Protein (view, download) , Domain (view, download)
TNK1_Hsap       ML---------------------------------P----E----A-GS----LWLLKLL
Ack_Dmel        MRGPLTARHQNQQPSRQLLIWRE----------MTSTSAVDGGLGS-ET----AWLEDLL
PR2_Dmel        MVKR-------------------------------E----E----APGGG-SQVALD---
ACK_Mmus        MGERSAYQR---------LARGEEGQQRLGSSSMQP----E----E-GT----GWLLELL
kin-25_Cele     MA---------------------------------S----T----S-GALVD-DNVLEVL
ark-1_Cele      MREE-------------------------------P----T----A-GTA-D-ATLNKLL
TNK1_Mmus       ML---------------------------------P----E----A-SS----LWLLRLL
ACK_Hsap        MGERSAYQR---------LAGGEEGPQRLGGGRMQP----E----E-GT----GWLLELL
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       MKET-------------------------------E----E----G-GD----GRIHALV
Ack3_Spur       ---------------------------------------------E-GA----QWLEELL


TNK1_Hsap       RDIQLAQFYWPILEELNVTRPEHFDFVKPEDLDGIGMGRPAQRRLSEALKRLRSGPKSKN
Ack_Dmel        REVQLEQFLDRIRDDLQVTRLAHFDYVLPDDLERCGLGKPAIRRLMEAVRKKKAHQWRKN
PR2_Dmel        ------------------------------------------------------------
ACK_Mmus        SEVQLQQYFLRLRDDLNITRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKAMCKRKS
kin-25_Cele     RKAQLDAFISQFVFLFNVRRFDHFSHVRDKDMLEIGMQQVQIRQLREQILKMSREMWNRS
ark-1_Cele      QAADLSGYESDLRRKLKLRNAADLQYVEEVDLLSVGMSRPEQKRLRKEYTKM--------
TNK1_Mmus       RDVQLAQFYRPILEELNVTRPEHFDFVRPEDLDNIGMGRPAQRRLNEALKRYRSGVKSKN
ACK_Hsap        SEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKS
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       L---------------NV--------VKPG----------------DSVNRSRAANSSQ-
Ack3_Spur       EETQLQKFLTKIHDDLQVSRLDHFQYVRTEDLEKIGMGRPAARRLLEAVKRRRRRSGSQS


TNK1_Hsap       WVYKILGGFA------PEHKEPTLPSDSP--R--HLPEPEGGLKCLIPEGAVCRGELLGS
Ack_Dmel        ILSKLIGGGK----QPSSKKQSS-----A--ARESSQGNGTQLTCLIHEKDITMGLKLGD
PR2_Dmel        ------GS------SASA-CSSL-AAKNG--A--SSPSKVPNNKHIIPADSISVNKQLGT
ACK_Mmus        WMSKVFSGKRLEAEFPSQHSQSTFRKPSPTPGSLPGEGTLQSLTCLIGEKDLRLLEKLGD
kin-25_Cele     DPKQV-----------------YIQADQS-----MPAQNSIDEKALIPNEQIKLYELIGE
ark-1_Cele      FPSGIFGKVK----KAFKRAESL-DRKTS--N--SVANQDDNDHHVIPIEKITLCKELGQ
TNK1_Mmus       WVYKILGGFA------PEQKEIPPRSDSP--L--CFHEPEGGLKCLIPEGAVRRGELLGS
ACK_Hsap        WMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGD
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ---------------P-------ATQPLPSGV-TSTRQNMESLTCLISESELTLHEKLGN
Ack3_Spur       ILGRVAVVKRLTVRYPTAHNKSFNRKPSGFDRRLNGIGDIRDVTALIAEREEERERKSGR


TNK1_Hsap       GCFGVVHRGLWTL-PSGKS-VPVAVKSLRVGPEGPMGTELGDFLREVSVMMNLEHPHVLR
Ack_Dmel        GSFGVVRRGEWSASPAGKV-IPVAVKVLKSDNLTQ-PGIIDDFFREVQAMHALDHANLVR
PR2_Dmel        GEFGIVQQGVWSN--GNER-IQVAIKCLCRERMQS---NPMEFLKEAAIMHSIEHENIVR
ACK_Mmus        GSFGVVRRGEWDA-PAGKT-VSVAVKCLKPDVLSQ-PEAMDDFIREVNAMHSLDHRNLIR
kin-25_Cele     GSFAVVKRGTWTQ-SNGTH-VNVAVKILRD--I-S-PNIMDDLRVEASHLLKLQHPSLIR
ark-1_Cele      GEFGSVWQAGWKN-SAGSDVIQVAVKCVGSDKLLA---TSSSFLQEAAIMTRMRHEHVVR
TNK1_Mmus       GCFGVVHRGLWTL-PSGQS-IPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLR
ACK_Hsap        GSFGVVRRGEWDA-PSGKT-VSVAVKCLKPDVLSQ-PEAMDDFIREVNAMHSLDHRNLIR
Ack1_Spur       --------------------IPVAVKCLSPEKLSL-DKCQQDFLKEAAIMHSLNHEHLVK
Ack2_Spur       GSFGVVRRGDWKT-PRGKR-VEVAVKCLRSEMVNQ-PGFFEDFVKEVNTMHLLDHPHLVR
Ack3_Spur       AKFGMVKHEKWSL-CTGSF-STVSMRCLRYEVAGS-EELVDGFLPNFSYMYLVEPEELIR
                                      *::: :              :  :   :  :    :::

TNK1_Hsap       LHGLVLG--QPLQMVMELAPLGSLHARLTAPAPTPP-LLVALLCLFLRQLAGAMAYLGAR
Ack_Dmel        LYGVVLS--QPMMMITELAERGSLLDTLRKQCR--H-TSLTIIWNWSVQIVTGMAYLEQK
PR2_Dmel        LYGVVLAT-DSLMLVTELAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLEQK
ACK_Mmus        LYGVVLT--LPMKMVTELAPLGSLLDRLRKHQG--H-FLLGTLSRYAVQVAEGMAYLESK
kin-25_Cele     LYGIVR---QPAMMVFELCEGGSLLDRLRDDK-KAI-LLVSRLHDYCMQIAKALQFLESK
ark-1_Cele      LYGVVLDT-KKIMLVSELATCGSLLECLHKPALRDS-FPVHVLCDYAEQIAMGMSYLELQ
TNK1_Mmus       LHGLVLG--QPLQMVMELAPLGSLHARLTAPAPTPP-LPVALLCLFLRQLAGAMAYLGSC
ACK_Hsap        LYGVVLT--PPMKMVTELAPLGSLLDRLRKHQG--H-FLLGTLSRYAVQVAEGMGYLESK
Ack1_Spur       LYGVVLDVDSSLMLVTEFAPLRSLAENMKQEALKPA-FPITLLLDFSVQITDAMRYLHMS
Ack2_Spur       LYGVVLS--SPLKMVTELAPLGALVDRLREDPS--K-FLISTLSAFALQIASGMSFLEYK
Ack3_Spur       FWGYE-------------------------------------------------------
                : *

TNK1_Hsap       GLVHRDLATRNLLLASP----RTIKVADFGLVRPLGGARGRYV--MGGPRPIPYAWCAPE
Ack_Dmel        RFLHRDLACRNVLLAAG----NKIKIGDFGLMRALPQEDDCYV--MSEHKKVPFPWCAPE
PR2_Dmel        RLIHRDLAARNILVFSK----DKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPE
ACK_Mmus        RFIHRDLAARNLLLATR----DLVKIGDFGLMRALPQNDDHYV--MQEHRKVPFAWCAPE
kin-25_Cele     HCVHRDVAARNILLARD---ERTVKICDFGLMRALKENEQMYT--MAPQKKVPFAWCPPE
ark-1_Cele      RLIHRDLAARNVLVFSP----KLVKISDFGLSRSLGIGEDYYRSEFTPNLKLPIAWCAPE
TNK1_Mmus       GLVHRDLATRNLLLASP----RMIKVADFGLVRPLGGARGRYV--MGGPRPIPYAWCAPE
ACK_Hsap        RFIHRDLAARNLLLATR----DLVKIGDFGLMRALPQNDDHYV--MQEHRKVPFAWCAPE
Ack1_Spur       NIIHRDLAARNILLFVDDEGNKKAKISDFGLSRRLLLGENYR-SEMRPNLKLPLAWMPVE
Ack2_Spur       RFIHRDLAARNILLASM----QKVKIGDFGLMRALPSATNYYI--MTEHNQVPYA-----
Ack3_Spur       ------------------------------------------------------VXCAPE


TNK1_Hsap       SLRHGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLE-D-RARLPRPPLCSRA
Ack_Dmel        SLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDRE-GERLHQPDACPPD
PR2_Dmel        CINYLRFTNASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPSE
ACK_Mmus        SLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKE-GERLPRPEDCPQD
kin-25_Cele     ALRHRKFSHASDVWSYGVTIWEVFTFGEEPWVGCRAIDVLKNID-A-GERLEKPKYCSER
ark-1_Cele      CINFLKFTSKSDVWAYGVTIWEMFSYGEMPWKGRSGAQILELVDRK-KELLTRPKACPED
TNK1_Mmus       SLRQGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKD-RARLPKPPLCSRA
ACK_Hsap        SLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKE-GERLPRPEDCPQD
Ack1_Spur       SLTKLTFTKASDVWSFGVTMWEMFSYGRKPFAHLSGEEVITS------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       SLKTKQFSHASDMWMFGVTLWEMFSFGEEPWLGYNGAQILQKIGKE-GERLPRPDHCPPG


TNK1_Hsap       LYSLALRCWAPHPADRPSFSHLEGLLQEAGPSEA--CCVRDVTEPG--ALRMETGDPITV
Ack_Dmel        VYAMMLQCWDKTPAERPTFAALKEYLASMSPPVM--RASRSHHESK--GLQIEPGDTIAI
PR2_Dmel        YYTLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQL--KAVVNCTEPKKDHLLYRQGDIISV
ACK_Mmus        IYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDM--RALQDFEEPD--KLHIQMNDVITV
kin-25_Cele     IYQIMKNCWKFNPAERCKFGAIREDLVAAMFLDAVARETYNSIQPG--ALQLTKGDEVVV
ark-1_Cele      IYDMLKETWTHQVQDRPTFSDIVAKFPERRAQSV--RAVVDCKDSAADHLHFKKDDLIVV
TNK1_Mmus       LYSLALRCWAPHPADRPSFSNLEGLLQEAWLSEG--RCVREVTEPG--ALRMEPGDPITI
ACK_Hsap        IYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDM--RALQDFEEPD--KLHIQMNDVITV
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       IYSLMEICWQANPEDRPMFSSVKDQLDKMKPLEM--RVTKDFDEPD--KLECEEGQIITI


TNK1_Hsap       IEGSSSFHSPDSTIWKGQNGRTFKVGSFP-ASAVTLAD-AGG------------------
Ack_Dmel        IDGRH-----ELKLIKGQNQRTFDIGIFP-RNLLEQRKVGAA------------------
PR2_Dmel        LDRNT-----GTPFWKGV-LSTGKTGYFNPSNTVAFLEGLPS---STRDS----------
ACK_Mmus        IEGRA-----ENYWWRGQNTRTLCVGPFP-RNVVTSVAGLSA------------------
kin-25_Cele     VENTG-------QDWFGQNKKNQKFGTFP-RSVVFAQT-NNAVAAATAVTPQKVPTAPTI
ark-1_Cele      ISRSPAQ-YPDGYYWFGS-LRNGKLGLFRPTDTVAHLGSEPP---CSNGT--------IE
TNK1_Mmus       IEGSL-----DTATWKGQNGRTLKVGNFP-ASAVTLAD-LGG------------------
ACK_Hsap        IEGRA-----ENYWWRGQNTRTLCVGPFP-RNVVTSVAGLSA------------------
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       IDGKP-----EENWWLGQNIHTHKIGRIP-RKLLAPMSGITG------------------


TNK1_Hsap       ---------------------------LPATRPVHRGTPA--RGDQ----HPGSID----
Ack_Dmel        ---------------------------GDV---VMRSSVGNGSSSSPFGFCWGGAAAMAN
PR2_Dmel        ---FS--------RVSDHRISKRKLRTEMISKPQ-NDFKHTGHVGID-GATFGDIAFLG-
ACK_Mmus        ---------------------------QDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDE
kin-25_Cele     RIPPSHPPPAPLKPLNNNTKTSLNDRTSKISMPVAGSFIHTGHGDPLGGQSWGNPATIAD
ark-1_Cele      NG-FSEKEKGGKKNKKAEKESERERKKLLISEPV-GDVRHTCHVGID-GTAFGLLQLDK-
TNK1_Mmus       ---------------------------SPVTHPAHRGSPA--HGEK----CRGGTD----
ACK_Hsap        ---------------------------QDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDE
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ---------------------------EDISKPIKYSFIHTGHGGVD-GNTWGHPDKIDE


TNK1_Hsap       ------------------------------------------------------------
Ack_Dmel        GDDRQRKCASMTNQPHAKERKSTSSKQFAYNKLVNDSATGLQRRNAVKHKGVV--VGPQR
PR2_Dmel        ---------SSQNYNHVPKQI-------------------VTPYKPSEDIEQTPLLLPPT
ACK_Mmus        LYL-----GNPMDPPDLLSVE-------------------LSTSRPTQHLGRVKREPPPR
kin-25_Cele     MYL-----KNPVNGAPLSSMSSGA---------------EIIASKELLTNGGRST-HQPA
ark-1_Cele      ---------KAM-------CP--------------------TSSSPS--TSRG-SQASPA
TNK1_Mmus       ------------------------------------------------------------
ACK_Hsap        LYL-----GNPMDPPDLLSVE-------------------LSTSRPPQHLGGVKREPPPR
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       LYD-----DVPNEAGDASTVT-------------------AEVSK--------KSQ-PPA


TNK1_Hsap       ------------------------------------------------------------
Ack_Dmel        PP---------PPQ-FQQEG----------------------------------------
PR2_Dmel        PT---------SPDSLQTASGYFPEGANSGGAMGTSMNPTFIPSAEHTPKLIATNGQSSF
ACK_Mmus        PP---------QPAIFTQKT----------------------------------------
kin-25_Cele     AP---------SPAVMSKIRG---------------------------------------
ark-1_Cele      PS---------HTSSSTTSSVHL-------------------------------------
TNK1_Mmus       ------------------------------------------------------------
ACK_Hsap        PP---------QPAFFTQKP----------------------------------------
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       RSYYGNQQIIADAAALEDTP----------------------------------------


TNK1_Hsap       ------------------------------------------------------------
Ack_Dmel        ---------------------------------------------------ILIDISPD-
PR2_Dmel        DFASGSTNPFFPNRGDDELEFGLHNYGADGKSVHSETGWRPTSRSIVDDPHEYHEISDDE
ACK_Mmus        ---------------------------------------------------TYDPVSED-
kin-25_Cele     ---------------------------------------------------LSLDL-PE-
ark-1_Cele      ----------------------------------------------------RETVARNG
TNK1_Mmus       ------------------------------------------------------------
ACK_Hsap        ---------------------------------------------------TYDPVSED-
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ---------------------------------------------------TYDDVPNE-


TNK1_Hsap       ------------------------------------------------------------
Ack_Dmel        -----------MRPIA---------------------EAG--------------------
PR2_Dmel        IA--AD--KLDFGPSLLDEINSMFGSISAATGSHPKSPGFD-HVNNKNEITEMS------
ACK_Mmus        -----------PDPLS---------------------SDFK-RLGLRKPALPRG------
kin-25_Cele     -----------YDDFD---------------------RAFDDGFSPSKIELPREFCGNDS
ark-1_Cele      VPIKETMSLRDVGPLSRD--------------ALNLRDTVS-PPVARAPSQPPS------
TNK1_Mmus       ------------------------------------------------------------
ACK_Hsap        -----------QDPLS---------------------SDFK-RLGLRKPGLPRG------
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ------------SNLS---------------------SD-----TLSKNATAKG------


TNK1_Hsap       -----------------------------------------G------------------
Ack_Dmel        -------------------------TG---------GAKGAGDSSSLQADSSFCILDAPI
PR2_Dmel        --------AKLGQKSGD-----TNGNKHGHGLLPTLSKKKSSGTVKPISVKDEKILNHAI
ACK_Mmus        --------LWLAKPSAR-----VPGTK---------ADRSSGGEVTLIDFGEEPVVPTPR
kin-25_Cele     VISGGSNSIGLANTYVM-----EPPKQ---------AFDIRGNRV-LPPTNKAPVLIPTN
ark-1_Cele      --------YSQPRPPPRSVSSVSSGNQHSVQ---------VHDQFSSLDRSRGSLTPTAP
TNK1_Mmus       -----------------------------------------G------------------
ACK_Hsap        --------LWLAKPSAR-----VPGTK---------ASRGSGAEVTLIDFGEEPVVPALR
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       --------DWV-------------------------------------------------


TNK1_Hsap       ----------------------------DRKKAN--------------------------
Ack_Dmel        ---------------------------------------------------------DVP
PR2_Dmel        EIANEISA----------------------------------------------------
ACK_Mmus        ---------------------------------------------------------PCA
kin-25_Cele     P-APSVISSTASAGITLSTNSSQMFTSQDRHSNMPANLFPELQHRLNQGSSTGNGVRPRP
ark-1_Cele      PLTASAANSLKDPLTGISLSIP--------------------------------------
TNK1_Mmus       ----------------------------DREKAT--------------------------
ACK_Hsap        ---------------------------------------------------------PCA
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ------------------------------------------------------------


TNK1_Hsap       ------------LWD---------------------------------------------
Ack_Dmel        TYA-----GSSGSGDL---------------------NVSPTYYNE--------------
PR2_Dmel        -------RSMIDLVSDQTP----VI-------------HSPKRKFSFRFPHLSNNGSGDK
ACK_Mmus        PSLAQLAMDACSLLDKT-P------------------PQSPTRALP--RP----------
kin-25_Cele     ASSIGIQNNDLSMLNPQ-Q------------------PANIPCLVP--TP----------
ark-1_Cele      ------SNNLISYMDDQEDDHRWTRSPGAISQSTTLTALSSSRKDPIPAP----------
TNK1_Mmus       ------------LQD---------------------------------------------
ACK_Hsap        PSLAQLAMDACSLLDET-P------------------PQSPTRALP--RP----------
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       -----------NFYDDV-P------------------TESDLAKLE--SK----------


TNK1_Hsap       --------APPARGQR------------------------RNM-----------------
Ack_Dmel        -----------QPQFDFDPAKMTASPGRLQPPPYQMPPTYSNTMEFVQKRDLHQQQLATP
PR2_Dmel        SGGLGTSGSAHTPT-HGNAS------------PFPKKKNFTEE-----------------
ACK_Mmus        --------LHPTPVVDWDAR------------PLPPPPAYDDV-----------------
kin-25_Cele     --------APPAPAHFS------------------QPVSSQRV-----------------
ark-1_Cele      --------RGPVAAVYARGK------------DIPTPASKSDI-----------------
TNK1_Mmus       --------LPPARSHR------------------------TKM-----------------
ACK_Hsap        --------LHPTPVVDWDAR------------PLPPPPAYDDV-----------------
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       --------AGPLPLRTYDEV------------PVDEPRVFPQD-----------------


TNK1_Hsap       PLE--RMKGISRSLESVL------------------------------------------
Ack_Dmel        VRE--RDPFDTTNVETTVAL-----------------------YSNFNQS---------L
PR2_Dmel        L--QSIPD-----IQSLIGKEGLEAYNSLIERKALLDIGPSPAATLLRHLDTDEFDLQSL
ACK_Mmus        AQD--EDDFEVCSINSTLVG-------------AGLPAGPSQGETNYAFV---------P
kin-25_Cele     AQQ--QQNTLQKALNDEL------------------------------------------
ark-1_Cele      ALCEKIED-----LNRDLTNYSIGTICDY---------------------SEDRPLLDSM
TNK1_Mmus       PLQ--RMRGISKSLESVL------------------------------------------
ACK_Hsap        AQD--EDDFEICSINSTLVG-------------AGVPAGPSQGQTNYAFV---------P
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       M--QDL------------------------------------------------------


TNK1_Hsap       -----------SLGPRPTGGGSSPPEIRQA-RAV--------------------------
Ack_Dmel        EAASPPAPIYNSPSVR---------KSLF----GGSKSNKENIPALESAAMQL----NLS
PR2_Dmel        HQSQRP------MTLPTRGATQRVRKAELAA-G-LSRHNDENSNSLEACE-------SPS
ACK_Mmus        EQAQMPPALEDNLFLPPQGGGKPPSSVQTAE--IFQALQQECMRQLQVPTGQL----TPS
kin-25_Cele     ---------KGNLNKRPTGTTAPPSNGFNAPRADVAPVQQRPISSASIP--AL----QPQ
ark-1_Cele      NRTI-----------SSSTTHQPPPQSSEAR-I-RFMTEQEVRKINEKSA--REHRKTED
TNK1_Mmus       -----------SLGPRPTGGGSSPPELRRT-RAM--------------------------
ACK_Hsap        EQARPPPPLEDNLFLPPQGGGKPPSSAQTAE--IFQALQQECMRQLQAPAGSP----APS
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       --------------------QQPPSSSHKVV--RLQVLHQECQRPGWEPKSGT----SSS


TNK1_Hsap       -----------------------PQ---------GP------------------------
Ack_Dmel        NLTLERH-----------DATCIQPVEPVP-APPG--D---GVLLDKSFIAELE---KDM
PR2_Dmel        YMTHGSYKFPEAQPTEQLPEPESPNP--IP-LPPR--EGKKQVKTSTKRHVRKYPL---I
ACK_Mmus        P-TPGGD-----------DKPQVPPR--VP-IPPR--PTRPRVELSPAPSGEEE---TSR
kin-25_Cele     P-IQH-I-----------QKPIQPQQ--VR-IPPSTAPVQKPVQVSAPTHSNVAPTTSSQ
ark-1_Cele      LLR-EE-RQKEQKP-GEIEEPQQPAE--SL-YSTR--TPQQEGWSSAAQEAYKLLV---E
TNK1_Mmus       -----------------------PQR--LPDLPPRP------------------------
ACK_Hsap        P-SPGGD-----------DKPQVPPR--VP-IPPR--PTRPHVQLSPAPPGEEE---TSQ
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       P-SPTGE-----------D------------VPPA--V----------------------


TNK1_Hsap       -----------------------PGLPPRPPLSSSS------------------------
Ack_Dmel        YSNGQNRAQEEYQRNSTQMYASKDMV-YKQNLTPLKNGAAPGSVHSNHSSPS--------
PR2_Dmel        IPAN----------------GLQ--RT-LSKLADFGDEAAKSPEISTSSQPQPGRAIENL
ACK_Mmus        WPGP----------------ASPPRVPPREPLSPQGS-RTPSPLVPPGSSPLPHRLSSSP
kin-25_Cele     ASAD----------------AR-NPLPPKT--SPPVS-NTPITVAPVHAAPTTSAPSTSV
ark-1_Cele      CGTN----------------LKQASVS-PPPMSPTSS-RL-STLDRSSISPAPPRPVTPP
TNK1_Mmus       -----------------------PDLPPRPPIICNS------------------------
ACK_Hsap        WPGP----------------ASPPRVPPREPLSPQGS-RTPSPLVPPGSSPLPPRLSSSP
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       --------------------------------GPHQS-N---------------------


TNK1_Hsap       ------------------------------------------------------------
Ack_Dmel        ---------ST-ASPKQNNVEAAAAAA----ATT------------------QSVVNRIW
PR2_Dmel        DKLTPADAAGLTDTASLQFESIMEADT----SKE------------------GILQSPDV
ACK_Mmus        GKTMPTTQSFA-SDPKYATPQVIQAPG----PRA------------------GPCILPIV
kin-25_Cele     VTRRPTSTTAQMSDEERRSRIAMDISSALPAPSALLYGSNSTSSLPSAAVSTASSVPSTA
ark-1_Cele      LSVRNETISMRKSQQEEMEHVTVEENS----PKR------------------VHIIE---
TNK1_Mmus       ------------------------------------------------------------
ACK_Hsap        GKTMPTTQSFA-SDPKYATPQVIQAPG----PRA------------------GPCILPIV
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       -------------------------QQ----PPG------------------GSMILPIM


TNK1_Hsap       ------PQ---PSQPSRERLPWPKRKPP--------------------------------
Ack_Dmel        YEQV---A---STQSEYYA---QPPTEQAEEQIYQ-------------------------
PR2_Dmel        TDGF---YNFSIQKEHYNK---GKD--AE-FEATQISGLYVNDDELRNLDIESSRRTATP
ACK_Mmus        RDGR---K---VSSTHYYL---LPERPPYL-ERYQ-------------------------
kin-25_Cele     RDNPVETR---PSQPHVTM---PPKKSSEP-ILSS-------------------------
ark-1_Cele      -----------------------------------------------------TKLIDGP
TNK1_Mmus       ------SQ---PTQPHKAR---PKRESS--------------------------------
ACK_Hsap        RDGK---K---VSSTHYYL---LPERPSYL-ERYQ-------------------------
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       KDGV---Q---VSHTHYYL---LP------------------------------------


TNK1_Hsap       ------------------------------------------------------------
Ack_Dmel        ----NHRHQQQQQQELNHSFV----AISNRVVAPKN--NAYSSTASLYDAVAASTAGSTY
PR2_Dmel        CSSCSALESEHSQPDALPSTE-SVS--EVSRFSSVDNELAG----------NA------L
ACK_Mmus        ----RFLREAQSPEEPAAL------PVPPLLPPPST--PAP----------AA------P
kin-25_Cele     ----EVLQPTRLPSATTSQAKPVTQPIRHPSPPVAT--VIP----------TA------V
ark-1_Cele      ARGMSPIQDRHIPAFTTPMSNGSFR--KAPAPTPVS--PAP----------AG------S
TNK1_Mmus       ------------------------------------------------------------
ACK_Hsap        ----RFLREAQSPEEPTPL------PVPLLLPPPST--PAP----------AA------P
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ------------------------------------------------------------


TNK1_Hsap       ------------------------------------------------------------
Ack_Dmel        YGQVPNGSGAVLYDEVTQDDYLRPTR-----------------------------PA---
PR2_Dmel        FKKVRASVNMAMNRKSVAETSLTSNQ-----------------------------PG---
ACK_Mmus        TATVRPMPQAAPDPK--ANFSTNNSN-----------------------------PG---
kin-25_Cele     VD-KKPVSQNQGSNV--PLFNITNSSNGYPQLNGYPNYGNGFQAYGYGMNYHQGYPGYQG
ark-1_Cele      T---------------------DQKP-----------------------------PP---
TNK1_Mmus       ------------------------------------------------------------
ACK_Hsap        TATVRPMPQAALDPK--ANFSTNNSN-----------------------------PG---
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ------------------------------------------------------------


TNK1_Hsap       --------------HNHPMGMP--------------------------------------
Ack_Dmel        -------------------PLAPPPLSAQQI----QRRMEKM----RLQQQQQ--L----
PR2_Dmel        -------------------GASAKPQTEAEYFAATAA---------RLADSNSVSCEDLL
ACK_Mmus        -------------------ARPPSLRATARL-----------------PQR-G--C----
kin-25_Cele     YNSYGNGMGQLALTHNAVTSLPPLVPSENRF-SGTAQPLGESDIMEFLGTQQR--Q----
ark-1_Cele      -------------------CRPPKT-----------------------------------
TNK1_Mmus       --------------HNHRTGAP--------------------------------------
ACK_Hsap        -------------------ARPPPPRATARL-----------------PQR-G--C----
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ------------------------------------------------------------


TNK1_Hsap       ---------GARKAAALSGGLLSDPELQRK--------------------IMEV-ELSVH
Ack_Dmel        DGAHQ-LYA--------PVP-SDYGREQEK--------------------LQQLMQELGS
PR2_Dmel        EF-----S-----DKKP-KG-CERGVDSDEVRIMVKVLGKDVSSLCTKNQISYN-QIFIS
ACK_Mmus        --------P--------GDG-QEAARPADK--------------------VQML-QAMVH
kin-25_Cele     AGSSSRAVPPASASTSAASG-ITDLSMADK--------------------MEVL-YREAD
ark-1_Cele      ------------------------------------------------------------
TNK1_Mmus       ---------GASKATVPSGGPLSDPEWQRK--------------------VVEV-ELSVH
ACK_Hsap        --------P--------GDG-PEAGRPADK--------------------IQML-QAMVH
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       ---------E------------TPNSAADK--------------------VKQV-QKEVH


TNK1_Hsap       GVTHQECQTALGATGGDVVSAIRNLKVDQLFHLSSR-SRAD-----CWRILEHYQWDLSA
Ack_Dmel        SAVEQDVRNALRAASGDVGLATRHYKIDQLARLGVA-GRPQ-----CEQALQQTNWSLEV
PR2_Dmel        QSTPNRCLGALEFINWDVHKSIKLIKLQNLVSEANL-SLEA-----SFEALQQHEWDLHT
ACK_Mmus        GVTTEECQAALQSHSWSVQRAAQYLKVEQLFGLGLR-PRVE-----CHKVLEMFDWNLEQ
kin-25_Cele     FTHKGNCDTMVSQCNGNTEQALKLLKQQHLVDMELAMSTET-----ARQALEARQYDLPA
ark-1_Cele      -------------RQFPLVIDERNLAYDNLNGFGAG-ARVAPPVPPKPKVRTIFSFADDQ
TNK1_Mmus       GVTYQECQVALRTTGGDVASAIRNLKVDQLFHLSNR-SRAD-----CRRILEHHQWDLSA
ACK_Hsap        GVTTEECQAALQCHGWSVQRAAQYLKVEQLFGLGLR-PRGE-----CHKVLEMFDWNLEQ
Ack1_Spur       ------------------------------------------------------------
Ack2_Spur       ------------------------------------------------------------
Ack3_Spur       GVTSDECRNALIGVQWDVTKAVRDLKTEQLFQLGSA-SKEH-----CENLLKSLEWNLEL


TNK1_Hsap       ASRYVLA-------RP
Ack_Dmel        AAELLLN-------AG
PR2_Dmel        TAHKLNG------LKL
ACK_Mmus        AGCHLLGSCGPAHHKR
kin-25_Cele     AANMLL---------G
ark-1_Cele      --KKQKE------VAN
TNK1_Mmus       ASRYILA-------RS
ACK_Hsap        AGCHLLGSWGPAHHKR
Ack1_Spur       -----SM------KCS
Ack2_Spur       ---------------W
Ack3_Spur       ASSIL----------L