Spk376_Spur     M-----------------------------------------------------------
Spk383_Spur     MEDKPNIPGLTQETEQQSIQRRA----NRPRRQPAGVPDDQPTVEMRAALAEGASDAIAT
Spk379_Spur     MGIFI----LHSS-----------------------------------------------
Spk380_Spur     MDPQDEIA-----LPENA-LQHIRST-----WKEMG------------------------
Spk370_Spur     MKKIVNLE-----VEAKSVLERIEIF-----AIDVGVAEDLP------------------
Spk369_Spur     MDENPDLG-----LSSPKPQRRAQQMTNRRRRPQASGAHDGH------------------
Spk400_Spur     MKNIVNLE-----VEAKSILERIKIF-----AIDVGVVEDLT------------------
Spk401_Spur     M-----------------------------------------------------------
                *

Spk376_Spur     ------------------------------------------------------------
Spk383_Spur     ATNQLVPVTVLDNGDDGIIIEAGESTRQSLEQQLAVADAQLK-DFKALQEAAKSLTGSTE
Spk379_Spur     ------------------------------------------------------------
Spk380_Spur     -----------------SRCEKVESSWKEKVIQLTSDLTAARTYIQTVEAELLHV---Q-
Spk370_Spur     -----------------------EIRTVKLVPKIHTKSAELRREIEYLREERVLY---TE
Spk369_Spur     -------------------------------------TAEVLAAVEQ----TNRA---TD
Spk400_Spur     -----------------------EIRTVKLVSQINTKTAELRREIEYLREERVLF---RE
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     ------------------------------------------------------------
Spk383_Spur     DTPAGALAKGLVSAREEKQAD-------------VR--------MVETEIRQIQREKDQT
Spk379_Spur     ------------------------------------------------------------
Spk380_Spur     -ES-------------QTNCW-------------PN--------IIKR-----RWFPRR-
Spk370_Spur     DSS-------------KIQAQ-------------TN--------LIVEKESQLRRYTER-
Spk369_Spur     DGG-------------ALVASGQAAGQLSPGSLAPGLLAPETDDRSVNQERVIRMTTAR-
Spk400_Spur     DSS-------------KIQAQ-------------TN--------LIVEKESQLRRHVER-
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     ------------------------------------------------------------
Spk383_Spur     QTTLKLFVIAASVYSSLQKDKAIL--------------------ERQIIKL---------
Spk379_Spur     -------FLAASVYSSLQEDKAIL--------------------EKQIFKL---------
Spk380_Spur     ---------KKSKVVPNQGER-----SGKSEQ--TKELDEKSNLTNQL---KNLSNAG-G
Spk370_Spur     ---------MNSRINSLEKDKAIL--------------------ESQIGKL---------
Spk369_Spur     ---------PDVCLEAFQKNMEAGESSGQADEDLLKQLES---AQAQLKGYEGLAHAAAA
Spk400_Spur     ---------MNSRINSLEKDKAIL--------------------ESQIGKL---------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     ------------------------------------------------------------
Spk383_Spur     ---KDGSEAANRMVKEMSQKNKEMANGRKEAEREKKQAEGEKAKAEREKVKAEKEKVKAE
Spk379_Spur     ---KDGSEAANMMVKEMAQKNKEMANERKEAEREKNQAE-------KEKVKAEKEKVKAE
Spk380_Spur     TSPKEVDR----------------TED---------------------------------
Spk370_Spur     ---MECDEAAKRLTQKLMEQNRTLEEDNQ-------------------------------
Spk369_Spur     ITGSTVDTPAETLAKSLMDAWGEQRFNQD-------------------------------
Spk400_Spur     ---MECDKAAKRLTEKLVEQNKTLEEENQ-------------------------------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     ------------------------------------------------------------
Spk383_Spur     KLMKEMEKKMKLEERKRGYVERLNQVLLEKLCHMQQDIAQKTDDIAQKTDDIALNTQIIA
Spk379_Spur     KLMEEMEKKMKLEESKREYVERLNQVLLEKLCHMEQDIAQKTDDI-------AHNTQMIA
Spk380_Spur     -----------------------FQCTLTKVRGLEYDCQRLQEKN---------------
Spk370_Spur     -------------------------DMEEKVGLLEYETDRQTDT----------------
Spk369_Spur     -------------------------QMESRIEHIKTEKEQVQDEL---------------
Spk400_Spur     -------------------------DMEKKVGLLEYETDGQTDKI---------------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     ------------------------------REAKTNVDRVVIACLHFVSPQELAIQDLMS
Spk383_Spur     LKNEQI---IQLKGI--NDKLQEITDLRLMREAKTNVDRVVIACLNFVSPQELAIQDLMS
Spk379_Spur     LKNEQISHLNKLKEM--NDNLQEITDFRLMQEAKTNVDRVVIACLNFVSPQELAIQDLMS
Spk380_Spur     ---------QGLRDLIENLGAHLGKTQGPILDVRTIADVAVIATLGSNPCTELSMHDVIT
Spk370_Spur     ------------------MRYNEMYPNSAINDVQSQSDHAVIASLTTLRCKKLDLSTLRE
Spk369_Spur     -----------------KMRYNEMYPNSAINDVQSQSDHAVIASLTTLRCKKLDLSTLRE
Spk400_Spur     ---------KRLYDLMERMRYNEMYPNSAINDVQSQSDHAVIASLTTLRCKKLDLSTLRE
Spk401_Spur     -------------------RYNEMYPNSAINDVHSQSDHAVIASLTTLRCKKLDHSTLRE
                                               :.::  * .*** *      :*    :

Spk376_Spur     FNHSSA-SDQTILETVGKGSYGEVMLGRLNGEKDPVVIKRALVKQNLTAELEESDRKQCN
Spk383_Spur     FNHSSA-SGQTILEFVGKGGYGEVMLGRLNGEKDPVAIKRALVKQNLTAELEESDRKRRN
Spk379_Spur     FNHSSA-SDQNILETVGKGSYGEVMLGRLNGEKDPVVIKRALVKQNLTAELEESDGKQRN
Spk380_Spur     FHATSILDNDFKFKEIGRGAFGRVLLARLTASSDTVAIKEPLIPPYFSPPKIEAERRANF
Spk370_Spur     -SKSGD-SSKLELDMIGNGSFGIVLLGHLDGLSKPVAIKRPYVPAHQKGEAAENEWKANQ
Spk369_Spur     -SKSDD-SSKLELDMIGNGSFGIVLLGHLDGLSKPVAIKRPYVPAHLKGEAAENEWKANQ
Spk400_Spur     -SKSDD-SSKLELDMIGNGSFGIVLLGHLDGLSKPVAIKRPYVPAHLKGEAAENEWKANQ
Spk401_Spur     -SKSDD-SSKLELDMIGNGSFGIVLLGHLDGLSKPVAIKRPYVPAHLKGEAAENEWKANQ
                   :.  ...  :. :*.*.:* *:*.:* . ...*.**.. :    .    * : :

Spk376_Spur     IRCEKEARAGLMMS-TSPYFPRFLGTVMTDGDHCLVTEFIGDKIQGKTYMLMDAICPRKG
Spk383_Spur     VRYEKEARAGLVMS-TSPYFPRFLGTVMINGDHCLVTEFIGDKIQGKSYVLYDAIIPRKG
Spk379_Spur     IRCEKEARVGLMMS-TSPYFPRFLGTVMVNGGLCLVTEFIGDKIQGKSYELYDAICPSEG
Spk380_Spur     GQFTKEAVVSQFLS-RSNHFPKLYGTLVLDENMCIVQEFIGDKKTGKVFPLLNIM---E-
Spk370_Spur     GRTRKESLVLELLK-GCPYFAQMVGTITIGRELCVVTEFVGSGQTGRPYRLHDAL---QV
Spk369_Spur     GRTRKESLVLELLK-GCPYFAQMVGTITIGRELCVVTEFVGSGQTGRPYRLHDAL---QE
Spk400_Spur     GRTRKESLCLQLLKGXCPYFAQMVGTITIGRELCXCNRVRGSGQTGRPYRLHDAL---QE
Spk401_Spur     GRTRKESLVLELLK-GCPYFAQMVSAITMGRELCVVTEFVGSGQTGRPYRLHDAL---QV
                 :  **:    .:.  . :*.:: .::  .   *   .. *.   *: : * : :   :

Spk376_Spur     CDPVPDVQKWNLVAIGEDIIRGVIALHGLSLLHNDIKDDNVLLEFRKNRWVAVIIDLGMV
Spk383_Spur     CDPEPDVQKWNLVAIGEDIIRGVMALHGRSLLHNDIKDDNVLLEYRKNRWVAVIIDLGMV
Spk379_Spur     CDPVPDVQKWNLVAIGEDIIRGVMALHGRSLLHNDIKDDNVLLEFRKNRWVAVIIDLGMV
Spk380_Spur     SNPSPFLSPPSLLDIADDVLEGIHFMHSNGLLHNDIKADNVLLELRNERWYGCIIDLGLV
Spk370_Spur     IDPILYPSIWNMVAIAEDLVRGVSIIHDFGLLHNDIKGDNILLEHRGERWHGVIIDMGLV
Spk369_Spur     IDPILYPSIWNMVAIAEDLVRGVSTIHDFGLLHNDIKGDNILLEHRGERWHGVIIDMGLV
Spk400_Spur     IDPILYPSIWNMVAIAEDLVRGVSTIHDFGLLHNDIKGDNILLEHRGERWHGVIIDMGLV
Spk401_Spur     IDPILYPSIWNMVAIAEDLVRGVSIIHDFGLLHNDIKGDNILLEHRGERWHGVIIDMGLV
                 :*    .  .:: *.:*::.*:  :*. .******* **:*** * :** . ***:*:*

Spk376_Spur     STVTYPHLSGSN-GSMSTHAKGY-FIHTAPEVLK--GCATSVASDVYSVGIILDCIGDFI
Spk383_Spur     STATYPYFSGSN-GSMSTHAKGY-FIHTAPEVLK--GCATSVASDVYSVGIILDCIGGFI
Spk379_Spur     STVTYPYISGSN-GSMSTHAKGY-LIRTAPEVLK--GCETSVASDVYSVGIILDCIGRVI
Spk380_Spur     STIAFPPHVTIKRSVMEDHKKLSGNVYVAPEVVD-DGTTLSKASDIYSVGVLLVFIGRAA
Spk370_Spur     TTMAYTEQRSFS-DLIPESQRLK-FPHIAPELLDSAGSQVSASTDIFAVGVQLNMIGQFI
Spk369_Spur     TTMAYTEQRSFS-DLIPESQRLK-FPHIAPELLDIAGSQVSASTDIFAVGVQLNMIGQFI
Spk400_Spur     TTMAYTEQRSFS-DLIPESQRLK-FPHIAPELLDVVGSQVSASTDIFAVGVQLNMIGQFI
Spk401_Spur     TTMAYTEQRSFS-DLIPESQRLK-FPHIAPELLDIAGSQVSASTDIFAVGVQLNMIGQFI
                :* ::.     . . :    :       ***::.  *   * ::*:::**: *  **

Spk376_Spur     KDDDLCTLVEVCCKEDPKERPGDMEEMLPGVVDIKEKHRTVARLAGESLEEKEEE-----
Spk383_Spur     KDDSLRTLGDMCCKEDPKDRPGDMEEMLPGVVHIKEKHRTVARLAGELLEADTEEEQESE
Spk379_Spur     KDDDLRTLGDMCCKEDPKERPDDMEEMLPEVLEIKEKHRAVARLAGELLEAYIDEE----
Spk380_Spur     RLQGLIAIGESCSQKAPMLRPRSLKDVIPKVRALQEQLAHES------------------
Spk370_Spur     DDDELVTVGEHCCENEPHLRPKALDDIVPKLVEIKTRLKNERRLHR--------------
Spk369_Spur     DDDELVTVGEHCCENEPHLRPKALDDIVPKLVEIKTRLKNERRLHR--------------
Spk400_Spur     DDDELVTVGEHCCENEPHLRPKALDDIVPKLVEIKTRLKNERRLHR--------------
Spk401_Spur     DDDELVMVGEHCCENEPHLRPKALDDIVPKLVEIKTRLKNERRLHR--------------
                  : *  : : *.:: *  **  :.:::* :  :: :

Spk376_Spur     --------EDFLTDLFETGAEEEAEGEMKEGDAEVEVAEDERGEEGLEEEAREEGQVEEE
Spk383_Spur     EEEEERGDEDFLTDLSE---AEEAEGEQNEGDAEV---EDERGKEGLEEDAGEGGQGEEE
Spk379_Spur     -------------------------------------------------------QEEEE
Spk380_Spur     ------------------------------------------------------------
Spk370_Spur     ------------------------------------------------------------
Spk369_Spur     ------------------------------------------------------------
Spk400_Spur     ------------------------------------------------------------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     DGDAWLLHIEGEEPNGEEVQRGAEGEADEEVEEGVAEEDAGEARRHQEVGDEAGEGHREE
Spk383_Spur     DGDAWLLHIEGEEPNGEEVQRGAEEEADEEAEEGVAEEDGGEARRHQEVGDEA-EGDREE
Spk379_Spur     DGDAWLLHIEGEEPNEEEVQRGAEEEADEELEEDLAGEDRGEARRHQEVGDEAEEGDREE
Spk380_Spur     ------------------------------------------------------------
Spk370_Spur     ------------------------------------------------------------
Spk369_Spur     ------------------------------------------------------------
Spk400_Spur     ------------------------------------------------------------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     GNGAGDGEAEQGDAVEGVAGEEAPQGHA---------MRNEEGMDLAVEALHPNADEAQQ
Spk383_Spur     GNEAGDGEAEQGDAGEGVAGEEDLQVHQQGVIAVNDEMRNEEGLELAVEALHPNAEEAEQ
Spk379_Spur     GNEAGDEEAEQGDAGEGVAGEEAPQVHR--------HVRNEEGLELAVEGLHPNAEEAEQ
Spk380_Spur     ------------------------------------------------------------
Spk370_Spur     ----------------------------SGTFVIES------------------------
Spk369_Spur     ----------------------------SGTFVIDS------------------------
Spk400_Spur     ----------------------------SGTFVIDS------------------------
Spk401_Spur     ----------------------------SGTFVIDS------------------------


Spk376_Spur     GGEELMLEDGEEGANDEGGEINDGEGRKKARKLLKKQQIYKFDGGQKESTLSKKQQIKKN
Spk383_Spur     GGEELMLEGGEEGANDEGGERNDGEV----------------------------------
Spk379_Spur     GGEQLMLEDGGEGANEEGGERNDGEV----------------------------------
Spk380_Spur     ------------------------------------------------------------
Spk370_Spur     ---------DENG-----------------------------------------------
Spk369_Spur     ---------DQDG-----------------------------------------------
Spk400_Spur     ---------DQDG-----------------------------------------------
Spk401_Spur     ---------DQDG-----------------------------------------------


Spk376_Spur     LVEGRKKARKLSKKQQIYKFDGGQKESTLSKKQQIIKFGGRQKENQKTLKESADHQIWWK
Spk383_Spur     ------------------------------------------------------------
Spk379_Spur     ------------------------------------------------------------
Spk380_Spur     ------------------------------------------------------------
Spk370_Spur     ------------------------------------------------------------
Spk369_Spur     ------------------------------------------------------------
Spk400_Spur     ------------------------------------------------------------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     AERKPENSQRSSKSSNLVEGREKTRQLSKKQQINKFGGRQRENQTTRKEAANQTFDGRQR
Spk383_Spur     ------------------------------------------------------------
Spk379_Spur     ------------------------------------------------------------
Spk380_Spur     ------------------------------------------------------------
Spk370_Spur     ------------------------------------------------------------
Spk369_Spur     ------------------------------------------------------------
Spk400_Spur     ------------------------------------------------------------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     ENQTTLKEAANHPGWWRAERRPENSQRSSKSTRLVEGRKKATKLPKKQQIIKFDGGERAR
Spk383_Spur     ------------------------------------------------------------
Spk379_Spur     ------------------------------------------------------------
Spk380_Spur     ------------------------------------------------------------
Spk370_Spur     ------------------------------------------------------------
Spk369_Spur     ------------------------------------------------------------
Spk400_Spur     ------------------------------------------------------------
Spk401_Spur     ------------------------------------------------------------


Spk376_Spur     KLPKKQQIKKNLVEGKKKARKLSKKQQIVKFGGGQK
Spk383_Spur     ----------------------------IEEDDGIG
Spk379_Spur     ----------------------------VEEDDEIG
Spk380_Spur     --------------------------------NSGN
Spk370_Spur     -----------------------------SSQGGNG
Spk369_Spur     -----------------------------SSQGGNG
Spk400_Spur     -----------------------------SSQGGNG
Spk401_Spur     -----------------------------SSQGGNG
                                                .