Kinase Family NDR

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Revision as of 14:19, 10 November 2011 by Jmgold (Talk | contribs)

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HI - my name is Jon Goldberg, a Bioinformatics Scientist at The Broad Institute.

I would like to propose a new NDR subfamily that would include Baker's Yeast RIM15 and C.cinerea CC1G_14606 currently at kinase.com.

AGC/NDR/RER, where RER indicates the response regulator domain.

It turns out that these kinases are pan-fungal orthologs: I have seen good copies in Dermatophytes, S.pombe, and others. I will provide evidence when I get time. Since they are pan-fungal and have an interesting domain architecture, I think they deserve their own subfamily.