKVDVWHRDGSRFPVNLEIIKLQGENSMFSLQIKKVENPRVYGKDKDKNGGGGG
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis TTENKDGKQLDTIKESKEHRHSKEKKKRKKDRDHNNNNNNNNNNNNNNNEQTSDSSDSSD
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap -------------------------------------------------------Q-GQG
QSK_Hsap -------------------------------------------------------P-ASR
QIK_Hsap -------------------------------------------------------P-RHL
CG15072_Dmel -------------------------------------------------------S-KIS
kin-29_Cele ----------------------------------------------------------RR
QIK_Mmus -------------------------------------------------------P-RHL
QSK_Mmus -------------------------------------------------------P-ASR
SIK_Mmus -------------------------------------------------------T-GQG
DDB0231454_Ddis SDSESRSKKKRSSKKKSRRDDSSSDSSDSETESSSSPHKKNRSSNSSSNSSHSNAPHESS
QSK_Spur ------------------------------------------------------------
SIK_Spur -------------------------------------------------------Q-AKP
CG4290_Dmel -------------------------------------------------------D-LLK
AqueK068_Aque -------------------------------------------------------I-PES
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap QQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK-TRLDSSNLEKIYREVQ
QSK_Hsap GPMPARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDK-TQLDEENLKKIFREVQ
QIK_Hsap QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDK-SQLDAVNLEKIYREVQ
CG15072_Dmel VDKLLRVGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDK-TCLNEEYLNKTFREIA
kin-29_Cele RMGLEKIGLYDVGRAIGKGNFATVRIARHKIAKTKVAIKSIDV-SALDRENLIKLEREVK
QIK_Mmus QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDK-SQLDAVNLEKIYREVQ
QSK_Mmus GSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDK-SQLDEENLKKIFREVQ
SIK_Mmus QQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDK-TRLDSSNLEKIYREVQ
DDB0231454_Ddis YYQPEMIGEYTLGKTLGRGNYGVVKLGTHINTKEEIAIKILYK-EQMTESEFTRCKREIE
QSK_Spur ----------------------------------QVAIKIIDK-TQLEGDNIQKIVREVK
SIK_Spur RRGHIRVGFYDIDRTIGKGNFAVVKLAKHRITKSQVAIKIIDK-SRLDESNLKKVYREVQ
CG4290_Dmel LKEPMRVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDK-SQLDQTNLQKVYREVE
AqueK068_Aque IANQSRIGYYELEKVIGRGNFAIVKLATHTVSKMKVAIKIIDK-SRLDKENLKKVQREVE
AqueK069_Aque -EGCLVGGVYEVKRRLQSGYFGVTWLAENKTTNRDVCLKTFFNESQS-------QRKELV
.:.:* : :*:
SIK_Hsap LMKLLN-----HPHIIKLYQVMETK------------DMLYIVTEFAKNGEMFDYLTSNG
QSK_Hsap IMKMLC-----HPHIIRLYQVMETE------------RMIYLVTEYASGGEIFDHLVAHG
QIK_Hsap IMKMLD-----HPHIIKLYQVMETK------------SMLYLVTEYAKNGEIFDYLANHG
CG15072_Dmel ILKSLR-----HPHITRLYEVMESQ------------SMIYLVTEYAPNGEIFDHLVANG
kin-29_Cele IVKVID-----HPHIVKSYEIMRVD------------NMLYIVSEYCSSGELYETLIEK-
QIK_Mmus IMKMLD-----HPHIIKLYQVMETK------------SMLYLVTEYAKNGEIFDYLANHG
QSK_Mmus IMKMLC-----HPHIIRLYQVMETE------------RMIYLVTEYASGGEIFDHLVAHG
SIK_Mmus LMKLLN-----HPNIIKLYQVMETK------------DMLYIVTEFAKNGEMFDYLTSNG
DDB0231454_Ddis ILKQLY-----HPFINKLLNVLEKD------------DAMFILMDYCQGGDLFHYVNKFG
QSK_Spur VMKLLS-----HPHIIRLYQVMETD------------RYMYLVTEYASGGEIFDHLISHG
SIK_Spur IMKMLS-----HPNVIKLYQVMETK------------SMLYLVTEYASNGEMFD---THG
CG4290_Dmel IMKRLK-----HPHIIKLYQVMETK------------NMIYIVSEYASQGEIFDYIAKYG
AqueK068_Aque IMKQLD-----HPHIIKLYQVMNTT------------QWLYLVTEYASGGEIFDYLIQHR
AqueK069_Aque ILKQLCEGHFEHDYICRVLDVCIDRSPVLNGSGVVLGRIQFVVFEYCSGSDLFNFLCSGP
::* : * : : :: ::: ::. .:::.
SIK_Hsap --------------------HLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDG
QSK_Hsap --------------------RMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDA
QIK_Hsap --------------------RLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDN
CG15072_Dmel --------------------RMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDK
kin-29_Cele -------------------GRVAENVARKWFSETASAVAYLHSQGIVHRDLKAENILLGK
QIK_Mmus --------------------RLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDN
QSK_Mmus --------------------RMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDA
SIK_Mmus --------------------HLSENEARQKFWQILSAVEYCHNHHIVHRDLKTENLLLDS
DDB0231454_Ddis LKGVKMVNSPDIGDQVLMGVPLPEDDTKRIFTQICLGIAHCHKLNIAHRDIKHKNILFDN
QSK_Spur --------------------KMTEREARQKFKQIVAAVHYCHKRGIVHRDLKAENLLLDA
SIK_Spur --------------------RMSEKEAKKKFMQIIAAVEYCHKRHVVHRDLKAENLLLDG
CG4290_Dmel --------------------RMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDL
AqueK068_Aque --------------------KMTESEARKKFKQIVMAVDYCHSRGIVHRDLKAENLLLDE
AqueK069_Aque WEKH------------RKVSNFSEPLARHYFKQVLLGVMYLHERGMYHRDIKPENCVLDD
. * : * : .: . * : ***:* :* ::.
SIK_Hsap NMDIKLADFGFGNFYKSGEPLS------TWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVV
QSK_Hsap NLNIKIADFGFSNLFTPGQLLK------TWCGSPPYAAPELFEGKEYDGPKVDIWSLGVV
QIK_Hsap NMNIKIADFGFGNFFKSGELLA------TWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVV
CG15072_Dmel DMNIKLADFGFSNHYEEGATLK------TWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVV
kin-29_Cele NSNIKIIDFGFSNFQTGDQLLN------TWCGSPPYAAPELLLGNSYDGMKADIWSMGVL
QIK_Mmus NMNIKIADFGFGNFFKTGELLA------TWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVV
QSK_Mmus NLNIKIADFGFSNLFTPGQLLK------TWCGSPPYAAPELFEGKEYDGPKVDIWSLGVV
SIK_Mmus NMDIKLADFGFGNFYKPGEPLS------TWCGSPPYAAPEVFEGKEYEGPQLDVWSLGVV
DDB0231454_Ddis QMNVKIIDFGLSNWSYQE--KM------SFCGTPAYAAPEMLLGINYNGPEVDIWSLGVI
QSK_Spur NMNVKIADFGFSNFFEKDHLLK------TWCGSPPYAAPELFEGREYNGPKADVWSLGVV
SIK_Spur NMNIKIADFGFSNFFVPGEHLA------TWCGSPPYAAPEVFEGQKYDGPQLDIWSLGVV
CG4290_Dmel NMNIKIADFGFSNHFKPGELLA------TWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVV
AqueK068_Aque NSNVKLADFGFSNSFKNEELLK------TWCGSPPYAAPELFEGKEYSGPQADIWSLGVV
AqueK069_Aque NLNLKLTDFGTNKYFADADPMKLIRTKTRGVGTETYRAPEVNSGLDYDPAAADVWSLGVT
: ::*: *** .: *: .* ***: * .* *:**:**
SIK_Hsap LYVLVCGSLPFDG-PNLPT-------------------------------LRQRVLEGRF
QSK_Hsap LYVLVCGALPFDG-STLQN-------------------------------LRARVLSGKF
QIK_Hsap LYVLVCGALPFDG-PTLPI-------------------------------LRQRVLEGRF
CG15072_Dmel LYALVCGALPFDG-KTILE-------------------------------LKSRVVLGKF
kin-29_Cele LYILVAGGFPFPS-DSVNK-------------------------------LKRSVLSGLV
QIK_Mmus LYVLVCGALPFDG-PTLPI-------------------------------LRQRVLEGRF
QSK_Mmus LYVLVCGALPFDG-STLQN-------------------------------LRARVLSGKF
SIK_Mmus LYVLVCGSLPFDG-PNLPT-------------------------------LRQRVLEGRF
DDB0231454_Ddis LYSLVTGKLPFIN-VT-------------------------------------DMIVGKF
QSK_Spur LYVLVSGALPFDG-KTLHN-------------------------------LRARVLSGQF
SIK_Spur LYVLVCGALPFDA-NTLPQ-------------------------------LKERVLAGKF
CG4290_Dmel LYVLVCGALPFDG-STLQS-------------------------------LRDRVLSGRF
AqueK068_Aque LYVMVCGALPFDG-NNLQH-------------------------------LRARVLAGRF
AqueK069_Aque LFFFVGVEQMFAKVQTLDSYSKQIIAPLGIYFPFPLHCSKLDSYLRREADLRGRGVNGSL
*: :* * . : * .
SIK_Hsap R---------------IPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEP-CLP
QSK_Hsap R---------------IPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGD-ADP
QIK_Hsap R---------------IPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEV-PVQ
CG15072_Dmel R---------------IPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSEWQ-SEM
kin-29_Cele K---------------IPYWVSVECADFIRKMLVLNPGKRYTIQNVLQHRWMHIRD-DVQ
QIK_Mmus R---------------IPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEV-PVQ
QSK_Mmus R---------------IPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGD-ADP
SIK_Mmus R---------------IPFFMSQDCETLIRRMLVVDPAKRITIAQIRQHRWMQADP-TLL
DDB0231454_Ddis I---------------LPPSIPLDLQDLIKKMLTVDREHRLNIMNVLNHPWLSKDP-ASS
QSK_Spur R---------------IPFFMSEGCEDLIRHMLILDASRRYTTDQVLNHRWTKGDG-PDP
SIK_Spur R---------------IPFFMSQECEHLIRHMLVINPAKRLSIDQIKNHKWFADCGVPAT
CG4290_Dmel R---------------IPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWMCPEL-LEH
AqueK068_Aque R---------------IPFYMSEECEKLIRKMLQLDPSKRIPLSKVLEHKWMQATP-TTV
AqueK069_Aque KGSALPNESFWSEWECLKVSISPGLRDLLNRIFVLDAGLRITLRDILRHPWVTMED-GMS
: :. ::..:: :: * .: .* *
SIK_Hsap GP-A----------------CP--AFS-------------A-HSYT--SNLGDYDEQALG
QSK_Hsap NF-DR-----------LI--AE--CQQ---------------LKEE--RQVDPLNEDVLL
QIK_Hsap RP-V----------------LY--PQE---------------QENE--PSIGEFNEQVLR
CG15072_Dmel QE-QERFGDMSPGSGTVSKSAS--TSS-------------L-GSAS--DSPPQLDSVVMT
kin-29_Cele KNQAA-----------QL--LEAIPSS-------------S-IEIR--QQSTKLNPTIMM
QIK_Mmus RP-I----------------LY--PQE---------------QENE--PSIGEFNEQVLR
QSK_Mmus NF-DR-----------LI--AE--CQQ---------------LKEE--RQSDPLNDDVLL
SIK_Mmus QQ-D----------------DP--AFD-------------M-QGYT--SNLGDYNEQVLG
DDB0231454_Ddis TL-I----------------S---QNLLHSPPVVHQPQPPQHQKIQPTSIIPNFNE----
QSK_Spur VF-DK-----------MF--AE--H-N---------------V-QS--NQEEPVNELILQ
SIK_Spur QP-V----------------S-----P-------------V-TEIP--KPIGEFNEQALR
CG4290_Dmel V--L----------------IA--KYN-------------L-GAER--QTSVEPSEDILR
AqueK068_Aque EG-PS-----------PL--RS--SPL-----------Y-P-QKTA--SGNLLWNEQVLL
AqueK069_Aque PDIIK-----------ME--MENRCPS-------------A-IRMS--RDASPLL---VG
SIK_Hsap IM---QTLG-VDRQRTVESLQNSS------------------------------------
QSK_Hsap AME---DMG-LDKEQTLQSLRSDA------------------------------------
QIK_Hsap LM---HSLG-IDQQKTIESLQNKS------------------------------------
CG15072_Dmel HML--QLPG-LTADMIAQSVHEQR------------------------------------
kin-29_Cele FM---QQHGKWSEEQIIDAVLGRD------------------------------------
QIK_Mmus LM---HSLG-IDQQKTVESLQNKS------------------------------------
QSK_Mmus AME---DMG-LDKERTLQSLRSDA------------------------------------
SIK_Mmus IM---QALG-IDRQRTIESLQNSS------------------------------------
DDB0231454_Ddis ----------------VETLKNNI------------------------------------
QSK_Spur HMV---SMG-LKTEAIMQSITNQS------------------------------------
SIK_Spur LM---QSLG-IDQQKTIDSLRRDA------------------------------------
CG4290_Dmel IMA--EYVG-IGSDKTRASLKKNT------------------------------------
AqueK068_Aque AIQRLQSSN-FSIEAVKQAVLKKQ------------------------------------
AqueK069_Aque SK---L-LGGVDRVVLRESLSGANKEDIAFPEDSEIWQWSLQIEHLESLQLRISGGDAQE
::
SIK_Hsap -------------------------------Y-NHFAAIYYLLLERLKEYRNAQCAR-PG
QSK_Hsap -------------------------------Y-DHYSAIYSLLCDRHKRHKTLRLGALP-
QIK_Hsap -------------------------------Y-NHFAAIYFLLVERLKSHRSSFPVEQRL
CG15072_Dmel -------------------------------F-DNIYAIYNLLHDKLQQRRRENQRLQHH
kin-29_Cele -------------------------------FESPIFATYELLADKVKKGTLEGTG-EEF
QIK_Mmus -------------------------------Y-NHFAAIYFLLVERLKSHRSSFPVEQRL
QSK_Mmus -------------------------------Y-DHYSAIYSLLCDRHKKHKTLRPGALP-
SIK_Mmus -------------------------------Y-NHFAAIYYLLLERLKEHRSAQPSSRPT
DDB0231454_Ddis -------------------------------L-NNN-------------------NNNN-
QSK_Spur -------------------------------Y-DENSAIYHLLLDKHRRHLKAAEESQSA
SIK_Spur -------------------------------Y-DHYTAIYYLLVERLRLHRCSFPVEGRV
CG4290_Dmel -------------------------------Y-DHVAAIYLLLQDRVSHKKEQSNGLGAS
AqueK068_Aque -------------------------------Y-NDQAALYYMLLHKWEKGQLQIPLNPLV
AqueK069_Aque VMMDLNITLELVRNVLKEPANERHRQVMVDHISNEWIAQLFLIVGFLPKDNSLVLLDEYL
.
SIK_Hsap PAR--QP-----------------------------------------------------
QSK_Hsap SM-PRAL--AF----------QA-----------------------------------PV
QIK_Hsap DGRQRRP-----------------------------------------------------
CG15072_Dmel ASLAYS------------------------------------------------------
kin-29_Cele PRRGSR------------------------------------------------------
QIK_Mmus DGRQRRP-----------------------------------------------------
QSK_Mmus SM-PQAM--TF----------QA-----------------------------------PV
SIK_Mmus PAPTRQP-----------------------------------------------------
DDB0231454_Ddis --NNN-------------------------------------------------------
QSK_Spur AA-LYAL--AL----------GE-------------------------------------
SIK_Spur DVRSRRP-----------------------------------------------------
CG4290_Dmel -ALASST--SASRMIYSSRNDHQ-----------------------------------PT
AqueK068_Aque SQ----L--SY----------QG-------------------------------------
AqueK069_Aque DLNLLNCAVSY----------LQGIELAVTRAAIYTQCTDDGNSEGFEEDMEMEAGVMPL
SIK_Hsap ----RPRSSDLSG----------------------------L-EVP-------------Q
QSK_Hsap NIQ-AEQAGTAMN----------------------------I-SVP-------------Q
QIK_Hsap --------STIAE----------------------------Q-TVA-KAQ---------T
CG15072_Dmel ----RSRKTSITT----------------------------G-VVD-RSE----------
kin-29_Cele -------GSILSG----------------------------K-ANV-DEQ---------P
QIK_Mmus --------STIAE----------------------------Q-TVA-KAQ---------T
QSK_Mmus NLQ-AEQTGTAMN----------------------------L-SVP-------------Q
SIK_Mmus ----QLRSSDLSS----------------------------L-EVP-------------Q
DDB0231454_Ddis ---------NN-------------------------------------------------
QSK_Spur GVA-AQRNLMLGD----------------------------Q-MIP-------------Q
SIK_Spur --------SSIAD----------------------------H-AIM-RTH----------
CG4290_Dmel QQQSQQQSKTIST----------------------------S-SILAKDQCHKRLSRHQT
AqueK068_Aque ----RYSTSSLAS----------------------------FSGVP-------------R
AqueK069_Aque EEEEEEEITTFRDSVTLRGESVTEYDTSSSQSFFNNPISTTA-TAS-GSD---------P
SIK_Hsap -------------------------------EGLSTD-----------------------
QSK_Hsap ------------------------------------------VQ----------------
QIK_Hsap -------------------------------VGLPVTMHSPNMR----------------
CG15072_Dmel ----------------------------------PVKQESL-------------------
kin-29_Cele -------------------------------LTPTISAHQ--------------------
QIK_Mmus -------------------------------VGLPVTLHPPNVR----------------
QSK_Mmus ------------------------------------------VQ----------------
SIK_Mmus -------------------------------EILPCD-----------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------VN----------------
SIK_Spur -------------------------------AGTLTNIN-PHQR----------------
CG4290_Dmel VLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVEVDASGIPL
AqueK068_Aque ------------------------------------------IN----------------
AqueK069_Aque -------------------------------LTIPISMHQ--------------------
SIK_Hsap P--FRPA--LLCPQPQ--------------------------------------------
QSK_Hsap L-----------------------------------------------------------
QIK_Hsap L--LRSA--L-LPQAS--------------------------------------------
CG15072_Dmel -DRLSPL--------SNANASSSALG----------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus L--MRST--L-LPQAS--------------------------------------------
QSK_Mmus L-----------------------------------------------------------
SIK_Mmus P--FRPS--LLCPQPQ--------------------------------------------
DDB0231454_Ddis ---NNNN--ILN------------------------------------------------
QSK_Spur V-----------------------------------------------------------
SIK_Spur NTNARNA--IQVQQQPCVNTSQQMLGFR--------------------------------
CG4290_Dmel PMRYTPLPTAASPAPSNCSSTSSRVGRHSLSSSSPRSHRPVAISLSIDNNPSLANLRCRE
AqueK068_Aque I-----------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap -------------TLVQSVLQ----------------AEMDCE--LQSS-----------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap -------------NVEAFSF-----------------PASGCQ--AEAA-----------
CG15072_Dmel -----------------FG-W------------------SDVA--VDL----------EK
kin-29_Cele --------------LAQLNL-----------------SSPDCD--SDDS-----------
QIK_Mmus -------------NVEAFSF-----------------PTSSCQ--AEAA-----------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus -------------ALAQSVLQ----------------AEIDCD--LHSS-----------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur -------PIQPVQQPTQQIVS----------------ESAQCA--LQRKRKEPPLQPSTC
CG4290_Dmel MMEAGGGPVGAVG----VP-LASKQLHQTISEFIIKQSTEDCRALLQQ----------ST
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque --------------FYNRSI-----------------SSNE------DN-----------
SIK_Hsap -LQ------------WPLFFPVDASCSGVFRPR--------PVSPSS-------------
QSK_Hsap ------------------INPENQ--IVEPDGT---------------------------
QIK_Hsap -FMEEECVDTP-KVNGCLLDPVPP--VLVRKGC--------QSLPSN-------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ----------------------------------------------S-------------
QIK_Mmus -FMEEECVDTP-KVNGCLLDPVPP--VLVRKGC--------QSLPSS-------------
QSK_Mmus ------------------INPENQ--IIEPDGA---------------------------
SIK_Mmus -LQ-------------PLLFPLDTNCSGVFRHR--------SISPSS-------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------TNEDNQ--VIQSNDQ---------------------------
SIK_Spur IFSEGEMVPVPPAVSGTLLEPLPR--MNVRKVR--------SMSPNH-------------
CG4290_Dmel AVAEGK-DDP-PKAESSV-GGVPP--PA-------------STTPTSSTAGPESGSAPCP
AqueK068_Aque ------------------DG----------------------------------------
AqueK069_Aque -M-----------------------------SQGLCLLFFICTCMYC-------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel GEINGKTIKTMSSSSSFDSKANLGQSFRYKMSAEASKLFQTLQESPLPVEQRTKRRVHVG
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------LLDTAIS--EEAR-QG-PGL----EEEQDT
QSK_Hsap ----------------------------------------LN-LDSDEGE----EPSPEA
QIK_Hsap ------------------------------MMETSID--EGLETEG-EAE----EDPAHA
CG15072_Dmel ----------------------------------YGD--FELECLA-RS-----NDPPVN
kin-29_Cele ------------------------------NSDLCDD-SPMS-SMG-PMNHERQFGTPHG
QIK_Mmus ------------------------------MMETSID--EGLETEG-EAE----EDPSQA
QSK_Mmus ----------------------------------------VN-LDSDEGE----EPSPEA
SIK_Mmus ------------------------------LLDTAIS--EEAR-QG-PSL----EEEQEV
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ----------------------------------------LEEMDS-DPE----EPSPEA
SIK_Spur ------------------------------MVVTSID--EGVEADL-PES----ENEMEK
CG4290_Dmel STNGSGGDSGQETNDAKSNGDSRSEKKVLAQGSSSTD--EGCETDQ-G------NDPGSA
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------IIETAIASSQES-MWA-PGSVSTQ-SSQ--
SIK_Hsap QESLP---------------------------S--STG-----------RRHTLAEVSTR
QSK_Hsap LV-------------------------------RYLSM-----------RRHTVGVADPR
QIK_Hsap FEAFQ---------------------------STRSGQ-----------RRHTLSEVTNQ
CG15072_Dmel AQHLSAHAGGG---------------------VNGANT-----------RRHTVGPGD--
kin-29_Cele LDII----------------------------GNRFEN-----------RRHTLCASEQL
QIK_Mmus FEAFQ---------------------------ATRSGQ-----------RRHTLSEVTNQ
QSK_Mmus LV-------------------------------RYLSM-----------RRHTVGVADPR
SIK_Mmus QEPLP---------------------------G--STG-----------RRHTLAEVSTH
DDB0231454_Ddis ---------------------------------SNNNN-----------NNNNNNNSNNN
QSK_Spur LA-------------------------------RYLQI-----------RRNTVIPGDPS
SIK_Spur VGSME---------------------------H-FKSQ-----------RTHSLAESYDI
CG4290_Dmel SQESKGSNGGGSGNANGGPTSHSSSDLTRLVGTTTSGQSH---------KMRSYASSSSS
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque -DDL-----------------------------PDGYQ-LVHEWNVDFSPWHRLIELSST
SIK_Hsap LS-PLT-APCIVVSPSTTASPAEGTSSDS-CLTF-SASKSPAGLSGT--PATQGLL----
QSK_Hsap TE-VME-DLQKL-------LPGFPG-VNP-QAPFLQVAPNVNFMHNL--LPMQNLQPTGQ
QIK_Hsap LV-VMP-GAGKIFSMN--DSPSLDS-VDS-EYDMGSVQRDLNFLEDN--PSLKDIM----
CG15072_Dmel ---------VAHEQAL--ANPNVPP-IDF-KCP-------------------PQ------
kin-29_Cele LS-PN-------------------------------------------------------
QIK_Mmus LV-VMP-GAGKMFSMS--DNPSLES-VDS-EYDMGSAQRDLNFLEDS--PSLKDIM----
QSK_Mmus TE-VME-DLQKL-------LPGFPG-VNP-QGPFLQVAPNMNFTHNL--LPMQSLQPTGQ
SIK_Mmus FS-PLN-PPCIIVSSSATASPSEGTSSDS-CLPF-SASEGPAGLGSG--LATPGLL----
DDB0231454_Ddis NI-INNSNN---------NSNNNNN-INNNINNNNNVNNNVNNNKNN--NNN--------
QSK_Spur GHKVPA-ALRAK-------LPAPPQ-LAG-MGLGGPCISDLTLLNNA--FN---------
SIK_Spur QT-SMA-PSLSDFGIE--PQELSAS-FDS-QEEMEVA-QSFAHV-----QALSD------
CG4290_Dmel SG-VLA-GSAGSYSKS--LSQNLSR-GSS-KSNCSGPYDSLDFALPSGKGSLPSCM----
AqueK068_Aque --------------------------VGS-SSGSMGIVPWQNF------------HG---
AqueK069_Aque LQ-IH-------------------------------------------------------
SIK_Hsap -------GACSP------------------------------------------------
QSK_Hsap LEYKEQSLLQPPTLQLL------NGMGPLGRRASDGGANIQLHAQQLLKR----------
QIK_Hsap -------LANQPS-----------------------------------------------
CG15072_Dmel --CS---DPTQPVPYYPVNLPMLQNQ----------------------PLH---------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus -------LANQPS-----------------------------------------------
QSK_Mmus LEYKEQSLLQPPTLQLL------NGMGPLGRRASDGGANIQLHAQQLLKR----------
SIK_Mmus -------GTSSP------------------------------------------------
DDB0231454_Ddis ---NNNNSN----------------------NNSNNGNN----------I----------
QSK_Spur --LQEQNLLKPPVLEAT------AGQSSFGRRASDGGANMYLNIQQFRKQ----------
SIK_Spur --------RLFP------------------------------------------------
CG4290_Dmel --GSSS-MLATPTPASA-SPAGISSE----------------------HSSERSLYGSHN
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ----------VRLASPFLGSQSA-TPV---------------------------------
QSK_Hsap ----------PRGPSPLVTMTPA-VPAVTPVD-EESSDGEPDQEAVQRYLANRSKRHTLA
QIK_Hsap ----------PRMTSPFISLRPT-NPA---------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ----------PRMTSPFISLRPA-NPA---------------------------------
QSK_Mmus ----------PRGPSPLVTMTPA-VPAVTPVD-EESSDGEPDQEAVQRYLANRSKRHTLA
SIK_Mmus ----------VRLASPFLGSQSA-TPV---------------------------------
DDB0231454_Ddis ----------PNSSNNT-------------------------------------------
QSK_Spur ----------LQ--TTVRTSQPGDIDATGQVQEDENSDGEPDEEAIRRYLDKGRCRHTIG
SIK_Spur ----------SNCNSPDLTQQQT-EPM---------------------------------
CG4290_Dmel SCIHMPGALPLGLGLPQSSASTP-TP----------------------------------
AqueK068_Aque -----------------PS-------LAPPTM-NNASDSTMDA-NLQRY-LNQGRRHTLG
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap MTNPTAEIPPDLQRQLGQ---QPFRSR----------------VWPPHLVPDQHRST---
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus MTSPTAEIPPDLQRQLGQ---QSFRSR----------------VWPPHLVPDQHRST---
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ----NSIINNNLY-----------------------------------------------
QSK_Spur PDVLTNNDMPLVSR-------------------------------------PRHNRF---
SIK_Spur -----------------------------------IP-----------------PP--AP
CG4290_Dmel ------------------------------------------------------NP--TP
AqueK068_Aque TAHNMLIIPPEDMNRLRKINESSSSQASSGFGSSSTNVPPVHPEMQPHIIPTLSTGIEE-
AqueK069_Aque ----------------------------------------------------------E-
SIK_Hsap -----LQAQGGLGGA--VLLP-VS---FQEGRRASDTSLTQGLKAFR-QQL---------
QSK_Hsap ----------YKDSNT-LHLPTER---FSPVRRFSDGAA--SIQAFK-AHL---------
QIK_Hsap -----MQALSSQKREVHNRSP-VS---FREGRRASDTSLTQGIVAFR-QHL---------
CG15072_Dmel -------NLT-IKDQHLLKPP-VVMGASSFGRRASDGGANLHIY----------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus -----MQALSSQKREAHNRSP-VS---FREGRRASDTSLTQGIVAFR-QHL---------
QSK_Mmus ----------YKDSNT-LHLPTER---FSPVRRFSDGAA--SIQAFK-AHL---------
SIK_Mmus -----LQTQAGLGTA--VLPP-VS---FQEGRRASDTSLTQGLKAFR-QQL---------
DDB0231454_Ddis -----NQSLSPQNNNIYQHSP-QHQ---QHQHQQQHSPQ---------------------
QSK_Spur ----------LQPERS-LHLFAS-----TNARRASDGMP--NLQYYQRERL---------
SIK_Spur P-QAMFQHSASLDR-SGSHSP-VS---FREGRRASDGLIAQTGLSYR-QVSPTPLAQ---
CG4290_Dmel ------PPNGGGVTFLDKRSP-IH---FREGRRASDGLVAQGLLSSG-SLLGTSRVYGSY
AqueK068_Aque PKTSIG-SIVSSSRQF-LQLP-RF---FSSKRRASDGGH--YLEAYR-QFL---------
AqueK069_Aque PKQYRAA----------------------------------------A-EF---------
SIK_Hsap -RKTT---------RTKG-----------------FLGLNK-IKGLARQV-CQ-------
QSK_Hsap -EKMG---------NNS-----------------SIKQLQQECEQLQKMY-GGQ-I----
QIK_Hsap -QNLA---------RTKG-----------------ILELNK-VQLLYEQI-GPE-A----
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus -QNLA---------RTKG-----------------ILELNK-VQLLYEQM-GSN-A----
QSK_Mmus -EKMG---------NSS-----------------SIKQLQQECEQLQKMY-GGQ-V----
SIK_Mmus -RKNA---------RTKG-----------------FLGLNK-IKGLARQV-CQ-------
DDB0231454_Ddis ---QQ---------QHQ-----------------QHQHHQQQQQQLQQQH-HQQ-H----
QSK_Spur -ERLAATGGGSSSSQKS-----------------SLKQLHKECQQLQKQF-SSP-I----
SIK_Spur GHKDA---------SLDGHLKT-------------NLNMNS-CSLAADQL----------
CG4290_Dmel RYEQA---------KRHG-----------------WLEIQQ-LQQLQQEA-AVGHSHPHA
AqueK068_Aque -HKRS---------STMYSHQASVEGGVVSAQPTTAKQLLQEKIETDRLY-GR--L----
AqueK069_Aque -CK---------MS----------------GLLCSYGLYQVVCHDQLAMYCRGN-I----
SIK_Hsap ---------------------------APA-----S--RASRG------G-L--------
QSK_Hsap ------DERTLEKTQQQHMLYQQEQH-HQILQQQIQD------SICP-PQ-PSPPLQAAC
QIK_Hsap ------DPNLAPAAPQLQDLASSCPQ-EEVSQQQES-VSTLPA------S-V--------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele -------------------------------------------MMGQ-FP----------
QIK_Mmus ------DPTLTSTAPQLQDLSSSCPQ-EEISQQQES-VSSLSA------S-M--------
QSK_Mmus ------DERTLEKTQQQHMLYQQEQH-HQILQQQIQD------SICP-PQ-PSPPLQVAC
SIK_Mmus ---------------------------SSV--------RTPRG------G-M--------
DDB0231454_Ddis ------HQQ-HQQHQQQHQQQHQQQ-HQ-QHQQHQQS------HQQP-PV--YFPTQIIS
QSK_Spur ------DARA--------------------------------------------------
SIK_Spur -----------------QIVGFSGQQLTEVSKDNAD-LTNLPS------CQV--------
CG4290_Dmel HQHPHQHPHPHPQAYGLEELC----Q-FP----NGQ-FYALPG------K-H--------
AqueK068_Aque ------PRQKLP--HNPHLLSSSGLESSNIIAQMVQPVQPLTSSTLPLPV-PMANLREQC
AqueK069_Aque ------ASFSMR------------------IVNQIVD------GLCK-VF-ISTWC--MC
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ENQPALLTHQLQRLR----IQPSSPPPNHPNNHLFRQPSN--SPP-PMSSAMIQPHGAAS
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele -------------------------PPNLLLNNFSMNPPLGF--P-PMPEG---QAAEFP
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ENQPALLTHQLQRLR----IQPSSPPPNHPSNHLFRQPSN--SPP-PVSSAMITSHGATS
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis DD--FNLTSQLQRT------QPNQQV-SFDTNQSYQQQLQ--QPQIP-------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque QPFH-DITQQQIREQ----LEQLHMSNGSPSDH------G--SLP-HAQSSGVASGGSST
AqueK069_Aque GNDEWALV--LERLTLADRIDAF--QRCLA---DTDLPSINTSKP-TCSDHLLEIVAEYD
SIK_Hsap ------------------------------------------------------------
QSK_Hsap SSQFQGLPSRSAI---FQQQPENCSS--PPNVALTCLGMQQPAQSQQVTIQVQEPVDMLS
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele LP-SLHPA--------FATI----------------------------------PIADLS
QIK_Mmus ------------------------------------------------------------
QSK_Mmus PSQFQGLPSHGAI---FQQQPENCSP--PPSVALTCLGLQQASQSQPVTIQLQEPVDMLS
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ---------HQVL---MQQPPQILSHSNNQPINNYYVGQQ--------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ----------SSI---N--SRKNSSG--NNSIIAQLLAATPPSASPSFPTQMVA-TSMAS
AqueK069_Aque SKSPCGQLKRFAAYIELHDV----------------------------------PYEELS
SIK_Hsap ------------------------------------------------------------
QSK_Hsap NMPGTAAGSSGRGISISP-----------------------------------SAGQMQM
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele K----------------------------------------------MLPVPK-------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus NMAGTAAGSAGRSIPISP-----------------------------------SASQIQI
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque SEYDGASTSNERRYSIQP-----------------------------------SP-----
AqueK069_Aque SLTLSPAGDGDGGDEDSQSTLKEIAYHCYYDIDDRLCSDYNFCIDSSSLPVLYTRDA-CL
SIK_Hsap ------------------------------------------------------------
QSK_Hsap QHRTNLMATLSYGHRPLSKQLSADSAEAHSLNVNRFSPANYDQAHLHPH-----------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele -------------------------SERRASAGETLLPTNFDLTQH--------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus QHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPH-----------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque --HSSLNPPVTRHHRKTLPDL-------HPQLIIVE-----PPANLHPQ-----------
AqueK069_Aque MESSVLIAGESFNEKIYTYQMAV-AVIIESNYADKYNPAI-TQHYMHTCMEHYNDIEICL
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------LF--------------------------------------------------SD
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------LF--------------------------------------------------SD
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ------AS--------------------------------------------------TS
AqueK069_Aque FEIFHHCFTLEDVYYYTPYWCYYDVLTMMCSQFKGDEQLLCEVVLEARWELSLVSECTNE
SIK_Hsap -------------------------------SPFHA-PAQ--------------------
QSK_Hsap QSRGSPSSYSPSTG-VGFSPT-QALKVPPLDQFPTF-PPSAHQ-QPPHYTTSALQQALLS
QIK_Hsap -------------------------------HPQLS-PRQ--SLE-TQYLQHRL------
CG15072_Dmel ----------------------------------------------------------YP
kin-29_Cele --------------------L-ANLPAPPI-SFPTV-EEEGKS-YLSKY-----------
QIK_Mmus -------------------------------HPQLS-PQQ--SLE-TQYLQHRL------
QSK_Mmus QSRGSPSSYSPSTG-VGFPPT-QALKVPPLDQFPTF-PPSAQQ-QPPHYTTSALQQALLS
SIK_Mmus -------------------------------STFHT-PAP--------------------
DDB0231454_Ddis -------------------PI-QQIQ--QLQQQQQL-QQQQQQ-QQQQ------QQQ---
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------E--QELVSWRRF-PAQVQSMERRQYRMHAMKQGVHT
CG4290_Dmel -------------------------------HPLLTLPHHHAHPAQHHHGHHSLFHSGHQ
AqueK068_Aque SSLGES---SPESS-LGATANAIGRRSPPYFQV--G-SPGEVG-SPLHWQERQRKTGM-S
AqueK069_Aque NNKGKC--EDIITGIVDTKPI-SQINSSDIDQMKAV--LSANS-RQLNYTNETLTQ--LS
SIK_Hsap -S-------------------------------------P----GLHG------------
QSK_Hsap PTPP---------DYTRHQ-------------Q-----VPHILQGLLSPRHSLTG-----
QIK_Hsap QK-------------------------------------P----SLLSKAQ---------
CG15072_Dmel ATGTVVGPAQGQQMDTAGY-------------YINPNCG---------------------
kin-29_Cele ---------------------------------------------------------GGK
QIK_Mmus QK-------------------------------------P----NLLPKAQ---------
QSK_Mmus PTPP---------DYPRHQ-------------Q-----VPHILQGLLSPRHSLTG-----
SIK_Mmus -S-------------------------------------S----GLQG------------
DDB0231454_Ddis ----------------QQ------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur EP-------------------------------------P----GHLTHSASLAG-----
CG4290_Dmel ATPLLLEAAAGGDMYGHGC-------------YAPPPPPP----GLYTHHQLGVG-----
AqueK068_Aque LQPS------------------------------------------------HLG-----
AqueK069_Aque RIVE---------YFSLNQSAVSMIIDKQDANT-----FLSVISGLASEN---GTRSLME
SIK_Hsap ----------------------------GAA------------------GSREGWSL--L
QSK_Hsap -------------------HS-----D-IRL-----------PPTEFAQ----------L
QIK_Hsap --------------------N-----T-CQL------------------YCKEPPRS--L
CG15072_Dmel --------------------------T-DPL-----------AVQE--------LSP--L
kin-29_Cele RNTVHCLGNQLGGGIQNPI-PRYQRTPYTKA-----------PPAE----RRSSWASPSL
QIK_Mmus --------------------S-----P-CPV------------------YCKEPPRS--L
QSK_Mmus -------------------HS-----D-IRL-----------PPAEFAQ----------L
SIK_Mmus ----------------------------CTT------------------SNREGRSL--L
DDB0231454_Ddis ---------------------------------------------QQQQ----------Q
QSK_Spur ------------------------------------------------------------
SIK_Spur -------------------QS-----S-LED-----------MPREFPNQMPPNPHT--L
CG4290_Dmel -------------------M------A-VPM-----------SPMQ--------KPP--L
AqueK068_Aque -------------------AS-----S-IEDDFCKGVTIPNLPDP-QSS----------I
AqueK069_Aque SSSVKLKLNKTDTNS-SNMTA-----S-ILI-----------PPAS----IC------NS
SIK_Hsap -EEVL-EQQ--------------------------------RL-----LQLQ--HHP---
QSK_Hsap -IKRQ-QQQ--------------------------------R---Q-QQQQQ--QQQQEY
QIK_Hsap -EQQL-QEH--------------------------------RL-QQKRLFLQ--KQSQLQ
CG15072_Dmel NEQSV-AQM--------------------------------Q-CCQENATGE--CNEELQ
kin-29_Cele -SAQQ-QNHLE------------------------------KLFKQALQTNN--DMTR-L
QIK_Mmus -EQQL-QEH--------------------------------RL-QQKRLFLQ--KQSQLQ
QSK_Mmus -IKRQ-QQH--------------------------------R---Q-QQQQQ--QQQQEY
SIK_Mmus -EEVL-HQQ--------------------------------RL-----LQLQ--HHSSTA
DDB0231454_Ddis -QQQQ-QQQ--------------------------------Q---QQQQQQQ--QQQQ-Q
QSK_Spur ------------------------------------------------------------
SIK_Spur -QRTL-LHQ--------------------------------RL-MQKRQQLQ--KQSQLS
CG4290_Dmel -QQQL-LQH--------------------------------RLLQQKRQLFQ--KQYALE
AqueK068_Aque --VPQ-PLQ--------------------------------Q---Q-QQQHD--ILQQSV
AqueK069_Aque -DTVDDYGLEEEEEYDGSGEDYYYYYYDELCPKGVLNCTQDINGYEYVYYNLYELFGD-C
SIK_Hsap AAAP---------------GCSQA------------------------------------
QSK_Hsap QELFRHMNQGDAGSLAPSLGGQSM----------TER--QALSY-----QNADSYH---H
QIK_Hsap -AYF---------------NQMQI----------AES--------------S-YP--Q--
CG15072_Dmel -SYM---------------QKRGG----------T-Q--R-----------H-T------
kin-29_Cele HKEFKGLSHGCAQSQITNEGSSLA----------CPQIS--IT---------DEYNRQ-H
QIK_Mmus -AYF---------------NQMQI----------AES--------------S-YP--G--
QSK_Mmus HELFRHMNQGDAVSLAPSLGGQNM----------TEQ--QALSY-----QNADSYH-R-H
SIK_Mmus AASS---------------GCQQG------------------------------------
DDB0231454_Ddis QQQQQQQQQQNDPNFQPHLRRIKM----------SKR--D-NSYNKRKSEDGDSYK-KRD
QSK_Spur ------------------------------------------------------------
SIK_Spur -QQF---------------GCMQL----------ERQ--------------S-SF--E--
CG4290_Dmel -AQL---------------AGRHH----------HHQ--Q-----------H-SH--H-H
AqueK068_Aque QQIPIFFNQH-ISLLNPNVANQ-------------------IAH-----QQMSSL--V-H
AqueK069_Aque S-RKLKVPRSCPVVITTSIADSVSSLLSASLPENMTIASLVLSS-----Q--IVTRSE--
SIK_Hsap ------------------------------------PQ-PAPAPF-V--IAP--------
QSK_Hsap HTSP-------QHLLQIRA------QECVSQA----SS-PTPPHGYA--HQPALMHSESM
QIK_Hsap ----------------------------PSQQLPLPRQ-ETPPPS-Q--QAP--------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele NIAPSASSFDPVSIFQKNA------QEVVF-G----QR-PATAIGFS--STS--------
QIK_Mmus ----------------------------PSQQLALPHQ-ETPLTS-Q--QPP--------
QSK_Mmus HTSP-------QHILQIRA------QDCISQG----PS-PTPTHGYA--HQPPLMHSESM
SIK_Mmus ------------------------------------PQ-LSPVPY-V--LAP--------
DDB0231454_Ddis NQSY-------DDILKDEGNKRLRELQTYSEG----DK--------SRQHYNRDSNDNSR
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel H-----------------H------HFGHSLG----PP-PPPAP------AP--------
AqueK068_Aque HIS---------------------------------------------------------
AqueK069_Aque --------NNSTNVTQSLR------ENAML-Q----FKLLMPMNLTE--FVPKCYYWDTL
SIK_Hsap -------------------------CDGP-------------------------------
QSK_Hsap --------------------EEDCSCEGAKDGF-------Q-------------------
QIK_Hsap -------------------------PF---------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus -------------------------SF---------------------------------
QSK_Mmus --------------------EEDCLCEGLKEGF-------P-------------------
SIK_Mmus -------------------------CD---------------------------------
DDB0231454_Ddis DNNRYNNRDNNNNNNSNNNRERDRYKKNKNENFDYGKYKFGKSNEDEENKDKPNIVREKP
QSK_Spur ------------------------------------------------------------
SIK_Spur ---------------------------G--------------------------------
CG4290_Dmel -------------------------EH---------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque --------------------ENVWSDDG--------------------------------
SIK_Hsap ----------GAAPLPS-------------------------------------------
QSK_Hsap DSKSSSTLTKGCHDSP--------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele --------FSGM-STPEQTTRS---------------------------------IDDRV
QIK_Mmus ------------------------------------------------------------
QSK_Mmus D-KSSSTLTKGCHNSP--------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis DFKPSGSLKN--------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur -----------RPPAPN-------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque NVLSSFKIVYQCSGNV--------------------------------------------
AqueK069_Aque --------IETL-VLSDQDVLCNTSHLTSFAVLVDHQGLIESTNIPSAERKALSIVGYIG
SIK_Hsap ---TLLT-------SGLPLLP----------PPLL---QT--------------------
QSK_Hsap ---LLLS-------TGGPGDP----------ESLL---GT--------------------
QIK_Hsap ---SLTQ-------PLSPVLE----------PSSE---QM--------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele RSIVCTL-------PFTEVIDELKASLNILKIPFSESHEM--------------------
QIK_Mmus ---SLTQ-------ALSPVLE----------PSSE---QM--------------------
QSK_Mmus ---LLLC-------TSGPGDP----------EPLL---GT--------------------
SIK_Mmus ---SLLV-------SGIPLLP----------TPLL---QA--------------------
DDB0231454_Ddis -------------------DS----------SSNY---GT--------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur -------------------RT----------DSYK---QA--------------------
CG4290_Dmel ---HLADELYELALLDRPRSG----------TPRL---Q---------------------
AqueK068_Aque ---FTIC-----------------------------------------------------
AqueK069_Aque PGFSLLC-------LI----------IALVIMIALRKRMNTSFLYWIHLNLCISLLLALT
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque VLLVGLETAHHYNWLCSIVAGLLHYLFLCVFAWMLAEGITLFIMVVYVFGIKFLKWQIFI
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque PTAWGIPLFIVAISAGIRHDLYGTDNYCWLSSQKGLVWAFLGPALTVAVVNTIFLVITMI
SIK_Hsap ------------------------------------------------------------
QSK_Hsap ------------------------------------------------------------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus ------------------------------------------------------------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis ------------------------------------------------------------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque QIVRVTWNKLDNNKMSKSKNLQTAKSAIFGAIVLFPLLGITWIIGVFAVSQNTTVFLWLF
SIK_Hsap -----------------GASPVASAAQLLD----------------------THLHIG--
QSK_Hsap -----------------V-----SHAQE----------------------LGIHPY----
QIK_Hsap -----------------QYSPFLSQYQEMQ---LQPLPSTS--GPRAAPPLPTQLQQQQ-
CG15072_Dmel ------------------------------------------------------VGCT--
kin-29_Cele -----------------VYEPQVTE---MR---RLSLPSGVEIGVAVLP-----------
QIK_Mmus -----------------QFSSFLSQYPEMQ---LQPLPSTP--GPQAPPPLPSQLQQHQQ
QSK_Mmus -----------------V-----SQARE----------------------LGIHPY----
SIK_Mmus -----------------GMSPVASAAHLLD----------------------THLHIS--
DDB0231454_Ddis -----------------I-----SSGRN--------------------------------
QSK_Spur --------------------------QE----------------------LQM-------
SIK_Spur -----------------QQHPVLPQYAIN-------------------------------
CG4290_Dmel ------------------HSMTMPGAHAFSQMNLKT----------------SYISQS--
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque TICNSLQGVFILIFHVFKHRAFLT------------LIAR-KCPCMDRF-----------
SIK_Hsap -------------------------------------------T---------------G
QSK_Hsap -------------GHQPTAA-----FS--K-------N--KVPSREPVIGNCMDRSSPGQ
QIK_Hsap PPPPPPPPPPRQPGAAPAPLQ----FSYQT-------C--ELPS---------------A
CG15072_Dmel ---------E-------DLSVAHGSGAGSQ-------S--QAP-----------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus PPPPPPPPPPQQPGAAPTSLQ----FSYQT-------C--ELPS---------------T
QSK_Mmus -------------GHQPTATT----FS--R-------N--KVPSRESVLGNCLERSSPGQ
SIK_Mmus -------------------------------------------A---------------G
DDB0231454_Ddis --------------------------N--NNGEEDEEN--KIK---------LKWHEPAE
QSK_Spur ------------------------------------------------------------
SIK_Spur ---------------DDSSLN----KSLIQ-------CHNEFNQ---------------A
CG4290_Dmel ---------DQVPGAAPNGAGSGGSAAGVS-------C--SAP-----------------
AqueK068_Aque ------------------------------------------------------------
AqueK069_Aque ------------------------------------------------------------
SIK_Hsap PTALPAVP------------------------PPRL---AR-------------------
QSK_Hsap AVELPDHN-GLGYPARP-SVHEHHRPRAL-QRHHTI---QN-------------------
QIK_Hsap ASPAPDYPTPCQYPVDG-AQQSDLTGPDC-PRSPGL---QE-------------------
CG15072_Dmel -TTS----------------------SNMR------------------------------
kin-29_Cele ---------PEHKAH----VEFAIINNDS-PTS---------------------------
QIK_Mmus TSSVPNYPASCHYPVDG-AQQSNLTGADC-PRSSGL---QD-------------------
QSK_Mmus AMELPDHN-GLGYPVRP-LVSEHLRSRTL-QRHHTI---QN-------------------
SIK_Mmus PVALPTGPL-----------------------PQCL---TR-------------------
DDB0231454_Ddis A-KLPTE-KWMLYPFKG-KDQLD--TIYL-HRKKSFLFGRNRDIADIPIDHPSCSSQHAV
QSK_Spur ------------------------------------------------------------
SIK_Spur TSLGSNAP--LHYDTTL---------NQV-PQ-------NF-------------------
CG4290_Dmel PSTAPGTPTVKCKPTTPHGHS--LD-SDYHTSTPVL---SL-------------------
AqueK068_Aque ------HR-GVDFQIHV-QVS----------PHYAI---QN-------------------
AqueK069_Aque --------INVHSSVEA-SRKRSTFRYDN-SRK------KS-------------------
SIK_Hsap --------LAPGCEPLGLL--------------------QGDCEMEDL------------
QSK_Hsap --------SDDAY--VQLDNLPGMS--------LVAGKALSSARMSDAVLSQSSLMGSQQ
QIK_Hsap --------APSSYDPLALSELPG----------------LFDCEMLDA------------
CG15072_Dmel -----------QRRTGL-------------------------LTVTER------------
kin-29_Cele ------------------------------------------------------------
QIK_Mmus --------TASSYDPLALSELPG----------------LFDCEMVEA------------
QSK_Mmus --------SDDAY--VQLDTLPGMS--------LVAGKALSSARMSDAVLSQSSLMGSQQ
SIK_Mmus --------LSPGCDPAGLP--------------------QGDCEMEDL------------
DDB0231454_Ddis IVFRIRKKENPNTGSIKTFILPYIIDLESTNGTFLKGEKIEPA---------------KY
QSK_Spur ------------------------------------------------------------
SIK_Spur --------EAPSYEDS-MD--------------------TSDITVP-V------------
CG4290_Dmel --------FTPNWQSLV-------------------------KPLSES------------
AqueK068_Aque --------ALQLS--LQYMHIG------------------GDSQL---------------
AqueK069_Aque --------SKSGVNLLSLSDNQSS----------------YDTEHVKELDAN--------
SIK_Hsap ------------------------------------------------------------
QSK_Hsap FQD---------GENEECGASLGGHEHPDLSDGSQHLNSSCYPSTCITDILLSY------
QIK_Hsap ------------------------------------------------------------
CG15072_Dmel ------------------------------------------------------------
kin-29_Cele ------------------------------------------EYLC--DQLICR------
QIK_Mmus ------------------------------------------------------------
QSK_Mmus FQD---------EEDEECGVSLG-HEHPGLGDGSQHLNSSRYPATCVTDIMLSH------
SIK_Mmus ------------------------------------------------------------
DDB0231454_Ddis FEL---------RPKD------------K----------ITFGTSTREYILLCE------
QSK_Spur ------------------------------------------------------------
SIK_Spur ------------------------------------------------------------
CG4290_Dmel ------------------------------------------------------------
AqueK068_Aque -----------------------------------------YQSLC--------------
AqueK069_Aque --EAAKLQNFKIVFD------------EKLSADG--------EHCCI-EAVFCGQSISKE
SIK_Hsap --MPC--SLGTFVLVQ
QSK_Hsap KHPEV--SFSMEQAGV
QIK_Hsap --VDP--QHNGYVLVN
CG15072_Dmel --PPG--ALERLTKIL
kin-29_Cele -----LRMIDPSWSSE
QIK_Mmus --VDP--QHNGYVLVN
QSK_Mmus KHPEV--SFSMEQAGV
SIK_Mmus --TSG--QRGTFVLVQ
DDB0231454_Ddis DSIEG--DESEEEDSD
QSK_Spur --------QMQQHQHH
SIK_Spur --SQA--GNNFSFTPC
CG4290_Dmel --PIL--EISEHLESV
AqueK068_Aque --TEL--APHFVPSVQ
AqueK069_Aque TKLEGSEDFEGRQTTS