Kinase Subfamily NDKE

Kinase Classification: Group NDK: Subfamily NDKE

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NDKB is a subfamily of Nucleoside Diphosphate Kinases. It contains two human genes, NME8 and NME9. Both encode thioredoxin domains in addition to dual nucleoside diphosphate domains. While absent from most fungi, a homolog is seen in the chytrid Batrachochytrium dendrobatidis, which has a similar domain architecture, but with four NDK catalytic domains (gi|575480492).