E02D9.1_Cele LQRGKYVGNGMHATVRMALHEKTQKWYVIKTILS-------QNTDKTEY---EKEILAYE
F35C8.1_Cele LYGGERIGNGEGQSAVYRL-IYNGKLIARKDVAVRLPKGVDQDSTNKLMAKKLREVNVIN
F35C8.2_Cele LHGGVRIGSGEGQSAVYRL-IYNGMVIARKDVAVRLPQGGDEDSTNKLMAKRLREVNVIN
MKK1_Scer IETLGILGEGAGGSVSKCKLKNGSKIFALKVINTL-------NTDPEYQKQIFRELQFNR
MKK2_Scer ITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTM-------NTDPEYQKQIFRELQFNK
PBS2_Scer LEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRL--------ELDEAKFRQILMELEVLH
STE7_Scer LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVE-------QNNSTIINQLVRELSIVK
1557_Tthe ------------------------------------------------------------
1909_Tthe LRRVKVLGHGSSGLVELAVHDATGIVIGIKSIPLL--------MNSSFRKQLDQELKTLI
26687_Tthe FEVVSELGKGAFGKVYKVCHKKDGKIYAMKEIIMV--------DDIELRQKILMEVKTLF
Mek1_Ddis LKIIRVLGRGAGGVVKLAYHETSGTYIALKVITLD--------IQENIRKQIILELKTLH
12278_Tthe FETISELGRGASGRVFKVKHKETGKFYAKKEIRIN--------DDEMFQKQLIWEIKTLF
CC1G_01983_Ccin FEEISRLGEGAGGAVHKVKDKRNGMIMARKTITT--------R--EAPMKQLLRELTIMS
CC1G_14241_Ccin QLDDEELGRGNYGTVKKVLHKPTNVAMAMKEIRD--------SI-QANSPAIIMELDVLH
E02D9.1_Cele ECSQSDYVVGYHGCEVSS----IKKELVLEYMDKGD-----------F------------
F35C8.1_Cele GCAPCPFIVHFFGYYVHKYRDCVKIHIFMEEMALSA-SVLKT---EAL------------
F35C8.2_Cele GCAPCPFIVHFFGYYVHKYKDCVKIHIFMEEMALSA-SVLKK---EVL------------
MKK1_Scer SFQ-SEYIVRYYGMFTDDE--NSSIYIAMEYMGGRSLDAIYK---NLL------------
MKK2_Scer SFK-SDYIVQYYGMFTDEQ--SSSIYIAMEYMGGKSLEATYK---NLL------------
PBS2_Scer KCN-SPYIVDFYGAFFIE----GAVYMCMEYMDGGSLDKIYD---ESS------------
STE7_Scer NVKPHENIITFYGAYYNQHI-NNEIIILMEYSDCGSLDKILSVYKRFV------------
1557_Tthe ----HPNLITCFGAYYEE----GTIKIILELMDFGSIRNLID---M--------------
1909_Tthe QCE-SDSIVKCYGAYIQK----CMINITLEYMDLGTVHDLVK---K--------------
26687_Tthe ICQ-SPYIVTYYGAFYTE----GKLHIILEYMDVGTLDSLLK---K--------------
Mek1_Ddis KTS-YPYIVSFYDAFYTE----GSIFIALEFMELGSLSDIMK---K--------------
12278_Tthe SCN-SPHIVQYYCAFYTE----CMLHLILEYMDMGTLDTILK---K--------------
CC1G_01983_Ccin STK-HVNIITFYGAYMSPS--SSEIKIIMEYCEGGSLESVGK---RIR------------
CC1G_14241_Ccin RAV-APEIVEFYGAFFIE----SCVYYCMEYMDAGSLDKLIQ---SNSQPPQPQIPKPPS
:: . :*
E02D9.1_Cele --------------------------------------------------RP------FG
F35C8.1_Cele --------------------------------------------------KQ------GG
F35C8.2_Cele --------------------------------------------------KR------GG
MKK1_Scer --------------------------------------------------ER------GG
MKK2_Scer --------------------------------------------------KR------GG
PBS2_Scer ---------------------------------------------------E------IG
STE7_Scer --------------------------------------------------QRGTVSSKKT
1557_Tthe ----------------------------------------------------------LK
1909_Tthe ----------------------------------------------------------VG
26687_Tthe ---------------------------------------------------A------GG
Mek1_Ddis ----------------------------------------------------------TS
12278_Tthe ----------------------------------------------------------TK
CC1G_01983_Ccin --------------------------------------------------ER------GA
CC1G_14241_Ccin SDPIQTDASSPEYSFAMPFVEEDLDLTKDENFEPYNRAFNRTCPPPIPSTYS------GG
E02D9.1_Cele ILPFSVHQ------------SVALSLIRAIRHVWNSGPGYIHRDIKPENILVN-SQGYVK
F35C8.1_Cele AIPEFVIG------------RIVCSVIHAMWFLKD-RLQIIHRDIKPGNILID-YDGRVK
F35C8.2_Cele IVPEFVIG------------RIACSVIHAMWFLKE-KMQIIHRDIKPGNILID-YDGRVK
MKK1_Scer RISEKVLG------------KIAEAVLRGLSYLHE-K-KVIHRDIKPQNILLN-ENGQVK
MKK2_Scer RISERVIG------------KIAESVLRGLSYLHE-R-KVIHRDIKPQNILLN-EKGEIK
PBS2_Scer GIDEPQLA------------FIANAVIHGLKELKE-QHNIIHRDVKPTNILCSANQGTVK
STE7_Scer WFNELTIS------------KIAYGVLNGLDHLYR-QYKIIHRDIKPSNVLIN-SKGQIK
1557_Tthe EINYCYLSKILCNQKYQYHFFILKQLLKGLEFLHK-ERHQVHRDIKPENILIN-KRGNVK
1909_Tthe PLPEIIVA------------IMAIQVLKGLDYIHN-KAKVIHRDIKPSNLLVN-SKGQVK
26687_Tthe KVSEVVLK------------YLTYQILKGLKYLHK-DLHIIHRDIKPGNILVN-SKGEIK
Mek1_Ddis TIPEPVLG------------KIAFQVLQGLVYLHR-KLHLIHRDIKPSNILVN-NKGEAK
12278_Tthe QVSEPILI------------YTTYQIIKGIHYLHK-DLKIIHRDLKPGNILVN-SEGEIK
CC1G_01983_Ccin IVGEKIAG------------RLAEGVLQGLSYLHS-K-KTIHRDIKPSNILLS-KEGVVK
CC1G_14241_Ccin PIPEAILG------------RIAASMVRGLKFLKD-ELNIIHRDVKPTNVLVN-CKGQVK
. ::..: : :***:** *:* . * *
E02D9.1_Cele ICDFGAAKRIDNTYRIASSAAGTQMYQAPEQQ-----MGQ--------------------
F35C8.1_Cele ICDFGICGILENS--IAVSDTGCQQYTAPEILVKGVSNSP--------------------
F35C8.2_Cele ICDFGISGILQDS--IAVSATGCQQYTAPEINELAMVHSP--------------------
MKK1_Scer LCDFGVSGEAVNSL--ATTFTGTSFYMAPERI-----QGQ--------------------
MKK2_Scer LCDFGVSGEAVNSL--AMTFTGTSFYMAPERI-----QGQ--------------------
PBS2_Scer LCDFGVSGNLVASL--AKTNIGCQSYMAPERI-----KSLN-------------------
STE7_Scer LCDFGVSKKLINSI--ADTFVGTSTYMSPERI-----QGN--------------------
1557_Tthe LTDFGISKQLEKTQQLCMTYVGTTLYMSPERL-----IGN--------------------
1909_Tthe IADFGVSANLESAVE-VKNWVGTVTYMSPERF-----RGQ--------------------
26687_Tthe ISDLGICGAINATLDERQTFVGTSIYMSPERL-----SGE--------------------
Mek1_Ddis IADFGVSGQLQHTLSKAVTWVGTVTYMSPERI-----SGR--------------------
12278_Tthe ISDLGICGKVNGTMDQKNTFVGTTIYMSPERL-----NGD--------------------
CC1G_01983_Ccin LCDFGVSGELILSQ--AGTFTGTSFYMAPERI-----QGK--------------------
CC1G_14241_Ccin LCDFGVSGQLDKSM--AKTNIGCQSYMAPERI-----RGESRVVGAVPASEGGTGTAAAA
: *:* . : . * * :** .
E02D9.1_Cele ----------------DYSEKVDIWCFGLTLWEFAIGPNLEEY-----------------
F35C8.1_Cele ----------------GYSIKSDIWSLGITIFELATLRYPYPVG----------------
F35C8.2_Cele ----------------GYSIKSDIWSLGITIFELAT------------------------
MKK1_Scer ----------------PYSVTSDVWSLGLTILEVANGKFPCSSEKMA-------------
MKK2_Scer ----------------PYSVTCDVWSLGLTLLEVAGGRFPFESDKIT-------------
PBS2_Scer ------------PDRATYTVQSDIWSLGLSILEMALGRYPYPPETY--------------
STE7_Scer ----------------VYSIKGDVWSLGLMIIELVTGEFPLGGHNDT-------------
1557_Tthe ----------------QYGLRSDIWSVGLVIIELATGLYPYDVK----------------
1909_Tthe ----------------AYTANTDIWSLGLTICECALGTYPYFDSNQYEK-----------
26687_Tthe ----------------SYSVKTDIWSFGLLLLEFSESKNPLQLNE---------------
Mek1_Ddis ----------------SYSFDSEIWSLGLTILECAIGKFPYGSNLPHQQQQPLQQQQQQQ
12278_Tthe ----------------SYTMKTDIWSVGLLLIEFSEGKHPIQAS----------------
CC1G_01983_Ccin ----------------EYTIRSDVWSTGISLLELVQNRFPFPPD----------------
CC1G_14241_Ccin QGGVPGTAALADELYGAYTVSSDVWSLGLSIIELGLGRYPYPPETY--------------
* ::*. *: : *
E02D9.1_Cele ------------------------------------------------------------
F35C8.1_Cele ------------------------------------------------------------
F35C8.2_Cele ------------------------------------------------------------
MKK1_Scer ------------------------------------------------------------
MKK2_Scer ------------------------------------------------------------
PBS2_Scer ------------------------------------------------------------
STE7_Scer ------------------------------------------------------------
1557_Tthe ------------------------------------------------------------
1909_Tthe ------------------------------------------------------------
26687_Tthe ------------------------------------------------------------
Mek1_Ddis QQQQQPLQQQQQQQQQQQQPLQLQLQNLDINNSNNNIRNSNNNNNNNNNNNNNNNNNNNN
12278_Tthe ------------------------------------------------------------
CC1G_01983_Ccin ------------------------------------------------------------
CC1G_14241_Ccin ------------------------------------------------------------
E02D9.1_Cele --------------------LNGLSSYEEITVE-----PI--------------------
F35C8.1_Cele --------------------FSEFTLLSAIVTTPAPYLER--------------------
F35C8.2_Cele ------------------------------------------------------------
MKK1_Scer ------------------ANIAPFELLMWILTFT-PELKDEPE-----------------
MKK2_Scer ------------------QNVAPIELLTMILTFS-PQLKDEPE-----------------
PBS2_Scer --------------------DNIFSQLSAIVDGPPPRLPS--------------------
STE7_Scer -------------------PDGILDLLQRIVNEPSPRLPKD-------------------
1557_Tthe -------------------NKSIVQFVSNILQSKEPTLPDN-------------------
1909_Tthe -----------------KENLSFWELLEYFNMKPAPRLPE--------------------
26687_Tthe -------------------NASFFEILAKVMNFSIPELNS--------------------
Mek1_Ddis NVLDISNGGLVDSGSSVPEGMGFWVLLDCIVKEEVPILPS--------------------
12278_Tthe --------------------NNFFEVLNNIIDFKIPPLKN--------------------
CC1G_01983_Ccin --------------------LPPIELMMYITNSEPPRLEDEP------------------
CC1G_14241_Ccin --------------------SNVFAQLTAIVHGPPPCLPSGPPPPLSPDDDSSFEEPVLP
E02D9.1_Cele ------------------DGFPESLAVLISNCLYS-------HTNFV----------KMF
F35C8.1_Cele ------------------VTFSN-------------------------------------
F35C8.2_Cele ------------------------------------------------------------
MKK1_Scer ----------------SNIIWSPSFKSFIDYCLKKDSRERPSPRQMI----------NHP
MKK2_Scer ----------------LDISWSKTFRSFIDYCLKKDARERPSPRQML----------KHP
PBS2_Scer ------------------DKFSSDAQDFVSLCLQKIPERRPTYAALT----------EHP
STE7_Scer ------------------RIYSKEMTDFVNRCCIKNERERSSIHELL----------HHD
1557_Tthe ------------------GKYSAALMDFVKKCVAKEQKDRLDISDLL----------KHE
1909_Tthe -------------------NYSEEMKDFVAKCFKKSPLDRPHSHDLL----------NHE
26687_Tthe -------------------IKSKEFIQFVEQCTKINPKERADVVQLL----------ELP
Mek1_Ddis -------------------TFSKEFRSFISECLQKEPTERPTASNLL----------NHE
12278_Tthe -------------------INSPEFTNFIEICLKSDQNERADITQLLVNTTSFSSFNEHP
CC1G_01983_Ccin -----------------GVNWSEEMKDFIKQALTVDPVDRPTPKDML----------EHP
CC1G_14241_Ccin PTLDDQDPLISPTTGRQRPGYSPFARDWVNKCMRKDAKERATYKELL----------EHP
E02D9.1_Cele FL
F35C8.1_Cele NY
F35C8.2_Cele LT
MKK1_Scer WI
MKK2_Scer WI
PBS2_Scer WL
STE7_Scer LI
1557_Tthe WI
1909_Tthe MV
26687_Tthe FV
Mek1_Ddis FV
12278_Tthe FL
CC1G_01983_Ccin WI
CC1G_14241_Ccin WL