Difference between revisions of "Kinase Family IRAK"
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====Domain Structure==== | ====Domain Structure==== | ||
| + | Metazoan IRAK genes typically have a N-terminal death domain followed by a kinase domain, though several species have duplicates that lack the death domain or have a second kinase domain. | ||
====Functions==== | ====Functions==== | ||
Revision as of 16:06, 30 March 2024
Kinase Classification: Group TKL: Family IRAK
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Evolution
IRAKs are found in metazoans, including 4 genes (IRAK1-4) in vertebrates, single genes in flies and worms, and expansions elsewhere. A very large expansion of IRAK genes is also seen in plants.
Domain Structure
Metazoan IRAK genes typically have a N-terminal death domain followed by a kinase domain, though several species have duplicates that lack the death domain or have a second kinase domain.
