Difference between revisions of "Kinase Subfamily ERK1"
From WikiKinome
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ERK1 ('''E'''xtracellular signal '''R'''egulated '''K'''inase) transduces growth signals downstream of receptor tyrosine kinases, ras, and raf in human cells, and the pheromone response pathway (KSS1/FUS3) in yeast. The subfamily is found in virtually all eukaryotes. The two vertebrate genes, ERK1 and ERK2 have very similar functions, and their upstream kinases are MEK1 and MEK2 (MAP2K1 and MAP2K2). | ERK1 ('''E'''xtracellular signal '''R'''egulated '''K'''inase) transduces growth signals downstream of receptor tyrosine kinases, ras, and raf in human cells, and the pheromone response pathway (KSS1/FUS3) in yeast. The subfamily is found in virtually all eukaryotes. The two vertebrate genes, ERK1 and ERK2 have very similar functions, and their upstream kinases are MEK1 and MEK2 (MAP2K1 and MAP2K2). | ||
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| + | ====Evolution==== | ||
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| + | ====Domain Structure==== | ||
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| + | ====Functions==== | ||
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| + | ====References==== | ||
Latest revision as of 04:15, 10 January 2022
Kinase Classification: Group CMGC: Family MAPK: Subfamily ERK1
ERK1 (Extracellular signal Regulated Kinase) transduces growth signals downstream of receptor tyrosine kinases, ras, and raf in human cells, and the pheromone response pathway (KSS1/FUS3) in yeast. The subfamily is found in virtually all eukaryotes. The two vertebrate genes, ERK1 and ERK2 have very similar functions, and their upstream kinases are MEK1 and MEK2 (MAP2K1 and MAP2K2).
