Difference between revisions of "Kinase Family NDR"
From WikiKinome
(Proposed AGC/NDR/RER subfamily for RIM15 and CC1G_14606) |
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I would like to propose a new NDR subfamily that would include Baker's Yeast RIM15 and C.cinerea CC1G_14606 currently at kinase.com. | I would like to propose a new NDR subfamily that would include Baker's Yeast RIM15 and C.cinerea CC1G_14606 currently at kinase.com. | ||
| − | AGC/NDR/RER, where RER indicates response regulator domain. | + | AGC/NDR/RER, where RER indicates the response regulator domain. |
It turns out that these kinases are pan-fungal orthologs: I have seen good copies in Dermatophytes, S.pombe, and others. I will provide evidence when I get time. Since they are pan-fungal and have an interesting domain architecture, I think they deserve their own subfamily. | It turns out that these kinases are pan-fungal orthologs: I have seen good copies in Dermatophytes, S.pombe, and others. I will provide evidence when I get time. Since they are pan-fungal and have an interesting domain architecture, I think they deserve their own subfamily. | ||
Revision as of 14:19, 10 November 2011
HI - my name is Jon Goldberg, a Bioinformatics Scientist at The Broad Institute.
I would like to propose a new NDR subfamily that would include Baker's Yeast RIM15 and C.cinerea CC1G_14606 currently at kinase.com.
AGC/NDR/RER, where RER indicates the response regulator domain.
It turns out that these kinases are pan-fungal orthologs: I have seen good copies in Dermatophytes, S.pombe, and others. I will provide evidence when I get time. Since they are pan-fungal and have an interesting domain architecture, I think they deserve their own subfamily.
