Difference between revisions of "Kinase Subfamily GEK"
From WikiKinome
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====Evolution==== | ====Evolution==== | ||
| − | GEK kinases are found in animals and some fungi. | + | GEK kinases are found in animals and some fungi. Vertebrates have four members: DMPK1, DMPK2, MRCKa and MRCKb, while most invertebrates have a single homolog. |
====Domain Structure==== | ====Domain Structure==== | ||
| − | + | Most members are ~1800 AA long, with an N-terminal kinase domain, a DMPK-specific domain, followed by C1, PH, CND and PBD domains. DMPK1 is truncated and lacks the last four domains | |
====Functions==== | ====Functions==== | ||
Latest revision as of 04:57, 20 March 2023
Kinase Classification: Group AGC: Family DMPK: Subfamily GEK
This article is a stub
Evolution
GEK kinases are found in animals and some fungi. Vertebrates have four members: DMPK1, DMPK2, MRCKa and MRCKb, while most invertebrates have a single homolog.
Domain Structure
Most members are ~1800 AA long, with an N-terminal kinase domain, a DMPK-specific domain, followed by C1, PH, CND and PBD domains. DMPK1 is truncated and lacks the last four domains
