SMG1_Hsap MSRRA----------PGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDR
CG4549_Dmel MKNAI----------HPE-NCNGAGT---EE----------------------------E
SMG1_Mmus MSRRA----------PGSRLSSGGG--GTKYPRSWNDWQPRTDSASADPDTLKYSSSRDR
smg-1_Cele MITSR-------------------------------------------------------
SMG1_Ddis MNDSN----------SSNDSCNTENNTLTATKNSINNTTTTTTTPNNNVNCLKTSGSIKL
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque MLYTT-------------------------------------------------------
SMG1_Smoe MAEMLLQTLASQVRAAHTFDDHGGG-GGAAV-----------------------------
SMG1_Hsap GGSSSYGLQPSNSAVVSRQR----------------------------HDDTR-------
CG4549_Dmel ASS-------AFHAEIDRVL----------------------------LNNNG-------
SMG1_Mmus GVSSSYGLQPSNSAVVSRQR----------------------------HDDTR-------
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis SAS-SVPFIPGSSASLPSILSNQYKLAASNNVSNNIMMISTPIISSAQQQQQQVPPPQQT
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------------------------------------------------------------
SMG1_Hsap ---------------------------------------------VH-------------
CG4549_Dmel ---------------------------------------------NH-------------
SMG1_Mmus ---------------------------------------------GH-------------
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis TTTTTATATAITPTPITTSQSTSSSMLNLPLKVGKESIETLFRNRFHPKNNIRETVLSSL
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------TAAALPPPPLLPSVQV-CTLLK--------------------------------
SMG1_Hsap --------ADIQN--DEKGGYSVNGGSGENTYGRKSL-----------------------
CG4549_Dmel --------GDSSN--EGGGGNGSGRGGATGSGNIAGLGGS-------ESMWSPGGGKSHD
SMG1_Mmus --------ADIQN--DEKGGYSVNGGSGENTYGRKSL-----------------------
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis QSILIPDLSDTINNTKENIEYFYNMIIDENNYILKLLLLNIINDTKRN--LVVY------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe --------MNLQMLA--AQGLALHPSAALRLLETGSPFSN----------------LRLH
SMG1_Hsap -----GQE--L-RVNNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRI
CG4549_Dmel VAQAFANALLLRNMNHVVGKGQPVVQNHRKAYQCK---GDTINPMANGEDLRLSKIIRRL
SMG1_Mmus -----GQE--L-RINNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRI
smg-1_Cele -------------------------------------------------NNDIGNLIEQF
SMG1_Ddis -NYNQQHQ--L-PIQNTSSPNTPSSTTTTTTTSTKPS--------------------KRG
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe P----CQAI----TSSVAATYVYFLQHGCEKVAVE-------------------------
SMG1_Hsap TREDD-RDRRLATVKQLKEFIQQPENKLVL----VKQLDNIL--AAVH----DVLNESSK
CG4549_Dmel INENN-PTVSLELCSKLDQAVRTPINMGYMTCSFVWILDNML--TLYKQCPPPVLEECSK
SMG1_Mmus TREDD-RDRRLATVKQLKEFIQQPENKLVL----VKQLDNIL--AAVH----DVLNESSK
smg-1_Cele RQRDTPQKERKAILARIEEILQTTKNVESLCVKWTYLLDNLCWPSLTKHDRNDMKTLAGK
SMG1_Ddis DKERE-RGRRNKDKINEKQLQQQQLQQLQL----QQQLDHEG--SSLY------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------------------------------------------------------------
SMG1_Hsap LLQELRQEGACCLGLLCASL--SYE--AEK-IFK-WIFSKFSSSAK--DEVK-----LLY
CG4549_Dmel T-----------LGLI-GFI--NRK--SYP-IYEEFIVKNYKSSKR--MQK--------Y
SMG1_Mmus LLQELRQEGACCLGLLCASL--SYE--AEK-IFK-WIFSKFSSSAK--DEVK-----LLY
smg-1_Cele VIR-----------L-VGVLLFDTE--SYP-EFLIYLGTLYQSVTKKSEETRADIVFSVY
SMG1_Ddis -----------------------------------LPFSSLLSFIK--PD----------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe --------SALCLKREIETL--SRSLAGKKGAMG-LVEAEVVSLLK--FD-------LLL
SMG1_Hsap LCATYKALETVGEKKAFSSVMQLVMTSLQSILENVD--TPELLCKCVKCILLVARCYPHI
CG4549_Dmel MIMALRATLSCDTKCELHMYADKIMLLLKDFLENAE--SADIFIVVSNTLVQFAASYAET
SMG1_Mmus LCATYRALETVGEKKAFSSVMQLVMTSLQSILENVD--TPELLCKCVKCILLVARCYPHI
smg-1_Cele FIVGV--ISQKTENRLIATDTENVEKSLDWIIKVLPNSSISVYNHCLKGFVLVANTFPNV
SMG1_Ddis ----KQQQPQQSQQSQLNEIDQMVRPK--------------SLPK---------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque -------------------IM---------------------------------------
SMG1_Smoe LLMSVRANA-------AESQVQKVKSIINFVLEKSD--P---------------------
SMG1_Hsap FSTNFRDTVDILVGW-HIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDME
CG4549_Dmel FECHFTDVVDIVIGW-QLEAGQPTDLKTHCAQVLEQLTPFFSKQIDFSYGLLDQFVEDIT
SMG1_Mmus FSTNFRDTVDILVGW-HIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDME
smg-1_Cele YAAMFESTLRAIL---------------------TNLPDFNSHEKNFE------------
SMG1_Ddis -DDNDSDNFNIRVLEYN--LKLLIKIYFKVSMYQ----------DSIKTHIFDLYIQINQ
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque --------------------------------------P---------------------
SMG1_Smoe --------FEAPVRW-HSE-----------------------------------------
SMG1_Hsap AYAEDLSHVASGE---SVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSP--------
CG4549_Dmel TLEEG------------------EPANTAERVGAFVGAFNTLLKCLA-RMQI--------
SMG1_Mmus AYAEDLSHVASGE---SVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSP--------
smg-1_Cele ----------------------------------------LLIDTVM-RFSDQLNEKPHL
SMG1_Ddis AISEQQRQLQEKEKESKTSKPIPQPIISL--------VIPTVLVSIGDIIKY--------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe --------------------------LQLAVVQALRRVFSWIVPWEVD------------
SMG1_Hsap --I----RGPPITEAYVTD--VLYRVMRCVTAA-NQVFFSEAVLTAANECVGVLL----G
CG4549_Dmel --F----VGMPTCECIVKM--AVDHLIKIMP----TLHLNTEALVNINELICICLLNNFT
SMG1_Mmus --I----RGPPITEAYVTD--VLYRVMRCVTAA-NQVFFSEAVLTAANECVGVLL----G
smg-1_Cele AEEMVRIIRPDIKKNGLGNMRELKKRMKLTMAL-VKMAKSQKMLEETNQMISEMS----I
SMG1_Ddis --KYATPSPPNLTPTTTTK---MEEEER--------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------VF----------------------
SMG1_Smoe -------------------------------AEGAMEFFG--------------------
SMG1_Hsap SLDP---------SMTIHCDMV---ITYGLDQLE----------------NCQTCGTDYI
CG4549_Dmel GLDP---------IL---LEQV------LLDQVK----------------RMISLTELQR
SMG1_Mmus SLDP---------SMTIHCDMV---ITYGLDQLE----------------NCQTCGTDYI
smg-1_Cele ELEENGGKWSSASLITIVCDVFNELLILGKDDVKLQKGVEESLCNVLKDLNLSNQSTMEK
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------------------------------------------------------------
SMG1_Hsap ISVLNLLTLIVEQINTKL-PSSFVEKLFIPSSKLLFLRYHKEKEVV-AVAH-AV--YQAV
CG4549_Dmel QSVLYLLLCTVRRLRARL-TPSLVHFIFQSNPYMTKVRLRSPGETSYKLLL-RT--CQET
SMG1_Mmus ISVLNLLTLIVEQINTKL-PSSFVEKLFIPSSKLLFLRYHKEKEVV-AVAH-AV--YQAV
smg-1_Cele QAFFNSLAKIVKQLPAESQVKTRVHQIVFNTETGLFTPKN--RDNR-MFGHNMI--YKDL
SMG1_Ddis ------------IINTIL-INEF-----------------KKTDVS-IIES-NLYLFECI
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------------------------------------------KCS-VAMAR-GL--EKGV
SMG1_Hsap LSLK-NIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVV
CG4549_Dmel LLIR-NVPLLQQAYKYLVDDIDACLEKLLITAPRS----------------KARKASVLL
SMG1_Mmus LSLK-NIPVLETAYKLILGEMTCALNNLLHSLQLPDACSEIKHEAFQNHVFNIDNANFVV
smg-1_Cele INLV-SVLLTPTSLNHLQATYTD-LRKI-----MIDSMSRLKQSEDTPYSDNIRWNESIL
SMG1_Ddis LSI------------------------------------------------SVSNEPTIV
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ASLTVRIEVLEW------------------------------------------------
SMG1_Hsap IFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSH
CG4549_Dmel VFHLSALAALAKQTSSIIGMYACKPSILELLLTNCRAHELKFWSKYPAAQQAIFGLLVVH
SMG1_Mmus IFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSH
smg-1_Cele LLFFSSLQSISCAKSSLIVMMGIRPSIFEFFSSELPLTEYWLASNHPEVYHLFITIFVGH
SMG1_Ddis VPNTTTATTATTATTSNTSTAAAATTTTPTLS----------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------VGEFPKWFRKLEGMTLLSSSLFVA------------------------------
SMG1_Hsap CTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSI--ILNLLGI-LLK-KDNLNQDT
CG4549_Dmel CQANHNFRTNS-----SLLRDQELSAENTSPTANSFAS--ILRFLDSVLGQ-AHQLAPQN
SMG1_Mmus CTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSI--ILNLLGI-LLK-KDNLNQDT
smg-1_Cele LKAHDFYIVQS-----DYIVRGDSIGQSIGQTKRDYARKQVVALQKI-INNFGDKLWKKT
SMG1_Ddis -------------TSSSSLSPPASTQSSLSLSSS--------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------------------------------------------------------------
SMG1_Hsap RKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSL--HA
CG4549_Dmel LRVLLQWIQM--LLRECREKIDLLMEQENFRGICRNIAA-TASKLVPLESAACIQ-----
SMG1_Mmus RKLLMTWALEVAVLMKKSETYAPLFSLPSFHKFSKGLLANTLVEDVNICLQACSSL--HA
smg-1_Cele RLMISSWLHSLIATACEHQIGSDSFSQREWVRLRNTVIHQSVLTWNNECVNQALTI--LS
SMG1_Ddis ---------SSAVIAPTTVGYIFKFNKELFRKLI-ALVYSTVVQH-QITLSTVFTT--LV
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ------------------------------------LVAAASDEEHTVRLQASKTFGALL
SMG1_Hsap LS---SSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIP--LDVVLSNNNHTEIQ-
CG4549_Dmel ------TVLDYGLERLEKYPKLLILYRDTALQQL-------------QMLSTNYHAPYF-
SMG1_Mmus LS---SSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIP--LDVVLSNNNHTEIQ-
smg-1_Cele TATKWSELTSDIHRDIADKTKKAKWKEATTIWE-----------------SGDCNTYIR-
SMG1_Ddis LK---GYLNEDQIQKLLNITLFKLSDPSEQVKLSYLTLLSKMVSYFDLNHQKNLNHKVN-
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe RH---KCLSSSQLYSVASAAFEQLGDPDPGIQAAFREVLATCA--LGALWVHGWNSDLDA
SMG1_Hsap --------EISLALRSHMSKAPSN-TFHPQDFSDVISFILYGNS----------------
CG4549_Dmel --------QIYAQLPLHLTLTGGE-SSMPGMASRRVSVWQQRISQYSAVRDNVFRDFFDR
SMG1_Mmus --------EISLALRSHMSKAPSN-TFHPQDFSDVISFILYGNS----------------
smg-1_Cele -Q--SMSTVYQMSQERQQKTITST-SFGAEEFIIITNFLLKQATP--------------T
SMG1_Ddis --------DISLPYKLLIMGSTSQPFFNGQIFKKIFDWIMGIGK----------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe KEEGNFVTKRPLEREKHWRSVLSANRFALQLSPPQVVCILNYISQRP-------------
SMG1_Hsap -HRTGKDNW---LERLF----YSC-----------------------------QR-----
CG4549_Dmel VQKPEQDSLIHCLRELF---VRSC-----------------------------QV-----
SMG1_Mmus -HRTGKDNW---LERLF----YSC-----------------------------QR-----
smg-1_Cele TFKKGQNSW---MDEVLETFTQGC-----------------------------RT-----
SMG1_Ddis -DQPSFDSLTKYLIDLF----DSFNVISILFNEQNKILSQQYLAAQSTMITPPLS-----
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe --QSLPAGW---QQRLV----FNC-----------------------------LKTKSAD
SMG1_Hsap -------LDK-RDQS-TIPRNLL---------KTDAVLWQ-WAIWEAAQFTVLSKLRTPL
CG4549_Dmel -------AP-QDERQMNLSQCTK---------RCQRLAIA-WLQFEAARYCVDQRLRTTV
SMG1_Mmus -------LDK-RDQS-TIPRNLL---------KTDAVLWQ-WAIWEAAQFTVLSKLRTPL
smg-1_Cele -------LEK-PD-S-YVPETFI-------------EKWD-WIINQTANFCIVNKMKTPL
SMG1_Ddis -------LHQIDDRR-KFETLIS---------KSDELIWF-WTVWECSKFCIANRLKSPY
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe DKKQGDGLDR-KEDF-SVVEDAARFDLVESWCCSSNMAAAWFIIQELARHCITVRFRTHL
SMG1_Hsap GRAQDTFQTIEGIIRSLAAHTL---NPDQDVSQWTTADND-E---GHGNNQLRLVLLLQY
CG4549_Dmel GKPQETFLGFEAIIMRHARLLS---GCAKEIERSALDDLSLE---ELLSMQSNLSLLLGF
SMG1_Mmus GRAQDTFQTIEGIIRSLAAHTL---NPDQDVSQWTTADND-E---GHGSNQLRLVLLLQY
smg-1_Cele GKPMQTFAAFENEIKRLAKEVIVRKNSDKKLNKSSTEDPNQSPPLKYSVQWLRVHLLLKL
SMG1_Ddis GSAFQTFEIFEKLLLQLNKDR---------------------------RDFKKIKILLHF
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe GGPTQTFAALERMLLDLPQLVQ---S-----------ESS-A---ANTSELLPMRLLLEL
SMG1_Hsap LENLEKLMYNAYEGCANA--LTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQP
CG4549_Dmel LDALEKLIYNAAEGSAFA--LRPPEKQVAAFFRLNNPTCQSWFNRIRIGVVIIAMHVQQP
SMG1_Mmus LENLEKLMYNAYEGCANA--LTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQP
smg-1_Cele IVVLEKLMNSAIHGGSSVFNLTEIPVSSRQFFTVNAASCEVWLNRVYYPALLVAYFNGYY
SMG1_Ddis MESMEKLIFSTVNGSVLV---QSLNNKETQFFRHNVRVCEDWFSRIRVNLLKASILSSST
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------FTRV--------------
SMG1_Smoe VDSLQRNIYNAYEGSL-V--LEAPSFSSGLFFRANKKVCEEWFARIREALVNASSVIQCH
SMG1_Hsap AVTVRHGFDLLTEMKTTSL----------SQ--GNELE--------VTIMMVVEALCELH
CG4549_Dmel ELVIRYAQQILVNSKT--------------Q--DPTYS--------QAIVYMAWSLVSCQ
SMG1_Mmus AVTVRHGFDLLTEMKTNSL----------TQ--GSELE--------VTIMMVVEALCELH
smg-1_Cele GLVIRFGSNALSHFARQKD---------------GDNDKKIVNGV-CTASLMSLSMAVLG
SMG1_Ddis PDIIRHASLRVQDIQANRFVLD-----SNTA--HFELE--------FCILHLANALQQLN
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe FGTAQHALFRLHDLRPMALAALRDLPRSQAADGGLSLKVKLQQDVFRVLRHGSLALCKLH
SMG1_Hsap CPEAIQGIAVWSSSIVG--------------------------------KNLLWINSVAQ
CG4549_Dmel EADSLRGLRLWARGKSC--------------------------------KSYKWLKYAAD
SMG1_Mmus CPEAIQGIAVWSSSAVG--------------------------------KNLLWINSVAQ
smg-1_Cele EPMEIVGLRRKVREEFGTDM------------------------------GQSLMEALGE
SMG1_Ddis ETESLQGLSNWSDINLNNSDN-NNNNNNKNNNNNNNSTFFNNGNINKYTLKLPWMKGVIL
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ESDSILGLQAWAVTAFAGLILED------------------VHKVSSPLGPVGWMNGLAF
SMG1_Hsap QAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVL
CG4549_Dmel QAAGKRESALAGYRTILAEKE---------------------------------------
SMG1_Mmus QAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVL
smg-1_Cele MANARYETALVALEAVLVTDA---------------------------------------
SMG1_Ddis RSKQKFEESISSLLSVPPM-----------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe EARGEFERAAAHYSQLFQSEE---------------------------------------
SMG1_Hsap SKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTS---L--NLKAD
CG4549_Dmel -LQSELEPHTRQFVVSQMMQCLQDLGQWSQLVELKQQQMTRPEDRELNP---FLQRSNVE
SMG1_Mmus SKSIDSSPEVISYLGNKACECYISIADWAAVQEWQNAVHDLKKNSSSTS---L--NLKAD
smg-1_Cele -----ATNETLKMIIQL---AMVDILNRIRLPQATDYYKVVLFGEESND---S--TITED
SMG1_Ddis ---LESNSISFPFVLEQIIKSYLDISNFTEVEQFLQNYQNQIQQQ-SNS---L--IIYKD
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe -TLSVLGADGVQFIIGRIVESYVSLSDWEALEGWLQELQVLRAKHAGKSYTGALTTAGID
SMG1_Hsap FNYIKSL--------SSFESGKFVECTEQLELLPGENINLLA---------------GGS
CG4549_Dmel VNALERLLAKSEESCSSMD--ALGGVFQQLSLWPSNWDESVSSSGLSERASFSSIHMRQR
SMG1_Mmus FNYIKSL--------SSFESGEFVECTEQLELLPGENINLLA---------------GGS
smg-1_Cele FRSVELL--------TKFEKLN---------NTVNEKRQV--------------------
SMG1_Ddis -TFIKTL--------GSFYRGEMEEAHAFAKRTESQNH-I--------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe MNSIHAL--------SRFDASDMEGTWGYLDLTPQSN-----------------------
SMG1_Hsap KEKIDMKKLLPNMLSPDPRELQKSIEV---QLLRSSVCLATALNPIEQDQKWQSITENVV
CG4549_Dmel TEDIVLHKLLEDRCVPDQAK--NLLDT---QW-RD-----SLLNPSFDQRSCKEL-----
SMG1_Mmus KEKIDMKKLLPNMLSPDPRELQKSIEV---QLLRSSVFLATALNHMEQDQKWQSLTENVV
smg-1_Cele -------------VDWSARERFQFVESAFSQTMRRRVSRVTELLDIQKD-----------
SMG1_Ddis -------------------------------LQREQLGLGLLGNQIMTDELLLSIMVNQK
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ----DMI-----------------------------------------------------
SMG1_Smoe -----------NEITIDPRQALQRSEQ---MLLQAML-------------RKDSEVEDAA
SMG1_Hsap KYLKQTSRIAIGPLRLSTLT-VSQSLPVLSTLQLYCSSALENTV--SNR-LSTEDCLIPL
CG4549_Dmel TLLRHIVQGVSGGQELSLLP-VSSGR--CQNR----------------------------
SMG1_Mmus KYLKQTSRIAIGPLRLSTLT-VSQSLPVLSTLQLYCSSALENTV--SNR-LSTEDCLIPL
smg-1_Cele -----F--SAMGALALSADS-SCKLYSDISSTSLIIANLVNKM-----------------
SMG1_Ddis DLFNNTNIINNNNSGGSSSG-TATATAVTTTTTTTTTTTTTTTT----T-TNTNNDII-G
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ----------------------------------------ENSP--S-------------
SMG1_Smoe REVKLARAMLDGPLLVSSLDDLSDAAPYLT--QLHCIEVVESWKGPSERQEGIQDISLKY
SMG1_Hsap FSEALRSCKQHDVRPWMQALRYT-----------MY----QNQLLEKIK-EQTVPIRSHL
CG4549_Dmel -SKFISSAILMRCLAWTQLLRQH-----------------------------CAP--GSW
SMG1_Mmus FSDALRSCKQHDVRPWMQALRYT-----------MY----QNQLLEKIK-EQTVPIRSHL
smg-1_Cele ----------TGVSQWKNKLTD---------------TEIFDRNEEGND-GDKLAICRKL
SMG1_Ddis FSNNINSMLKLTKNNILKALNYLGLESNVQTFQYLTQLKIMDEIENGVYNSRVVPINNQI
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe FNHPADEV-YQDCHLWLKVLRVY-----------K----------------TVFPHAGVT
SMG1_Hsap M---------------------------ELGLTAAKFARKRGNVSLATRLLAQCSEVQLG
CG4549_Dmel E---------------------------TLCLDAAAAAREEGNLQLAETLLTQFFGQPIG
SMG1_Mmus M---------------------------ELGLTAAKFARKRGNVSLATRLLAQCSEVQLG
smg-1_Cele MHWGRHTKSNRGQS-CAAH------------SEIIRLSRKTSNCELAFFHI---------
SMG1_Ddis GFL-ERLRRVRGHISNTKQRSDILLSNIPLTEKMIKLSRKFENYKFSSKLLDT-------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe S---------------------------TLRRQLIRLARKHGNFRLARRMLKEMDG----
SMG1_Hsap KTTTAQDLVQHFKKLSTQGQVDEKWGPEL---D-IEKTKLLYT--------AGQSTHAME
CG4549_Dmel EIAALFSLEQGVQTD----------NPEMLRGY-SELVKCLHLQQQQSQTHSGDLSSSID
SMG1_Mmus KTTTAQDLVQHFKKLSTQGQVDEKWGPEL---D-IEKTKLLYT--------AGQSTHAME
smg-1_Cele -------------NSAIRGEKLAAWQ-RL---E-VERQRLKLVKTQNLDVRI---REMNE
SMG1_Ddis --------------------ILESHSSSY---Y-LERCKLKYL--------NGKQTEATL
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ----------------------ENWDSKV---AAYENSLLHFS--------EGQHAKAMT
SMG1_Hsap MLSSC----------AISFC--KSVK------AEYAVAKSILTLAKWIQAEWKEISGQLK
CG4549_Dmel VCAAL----------CLNIQ--KSNN------QPAAGADLLLNLADWIAVR---------
SMG1_Mmus MLSSC----------AISFC--KSAK------AEYAVAKSILTLAKWVQAEWKEISGQLR
smg-1_Cele VFGSL----------AEVFTTSCQLK------SDFQMVDGMIKEKMISEGYNEDIAKREE
SMG1_Ddis DLIKYAHRDITIPSSSTTTTTTTTTT------TPPSTSSNTATTTNNI--NIDE------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ELWPL----------VKNFI--AESERALPFEGDVMAATSCLKLGSWLQKRRTE------
SMG1_Hsap QVYRAQHQ--QNFTGLSTLSKNILT-LIELPSVNTMEEEYPR--IESE---STVHIGVGE
CG4549_Dmel -----------TCNGLTTNQ---------SPVLIQLLDQLPECPLTCD---SSQPLAIPQ
SMG1_Mmus QVYRAQQQ--QNLSGLSTLSRNILA-LIELPSANTVGEEHPR--IESE---STVHIGVGE
smg-1_Cele HMSRASIQLADFFQSLPEL-ENVLA-PNLFPTIIW-----------SELQRRSDSLSA-G
SMG1_Ddis ---------------LSTQKFKVYTEIIK------YLNSNPS--IITEL--SSSNYSIPQ
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ----------NDFAGL-----------------------------LSEMDLTSGSGG-MI
SMG1_Hsap PDFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNAS--------QGEGVRLL--
CG4549_Dmel AERMVARLVHSCLQQRPNYAEALIAYGNWCYRWGKKVADSCCVLTQADATAISQALDIPQ
SMG1_Mmus PDFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNAS--------QGEGVRLL--
smg-1_Cele YHGIVGSLFHLASEMCPSLAKAHLKMARWAYEIAKI-KNF-------PAENLS-FYKF--
SMG1_Ddis EQLNPEYYFKKATLTKPENSKLWITYADWILNEKSNISEQN-------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe LEEVAGAAVKAATLHCPSFGKAWFSYASWCYSLARCGFFG--------NETLSKASIFPQ
SMG1_Hsap PREKS--------------EVQNLLPD-------TITEEEKERIYGILGQAVCRPAGIQD
CG4549_Dmel PLESE--------------KLDELLQA-------LSTEQPPANCVEVCP-----DAARAR
SMG1_Mmus PREKS--------------EVQNLLPD-------TITEEEKERIYGILGQAVCRPAGIQD
smg-1_Cele GKDET--------------ENEELLKSLE--------ATSLVNLEKLVR-----A-AI--
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe VLEKELISSSPSLTDEEMMKIQAMIKSLGSELEDAILEMLVKRVVFLL-EAAAREAGFEK
SMG1_Hsap EDITLQITESEDN--EEDDMVDVIWRQLISSCPWLS-ELDESATEGVIKVWRKVVDRIFS
CG4549_Dmel D----------------DEAAKNR----LRRLTFLA-DKTPEALDAILQIWRRAIANTYD
SMG1_Mmus EDITLQITESEDN--EDDDMVDVIWRQLISSCPWLS-ELDENATEGVIKVWRKVVDRIFS
smg-1_Cele ---------SDDL------------RAN----N------ILAPNSHFMHIWKMVRDHRTK
SMG1_Ddis DEESLNGGGSGGNENSSNEMLR-------------------------------LKNTNTN
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe W---------------DGESLSLQLRQEL---QVLKPSSVPGLINELLQVWWGVRKRRIS
SMG1_Hsap LYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDD-MIVMATLRLLRLLVKHAG
CG4549_Dmel YYKDAARSYFQYLSFKSGSGPEKPEG-EGVVSQRERLHVDDSNLVTTTLRLLRLIVKHAS
SMG1_Mmus LYKLSCSAYFTFLKLNAGQVLLDEDDPRLHLSHRAEQSTDD-VIVMATLRLLRLLVKHAG
smg-1_Cele FLSIAVTSYFQFIQNMSGDCDN------------LPYSKKE-ETTLATLRILELLVKHGD
SMG1_Ddis ELKTAVEAYFQFLKYSMLDG----------------NSNGG-LNIRATLKILNILVCSGN
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe LFGYAAHGFLKYMSLSNRTTV------------RSNPLKQD-STLSASLFVLNILQTCGV
SMG1_Hsap ELRQYLEHGLE-TTPTAPWRGIIPQLFSRL-NHPEVYVRQSICNLLCRVAQDSPHLILYP
CG4549_Dmel GLQEVLEQGLH-TTPIAPWKVIIPQLFSRL-NHHEPYVRKSVCDLLCRLAKSRPQLVIFP
SMG1_Mmus ELRQYLEHGLE-TTPTAPWRGIIPQLFSRL-NHPEVYVRQSICNLLCRVAQDSPHLILYP
smg-1_Cele VLIDVINDGLN-KTNVHIWKEILPQLFARL-SHPSEHIRKTLVDLISKICTAAPHAVVFQ
SMG1_Ddis KLVETFERCLNELTSTRPFTIIIPQLFARL-SHPDTFVQKYVVEILNRIGRDNPNKIVYQ
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe ELEDILQQGLS-SIPPSPWKEITPQLFACVSSHPEAKVRKQLEGLLMSLANVYPWAIVYP
SMG1_Hsap AIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGL
CG4549_Dmel AVVGANREQQD---ATAPPATARPTT------------------------E---------
SMG1_Mmus AIVGTISLSSESQASGNKYSSAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGL
smg-1_Cele VVSGAASSSTDG---E--------------------------------------ELEEQQ
SMG1_Ddis TIVGSLNFTNTNN--NNNSSCAAATT------------------------DDGLDIELLQ
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------------------------------------------------------
SMG1_Smoe TLVHFNASE--GQSSE--------------------------------------------
SMG1_Hsap NEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLR
CG4549_Dmel ------DACCYGYLLGELSKQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVS
SMG1_Mmus NEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLR
smg-1_Cele NDDRNRVRACCEKLETNMSQSYPNLVKDVRQFVAELERINLLNEEKWSVVMGTMEHEMEK
SMG1_Ddis KQYPNYLQ--ILNIKENLLKHSELLVKETETLIYQLGKLTTLWDDNWQYFIEQIQGWVYI
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque --ELSSLDRCLAVIVDSLTQKNPIMVKAVRDLVSELCRITLLWDEMWLAALMQRQGEVHR
SMG1_Smoe ---------ELERILNSLSKLHPKVVNDVRLMIAELGSITFLWEEQWLTTLQDLHADVTR
SMG1_Hsap RIQQLEDEVKRVQ---NNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITA-APAETP
CG4549_Dmel RVSALATDFRPDDHEG------KN-------NRFNVWRPQLLADLEALVAVTS-RPPETT
SMG1_Mmus RIQQLEDEVKRVQ---NNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITA-APAETP
smg-1_Cele RLSLIRTENAKTE---SALHLTASVKNDIIVKRTQLLTRQIFDVLDELYQQTVIEPPKSK
SMG1_Ddis NTKQWNDDYQQLKATIKNPTILK----HTLKKKNQELLQPIYEKLKRLTAATVLSVCKTP
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque RLLQIEAETKRTFA-IHNHVLSMERKEAVMRQKYIATMKPLLWVLEYLAAVTA-QPPETQ
SMG1_Smoe RIITLKEEAARIA---ENQTLSPDEKTKINAAKYAAIMAPVSYALERRLTLTS-RPAETP
SMG1_Hsap HEKWFQDNYGDAIENALEKLKTPLN-PAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEE
CG4549_Dmel YERSFRKRFDAPIRLTVDALRHRRY-P----EAWDKLKQLYHILQSNMIRGSGSTLKMQS
SMG1_Mmus HEKWFQDNYGDAIDNALEKLKTPSN-PAKPGSSWIPFKEIMLSLQQRAQKRASYILRLDE
smg-1_Cele NEEEFVTAFAEVLTNAFQESRIS-R-TTSPEKSWIPFKNLIANFVHRNSKKGMQTFETED
SMG1_Ddis HEKWFTKCHFETINKTIRAFEKQNK-PTS------PFDVLH-DLIAEFQQYRLISLSLSS
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque NERQFQAEYGELITMAIQKLQNPSN-YKSSINVWDPFKQLQQMLMHRAQKRMQTPLSLNE
SMG1_Smoe HEVWFQEHFGGQLRAAITTFKTPPGGNITLNDVWKPFDAIAASLSNH-HKRSA--VVLQD
SMG1_Hsap ISPWLAAMTNTEIALPGEV---------------------------------SARDTVTI
CG4549_Dmel ISPVLCGIGRMRISMPGLDA------------------------------HGPDGDQVYI
SMG1_Mmus ISPWLAAMTNTEIALPGEV---------------------------------SARDTVTI
smg-1_Cele ISPYLASLSNSCVPMPGQES-------------------------------VEFDRVVSI
SMG1_Ddis VNPSLALFRPTITQMPGTDLNYFNINHIHHHHHHHNHHGNNNNQHSTSSGNLPIQNQVTI
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ISPHLAAIQSSCISMPGHS---------------------------------QMDEPVLL
SMG1_Smoe VSPRLAALTHSDAPMPGLEF--------------------------------PDADLVTV
SMG1_Hsap HSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATI-
CG4549_Dmel ESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRS
SMG1_Mmus HSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATI-
smg-1_Cele SRVARQVTILPTKTRPKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGK
SMG1_Ddis QLIKPTIYLLPTKTKPKKMAMLGSDGNLYYYLLKGREDLHLDERIMQLLNVVDQLLMND-
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ESFCLDVSVLPTKTKPKKISMIGSDGRRHTYLFKGLEDLHLDERIMQFMAIVNNMFAKA-
SMG1_Smoe ANFNDQITILATKTKPKKVSVTGSDGQVYNYLLKGREDLRLDARIMQLLRASNKMLRAS-
SMG1_Hsap --NRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQ---------
CG4549_Dmel --DAPGNGCYRAHHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQVA---------
SMG1_Mmus --NRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQ---------
smg-1_Cele GKHRQSVAAYQAHHYAVIPLGPRSGLIKWVEGATPMFHIYRKWQMKEKALK---------
SMG1_Ddis --KKPTLKLLRTRNYSVIPLSQSSGLIQWVEGAVPLFSIYKNWYKNDQVYKQQQQQQQQL
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque --HKHQTQLYLARDYAVIPLGARSGLIQWVDNVTPLFGIYKRWQQREALAK---------
SMG1_Smoe --SATRREGLAVKCYSVTPISGRAGLIQWVDNVTSLYSVYKAWQLRQQAAQ---------
SMG1_Hsap -AQKAQDSY-------------------------------Q--TPQNPGIVPRPSELYYS
CG4549_Dmel -GNAGAGA--------------------------------------VANVPRRFTDLFYN
SMG1_Mmus -AQKAQDSY-------------------------------Q--TPQNPSIVPRPSELYYS
smg-1_Cele -QATKKNGE-------------------------------------TVPEIERPSNMYHN
SMG1_Ddis QQQQQQQQQQQQQQPQPQQQPQQQPQQQPQQQPQPQQNSTTTSNIVNKPIIARPVDIFYA
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque -AMQQAGSQ-------------------------------P--TAPLQVQVRKPNELFYA
SMG1_Smoe -LSSNAVSG-------------------------------------APPPLPRPSDMFYG
SMG1_Hsap KIGPALKTVG--LSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRV
CG4549_Dmel KLSPLLAKHN--MQVSDPRRQWPISVLLQVLDELSQETPNDLLARELWCQAGNAAEWRQS
SMG1_Mmus KIGPALKTVG--LSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRV
smg-1_Cele MIRLAFADHKIDSSITSDRSKWPAEILEEVFESLTAKTPTDLISRELWMRANDATTWWSV
SMG1_Ddis KITPLLEKAG--LNFMTPRSEWPKEILIQVLNELMQETPKWILQRELWFSSSSSSELFLK
SMG1_Spur -----------------------------------------------------------L
AqueK047_Aque KIIPLLNEKG--LNEHTPRKEWPLGIQMRVLKELMNETPRDLLTKELWCASSCASEWWAV
SMG1_Smoe KIIPALKEKG--LRKVISRRDWPQDVKRKVLLDLMKETPRQLLYRELWCASDGLKGLNKK
SMG1_Hsap TQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPF
CG4549_Dmel VRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRTLRIPEKVPF
SMG1_Mmus TQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPF
smg-1_Cele TKRYSRSLAVMSMVGSVLGLGDRHLDNLLVDLKWGHVVHIDYNICFDKGKNLRIPETVPF
SMG1_Ddis TQSYSRSLALMSVIGYMIGLGDRHLDNILLDLKTGEIVHIDYNICFEKGAELKIPERVPF
SMG1_Spur TQAFGRSTAVLSMIGYIIGLGDRHLDNVLVNFVTGEVVHIDYNVCFEKGKNLRVPERVPF
AqueK047_Aque TQTYCRSTAVMCMIGYIIGLGDRHLDNLLVEFTTGQVVHVDYNVCFEKGKSLRVPERVPF
SMG1_Smoe IKRFSGSVAVMSVIGHVLGLGDRHLDNILIDFSSGDVVHIDYNICFEKGRRLKVPEIVPF
: : . :::.::* ::*********:*::: *.:**:***:**:** *::** ***
SMG1_Hsap RMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGF
CG4549_Dmel RLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTTNDDAQA
SMG1_Mmus RMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGF
smg-1_Cele RLTRNMRHALGPSEMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDWTSHEHTAT
SMG1_Ddis RMTQIFEYALGLTGVQGTFRETSIQIMHLLRKNKDILLNLLETFIYDPLFDWKHSNKQTN
SMG1_Spur RMTQNVQAALGITGV---------------------------------------------
AqueK047_Aque RMTQNIENALGFTGVEGLFRISCEDILRILRRGRETLLTLLEAFVYDPLIDWTQSEEAAF
SMG1_Smoe RLTQTIQNALGPTGVEGFFRASCEAVLSVLQKNKEVILMLLEAFVWDPLVEWMRGDGHDE
*:*: . *:* : :
SMG1_Hsap AG-----------------AV-YGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWF
CG4549_Dmel LRRSLNAKLQESADGGGAGGLGVGDLKYHKKDKNKGKPLDSDVKRQPFLSKLGMLQKYWS
SMG1_Mmus AG-----------------AV-YGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWF
smg-1_Cele SGVSL----------ALQLAV-YG-----SNWKTKAKERLTD-AMELLNLRMSEVQTLWL
SMG1_Ddis NN-----------------NN--------------------------------------N
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque PL-----------------AM-RT--TTELGVRQTRKEMEWEVAEGMLITKLAESEPHWQ
SMG1_Smoe A-------------------T-I--------GGEERKGMELAVSLSLFASHVQENRVALQ
SMG1_Hsap KNRDEMLVVLPKLDGSLDEYLSLQEQLTDVEKLQGK------LLEEIEFLEGA-------
CG4549_Dmel TNKTELMPQLEEMEQEVGNLQAAQAKQVVAEEELVKLNQRSALIAEIKSLGTA-------
SMG1_Mmus KNRDEMLVVLPKLDSSLDEYLSLQEQLTDVEKLQGK------LLEEIEFLEGA-------
smg-1_Cele ANRDDLLHWMKQVTECL----LIENSM----------------------L-GA-------
SMG1_Ddis NN------------------NNNMNQAAGEQESIEK----------------K-------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque KNRENLCSVLLALEKHLNDIALTSEQMVGYQEKIGK------LDKEISILTEA-------
SMG1_Smoe EHHDQLLRTLPTIPSTLQSWAAGYENFERCSTLAYH------INQKKYAAENAEVAARNL
SMG1_Hsap -------EGVDHPSHTLQHR------YSEHTQLQTQQRAV-QEAIQVKLNEFEQWITHYQ
CG4549_Dmel --------IESHSFNTASLRNAVRRGHSEALALLSTERLPDFGRVQCILRSYGQCLQLYH
SMG1_Mmus -------EGVDHPSHTLQHR------YSEHTQLQTQQRAV-QEAIQVKLNEFEQWITHYQ
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis -------QSSNNSSNPI---------ISTPTKLQQQQKLP-NSPLSISSNN---------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ----V--STPNHPLISMQDR------LSEQSRLSAEQKRL-LSLIKEKYDDSLEWNQKYK
SMG1_Smoe LAEASGSLEKTHVTYEIQAR------EFAQSKARTAEA----------ARETTQWIEQRS
SMG1_Hsap AAFNNLE---------------ATQLASLLQEISTQM----DLGPPSYVPATAFLQNAGQ
CG4549_Dmel L--LDLQ----------------GQLVKLQMESNSE-------NAREFSALTEALQLSGL
SMG1_Mmus AAFNNLE---------------ATQLASLLQEISTQM----DLGPPSYVPATAFLQNAGQ
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque SVFTSLH---------------STDKETTLQKLAAMMREPLDLGSSGHEPAVEFLQKTGQ
SMG1_Smoe RVLDSLRTDTAPELQALGQRTHSTEAVSLLQAIVAS------------GVALTVLPEPTQ
SMG1_Hsap AHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQ--YPKAIFQKHRIEQWKTW
CG4549_Dmel DSMRSQLNE-------LLGRMDMVAQKSSKHLQEYAGVMNF--YPEQ---SHR-------
SMG1_Mmus AHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQ--YPKAIFQKHRIEQWKAW
smg-1_Cele ---------------------------------------------NAIYAQQRVK-----
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque AHTVESCDQLEDELVSLLQRRRTVIHGALEALNQYRVITSQ--FPTRYLEQSRSYLWEHC
SMG1_Smoe VHF----REVDRDISQFTSARHEALLHARATLQAYA-VALQRLLPGNYYTTSYVHSWAKI
SMG1_Hsap MEELICNTTVERCQELYRK----YEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIR
CG4549_Dmel -------------QNLFVR----FHDSFATY--------------IQNGYTADSTTNTNS
SMG1_Mmus MEELICNTTVERCQELYRK----YEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIR
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque LDEIVNSST-EIHHDQFIKIVESFESLLGPSPPT---RLIMATDNKLRKQIQEQGTKF-Q
SMG1_Smoe LQLLSMQVTPEVLGVTKRQ-AID--ITAGGR--GDHDDVICQKHEKLRSHVELLGEEV-Q
SMG1_Hsap QVE--RLKQEAVTVPVC----------------------------EDQLKEIERCI----
CG4549_Dmel PSS--SIICKADVVGVA----------------------------EAMEYSWER-L----
SMG1_Mmus QVE--RLKQEAVTVPVC----------------------------EDQLKEIERCI----
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque KCD--QLEDELVSLLQRRRTVIHGALEALNQYRVITSQFPTRYLEQSRSYLWEHCLDEIV
SMG1_Smoe KLEQGRLQLEESVDPDA----------------------------EKRAK--DKLM----
SMG1_Hsap --------------------------------------KVFLHE--------------NG
CG4549_Dmel --------------------------------------GCQLHE--------------AS
SMG1_Mmus --------------------------------------KVFLHE--------------NG
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque NSSTEIHHDQFINIVESFESLLGPSPPTRLIMATDNKLRKQIQE--------------QG
SMG1_Smoe --------------------------------------GIFLRSLQQGKKDEDDAGLYDF
SMG1_Hsap EEG------------------SL--SLASVIISALCTL------TRRNLMMEGAASSAGE
CG4549_Dmel KLYAANQAQALTLGAP-----TT--ALLSMIVQSGCSQLLLKASLVRTLDRAGGAFAAYE
SMG1_Mmus EEG------------------SL--SLASVIISALCTL------TRRNLMMEGAASSAGE
smg-1_Cele ---------------------------------------------------------AGT
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque TKFQKLTERAQALSSIDMKELDLTVKEAHQNLQKFC-------QGKRWLYMEQTARTARD
SMG1_Smoe EER------------------RL--KVILVLQSAASTI-----------YSEIGNHAANL
SMG1_Hsap QLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQC-----HLVPQD--LDIPNPMEASETV
CG4549_Dmel QVALASHDDG-LLHHQ--------------LLFI-----HLVRTM--LQGVLVMTKEEDQ
SMG1_Mmus QLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQC-----HLVPQD--LDIPNPVEASEAV
smg-1_Cele ELREAVTRHH--------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque RLSDLTSREGDWFMDELCTMGGNVFQMSSTLETCLSYLGHDIQSD--TLVRSCLD---SV
SMG1_Smoe QGVGMEESIRRWCFPELEGLVERAVLVSDVLNELQQ-----FSGKATGYRANPWDSNSSF
SMG1_Hsap HLA-NG---VYTSLQELNSNFRQIIFPEALRCLMKGEYTLESML---HELDGLIEQTTDG
CG4549_Dmel HLA-Q----------------------------------LESLL---SALSHLKKMFEYD
SMG1_Mmus HLA-NG---VYTSLQELNSNFRQIIFPEALRCLMKGECTLESML---HELDSLIEQTTDG
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque AAV-HS---VYSSMLDLVNKFYSLVMPEVSKSIISDDPSFVQML---DDVADIKLTMFPE
SMG1_Smoe TAELKGFTDCLAGIDHLVKQMIGVVLPEAVKAALSQDPAVMDAFASLSQIRGAIDTTLEK
SMG1_Hsap VP-------------------LQTLVESLQAYLRNAAMGL-------EEETHAHYIDVAR
CG4549_Dmel LP--------------------------------------------------AN---LYR
SMG1_Mmus VP-------------------LQTLVESLQAYLRNTAMGL-------EEETHAHYIDVAR
smg-1_Cele ----A-------------------LAKELRPLIR--VIGK-------EREEFADYLKFYK
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque LP-------------------LPDALRKLIEHLRQCALKNVP----ADLTTTAAVEDLKN
SMG1_Smoe VAEIEMQKSALLELERTYPDRLEELVKR-KTFLEEAAAGGKDDLSWEEAEELASQEDLCR
SMG1_Hsap LLHAQYGELIQPRNGSV----------------------------DETPKMSAGQMLLVA
CG4549_Dmel L------LLLQPNLGKL----------------------------SALCHLSASSLAQLF
SMG1_Mmus MLHAQYGELIQPRNGSV----------------------------DETPKMSAGQMLLVA
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque KLST---IMFSSECEEG----------------------------HDTPSLTQAQVILNG
SMG1_Smoe EQLETLQKAWSQRSAQASAVLRMEGLVRSALASADQRFEALVALDRDDLHLMRGKVLLAA
SMG1_Hsap FDGMFAQVETAFSLL----VEK---LNKMEIPIAWRKIDIIREARS---TQVNFFDDDNH
CG4549_Dmel LEATMEN------------------GHKP------------------------------P
SMG1_Mmus FDGMFAQVETAFGLL----VEK---LNKMEIPVAWRKIDIIREARS---TQVNFFDDDNH
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis -------------------------------------------TNS---TNNNNNNNNNN
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque LNSLFEAVESQTLNM----LDQ---VEEITVPDEWRNTDLVKQTKEVMCTTAGLF-----
SMG1_Smoe FAKLFSGLESLDAALRRVPVAKTMQVESPGLEYIWRASNVLQ------------------
SMG1_Hsap RQVLEEIFFLKRLQTIKEFFRLCGTFSKTLSG----SSSLEDQNTVNGPVQIVNVKTLFR
CG4549_Dmel DQFPVERRFLLTLQPVYDQFLLASTSLDSLVS--SMQSMLEDVHDVQT-QQIMELG-LM-
SMG1_Mmus RQVLEEIFFLKRLQTIKEFFRLCGTFSKTLSG----SSSLEDQNTVNGPVQIVNVKTLFR
smg-1_Cele ----------------------QALFDPLLKG----HSALRN------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque --LKEDLLFVRKVSSIVDFCSECKNLMKAFKLELTSDGGGEYLSLVSP-PGTPSKRSSSS
SMG1_Smoe ----KKTFFVWKVYVM----------------------------------------DILL
SMG1_Hsap NSCFSE----------------------DQMAKPIKAFTADFVRQLLIGLPNQALGLTL-
CG4549_Dmel RSCHTELNDECFFGLVSEALESSRTCDVREMARPMLGFIHRLQVEKLAGL----LPILT-
SMG1_Mmus NSCFSE----------------------DQMAKPIKAFTADFVRQLLIGLPNQALGLTL-
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque VPVPTD----------------------QQLSHPIRRYISETLICHVLGQPSYALTCLLV
SMG1_Smoe DSCVRD--------------------ASNDLSLSLDQVISQHKRRLEAQL-QGVLDLYL-
SMG1_Hsap CSFISALGVDIIAQ-VEAKDFGAESKVSVD-DLCKKAVEHNIQIGKFSQLVMNRATVLAS
CG4549_Dmel RNFYTAVGPQCLPT-ASCGD-----PAQAD-HLCESL-----------------------
SMG1_Mmus CSFISALGVDIIAQ-VEAKDFGAESKVSVD-DLCKKAVEHNIQVGKFSQLVMNRATVLAS
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque CTVTQYLEA----P-I---QFGK--PTTIE-EMCKVANEHCQSML--PLGVVQHARTLFS
SMG1_Smoe RERVSPAFLDIILKEATISSFADNSDSSREGEAAKKAVKLLRE--------------YCD
SMG1_Hsap SYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQ--------------WQHEDLL--
CG4549_Dmel ---------------FISLQSDGALLQ-QQAEIALLSQQVDLHTLAASAQYWAYSEALGS
SMG1_Mmus SYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQ--------------WQHEDLL--
smg-1_Cele ---------------ELDIDTCVYNFNI--------------------------------
SMG1_Ddis -----------------------------------------------------NNNNN--
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque HHDVAWREWDKARRLTTNLENCKQSIQRLKNITMRFQ--------------WLHEESL--
SMG1_Smoe VHETVRAAKSAAFALKIQADEAKQSLQNAQIEIAQME--------------WLHETVL--
SMG1_Hsap --------INRPQAMSVTPP------------PRSAILTSMKKKLHTLSQIETSIATVQE
CG4549_Dmel QLRCGPHIVSRPKLTAA----------------IGECWLELDQKLTALQQLQAGL-----
SMG1_Mmus --------ISRPQAMSVTP-------------PRSAILTSMKKKLHALSQIETSIGTVQE
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis --------NNNNNNNK--------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque --------IVPDAVHTWVVQ------------QRSALLTVIKKVLS--EQLATSIGNVIE
SMG1_Smoe --------LPRVQFVAMPSGPYPEKSTSIRWWSRKQILDNIRNSIAAISRATEGLQKAER
SMG1_Hsap KLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNIIH
CG4549_Dmel -----ESQLSQ-------------------------------LQTQRSNWNRNHIDNLLR
SMG1_Mmus KLAALEASIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRANQVTFLCSNIIH
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque KIHSQQFRISQRLQWAAGANSSLNKVIDEFQRACNHHKTMLEREESIFIEMEEMAKAIIH
SMG1_Smoe ASVSAEEQLERTMAWASNR----AGTSQEFRERLQRRQQLLWTGQEHATSTVRLCVTVLE
SMG1_Hsap FESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIG-
CG4549_Dmel MEQCNK-----------------------------------------QR-----------
SMG1_Mmus FESLRTRTAEALSLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTTLEHPIG-
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque LESSHTRIPAQTSSDRETIQILQRCSDVTVKLKLCGE-----ELTQLSDIMPHLQLPSDG
SMG1_Smoe FEASREGYLESSSSSSSS--------DGKSWQQSYQSLILRLEAAYIAF-------TSC-
SMG1_Hsap ---SSEWLLSAHKQLTQDM-------STQRAIQTEKEQQIETVCETIQ---NLVDNIKTV
CG4549_Dmel --------TMSHVALLQKM-------TDGAGAVARLEQNAIVVGEEGQ---ALVDHLEQW
SMG1_Mmus ---SSEWLLSAHKQLTQDM-------STQRAVQTEKEQQIETVCETIQ---SLVDSVKTV
smg-1_Cele ------------------------------------------VMQNIDNVF---------
SMG1_Ddis ---------------DQD---------S--------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque SPLNKEWI---QKRLDEAT-------SERTKLQGDKKFSNNKVVKNKENVLSELEKLRSL
SMG1_Smoe ---DMEWK-AAQKALEAASANLSGVLRERQLVSSESESSGDHCAAE--------------
SMG1_Hsap LTGHNRQLG----------------------------DVKHLLKAMA--KDEEAALADGE
CG4549_Dmel LAAHGQWQASSSRISAVEQSMVELLDPEGAIDHYWLENVQGLLEEQTCKVHREIAAIEGE
SMG1_Mmus LTGHNRQLG----------------------------DVKHLLKAMA--KDEEAALADAE
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque NRQHRKLLV----------------------------EVWQQLTSLA--KLEDPPAA-GQ
SMG1_Smoe ------------------------------------------------------------
SMG1_Hsap DVP----YENSVRQFLGEYKSWQDNIQTV----LFTLVQ--AMGQVRSQEHVEMLQEITP
CG4549_Dmel QQS----KHRFICTLLKETLRLLENMPRFHVQSLCSEAQ--AQGQGKM--EYANVQLLSD
SMG1_Mmus DIP----YESSVRQFLAEYKSWQDNIQTV----LFTLVQ--AMGQVRSQEHVEMLQEITP
smg-1_Cele ------------------------------------------------------------
SMG1_Ddis ------------------------------------------------------------
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque LQPGPRAFINHQNRFGEETKSFIQSTQDL----IASDMSLTSKPSWTSKARAEEFRQLGT
SMG1_Smoe ------------------------------------------------------LQSIFL
SMG1_Hsap TLKELKTQSQSIYNNLVSFASPLVTDATNEC-------SSPTSSAT-YQPSFAAAVRSN-
CG4549_Dmel HLREGQGLMQSLYMRLQELRKDICSDRR-----------------V-LQPSMLQNWRHQL
SMG1_Mmus TLKELKTQSQSIYNNLVSFASPLVTDAANEC-------SSPTSSAT-YQPSFAAAVRSN-
smg-1_Cele -------------GAL--------------------------------------------
SMG1_Ddis -----------------------------------------DSSQS-QEDEDNNVVEGE-
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque MAVNLRGLAEWILGQLLSFTEQLFINPYSSKLKWHEPLQLESSSISLKNRSSSLSVASQ-
SMG1_Smoe QLRQLTLEAAG------------------------------------AVNAFCKVVRSH-
SMG1_Hsap ------------TGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGTGKSVACSPKKAV
CG4549_Dmel EMILTLAKQEVNEFFKGLEDFMQHA--------GETDSYEIFTHAKGS------------
SMG1_Mmus ------------TGQKTQPDVMSQNAKKLIQKNLATSADTPPSTIPGTGKSIACSPKKAV
smg-1_Cele ----VNL------------------------------SFTPIETITSRTSQQEFKPPPGL
SMG1_Ddis ------------GGEGGEGD---------------------------------IDELNLV
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque ------------SGQQ---DSEQQS-------------------------RIYRSSQGIV
SMG1_Smoe ------------SALTSEGAVMLDEARADGVSDVHSL-----------------------
SMG1_Hsap RDPKTGKAVQERNSYAVSVWKRVKA------------------KLEGR---DVDPNRRMS
CG4549_Dmel ----GNVHEQKRNAYGVSVWKKIRM------------------KLEGR---DPDSNQRST
SMG1_Mmus RDPKTGKAVQERNSYAVSVWKRVKA------------------KLEGR---DVDPNRRMS
smg-1_Cele ENVWVVKQDQQENSQAREVVRRVER------------------RLNGWLDGSAGPDRKLS
SMG1_Ddis QDSSNGK-DAFKSIQGLTVVNQVRL------------------KLEGT-------EKKLS
SMG1_Spur ------------------------------------------------------------
AqueK047_Aque RDLRTGKALQEQNSYAVSVWRRVKG------------------KLDGR---DPDPACRMT
SMG1_Smoe ----AKEAITERQSL-ISDLKKVHAAVAPLELLLSSTANAMSADLDVK---AVIKSGQSP
SMG1_Hsap VAEQVDYVIKEATN---------L------------------DNLAQLYEGWTAWV
CG4549_Dmel VAEQVDYVIREACN---------P------------------ENLAVLYEGWTPWV
SMG1_Mmus VAEQVDYVIKEATN---------L------------------DNLAQLYEGWTAWV
smg-1_Cele PREEADILIAEATS---------T------------------PNLSQMYEGWTAWV
SMG1_Ddis IPDQIDLIIRESMN---------V------------------ENLSSTYEGWSPWV
SMG1_Spur -------------------------------------------------------E
AqueK047_Aque VAEQVKFVIDEATS---------P------------------ENLCQLYEGWTPWV
SMG1_Smoe TLQSLDLKIKESLADLPLHVSSVLDAAQKLHSALTSLGRTASVDAGTLNKASPNVS