Difference between revisions of "Kinase Family STE20"
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STE20 kinases are best known as members of the MAPK cascade. Many of them are MAP3K kinases that phosphorylate MAP2K (STE7, MEK) kinases, which in turn phosphorylate MAPK like Erk, Jnk, and p38. However, several subfamilies of STE20 may be only partially involved in MAPK cascades. | STE20 kinases are best known as members of the MAPK cascade. Many of them are MAP3K kinases that phosphorylate MAP2K (STE7, MEK) kinases, which in turn phosphorylate MAPK like Erk, Jnk, and p38. However, several subfamilies of STE20 may be only partially involved in MAPK cascades. | ||
| − | + | The STE20 family has the following subfamilies: | |
| − | + | ||
| − | [[ | + | ====[[Kinase_Subfamily_PAKA|PAKA]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_PAKB|PAKB]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_FRAY|FRAY]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_MSN|MSN]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_KHS|KHS]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_MST|MST]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_SLK|SLK]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_YSK|YSK]]==== |
| − | [[ | + | ====[[Kinase_Subfamily_NinaC|NinaC]]==== |
| − | [[Kinase_Subfamily_STLK|STLK]] | + | ====[[Kinase_Subfamily_TAO|TAO]]==== |
| + | |||
| + | ====[[Kinase_Subfamily_STLK|STLK]]==== | ||
====Evolution==== | ====Evolution==== | ||
STE20 kinases are found in almost all eukaryotes, with Plasmodium being a notable exception. | STE20 kinases are found in almost all eukaryotes, with Plasmodium being a notable exception. | ||
Latest revision as of 07:50, 16 January 2022
Kinase Classification: Group STE: Family STE20
STE20 kinases are best known as members of the MAPK cascade. Many of them are MAP3K kinases that phosphorylate MAP2K (STE7, MEK) kinases, which in turn phosphorylate MAPK like Erk, Jnk, and p38. However, several subfamilies of STE20 may be only partially involved in MAPK cascades.
The STE20 family has the following subfamilies:
PAKA
PAKB
FRAY
MSN
KHS
MST
SLK
YSK
NinaC
TAO
STLK
Evolution
STE20 kinases are found in almost all eukaryotes, with Plasmodium being a notable exception.
