Gene C33F10.2 (Nematode worm)

C33F10.2

Species: Nematode worm
Alias: aSWK243, CE02529, C33F10.2
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: II: 4828545-4832452, WormBase Genetic Map location: II:-2.62,

Classification

Group: Other
Family: TBCK

Sequence

Name Sequence Type Origin Length Description Download
C33F10.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 263 Kinase domain by global Sugen HMM Fasta, JSON
C33F10.2.AA Protein Genbank 826 None Fasta, JSON

Protein domain

Protein domains of C33F10.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C33F10.2.AA TBCK 15-274 38 3.1e-166 558.53 In-house 1-346 (346) Show / Hide 
Range on Protein: 15-274
Range on HMM: 1-346/346
Sequence Identity: 38% (132 aa)

QEKDGRTCINGLPVASPAKQMLGRFPYLQSLQHDNLSVYLHFSETVIARDLVIVVMEHYTMNLED----ILKTGNLKDESLNNNFYSEISSALDYLHTRN
|||..|.|||||||...||||||||.||.||||.||..||.||...|.....|||||||.|||||    ..|....||.|.....|..|...|.|.|...
QEKHDRCCINGLPVTPNAKQMLGRFQYLKSLQHPNLCQYLDFSRGKIHHERMIVVMEHYKMNLEDQIEIYAKRHTPKDCSQILCIYYQILCGLSYMHKHH

IVHGFLHLNSIYITDRKNQKLSVKLSGYGLPFLTNYGKDTASSIKFGAFLAPERILNDEDSLFA----------------ATYQSDVWELGFIILQIYLG
|||.|||...||..|..||||.|||..|||...||.|||....|......||||||..|.....                ....||||.||.|.|.|.||
IVHRFLHPHNIYLDDNGNQKLHVKLANYGLYHMTNHGKDVPFPIGYPRYMAPERILQGEMKTTDHMPPTNPLPPKTTNLSSNPKSDVWSLGCIMLEICLG

ISLEAEVTETEYLEILNKYYTD-------------------------------------------------------DQEKLSTVMEDLIQLLADKKR--
|.|..|.|..|.|.....|.|.                                                       ||......||||........|  
ICLWQELTLSEVLNKIMHYGTHSTTQSFNSISKSFEQCELKKTIINEKQHEEYEEYDDDEDISEEEKEKRIKDIKLNDQDCMNHFMEDLAREHQCHQRSN

---------LPYHKKCEWLEAIIRKCLQMCCSKRCSITEVAAEIEI
         .|||..||||..|||||||||..||.|.||.......
SGSSNSNIGIPYHQMCEWLIQIIRKCLQMCPMKRPSPTELMEHPMF
Kinase C33F10.2.AA C8 103-188 21 1.6e-07 22.34 In-house 136-226 (226) Show / Hide 
Range on Protein: 103-188
Range on HMM: 136-226/226
Sequence Identity: 21% (20 aa)

LDYLHTRNIVHGFLHLNSIYITDRKNQKLSVKLSGYGLPFLTNYGKDTASSIKF-----GAFLAPERILNDEDSLFAATYQSDVWELGFII
..|.|  ||.|  . .. . .   .|.  ..||.  |.       |.   |.|.      |..||| .  ... .   . |||....| . 
VNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase C33F10.2.AA Ciliate-E6 68-123 30 1.7e-07 20.27 In-house 27-86 (154) Show / Hide 
Range on Protein: 68-123
Range on HMM: 27-86/154
Sequence Identity: 30% (18 aa)

VVMEHYTMNLEDILKTGNLKDESLNN----NFYSEISSALDYLHTRNIVHGFLHLNSIYI
.|||   |||.| ..   .|.   .|    .|  ....|..|||  |.|.. . | .|..
IVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFL
S_TKc C33F10.2.AA S_TKc 10-274 14 2.9e-07 -70.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-274
Range on HMM: 1-231/231
Sequence Identity: 14% (44 aa)

FIL-------------RAQEKD-GRTC----INGLPVASPAKQMLGRFPYLQSLQHDNLSVYLHFSETVIARDLVIVVMEHYTM---NLEDILKTGNL--
. .             ....|. || .    |.        ....     |.. .|.|.  .. . ..    | . .|||.      .| |..|  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----KDESLNNNFYSEISSALDYLHTRNIVHGFLHLNSIYITDRKNQKLSVKLSGYGLPFLTNYGKDTASSIKFGAFLAPERILNDEDSLFAATY-QSDV
     .|     .  .| .||.|.| ..|.|  |    | ...       .|..  ||  .    .    .     ..||| .          ..  .|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL---TTFCGTP---WYMAPEVL--------GYGKCKCDW

WELGFIILQIYLGISLEAEVTETEYLEILNKYYTDDQEKLSTVMEDLIQLLADKKRLPYHKKCEWLEAIIRKCLQMCCSKRCSITEVAA-------EIEI
| .| |.   . |  .    .. . ....                                  . .  .||||||.  .|| .. |. .          .
WSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase C33F10.2.AA AGC 97-113 36 1.5e-05 8.72 In-house 153-177 (395) Show / Hide 
Range on Protein: 97-113
Range on HMM: 153-177/395
Sequence Identity: 36% (9 aa)

SE-------ISSALDYLHT-RNIVH
.|       | .||.|||  ..|.|
AEMQKICGCIVLALEYLHSHMGIIH
Kinase C33F10.2.AA Aur 97-113 52 0.000139 7.46 In-house 108-124 (257) Show / Hide 
Range on Protein: 97-113
Range on HMM: 108-124/257
Sequence Identity: 52% (9 aa)

SEISSALDYLHTRNIVH
..| .||||.| .||.|
YQICNALDYCHSKNIIH
Kinase C33F10.2.AA ARMK 98-134 45 0.000141 12.97 In-house 131-166 (362) Show / Hide 
Range on Protein: 98-134
Range on HMM: 131-166/362
Sequence Identity: 45% (17 aa)

EISSALDYLHTRNIVHGFLHLNSIYITDRKNQKLSVK
|||.|. |||  ||||  ||.| | | .|   .  ..
EISKAMTYLHSHNIVHRSLHPNNILI-NRVDGNIYIR
Kinase C33F10.2.AA SGK 97-113 47 0.000197 9.08 In-house 132-148 (283) Show / Hide 
Range on Protein: 97-113
Range on HMM: 132-148/283
Sequence Identity: 47% (8 aa)

SEISSALDYLHTRNIVH
.|| .||.|||  .|..
AEIVCALEYLHSQDIIY
Kinase C33F10.2.AA CMGC 69-113 15 0.000212 9.35 In-house 133-207 (513) Show / Hide 
Range on Protein: 69-113
Range on HMM: 133-207/513
Sequence Identity: 15% (12 aa)

VMEHYTMNLEDILKTGN----------LKDES-----------LNNNFY------SEISSALD--YLHTRN--IVH
|.|.  ..| ...|  .          |..             .  .|         |  .|.  |.| ..  |.|
VFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIH
Kinase C33F10.2.AA Ciliate-C3 99-134 38 0.000228 12.02 In-house 105-140 (140) Show / Hide 
Range on Protein: 99-134
Range on HMM: 105-140/140
Sequence Identity: 38% (14 aa)

ISSALDYLHTRNIVHGFLHLNSIYITDRKNQKLSVK
|  |.||||  ||||| . .  | |  ... |.   
ILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase C33F10.2.AA TKL 98-192 14 0.000327 11.08 In-house 140-283 (364) Show / Hide 
Range on Protein: 98-192
Range on HMM: 140-283/364
Sequence Identity: 14% (21 aa)

EISSALDYLHTRN--------IVHGFLHLNSIYITDRKN----------QKLSVKLSGYGLPF-LTNYGKDTAS----------------SIKFG---AF
.|.....|||..|        |.|  |  . | . .  .              .|.. .||   ... |.....                ... .   ..
DIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRW

LAPERILNDEDSL-----------FAATYQSDVWELGFIILQIY
.||| . ....             | .. ..||.  | ..  |.
MAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEIL
Kinase C33F10.2.AA Pkinase 41-113 20 0.007469 11.17 Pfam 53-131 (293) Show / Hide 
Range on Protein: 41-113
Range on HMM: 53-131/293
Sequence Identity: 20% (17 aa)

YLQSLQHDNLSVYLHFSETVIARDLVIVVMEHYTM-----NLEDILK--TGNLK--DESLNNNFYSEISSALDYLHTRNIVH
....|.|.|   .... |.   .| . .|||.  .      | |...   ..    .|    ..  .| ..|.|.| ..|.|
IMKRLNHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH
Kinase C33F10.2.AA Pkinase 245-272 20 0.407176 5.03 Pfam 264-293 (293) Show / Hide 
Range on Protein: 245-272
Range on HMM: 264-293/293
Sequence Identity: 20% (6 aa)

EWLEAIIRKCLQMCCSKRCSITEVAAE--I
|..  .|..||.....||......     .
EECKDFIKWCLCKDPKKRPTAEQILQHPWF
TBC C33F10.2.AA TBC 444-657 23 1.6e-68 234.89 SMART 1-310 (310) Show / Hide 
Range on Protein: 444-657
Range on HMM: 1-310/310
Sequence Identity: 23% (72 aa)

TNIGVIPTQRADVWCTLLDI----------------------------NETKWRDYLNLDVLASHSS-----------------------------DRQL
.  |. .. |..||. ||..                            ........||     .|..                             . | 
WWQGIPHHYRGWVWWLLLNCQPMNTSNWERMQYMWDGENCYFPVNWDRCKDYYDRMLNQHCPCDHHHDNWQDIMMNNNDHECCWMSYWHFFQDCWHWHQI

EVDIPRCHQYDSYMTTP---------------AIQESLRKVLKGWQIVTESQH-FVYWQGCDSLATPFLLANM-SKPHVAFACFKEFTYRYCHKFY----
|.|..|... .... ..               ..|||||.||. . ..... | ..|.||.  .|.|.|| .. . .. ||.||.....|||..||    
EKDLRRTFPNHPFFQFRMRYNQHCIMLHDQNGPHQESLRRVLYAYSWHNPE-HIVGYCQGMNFIAAPLLLHMPCYDEEDAFWCFCKLMERYCPWFYFCDD

----LKDNSEVIKEYLGIFYHLVAYTDPVLYKHLKI------------NGFDAELFAIPWFLTCFAHELPLSKLVLLWDETMMH----GNAFPLMIALAM
    ..| ... . .. .. .|  . || |||||..            ...|....|..|||||||.|.||  .. .|| ....    |. |...|||||
QNCYTPDMMGMHWQMYQFDHLLQEH-DPDLYKHLQEQDHHSMKWHFDHLEIDPSMYAFRWFLTCFAREFPLEDVCRIWDCYFFEYGRHGHPFLFCIALAM

LNRLRDKLLAVN
|. .|.|||  .
LKMHRQKLLQHD
TBC C33F10.2.AA TBC 450-654 22 3.9e-43 154.43 Pfam 1-240 (240) Show / Hide 
Range on Protein: 450-654
Range on HMM: 1-240/240
Sequence Identity: 22% (55 aa)

PTQRADVWCTLLDINE-----------------TKWRDYLNLDVLASHSSDRQLEVDIPRCHQ-YD--SYMTTPAIQE-SLRKVLKGWQIVTESQHFVYW
.. |..||..||....                  ..  |  ..  . |. ..| | |..|... ..  ...... .|. .||..|| . .  .     |.
DQLRWQVWPYLLGYYPWMNGYYKRLYYQEKKQWYQMK-YQ-NNYHEPHPDYHQIEKDVHRTFPNHHHFFFFQNGQGQQVQLRNILKAYSNYNPD--VGYC

QGCDSLATPFLLANMSKPHV-----AFACFKEFT--YRYCHKFYLKD-NSEVIKEYLG--IFYHLVAYTDPVLYKHLKI--NGFDAELFAIPWFLTCFAH
||   .| |||.  |   .      || ||  .     ... .|..| .  ... ..   .| .|. . || ||||..   .. |  .||..||...|.|
QGMNFIAAPFLYMYMMDEEDFQAEDAFWCFCQLMNENYHLRDYYTHDMPG-HLQRDFYFQVFEELLKKHDPKLYKHFQKDCLNIDPSMFATQWFMCLFTH

ELPLSKLVLLWDETMM--HGN---AFPLMIALA-ML-NRLRDKLL
..|.. .. .||  ..  .|     | . ..|| .|  ..|...|
CFPFETVLRIWDCFFFYCEGWNAKFFLFRFCLACILVKYHRQEIL