Protein (view, download) , Domain (view, download)
p70S6Kb_Hsap    -----------------------MAAVFDLDLETEEG--SEG----------------E-
p70S6K_Hsap     MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSED----------------E-
p70S6Kb_Mmus    -----------------------MAAVFDLDLETEEG--SEG----------------E-
p70S6K_Mmus     MRRRRRRDGFYLAPDFRHREAEDMAGVFDIDLDQPEDAGSED----------------E-
R04A9.5_Cele    MKQ---------------------------------------------------------
S6kII_Dmel      MADV-----------------SDPSELFDLELHDLE--LQDDKARDSDD-----------
YBR028C_Scer    MI-------------------------FSLDEELHRVSLDDKKNDIKVDYSSAIYNDIN-
p70RSK_Spur     MAG--------------------HAGVFDLELCEHDEKANEC------------------
Y47D3A.16_Cele  MA-----------------------DVFEFELEGHESQASPQRHAYHYD---------NC
AqueK024_Aque   MSDPD------------------LA--DGLELDQEE-IGSDD----------------E-


p70S6Kb_Hsap    --GEPELSP--ADAC-P--L--AELR-AAGLE--P-------------------------
p70S6K_Hsap     --LEEGGQL--NES-----M--DHGG-VGPYE-LG-------------------------
p70S6Kb_Mmus    --GEPEFSP--ADVC-P--L--GELR-AAGLE--T-------------------------
p70S6K_Mmus     --LEEGGQL--NES-----M--DHGG-VGPYE-LG-------------------------
R04A9.5_Cele    ------------------------------------------------------------
S6kII_Dmel      ----DRIEL--DD----VDL--EPE-LCINLH-QD-------------------------
YBR028C_Scer    --HEQGSSITYEESINHLSVHSNAI-PLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFSI
p70RSK_Spur     --LSDSDDM--QDEGAEG----DSY-LADGA--YE-------------------------
Y47D3A.16_Cele  TEIMEDDHM--YSNVADGQI--SAPPPSSSY--ME-------------------------
AqueK024_Aque   --VEEMMDG--TLIEDNSGL--VSGG-V-NID-ST-------------------------


p70S6Kb_Hsap    -----V-GHYEEVE-----LTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQ-G
p70S6K_Hsap     -----M-EHCEKFE-----ISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVT-G
p70S6Kb_Mmus    -----V-GHYEEVE-----LTESSVNLGPERIGPHCFELLSVLGKGGYGKVFQVRKVQ-G
p70S6K_Mmus     -----M-EHCEKFE-----ISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVT-G
R04A9.5_Cele    ------------VS-----MQKFEKLFYPDDVAPKDFERLKLVGEGGYGKVFQVRKQT-G
S6kII_Dmel      -----T-EGQETIQ-----LCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTA-G
YBR028C_Scer    TGSDAMRTNTNRLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDV---
p70RSK_Spur     -----S-IEVEEVS-----LSEETVNPGTEKVGPTDFQLLKVLGKGGYGKVFQVRKTT-G
Y47D3A.16_Cele  -----D-PMMESIQ-----LCASAINPPNVRVGPEDFQLLKVLGKGGYGKVFQVRKTT-G
AqueK024_Aque   -----A-GCLETLD-----ITPESINNTPEKIGPDCFELLKVLGKGGYGKVFQVRKRTGG
                            ..     :                *:   ::*:*.****: *:.

p70S6Kb_Hsap    TNLGKIYAMKVLRKAKIVRNAKDT-------------------------AHTRAERNILE
p70S6K_Hsap     ANTGKIFAMKVLKKAMIVRNAKDT-------------------------AHTKAERNILE
p70S6Kb_Mmus    TNLGKIYAMKVLRKAKIVCSAKDT-------------------------AHTRAERNILE
p70S6K_Mmus     ANTGKIFAMKVLKKAMIVRNAKDT-------------------------AHTKAERNILE
R04A9.5_Cele    EDKGTIYAMKVITKRKVTGTEKDL-------------------------RHARDERKILE
S6kII_Dmel      RDANKYFAMKVLKKASIVTNQKDT-------------------------AHTRAERNILE
YBR028C_Scer    -NTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILS
p70RSK_Spur     KDSGKIFAMKVLKKAKIVRNQKDT-------------------------AHTKAERNILE
Y47D3A.16_Cele  SDNGQIFAMKVLQKATIVRNQKDT-------------------------AHTKAERNILE
AqueK024_Aque   KDKGRIFAMKVLKKASIVRSKKDT-------------------------MHTRSERNILE
                 : .  :*** : *  :  . .                            ::  **.**.

p70S6Kb_Hsap    SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGH
p70S6K_Hsap     EVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGH
p70S6Kb_Mmus    SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGH
p70S6K_Mmus     EVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGH
R04A9.5_Cele    TINSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEH
S6kII_Dmel      AVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGH
YBR028C_Scer    EIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRF
p70RSK_Spur     AVQHPFIVDLHYAFQTGGKLYLILAYLGGGELFMHLEREGIFMEDTACFYLSEIVLALEH
Y47D3A.16_Cele  AVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEH
AqueK024_Aque   AIQHPFIVSLLYAFQTNGKLYLILDYLSGGELFALLEREGVFLEDTASFYLAEITLAIGH
                 :: * : .* *:*: . ****:*  : ****:  *:...   *  . ** :**  :: .

p70S6Kb_Hsap    LHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAV----------THTFCGTIE
p70S6K_Hsap     LHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTV----------THTFCGTIE
p70S6Kb_Mmus    LHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAI----------THTFCGTIE
p70S6K_Mmus     LHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTV----------THTFCGTIE
R04A9.5_Cele    LHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEK----------TLTFCGTHE
S6kII_Dmel      LHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIV----------THTFCGTIE
YBR028C_Scer    LHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPE
p70RSK_Spur     LHKLGIIYRDLKPENIMLNKQGHVVLTDFGLCKESLEEGSM----------THTFCGTIE
Y47D3A.16_Cele  LHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQK----------THTFCGTIE
AqueK024_Aque   LHSNGIIYRDLKPENIMLNGKGHVVLTDFGLSKESLHGEAT----------TNTFCGTIE
                **  .::******:* :*.  **: ******.*   .                :: ** *

p70S6Kb_Hsap    YMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKL--ALPPYL
p70S6K_Hsap     YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKL--NLPPYL
p70S6Kb_Mmus    YMAPEILVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKL--VLPPYL
p70S6K_Mmus     YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKL--NLPPYL
R04A9.5_Cele    YMAPEMIRKVGHDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKV--RLPPKL
S6kII_Dmel      YMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKL--NLPAYL
YBR028C_Scer    YCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYL
p70RSK_Spur     YMAPEIVSRSGHGKDVDWWSLGALMYDMLTGGPPFTAENRKKTIEKILKGKL--SLPPYL
Y47D3A.16_Cele  YMAPEILMRCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRL--TLPAYL
AqueK024_Aque   YMAPEILQRIGHGKAVDWWSLGTLMYDMLTGAPPFCADNRKKTIDRILHGRL--YLPPYL
                * ***::   .:.:  * ::** *::**: * **: ...     . * : :    :*  *

p70S6Kb_Hsap    TPDARDLVKKFLKRNPSQRIG---------------------GGPGDAADVQRHPFFRHM
p70S6K_Hsap     TQEARDLLKKLLKRNAASRLG---------------------AGPGDAGEVQAHPFFRHI
p70S6Kb_Mmus    TPDARDLAKKFLKRNPTQRIG---------------------GGLGDAADVQRHPFFRHI
p70S6K_Mmus     TQEARDLLKKLLKRNAASRLG---------------------AGPGDAGEVQAHPFFRHI
R04A9.5_Cele    SASGKDLIKRIIKRDPTLRIT--------------------------IPDIKEHEFFEEI
S6kII_Dmel      TPEARDLVRRLMKRQEPQRLG---------------------SGPEDAAAVQIHPFFKHV
YBR028C_Scer    SEGMKDILNALLKKETAKRWNVDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKI
p70RSK_Spur     THEARDLVRKLLKRHISARLG---------------------SGPEDATRIRKHPFFRHV
Y47D3A.16_Cele  SNEARDLIKKLLKRHVDTRLG---------------------AGLSDAEEIKSHAFFKTT
AqueK024_Aque   TADAKDIIKKLLKRHPPNRLG---------------------SGPEDNKPIKEHRFFKMI
                :   :*: . ::*:.   *                               .  * :*.

p70S6Kb_Hsap    NWDDLLAWRV----DPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDT------ALSES-A
p70S6K_Hsap     NWEELLARKV----EPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDS------TLSES-A
p70S6Kb_Mmus    NWDDLLARRV----DPPFRPSLQSEEDVSQFDARFTRQTPVDSPDDT------ALSES-A
p70S6K_Mmus     NWEELLARKV----EPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDS------TLSES-A
R04A9.5_Cele    DWDKLMAHDF----EPPFKPTLANLEDVSHFDESFTSIAPEESPCKA------ITTYTHV
S6kII_Dmel      NWDDVLARRL----EPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDT------TLSES-A
YBR028C_Scer    DWKLLESGQLQKTTLGPIVPVITDLELAENFDTEFTSMSYEETYTDSKPININSVSK-SP
p70RSK_Spur     KWDDVLARKG----EPPITPAVVNEEDVSQFDSKFTKQTPVDSPDDS------MLSES-A
Y47D3A.16_Cele  DWNLVYARQL----EAPFKPNIENDEDTSLFDARFTKMTPVDSPCET------NFSLN-G
AqueK024_Aque   NWEDLFNQKV----EPPFKIPVRGDDDVSQFDTKFTTLLPVDSPVDT------TISAS-A
                .*. :           *:   : . : .. **  **     ::  .:        :

p70S6Kb_Hsap    NQAFLGFTYVAP-SVL--------------------------------------------
p70S6K_Hsap     NQVFLGFTYVAP-SVL--------------------------------------------
p70S6Kb_Mmus    NQAFLGFTYVAP-SVL--------------------------------------------
p70S6K_Mmus     NQVFLGFTYVAP-SVL--------------------------------------------
R04A9.5_Cele    LELFLLFFSMSP-EENGRILNKNKNQSKVMPNLNVKSDMVLTEEEIKKYNGKVLALHRLL
S6kII_Dmel      NLIFQGFTYVAP-SIL--------------------------------------------
YBR028C_Scer    -DMFKGFSYKASGSYL--------------------------------------------
p70RSK_Spur     NQIFLGFTYVAP-SVL--------------------------------------------
Y47D3A.16_Cele  DNPFVGFTYVAP-SVL--------------------------------------------
AqueK024_Aque   DMNFKGFTYIAD-SFL--------------------------------------------
                   *  *   :  .

p70S6Kb_Hsap    -----------------DSIKEGFSFQPK-----------------------LRSP----
p70S6K_Hsap     -----------------ESVKEKFSFEPK-----------------------IRSP----
p70S6Kb_Mmus    -----------------DSIKEGFSFQPK-----------------------LRSP----
p70S6K_Mmus     -----------------ESVKEKFSFEPK-----------------------IRSP----
R04A9.5_Cele    SNKVKKYRKLDENVDYIEFVQKGFMYLLSIGRQEYNKNAMNRSNEFEWKIPKLEEPENIQ
S6kII_Dmel      -----------------EDMHRANRM--P-----------------------ARSP----
YBR028C_Scer    -----------------E------------------------------------------
p70RSK_Spur     -----------------ESMHQKVHHFTK-----------------------VRSP----
Y47D3A.16_Cele  -----------------EMMNKGGHGGIS----------------VA---HLASSM----
AqueK024_Aque   -----------------EDVYSHSVSSPS-----------------------SYR-----
                                 :

p70S6Kb_Hsap    ------------------------------RRLN--SSPRAPVSPLKFSPF-----E--G
p70S6K_Hsap     ------------------------------RRFI--GSPRTPVSPVKFSPG-----DFWG
p70S6Kb_Mmus    ------------------------------RRLN--SSPRTPISPLKFSPF-----E--G
p70S6K_Mmus     ------------------------------RRFI--GSPRTPVSPVKFSPG-----DFWG
R04A9.5_Cele    DVNLFEETEPEKFTKGYIKEELPDKICSTVRKV--IKIPRSALEKVGVRLHD-----DEQ
S6kII_Dmel      ------------------------------RRTPR-QLPDSSFR-LQFPSA-----NV--
YBR028C_Scer    ------------------------------------------------------------
p70RSK_Spur     ------------------------------RKIPGSISPRSAISPAKTPQT-----QFA-
Y47D3A.16_Cele  ------------------------------SRAGAAKSPRKPGDPETASILHGGHSNLFG
AqueK024_Aque   ------------------------------NRP--LRSPHKHLSPVTTETN-----QVFG


p70S6Kb_Hsap    FRPSP-------SL----------------------------------------------
p70S6K_Hsap     RGASA-------ST----------------------------------------------
p70S6Kb_Mmus    FRPSP-------GP----------------------------------------------
p70S6K_Mmus     RGASA-------ST----------------------------------------------
R04A9.5_Cele    -KPTHLLSDDIKTEPIEEATHVNVIQTPSWKPKFQCISDLLKDDTTDFDCEMSLGSSVLF
S6kII_Dmel      -GAN---------APLA-------------------------------------------
YBR028C_Scer    ------------------------------------------------------------
p70RSK_Spur     -------------------FDEDLLTKPS----------------------------SSR
Y47D3A.16_Cele  HGPNS-------EAPQA--FGYGIGSQMT----------------------------TTT
AqueK024_Aque   FNAPS---------PLT----------------------------------------VSS


p70S6Kb_Hsap    ------PEPTE------LPLPPLLP-----------------------------------
p70S6K_Hsap     ------ANPQT------PVEYPMETSGIEQM-----------------------------
p70S6Kb_Mmus    ------PEPME------PSLPPLLPS----------------------------------
p70S6K_Mmus     ------ANPQT------PVEYPMETSGIEQM-----------------------------
R04A9.5_Cele    DRPDS-SLPIKKICPGF-----------PKK----ATEVGGRAEGAVHGWFSYKSYHLIY
S6kII_Dmel      ------MHGHS------Q------RSGMFAR-----------------------------
YBR028C_Scer    ------------------------------------------------------------
p70RSK_Spur     AAPSS-ARPIQ------PIEEAMDTS-----------DG--ASN----------------
Y47D3A.16_Cele  AGGAGIQQPYQSFSGGYPEDDAMDTSTPRASESRETTTGNGSTT----------------
AqueK024_Aque   TAASSLLYTQ---------S-----------TIMEETSG--NST----------------


p70S6Kb_Hsap    ------------------------------------------------------------
p70S6K_Hsap     -----------------------------------DV-----------------------
p70S6Kb_Mmus    -----------------------------------PP-----------------------
p70S6K_Mmus     -----------------------------------DV-----------------------
R04A9.5_Cele    TKLIMIMGSIPSNKRIMSESQVRRELNASFARNCHPTAIGMQKLSERCGIRYKTIFDNFE
S6kII_Dmel      --------------------------------A--TP-----------------------
YBR028C_Scer    ------------------------------------------------------------
p70RSK_Spur     --------------------------------AT--------------------------
Y47D3A.16_Cele  --------------------------------TTRPS-----------------------
AqueK024_Aque   --------------------------------MIKAP-----------------------


p70S6Kb_Hsap    ------------------------------------------------------------
p70S6K_Hsap     ------------------------------------------------------------
p70S6Kb_Mmus    ------------------------------------------------------------
p70S6K_Mmus     ------------------------------------------------------------
R04A9.5_Cele    TIRKDGKIECETNDACCRIREFLSRETDTTSYIEITNEVQTVLEDEIELHLLSRKRFTLG
S6kII_Dmel      ------------------------------------------------------------
YBR028C_Scer    ------------------------------------------------------------
p70RSK_Spur     ------------------------------------------------------------
Y47D3A.16_Cele  ------------------------------------------------------------
AqueK024_Aque   ------------------------------------------------------------


p70S6Kb_Hsap    ----PPPPSTTAPLPI--RP---PS-G-------------------------------TK
p70S6K_Hsap     ----TMSGEASAPLPI--RQ---PNSG-------------------------------PY
p70S6Kb_Mmus    ----SPPPTSTAPLPI--RP---PS-G-------------------------------TK
p70S6K_Mmus     ----TVSGEASAPLPI--RQ---PNSG-------------------------------PY
R04A9.5_Cele    YVHVIMEKTDLAPSYI--RA---QYENWRRKLSTKDRGSWKIGDSEAGLNKYFAKNNKPG
S6kII_Dmel      ----PHHMQTFAPR--P------S-PA-------------------------------QD
YBR028C_Scer    ------------------------------------------------------------
p70RSK_Spur     --------------------------------------------------------A---
Y47D3A.16_Cele  ----NVGSSASTPIPLPKRVIKLPHTH---T-------------------------S-TQ
AqueK024_Aque   ----VVNGSDHSHIPLLK-GINSIRTN---E-V----------------------DK-GN


p70S6Kb_Hsap    K-----------------------------------------------------------
p70S6K_Hsap     K-KQ-------------------------------------AFPM--------------I
p70S6Kb_Mmus    K-----------------------------------------------------------
p70S6K_Mmus     K-KQ-------------------------------------AFPM--------------I
R04A9.5_Cele    V-RQREKIAKKLGLSERQVRNYFNKKRITERKLKVWKDAPKDFLTLSKQTVDEMMKIAEE
S6kII_Dmel      E-----------------------------------------------------------
YBR028C_Scer    ------------------------------------------------------------
p70RSK_Spur     ------------------------------------------------------------
Y47D3A.16_Cele  NAQY-------------------------------------SFML--------------L
AqueK024_Aque   LVSP-------------------------------------GFNLKLS----------PP


p70S6Kb_Hsap    SK---------------------------R-GRGRPGR
p70S6K_Hsap     SK---------------------------RPEHLRMNL
p70S6Kb_Mmus    SK---------------------------K-GRGRSGR
p70S6K_Mmus     SK---------------------------RPEHLRMNL
R04A9.5_Cele    RRKPNDEYIQIANRLGVSHITLCSFIDWQKSIYAGKAK
S6kII_Dmel      MM---------------------------D-VQGLPMV
YBR028C_Scer    -----------------------------------KYF
p70RSK_Spur     -------------------------------AKTSGYR
Y47D3A.16_Cele  LL---------------------------NVSLFFHFF
AqueK024_Aque   AN---------------------------RP-AHLGLS