BRDT_Mmus MSLPSRQT----------------------------------------------------
BRD4_Mmus MSTESGP-----------------------------------------------------
BRD3_Mmus MSTTAA------------------------------------------------------
BRD2_Mmus MLQNVTPHK-LP-GE-GNA--G-LLGLG--------------------------------
BRD2_Hsap MLQNVTPHNKLP-GE-GNA--G-LLGLG--------------------------------
BRD3_Hsap MSTATTV-----------------------------------------------------
BRD4_Hsap MSAESGP-----------------------------------------------------
BRDT_Hsap MSLPSRQT----------------------------------------------------
Y119C1B.8_Cele MSEGSGDQSQQR-PW---------------------------------------------
DDB0220693_Ddis MSLEQQDETVV-EEETKTSFETNNSTANNTNNNTDNTYKEEILKSTESIT--------RN
DDB0220694_Ddis MSNKTLPYCCE-HGL-KDEVIA-LLAKGEDVNQ-------------KDGS----------
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele MPTTRSA-----------------------------------------------------
F57C7.1b_Cele MSDYSAKPSGSLARI-G--DYD-LSSDDSDQND-------------EDETLIASKTIQTG
AqueK041_Aque MMEQNVSPPRLE-SRSS-SATP-MLNPGLVATQ---------------------------
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus ------------------------------------------------------------
BRD3_Mmus ------------AP----------------------------------------------
BRD2_Mmus --------PEAAAP----------------------------------------------
BRD2_Hsap --------PEAAAP----------------------------------------------
BRD3_Hsap ------------AP----------------------------------------------
BRD4_Hsap ------------------------------------------------------------
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele -----------ASPR------------------------------------Q--------
DDB0220693_Ddis --------DDKVDPTSATALE---------------------------------------
DDB0220694_Ddis ----------NRYPLHYAAIG---GYIEIVAML----------------LER--------
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele AVQVNDIAVAEASPAETD--------------A----------------KSS--------
AqueK041_Aque -----------ATPTTVPAMLVQSGN------VQNVSFQQQGGGGINSVPTNLTSYTSII
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus ------------------------------------------------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap ------------------------------------------------------------
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele ---------------QP-----IKGIVQP-------------------------------
DDB0220693_Ddis ---------------KD----I-INNGEYSGS------------------------SSSS
DDB0220694_Ddis ---------------GA----L-VNCSTPRGA------------------------TPLH
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele -----------------------NHPAPK-------------------------------
F57C7.1b_Cele ---------------AS----PVSGPEPPTSAVVENRDLDEFKKESGSNDDKQEEINEDK
AqueK041_Aque DPSQLLVKTEGVTSASPLSVGGANRTTPPTL-V----------------------TG---
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus -----------------------------------GTRLRNL------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus -----------------------------------GKRIRKP------------------
BRD2_Hsap -----------------------------------GKRIRKP------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap -----------------------------------GTRLRNL------------------
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis GN-------------------------------NNINGSNNIKNIV--------------
DDB0220694_Ddis YA-------------------------------SRGGRIECIQLLIDNKADVNCRD-GAG
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele DS-------------------------------NEETVFQQTESGSADVVDKTDVKQKDS
AqueK041_Aque -TGSITATPTAYTTAVTTSATSTTTVGGVTGGSILGKRIRRT------------------
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus -------------------------------------------------------PVMGD
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus -------------------------------------------------------SLLYE
BRD2_Hsap -------------------------------------------------------SLLYE
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap -------------------------------------------------------PVMGD
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis ---------IEKVEQ---------------------------------------------
DDB0220694_Ddis STPLHTALQCNETKCAIALIET---FGADV--NLKTAEGSTALHLASARGLVPVI-----
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele DSSADDDH-------------SHSKSGSVHSPQKPQGSTTPCSVQSPASPVGDEQAVKME
AqueK041_Aque -------------------------------------------------------STKYD
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus GLETSQMSTTQAQA--------------------------------------------QP
BRD3_Mmus ----------------------------------------------------------TG
BRD2_Mmus GFESPTM---------------------------------------------------AS
BRD2_Hsap GFESPTM---------------------------------------------------AS
BRD3_Hsap ----------------------------------------------------------AG
BRD4_Hsap GLETSQMSTTQAQA--------------------------------------------QP
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis -----------------------------------------------LERV----VVNNN
DDB0220694_Ddis --------------------------------------------VALLENG----ARADV
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele EVEEPIVASEEVPDKKPESVKESTDSESSGSEHGFEKMDTAEKVEDECNDDEVAASNGTE
AqueK041_Aque DFEQPLMRPSKVEA----------------------------------------------
BRDT_Mmus -----A-IVN------PP--------------PPEYI---N-TKKSGRLTN---------
BRD4_Mmus QPAN-AASTN------PP--------------PPETS---N-PNKPKRQTN---------
BRD3_Mmus IPAV-PGPVN------PP--------------PPEVS---N-PSKPGRKTN---------
BRD2_Mmus VPALQLAPAN------PP--------------PPEVS---N-PKKPGRVTN---------
BRD2_Hsap VPALQLTPAN------PP--------------PPEVS---N-PKKPGRVTN---------
BRD3_Hsap IPAT-PGPVN------PP--------------PPEVS---N-PSKPGRKTN---------
BRD4_Hsap QPAN-AASTN------PP--------------PPETS---N-PNKPKRQTN---------
BRDT_Hsap -----AIIVN------PP--------------PPEYI---N-TKKNGRLTN---------
Y119C1B.8_Cele ----------------------------------RVL---PPFGKPTRHTN---------
DDB0220693_Ddis NGDENNKDIHDSSNNTE---------------DIDI---------------------SKS
DDB0220694_Ddis RDSKENSPFQS-----L---------------PINLT---ENE-KKEKIENSISQDISKL
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele ----------------------------------RAI---SP-DSDDGE-----------
F57C7.1b_Cele EPEPGDKAADT-----VNPWETPRQEPVDGVVQPRTE---PPAGKPTRHTN---------
AqueK041_Aque KE---SSETRE-----KT--------------PSEKTTEEEGKGGGNRSTN---------
BRDT_Mmus -------------------------------------------------QLQFLQRVVLK
BRD4_Mmus -------------------------------------------------QLQYLLRVVLK
BRD3_Mmus -------------------------------------------------QLQYMQNVVVK
BRD2_Mmus -------------------------------------------------QLQYLHKVVMK
BRD2_Hsap -------------------------------------------------QLQYLHKVVMK
BRD3_Hsap -------------------------------------------------QLQYMQNVVVK
BRD4_Hsap -------------------------------------------------QLQYLLRVVLK
BRDT_Hsap -------------------------------------------------QLQYLQKVVLK
Y119C1B.8_Cele -------------------------------------------------KLDYIMTTVLK
DDB0220693_Ddis H-IIKYDKDEMSTIST-IHYSD-DESSKEKQ---------DNINSNNNNNKNKNE-----
DDB0220694_Ddis FNINKN-REFSGVGKKEDDDNNMKIDKQESEQQSTSDKLYSDITFLIENQKVYAHKCILQ
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele -------------------------------------------------CLDFVLFTVVK
AqueK041_Aque -------------------------------------------------QLQYLKN-VHR
BRDT_Mmus ALWKHGFSWPFQQPVDAVKLKLPDYYTIIKTPMD--------------------------
BRD4_Mmus TLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMD--------------------------
BRD3_Mmus TLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMD--------------------------
BRD2_Mmus ALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMD--------------------------
BRD2_Hsap ALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMD--------------------------
BRD3_Hsap TLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMD--------------------------
BRD4_Hsap TLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMD--------------------------
BRDT_Hsap DLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMD--------------------------
Y119C1B.8_Cele EAGKHKHVWPFQKPVDAVALCIPLYHERVARPMD--------------------------
DDB0220693_Ddis --------------------QIINSENILDTPMTEASDQTTPSDTPPTLTNNTSSTTTTT
DDB0220694_Ddis A-------------------RCPNFMSSINNKIE--------------------------
BRD_Spur ------------HPVDPTKLALPDYFKIIKTPMD--------------------------
F13C5.2_Cele ----------------------EDDFKSKRT-----------------------------
F57C7.1b_Cele DALKHKHSWPFQLPVDAIKLEIPEYHNIVNTPMD--------------------------
AqueK041_Aque IIWRHHYAWPFHKPVDPVALNIPDYFNIIKRPMD--------------------------
BRDT_Mmus ----------LNTIKKRLENKYY----------EKASECIEDFNTMF-------------
BRD4_Mmus ----------MGTIKKRLENNYY----------WNAQECIQDFNTMF-------------
BRD3_Mmus ----------MGTIKKRLENNYY----------WSASECMQDFNTMF-------------
BRD2_Mmus ----------MGTIKRRLENNYY----------WAASECMQDFNTMF-------------
BRD2_Hsap ----------MGTIKRRLENNYY----------WAASECMQDFNTMF-------------
BRD3_Hsap ----------MGTIKKRLENNYY----------WSASECMQDFNTMF-------------
BRD4_Hsap ----------MGTIKKRLENNYY----------WNAQECIQDFNTMF-------------
BRDT_Hsap ----------LNTIKKRLENKYY----------AKASECIEDFNTMF-------------
Y119C1B.8_Cele ----------LKTIENRLKSTYY----------TCAQECIDDIETVF-------------
DDB0220693_Ddis TTNNTTTAATTTTNSRRKRNSLS----------TPSSEMDPVLDSTS-------------
DDB0220694_Ddis ----------QQQSQKPIEIKDYSFKLFLSFIEWIYTGSIEKFESTSKSIDLSFQFSILL
BRD_Spur ----------LGTIKKRLESIYY----------HSAKECISDFNLMF-------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ----------LRTIEKRLRNLYY----------WCAEDAIKDLNTLF-------------
AqueK041_Aque ----------LTLIKKQLDHNGY----------SSAKECIQDFKTMF-------------
BRDT_Mmus ----------------------------------------SNCYL--------YNKTGDD
BRD4_Mmus ----------------------------------------TNCYI--------YNKPGDD
BRD3_Mmus ----------------------------------------TNCYI--------YNKPTDD
BRD2_Mmus ----------------------------------------TNCYI--------YNKPTDD
BRD2_Hsap ----------------------------------------TNCYI--------YNKPTDD
BRD3_Hsap ----------------------------------------TNCYI--------YNKPTDD
BRD4_Hsap ----------------------------------------TNCYI--------YNKPGDD
BRDT_Hsap ----------------------------------------SNCYL--------YNKPGDD
Y119C1B.8_Cele ----------------------------------------QNCYT--------FNGKEDD
DDB0220693_Ddis ----------------------------------------ENNTTRKTRGSRNSKKEPEE
DDB0220694_Ddis MGEKFDCKGLVSYCREFIKESIGDSNVGSIWSIIKKLPTSTRSNL--------GNLVRDC
BRD_Spur ----------------------------------------TNCYV--------YNKPGED
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ----------------------------------------DNCKK--------FNDRNDD
AqueK041_Aque ----------------------------------------NNCYT--------YNKPTDD
BRDT_Mmus IVVMAQALEK--------LFMQKLSQMPQEEQ-VVGG----------------K-ERIKK
BRD4_Mmus IVLMAEALEK--------LFLQKINELPTEET-EIMIVQA-------------K-GRGRG
BRD3_Mmus IVLMAQALEK--------IFLQKVAQMPQEEV-ELLPPAP-------------K-GKGRK
BRD2_Mmus IVLMAQTLEK--------IFLQKVASMPQEEQ-ELVVTIP-------------K-NSHKK
BRD2_Hsap IVLMAQTLEK--------IFLQKVASMPQEEQ-ELVVTIP-------------K-NSHKK
BRD3_Hsap IVLMAQALEK--------IFLQKVAQMPQEEV-ELLPPAP-------------K-GKGRK
BRD4_Hsap IVLMAEALEK--------LFLQKINELPTEET-EIMIVQA-------------K-GRGRG
BRDT_Hsap IVLMAQALEK--------LFMQKLSQMPQEEQ-VVGV----------------K-ERIKK
Y119C1B.8_Cele VTIMAQNVHE--------VIKKSLEQAPREEH-DMDVYWG-------------K-NKKK-
DDB0220693_Ddis LLLTPEQAKELSNKSKKWIYVPIIEAEAKKEE-VLPAKRDRKQVFNENIFSSSRKSTTKG
DDB0220694_Ddis LITMVRSWNIF--------TMTKTFSTDINKSDIIEIIKSLAPFI----TETPI-SEIKQ
BRD_Spur VVLMAQALEK--------LFLTKVAQMPQEEI-ELAPPVK--PGMGDDI-SGPG-RKGRK
F13C5.2_Cele ----------------------------------------------------PS-GRGRG
F57C7.1b_Cele IYIMCENIEG--------VVQRGLEWMPSEEK-PADLADHHRRGMFSA--STPS-GKTKG
AqueK041_Aque VVFMCQALER--------LFDQKVTGMPAEEF-EIVPGQ-----------------KGRK
:
BRDT_Mmus ----DIQ-QKI-----AVSSAKEQIP-SK-A-AEN-VFKRQ------EIPSGL-------
BRD4_Mmus ----R-K-ETGAAKPG-VSTVPNTTQ-AS-T-SPQTQTPQQ------NPPPPVQATT---
BRD3_Mmus ----P---AAGAQNAG----SQQVAA-VS-S-VSP-ATPFQ------NIPPTVSQTPVIA
BRD2_Mmus ----G---AKLAALQGSITSAHQVPA-VS-S-VSH--TALY------TPPPEIPTTV--L
BRD2_Hsap ----G---AKLAALQGSVTSAHQVPA-VS-S-VSH--TALY------TPPPEIPTTV--L
BRD3_Hsap ----P---AAGAQSAG----TQQVAA-VS-S-VSP-ATPFQ------SVPPTVSQTPVIA
BRD4_Hsap ----R-K-ETGTAKPG-VSTVPNTTQ-AS-T-PPQTQTPQP------NP-PPVQATP---
BRDT_Hsap ----GTQ-QNI-----AVSSAKEKSS-PS-A-TEK-VFKQQ------EIPSVF-------
Y119C1B.8_Cele ----PAK-SDGGSKS---SSSKK----ND-A-RGPSEAPSEAGSEVS-------------
DDB0220693_Ddis GEKKNDTASTTNTPI---ITAQQNTTPLSPTQTTTTTTTPTTTTAQQ-------------
DDB0220694_Ddis TRTANANASNSNQSK---TPAKR----TSTT-NTNNNIPQQNITSSN-------------
BRD_Spur GRVPGRG-ISANSRLG-IQNASP----QP-S------VPNAATTQ-LPGPPAKNAYVAPL
F13C5.2_Cele GRGRGRG-RGRGGAT---AA-------GATV-EGGES--------TR-------------
F57C7.1b_Cele PKQRGRK-STRGRKK---TSLPR----GAST-FKDESVDDNNDDESS-------------
AqueK041_Aque ---PGPK-SNAGRRT---KMAAA----ES-T------VNLDSPGD---------------
BRDT_Mmus ----PDI----S-----------------------------------LSPLN--------
BRD4_Mmus -HPFPAVTPDLIAQPPVMTMVPPQPLQTPS----------PV-PPQPPPPPA--------
BRD3_Mmus ATPVPTITANVT--------------S--V----------PV-PPPAAPPP---------
BRD2_Mmus NIPHPSVISSPL--------------L--K----------S--LHSAGPPL---------
BRD2_Hsap NIPHPSVISSPL--------------L--K----------S--LHSAGPPL---------
BRD3_Hsap ATPVPTITANVT--------------S--V----------PV-PPAAAPPP---------
BRD4_Hsap -HPFPAVTPDLIVQTPVMTVVPPQPLQTPP----------PV-PPQPQPPPA--------
BRDT_Hsap ----PKT----S-----------------------------------ISPLN--------
Y119C1B.8_Cele SVTT---------------------------------------ASA-AAPTVSE------
DDB0220693_Ddis NTPAQTESKPP----TTISINIKGS-KSPKTTGGKQQKPTPPSPVVISQPVVPSTPVVAT
DDB0220694_Ddis NTPQ---------------------------------------QNT------SSSSSSST
BRD_Spur AMKSPTATQPS----TELPVLPPGAASTQA----------TA-AAMSTSPLVSS------
F13C5.2_Cele GG--------------------------------------------------------GT
F57C7.1b_Cele KVDS---------------------------------------IN-F-----DDDDDTAT
AqueK041_Aque -------------------------VSLVS----------ST-SSTVQPPLV--------
BRDT_Mmus -----------------------------------M--A---------------------
BRD4_Mmus --------------------PVP-----------QP--V---------------------
BRD3_Mmus -----------------------------------P--A---------------------
BRD2_Mmus -----------------------------------L--A---------------------
BRD2_Hsap -----------------------------------L--A---------------------
BRD3_Hsap -----------------------------------P--A---------------------
BRD4_Hsap --------------------PAP-----------QP--V---------------------
BRDT_Hsap -----------------------------------V--V---------------------
Y119C1B.8_Cele ----------------------SASVA---------------------------------
DDB0220693_Ddis TKKTNSRSKRSTANNNSETTQTPEVVISAPTTTTAAITTPINITPSSDSATIQQLQQSIS
DDB0220694_Ddis TS----------------------------------------------------------
BRD_Spur --------------------PPPISTP------VEP--VKQNS-----------------
F13C5.2_Cele -----GRGGR--------------------------------------------------
F57C7.1b_Cele EKDAESRAES----------VQPEVVN---------------------------------
AqueK041_Aque --------------------PAPLSTT---------------------------------
BRDT_Mmus -------------------------------------------------------QEAPP
BRD4_Mmus -------------------------------------------------------QSHPP
BRD3_Mmus -------------------------------------------------------TPIVP
BRD2_Mmus ----------------------------------------------------------VS
BRD2_Hsap ----------------------------------------------------------VT
BRD3_Hsap -------------------------------------------------------TPIVP
BRD4_Hsap -------------------------------------------------------QSHPP
BRDT_Hsap -------------------------------------------------------QGASV
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis MLEDKIRLISSNNKVATEILNNTITTTTTTAATSAIKDEEIIENTELQTTFTKSSTLAPP
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur -------------------------------------------------------LPGPP
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus ------------------------------I-CDSQSLVQITK--GVKRRADTTTPTTSI
BRD4_Mmus ------------------------------IIATTPQPVKTKK--GVKRKADTTTPTTID
BRD3_Mmus ------------------------------VV-PPTPPVVKKK--GVKRKADTTTPTTSA
BRD2_Mmus ------------------------------AA-PPAQPLAKKK--GVKRKADTTTPTPTA
BRD2_Hsap ------------------------------AA-PPAQPLAKKK--GVKRKADTTTPTPTA
BRD3_Hsap ------------------------------VV-PPTPPVVKKK--GVKRKADTTTPTTSA
BRD4_Hsap ------------------------------IIAATPQPVKTKK--GVKRKADTTTPTTID
BRDT_Hsap ------------------------------N-SSSQTAAQVTK--GVKRKADTTTPATSA
Y119C1B.8_Cele --------------------------------AKPERKVAGKK--TGKRKAESEDDEK--
DDB0220693_Ddis SSERKYSNLYSDDEDDTEMVDVSVSIPIPIPIPTPTQTTTKKTTLSKKRKSNTSTIIPTT
DDB0220694_Ddis ---------------------------------------------STPSKSSSSTPSKST
BRD_Spur ------------------------------KVRS-PAKTKGAR--GVKRKADTTTPTTVI
F13C5.2_Cele ---------------------------------------------GRPRGSKN-------
F57C7.1b_Cele --------------------------------EEPKPSTSQPP--SKKRKAENGEPAVAV
AqueK041_Aque -----------------------------------TQPVIKRK--GVKRQADTTTPHSGQ
:..
BRDT_Mmus AKA-SS------ESPPT---L-----RETKPVNM-PVKENT------VKNVLPDSQ----
BRD4_Mmus PIHE---------PPSL---A-----PEPKTAKLGPRR-ESSRPVKPPKKDVPDSQ----
BRD3_Mmus ITASRS------ESPPP---L-----SEPKQAKVVARRESGGRPIKPPKKDLEDGE----
BRD2_Mmus ILAPGS--P---ASPPG---S-----LEPKAARLPPMRRESGRPIKPPRKDLPDSQ----
BRD2_Hsap ILAPGS--P---ASPPG---S-----LEPKAARLPPMRRESGRPIKPPRKDLPDSQ----
BRD3_Hsap ITASRS------ESPPP---L-----SDPKQAKVVARRESGGRPIKPPKKDLEDGE----
BRD4_Hsap PIHE---------PPSL---P-----PEPKTTKLGQRR-ESSRPVKPPKKDVPDSQ----
BRDT_Hsap VKA-SS------EFSPT---F-----TE-KSVALPPIKENM------PKNVLPDSQ----
Y119C1B.8_Cele --------------PEPLR---A------KRE-----V-------AVVKKEV--------
DDB0220693_Ddis TIQQEQGQEQGQQQPPQQQ---Q-P----PQQ-----Q-------QPPQQQQPPQQQPPQ
DDB0220694_Ddis STSSSS------SSSSS-------------------------------------SSSS--
BRD_Spur EP-PE---P-I-VAPSADYHL-----AQAKPAKIPGRRESSRRNIKPPNRELPESD----
F13C5.2_Cele SD-GG------------AG---G-P----PA------K--------RGRKKKAKSE----
F57C7.1b_Cele KI-ATP------ATP--VA---A-H----PQ------E-------ETPRRKNPNTLIE--
AqueK041_Aque PS-PTSGVP-L-DQPPPPAVVVASTPVHILSSAVPTRRES-TRTIKRPKLDLPGES----
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus ------------------------------------------------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap ------------------------------------------------------------
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis QSTSPSKTQQENTSSTTTTTTTTTTTTNTEDTTTVIDKKPKKKPRHSAPLIPQIKPRLPL
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur ------------------------------------------------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele --------W---------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus ------QQHK--------VLKTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDADAL
BRD4_Mmus ------QHPG--------PEKSSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEAL
BRD3_Mmus ------VPQH--------AGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEAL
BRD2_Mmus ------QQHQ--------SSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASAL
BRD2_Hsap ------QQHQ--------SSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASAL
BRD3_Hsap ------VPQH--------AGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEAL
BRD4_Hsap ------QHPA--------PEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEAL
BRDT_Hsap ------QQYN--------VVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNAL
Y119C1B.8_Cele ---------------------HQPLLPSMKPCLKLLNDFSTKKYQEFAWPFNEPVDAEQL
DDB0220693_Ddis NGGSSERAQRSSRGRMGKAMRDVVLTPVFKRCLDLLEELFEHQHS---PPFLVAVDPYAL
DDB0220694_Ddis -------SSS--------NYSDSMNEKNLTFCKGLINGMFKKKTS---LAFQRPVDPLAE
BRD_Spur ------QHQK---------GKKGKLTAQLKYCYGVIKELMSKKHSAYAWPFFKPVDADVL
F13C5.2_Cele ------SEDE---------AESDHLHDELKKCLSILKEFEKSTHDSFTFPFRKPVDVVLL
F57C7.1b_Cele ------KHLV--------PRWQGKIPEWQKFCSKLLNEIHSVKNKGFAQVFYLPVDPIKL
AqueK041_Aque --------SY---------GRKRPLTVQLRYCLSIVKDFFSKKHQASAWPFYNPVDVKGL
* ::. : * .**
BRDT_Mmus GLHNYYDVVKNPMDLGTIKGKMDNQEYKDAYEFAADVRLMFMNCYKYNPPDHEVVAMART
BRD4_Mmus GLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK
BRD3_Mmus ELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARK
BRD2_Mmus GLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARK
BRD2_Hsap GLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARK
BRD3_Hsap ELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARK
BRD4_Hsap GLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARK
BRDT_Hsap GLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARM
Y119C1B.8_Cele GLHDYHKIIKEPMDLKSMKAKMESGAYKEPSDFEHDVRLMLRNCFLYNPVGDPVHSFGLR
DDB0220693_Ddis GILDYFDVIKHPMDLGTIKASLIGGGYDTIDKFAEDCRLVFSNAKTYNPSTNPVHIMAQS
DDB0220694_Ddis GIPDYFDVIKHPMDLGTIKGKLDNNGYSTIKDFAADVRLMFENALTYNADSSPVWKHAKT
BRD_Spur GLHDYHEIIKTPMDMGTVKVKLENRDYKNANDFAANVRLIFTNCYKYNPPDHDVVGMARK
F13C5.2_Cele GLTDYHEVIKKPMDMSTIRKKLIGEEYDTAVEFKEDFKLMINNCLTYNNEGDPVADFALQ
F57C7.1b_Cele KIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALE
AqueK041_Aque GLHDYLDIIKQPMDLTTLKKKLEDREYEDPSQFAADMRLIFTNCYKYNPPEHDVVKMARK
: :* .::. ***: ::: .: * * : .*:. *. ** . .
BRDT_Mmus LQDVFELHFAKI-PDEPIE--SMHACHLTT------NSAQALSRESSSEASSG-------
BRD4_Mmus LQDVFEMRFAKM-PDEPEE--PVVTVSSPAVPPPTKVVAPPSSSDSSSDSSSDS------
BRD3_Mmus LQDVFEMRFAKM-PDEPME--APALPAPTA-P----IVSKGAESSRSSEESSSD------
BRD2_Mmus LQDVFEFRYAKM-PDEPLE--PGPLPVSTALP----PGLTKSSSESSSEESSSESSSEEE
BRD2_Hsap LQDVFEFRYAKM-PDEPLE--PGPLPVSTAMP----PGLAKSSSESSSEESSSESSSEEE
BRD3_Hsap LQDVFEMRFAKM-PDEPVE--APALPAPAA-P----MVSKGAESSRSSEESSSD------
BRD4_Hsap LQDVFEMRFAKM-PDEPEE--PVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDS------
BRDT_Hsap LQDVFETHFSKI-PIEPVE--SMPLCYIKT------DITETTGRENTNEASSE-------
Y119C1B.8_Cele FQEVFDRRWAEL-GDSSSR--ASSVAPQSAPIAPTPK-VAKSSAPKEPKESRKEHKKE--
DDB0220693_Ddis LEDVFEKGFPK-VLIEPPS--PPPKNVD------QE--KIE--K-LSN-----DL-----
DDB0220694_Ddis LLNAFDQKFLQNFPNEKPPTYKPPPPTP------TP--IPT--Q-QQQQQSTSST-----
BRD_Spur LQNVFEVKFAKM-PDEPLD--PSDLESDD-E-SK-D--ETKAMD-SPSDASASNS-----
F13C5.2_Cele FRKKFAAKWKKEFPEDG--------------------------D-SFGQEKGEKE-----
F57C7.1b_Cele LRSFFEQRWKLF-PRPGVD--PIIADSY--I--NQN--LVVNTD-LIEDERINSY-----
AqueK041_Aque VQDIFEFKFARM-PEEPPP--APPKKTS--I-KM-K--TGGSSD-SSSSESEDND-----
. . * :
BRDT_Mmus -----------DASSEDSEDERVQHLAK--LQEQ-----------------LNAVHQQLQ
BRD4_Mmus -----------DSSTDDSEEERAQRLAE--LQEQ-----------------LKAVHEQLA
BRD3_Mmus ------------SGSSDSEEERATRLAE--LQEQTGCGAFQDQLLNVSSVQLKAVHEQLA
BRD2_Mmus EEE-EEDEDEEESESSDSEEERAHRLAE--LQEQ-----------------LRAVHEQLA
BRD2_Hsap EEEDEEDEEEEESESSDSEEERAHRLAE--LQEQ-----------------LRAVHEQLA
BRD3_Hsap ------------SGSSDSEEERATRLAE--LQEQ-----------------LKAVHEQLA
BRD4_Hsap -----------DSSTDDSEEERAQRLAE--LQEQ-----------------LKAVHEQLA
BRDT_Hsap -----------GNSSDDSEDERVKRLAK--LQEQ-----------------LKAVHQQLQ
Y119C1B.8_Cele ----------TTFEASGAKS---EDLMQ--INNA-----------------LSMIREREE
DDB0220693_Ddis ----------------------------------------------------KNVTKELE
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur -----------SSESEDSEEEREKRLSE--LQEQ-----------------LKAVHEQLA
F13C5.2_Cele -----------GSD-NEDDE---EEVDEKEKEEE-----------------V--------
F57C7.1b_Cele -----------LSA-VKAEE---KKCAE--KLEQ-----------------LRSMSEGLY
AqueK041_Aque -----------SSEESDSESERASQLSK--LQEQ-----------------VIMVSKQLA
BRDT_Mmus VLSQV----------------PLRKLKKK--------NE-KSK-----------------
BRD4_Mmus ALSQP----------------QQNKPKKK---------E-KDK-----------------
BRD3_Mmus ALSQA----------------PVNKPKKK--------KE-KKE-----------------
BRD2_Mmus ALSQG----------------PISKPKRK--------RE-KKE-----------------
BRD2_Hsap ALSQG----------------PISKPKRK--------RE-KKE-----------------
BRD3_Hsap ALSQA----------------PVNKPKKK--------KE-KKE-----------------
BRD4_Hsap ALSQP----------------QQNKPKKK---------E-KDK-----------------
BRDT_Hsap VLSQV----------------PFRKLNKK--------KE-KSK-----------------
Y119C1B.8_Cele KLKAE----------------LAAA--------QAI-KDKLTS-----------------
DDB0220693_Ddis KFKKD----------------DSNSINNNN------------------------------
DDB0220694_Ddis ---ST----------------PTS-EKKRK------------------------------
BRD_Spur ALSSQ----------------AHRKKKKK--------DK-DKT-----------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele TIAMQ----------------RR-EAKLAGNTAPALAQNQLSQLEGLGISIKSTPMMIPE
AqueK041_Aque ALSKKGGGGGTPTLGIDANFAPFLSPAPS--------KE-KKK-----------------
BRDT_Mmus -------------RAP--KRKKVN------------------N-----------------
BRD4_Mmus -------------KEK--KK---E--------K-HK------K-----------------
BRD3_Mmus -------------KEK--KKKDKDKDKE----K-EK------H-----------------
BRD2_Mmus -------------KKK--KRKA-E--------K-HR------G-----------------
BRD2_Hsap -------------KKK--KRKA-E--------K-HR------G-----------------
BRD3_Hsap -------------KEK--KKKDKEK--E----K-EK------H-----------------
BRD4_Hsap -------------KEK--KK---E--------K-HK------R-----------------
BRDT_Hsap -------------KEK--KKEKVN------------------N-----------------
Y119C1B.8_Cele -------------VKN--RRED-NPNEPFPEK------LI--------------------
DDB0220693_Ddis --------NNNNNYNN--NNNN-NNNNS----SSSSS-RS--------------------
DDB0220694_Ddis ---------HDEHVKV--KEDT-NSAQPTSSSSNHTN-GE--------------------
BRD_Spur -------------KKK--ERKDIEKEKE----ELEKAKELERQREKEMEEMREKERKLLE
F13C5.2_Cele ------------------KEDN-AEEKPAEEP----------------------------
F57C7.1b_Cele LISPALSVRSSSRAPVPKIIDD-IGPSPIKAR------KI--------------------
AqueK041_Aque -------------KKD--KSSRKGKNKP-----VPS------------------------
BRDT_Mmus -RDE---N-------PRKK----P--KQMKQKEKA--K-------------------IN-
BRD4_Mmus -KEEVEEN----KKSKTKEL---P----PKKTKKNNSSNSN--------------VSKK-
BRD3_Mmus -KAKSEEE----KKAKAAPA---A--KQAQ-QKKAPTKKANST-----------TTASR-
BRD2_Mmus -RIGIDED----DKGPRAPR---P--PQPKKSKKAGGGGSNATTLSHPGFGTSGGSSNK-
BRD2_Hsap -RAGADED----DKGPRAPR---P--PQPKKSKKASGSGGGSAALGPSGFGPSGGSGTK-
BRD3_Hsap -KVKAEEE----KKAKVAPP---A--KQAQ-QKKAPAKKANST-----------TTAGR-
BRD4_Hsap -KEEVEEN----KKSKAKEP---P----PKKTKKNNSSNSN--------------VSKK-
BRDT_Hsap -SNE---N-------PRKM----C--EQMRLKEKS--K-------------------RN-
Y119C1B.8_Cele --------NETRA--L--CTT---------QVGQNAS-SSS-------------ASSAAL
DDB0220693_Ddis -----SS-RKSHSSGS--SSSHR--SGSSRS-SRGS--SSS--------------SS---
DDB0220694_Ddis -----NA-SSSS----------S--SSSSKQSNNNNN-NNN--------------NN---
BRD_Spur EKARDEERSKSASKRPRKPAKSTEDKAKPKKTNRPRK-NAK-------------TAEEKP
F13C5.2_Cele ----------------------------------------E-------------QPDEKE
F57C7.1b_Cele --------SKPRA--S--MASNV--SVPY-------T-PTG-------------NPRGRK
AqueK041_Aque ------------TSTPLLPT------LQPKKSKSA-------------------------
BRDT_Mmus QP----------KKK-------KPLLKSEEEDN--------------AKPMNYDE-KRQL
BRD4_Mmus EPV--------PTKTK-----PPPTYESEEEDK--------------CKPMSYEE-KRQL
BRD3_Mmus QLK--------KGGKQ-----ASASYDSEEEEE--------------GLPMSYDE-KRQL
BRD2_Mmus LPK--------KSQKT-APPVLPTGYDSEEEEE--------------SRPMSYDE-KRQL
BRD2_Hsap LPK--------KATKT-APPALPTGYDSEEEEE--------------SRPMSYDE-KRQL
BRD3_Hsap QLK--------KGGKQ-----ASASYDSEEEEE--------------GLPMSYDE-KRQL
BRD4_Hsap EPA--------PMKSK-----PPPTYESEEEDK--------------CKPMSYEE-KRQL
BRDT_Hsap QP----------KKRK-Q---QFIGLKSEDEDN--------------AKPMNYDE-KRQL
Y119C1B.8_Cele RNG--------RSKKAASARLYGYEFDSDDEDN--------------KMALTYEE-KRNL
DDB0220693_Ddis --S--------SSSSSS-SSSSSSSSSSSNNKK--------------YPKVTTEE-KTKL
DDB0220694_Ddis --N--------SN---S-TTNSSS-SSSSTTTT--------------QKKYSDEE-RRSL
BRD_Spur KPKRTNSRRGGGRKKK-V--PTTGQLESDDEDT--------------AKPMSYDE-KRQL
F13C5.2_Cele -EE--------DH--ED-EREEQEEEDSSDEEDGL----------------DDDDVRR--
F57C7.1b_Cele -PK--------KSGRPK-KNIYSPATVSERISQQPPFEVTPYVSIYGRKVVGTND-KIEL
AqueK041_Aque -------------KKR-T--PLNW-QPSSDEED--------------VKPMTYDE-KRQL
*. :: :
BRDT_Mmus SLDINKLPGDKLGRIVHIIQSREPSL-----RNSNPDEIEIDFETLKASTLRELEKYVLA
BRD4_Mmus SLDINKLPGEKLGRVVHIIQSREPSL-----KNSNPDEIEIDFETLKPSTLRELERYVTS
BRD3_Mmus SLDINRLPGEKLGRVVHIIQSREPSL-----RDSNPDEIEIDFETLKPTTLRELERYVKS
BRD2_Mmus SLDINKLPGEKLGRVVHIIQAREPSL-----RDSNPEEIEIDFETLKPSTLRELERYVLS
BRD2_Hsap SLDINKLPGEKLGRVVHIIQAREPSL-----RDSNPEEIEIDFETLKPSTLRELERYVLS
BRD3_Hsap SLDINRLPGEKLGRVVHIIQSREPSL-----RDSNPDEIEIDFETLKPTTLRELERYVKS
BRD4_Hsap SLDINKLPGEKLGRVVHIIQSREPSL-----KNSNPDEIEIDFETLKPSTLRELERYVTS
BRDT_Hsap SLNINKLPGDKLGRVVHIIQSREPSL-----SNSNPDEIEIDFETLKASTLRELEKYVSA
Y119C1B.8_Cele SNLINNLPNNQLNTIISIIQRRERSA--LMQQQLDDSEVELDFESLGDMCLREMGAFIKT
DDB0220693_Ddis GAEITQLPVDLLPSILQIIHNTN-S----LPEQKPGSEVVIDLMKFDDDILRRLSKFVEQ
DDB0220694_Ddis MERINELAPDDVQEVLNIIDP---N----AIKQA-DESLEIDMYQIDDKNLSQVESFINE
BRD_Spur SLDINKLPGDKLGKVVHIIQSREPSL-----KDSTPDEIEIDFETLKPSTLRELEKYVMQ
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele SERMASIPQMYITPILRIIQIGHHNTGKTITSLRSLCEEEIDFNDVSDDLVIELLDYLEM
AqueK041_Aque SLDINKLPGVTLNRVVHIIQMRERTI-----KDGNPDEIEIDFETLKPATLRELEKYVNS
BRDT_Mmus CLRKR----SLKPQAK--K--V--------------------------VRSKEELHSEKK
BRD4_Mmus CLRKK----R-KPQAEK--VDVIAGSSKMKGFSSSESESTSESSSSDSEDSETEMAPKSK
BRD3_Mmus CLQKK----QRKPLSTSGKKQA--------------------------AKSKEELAQEKK
BRD2_Mmus CLRKK----PRKPYTI--RKPV--------------------------GKTKEELALEKK
BRD2_Hsap CLRKK----PRKPYTI--KKPV--------------------------GKTKEELALEKK
BRD3_Hsap CLQKK----QRKPFSASGKKQA--------------------------AKSKEELAQEKK
BRD4_Hsap CLRKK----R-KPQAEK--VDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSK
BRDT_Hsap CLRKR----PLKPPAK--K--I--------------------------MMSKEELHSQKK
Y119C1B.8_Cele IPTLNGNGDDEKPKTS--SNPTSSGA----------------------TGSKGSSSLESK
DDB0220693_Ddis YKNGEI-PQHALPLSA----PSSTHS----------------------SHSSSHDSSSNI
DDB0220694_Ddis CFKK--------------------------------------------------------
BRD_Spur CLRKR-----PKAYNK--GQ----------------------------TKSKQDAQKEKQ
F13C5.2_Cele ----------HIPA-------------------------------------------STS
F57C7.1b_Cele IQKDK-----AKAE-------------------------------------------QVR
AqueK041_Aque VLKKQ-----KRPPTN--KS---------------------------------MDAAKKR
BRDT_Mmus LEL-ERRLL---DVN-NQLN----CRK-----RQT-KRPAKVEKPPPPPPPPPPPPPPPE
BRD4_Mmus KKGHTGRDQ---KKH-H-HHHHPQMQP-----APA-PV--PQQPP---------------
BRD3_Mmus KEL-EKRLQ---DVS-GQLN----S-K-----KPT-KK--E--KS---------------
BRD2_Mmus REL-EKRLQ---DVS-GQLN----STK-----KPP-KK--ASEKT---------------
BRD2_Hsap REL-EKRLQ---DVS-GQLN----STK-----KPP-KK--ANEKT---------------
BRD3_Hsap KEL-EKRLQ---DVS-GQLS----SSK-----KPA-RK--E--KP---------------
BRD4_Hsap KKGHPGREQ---KKH-H-HHHHQQMQQ-----APA-PV--PQQPP---------------
BRDT_Hsap QEL-EKRLL---DVN-NQLN----SRK-----RQT-KS----DKT---------------
Y119C1B.8_Cele NGK-K---KK--------------------------------------------------
DDB0220693_Ddis REI-EKLQKQLDRLGKGQQN----SSSSSSSSSHSKRI--SKPIS---------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur KEL-EDRLK---ELG-GPFP------K-----KAT-KK----AQQ---------------
F13C5.2_Cele APV-AKH--------------------------PEA------------------------
F57C7.1b_Cele QEL-EVKAKFYG----FEAY----DNKL-GTIPKTR------------------------
AqueK041_Aque AEL-EKRLQ---DVS-GKLG----GGSG--MPKLP-KT--KKSKS---------------
BRDT_Mmus LASGSRLTDSSSSS----------------------------------------------
BRD4_Mmus ------------------------------------------------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap ------------------------------------------------------------
BRDT_Hsap --------QPSKAV----------------------------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis --------KARGRKVISTSSSNLNNSSNNINNNNNNINNYNNNNNYNNNNNNNLNNNNNN
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur --------DALMNE----------------------------------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque --------DAKGSK----------------------------------------------
BRDT_Mmus -----------------------------------GSGSG--SSSSS-SGSSSSSSSS--
BRD4_Mmus ------------------------------------------------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap ------------------------------------------------------------
BRDT_Hsap -----------------------------------ENV----SRLSE-S-SSSSSSSS--
Y119C1B.8_Cele --------------------------------------NFNMSESSDDE-TSNSRKRRKR
DDB0220693_Ddis NINSNLNNNLNNNNNKDDIVIDGFKKENFSSIPEKDV-ETDISESS----DSESDSES--
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur -----------------------------------GG-RT--ERPLS-A-SSSSDSES--
F13C5.2_Cele ------------------------------AMPE--------------------------
F57C7.1b_Cele ------------------------------NMPP-PL-QHRMRSDS----PSPSASRT--
AqueK041_Aque -----------------------------------DL-KS--SRLSD-S-SSSSDDDSAN
BRDT_Mmus GSASSS-SDSSSSDSSDSEPEIFPKFTGVK-Q---N------------------------
BRD4_Mmus ------------------------PPPQ--------------------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap ------------------------PPPQ--------------------------------
BRDT_Hsap ESESSS-SDLSSSDSSDSESEMFPKFTEVK-P---N------------------------
Y119C1B.8_Cele ESSES-QSSSSSDDDSDDED--RPSIPR--------------------------------
DDB0220693_Ddis GSSDS-SSSYSDSDFSDSDNDRRRNYNNSY-NNNNNNNNNNNSSNNFNNQNNSYNNSNNN
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur DASSST-SASSSSDNSESESGT-PKKMKKGIKVP-PLP----------------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele GNQSS-DSDSASDDSSDDEPS--RSNS---------------------------------
AqueK041_Aque EEESSSGTGSSTSSSSDEEKDVKPVQKART-----P------------------------
BRDT_Mmus -------------------------------------------------DLPPKENIKQ-
BRD4_Mmus -------------------------------------------------QPPPPPPPQQQ
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap -------------------------------------------------QPPPPPPPQQ-
BRDT_Hsap -------------------------------------------------DSPSKENVKKM
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis NNNNSSNNNNNNNNNNSNNNNSNNNNNNVNNN----------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur -------------------------------ANRQEMQRRLSGPGQAPITTPAGFHPETQ
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus QQQPPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEPQLPGSVFDPIGHFT-QPILHLP
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap QQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFT-QPILHLP
BRDT_Hsap KNECIPPEGRTGV-T---------------------------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis ------------------------------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur QQQPMSTGPGPS-PFS-------------------LGPQA---TGHPSGHPSGQPVQHPG
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus ---------------------------IQSSVQ-----------DITSAEAP--------
BRD4_Mmus QPELPPHLPQPPEHSTPPHLNQHAVVSPPA---LHNALPQQPSRPSNRAAALPPKPTRPP
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap QPELPPHLPQPPEHSTPPHLNQHAVVSPPA---LHNALPQQPSRPSNRAAALPPKPARPP
BRDT_Hsap --------------------------QIGYCVQ-----------DTTSANTT--------
Y119C1B.8_Cele ----------------------------------KSGQPPSTSR----------------
DDB0220693_Ddis ----------NNNHNNNNHNNN--INNNNNNINNNTTQPSPSQQ----ST----------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur QPS--PRLTNGQNHIPAP---------------RHSSLPALPDRPSNKAAPLQKRSQRKV
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele -----------------------------------NVAG---------------------
AqueK041_Aque ---------------------------------QATSKPIAPAYQTTSAASIIGRSQSK-
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus --------------------------AVSPALAQP-PLLPQPPMAQPPQVLLEDEEPPAP
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap --------------------------AVSPALTQT-PLLPQPPMAQPPQVLLEDEEPPAP
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis ------------------------------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur LTSPLTSPGPLTSPANTRGSTTTAFPLPSPTLPQTKPAVVAPPQLQPPAVS---KAPPAT
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus -------------------------------LAQQSTA-PCGAPG---------------
BRD4_Mmus PLT-----SMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQPQPP
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap PLT-----SMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQ-QLQQQPP
BRDT_Hsap -------------------------------LVHQTTP-SHVMPP---------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis ------------------------------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur PPAMAPSAPVAPQPAPVAIPKPKPEPVVKPSKPAPSQTPPAAVPPP--SSTK--------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus -----------------------------------------------------K------
BRD4_Mmus PPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQ--QPPPPP-GQQPTHPPPGQQPPPPQ
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap PPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQ--QPPPPQ-GQQPPHPPPGQQPPPPQ
BRDT_Hsap -----------------------------------------------------N------
Y119C1B.8_Cele ------------------------------EWNQSSAPPPRM-GGMGG------------
DDB0220693_Ddis ------------------------------SLTNEPIKPPTILQTVKK--PAL--PVTG-
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur ----PLPQHPPPQQHPSRHSPQPLPQQQATSKPQSKPPPPTD--IPKPQPPAAQRPIPAD
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus ------------------------------------------------------------
BRD4_Mmus PAK-----PQQVIQHHPSPR-------------------------------------HHK
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap PAK-----PQQVIQHHHSPR-------------------------------------HHK
BRDT_Hsap ------------------------------------------------------------
Y119C1B.8_Cele -----------QP-----------------------------------------------
DDB0220693_Ddis ----------SVASWSFD------------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur --TKKTAPPRSVTPPSPPPQVKPEVPSLIQQPTLIPKVEDNPMSFMVGDEDLEGEGESPS
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus ------------------------------HSQQMLGCQVTQHLQAT-E-----------
BRD4_Mmus SDPYSAGHLREAPSP------------LMIHSPQMPQFQSLTHQSPPQQNVQPKKQVKGR
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap SDPYSTGHLREAPSP------------LMIHSPQMSQFQSLTHQSPPQQNVQPKK-----
BRDT_Hsap ------------------------------HHQLAFNYQELEHLQTV-K-----------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis ------------------------------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur TSPVMTGHKTEESNGSSHPEGGMPSSASSENLSKMEQKASSKDKKPPAVSKAPPATP---
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus --------------------------------NTA-------------------------
BRD4_Mmus AEPQPPGPVMGQGQGCPPASPAAVPMLSQELRPPSVVQPQPLVVVKEEKIHSPIIRSEPF
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap ----------------------------QELRAASVVQPQPLVVVKEEKIHSPIIRSEPF
BRDT_Hsap --------------------------------NIS-------------------------
Y119C1B.8_Cele ------------------------------------------------------------
DDB0220693_Ddis ------------------------------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur ----------------------------PAMAPSAPVAPQPAPVAIPKPKPEPVVKPSKP
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque ------------------------------------------------------------
BRDT_Mmus ---------------------------------------SVQTQPLSG------------
BRD4_Mmus STSLR-----------------PEPPKHPENIKAPVHLP---------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap SPSLR-----------------PEPPKHPESIKAPVHLP---------------------
BRDT_Hsap ---------------------------------------PLQILPPSG------------
Y119C1B.8_Cele ---------------------------------------PMSRVPASS------------
DDB0220693_Ddis ---------------------------------------PTNNKESSS------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur APSQTPPAAVPPPSSTKPLPQHPPPQQHP-SRHSPQPLPQQQATSKPQSKPPPPTDIPKP
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ---------------------------------------PRRALELSG------------
AqueK041_Aque --------------------------------------SSLTTVPAGGAVAPPPTK----
BRDT_Mmus -----------DCK----------------------------------------------
BRD4_Mmus --------QRPEMK----------------------------------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap --------QRPEMK----------------------------------------------
BRDT_Hsap -----------DSE----------------------------------------------
Y119C1B.8_Cele -----------STSVS--------------------------------------------
DDB0220693_Ddis -----------SSSTS--------------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur QPPAAQRPIPADTKKTAPPRSVTPPSPPPQVKPEVPSLIQQPTLIPKVEDNPMSFMVGDE
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele -----------NSSSA--------------------------------------------
AqueK041_Aque --------------------DAAPPSP---------------------------------
BRDT_Mmus ------------RVLLGPPVVHT------------SA-E-SLTVLE--------------
BRD4_Mmus ------------PVDIGRPVIRPPEQSAPPPGA----PDKDKQKQE--------------
BRD3_Mmus --------------------------GSAPSGG----PSRL-------------------
BRD2_Mmus ------------------------ES-SAQQVA----VSRL-------------------
BRD2_Hsap ------------------------ESSSAQQVA----VSRL-------------------
BRD3_Hsap --------------------------GSAPSGG----PSRL-------------------
BRD4_Hsap ------------PVDVGRPVIRPPEQNAPPPGA----PDKDKQKQE--------------
BRDT_Hsap ------------QLSNGITVMHP------------SG-DSDTTMLE--------------
Y119C1B.8_Cele --------------AIGK---------------NNAA--ASSNSYR--------------
DDB0220693_Ddis ---------------------------------STSS--TSNTTLTPIIQQSSLTHASSP
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur DLEGEGESPSTSPVMTGHKTEESNGSSHPEGGMPSSASSENLSKME--------------
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ---------------------------------STPA--GPSK-AQ--------------
AqueK041_Aque -------------------------------GF-----------QE--------------
BRDT_Mmus ----------PECHAPAQKDIKIKN--ADSWKSLGK--P--VKAS--SVLKSSDELFNQF
BRD4_Mmus ----------PKTPVAPKKDLKIKN--MGSWASLVQKHP--TTPS--STAKSSSDSFEHF
BRD3_Mmus ----------------------------SSSS----SSE--SASS--SSSGSSSDS----
BRD2_Mmus ----------------------------SASS---SSSD--SSSS--SSSSSSSDT----
BRD2_Hsap ----------------------------SASS---SSSD--SSSS--SSSSSSSDT----
BRD3_Hsap ----------------------------SSSS----SSE--SGSS--SSSGSSSDS----
BRD4_Hsap ----------PKTPVAPKKDLKIKN--MGSWASLVQKHP--TTPS--STAKSSSDSFEQF
BRDT_Hsap ----------SECQAPVQKDIKIKN--ADSWKSLGK--P--VKPS--GVMKSSDELFNQF
Y119C1B.8_Cele ----------YRCFFVRKLNLKISN--KKKWKSKKN--S--TNLVFRSSKTCTSTSTNII
DDB0220693_Ddis ISSSTFVSFSSSSSTPPTNNLSPPSPGLPNSPSINS--P--SSPS--ANNNNTDSAWNHF
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur ----------QKASSKDKKDMKLPN--RYSWSNLANT-PSSTKPS-SKPTKTSHHSFELF
F13C5.2_Cele -------------------------P----------------------------------
F57C7.1b_Cele -------------------------P----------------------------------
AqueK041_Aque ----------PIE---------------------M----GGVK-K-R-AIPSADSSFAQF
BRDT_Mmus RKAAIEKEVKART----QEQMRKHLEHNAK--DPKVSQENQ--REPGSGLTLESLSSKVQ
BRD4_Mmus RRAAREKEEREKALK-AQAE---HAEKE--KERLRQERMRS--REDEDALEQARRAHEEA
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap RRAAREKEEREKALK-AQAE---HAEKE--KERLRQERMRS--REDEDALEQARRAHEEA
BRDT_Hsap RKAAIEKEVKART----QELIRKHLEQNTK--ELKASQENQ--RDLGNGLTVESFSNKIQ
Y119C1B.8_Cele -KTSGSTE---TTVK-TKENGRNQQR------RLRLDHQRK--ANPG---------MVKT
DDB0220693_Ddis KAKNITLKQKEKERVLQEEVLRKEREEKEE--ELKKEEEKK--RI-----------EMEE
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur KKAAKEKEERTRQIK-QQEEMRKQQKHLQEQERARQERERQ--RE-----------KEED
F13C5.2_Cele ------------------------------------------------------------
F57C7.1b_Cele ------------------------------------------------------------
AqueK041_Aque KKQALENAEREKANK-QQEDLRKQQIMLMQQNKKETESKSNTASP-----------VGGG
BRDT_Mmus DKSLEEDQSEQQPPSEA-QD------------------VSKLWLLKDRNLAREKEQERRR
BRD4_Mmus RRRQEQQQQQQQQRQEQQQQQQQAAAVAAASAPQAQSSQPQSMLDQQRELARKREQERRR
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap RRRQEQQQQQRQ--EQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRR
BRDT_Hsap NKCSGEEQKEHQQSSEA-QD------------------KSKLWLLKDRDLARQKEQERRR
Y119C1B.8_Cele SRPGFRGCGWR-QS-EPA---------------------------------------K--
DDB0220693_Ddis IKRLAKEKEER-EA-EET----------------------RKQIESERAAAREA-REKEK
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur -DALERARNSQ-QE-EAK----------------------RTQSMKER--ERLREQERRK
F13C5.2_Cele ----------------------------------------AAEHSSIQSSE-AQALG--E
F57C7.1b_Cele ----------------------------------------AVVRPSSKSVASKPAYTKRT
AqueK041_Aque -------GGAD-SG-GMN----------------------SPVDEVER--ERLKEKQRQE
BRDT_Mmus REAM----AGTIDMTLQSD--IM-------------------------------------
BRD4_Mmus REAM----AATIDMNFQSD--LL-------------------------------------
BRD3_Mmus ------------------------------------------------------------
BRD2_Mmus ------------------------------------------------------------
BRD2_Hsap ------------------------------------------------------------
BRD3_Hsap ------------------------------------------------------------
BRD4_Hsap REAM----AATIDMNFQSD--LL-------------------------------------
BRDT_Hsap REAM----VGTIDMTLQSD--IM-------------------------------------
Y119C1B.8_Cele ---------------KKTK--AV-------------------------------------
DDB0220693_Ddis LNNS----KGNMSFQYQMD--VM-------------------------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur REAY----HEMLSWGFEDSSQIISTLLVYLDLCEGKNWWHMEIHPCWPLHMAYITGRAFK
F13C5.2_Cele ISGAHPIHIGESEIAGHAA--DS-------------------------------------
F57C7.1b_Cele LSES----SSSSDSNGSSS--DS-------------------------------------
AqueK041_Aque REKM----KQQIDMTYQND--LM-------------------------------------
BRDT_Mmus ---------------------TM-------------------------------------
BRD4_Mmus ---------------------SIF------------------------------------
BRD3_Mmus -----------------------S------------------------------------
BRD2_Mmus -----------------------S------------------------------------
BRD2_Hsap -----------------------S------------------------------------
BRD3_Hsap -----------------------S------------------------------------
BRD4_Hsap ---------------------SIF------------------------------------
BRDT_Hsap ---------------------TM-------------------------------------
Y119C1B.8_Cele ---------------------SRC------------------------------------
DDB0220693_Ddis ---------------------ASFEDNIDSSGSLLNL-----------------------
DDB0220694_Ddis ------------------------------------------------------------
BRD_Spur KDDITAVLPLQAKATLSPSSLRTFLTTLDPEHSSLQSSFKTPSKAVIPEEHRAKRAITLA
F13C5.2_Cele ----------------------TT------------------------------------
F57C7.1b_Cele ---------------------SDS------------------------------------
AqueK041_Aque ---------------------SQ-------------------------------------
BRDT_Mmus --------------------------------------FENNFD
BRD4_Mmus ---------------------------------------EENLF
BRD3_Mmus -----------------------------------------DSE
BRD2_Mmus ---------------------------------------DSDSG
BRD2_Hsap ---------------------------------------DSDSG
BRD3_Hsap -----------------------------------------DSE
BRD4_Hsap ---------------------------------------EENLF
BRDT_Hsap --------------------------------------FENNFD
Y119C1B.8_Cele ---------------------------------------QTKWK
DDB0220693_Ddis -----------------------------------QLKPIEDPL
DDB0220694_Ddis ---------------------------------------QKQDE
BRD_Spur ITDSDSTIVYYKISDGLVPPDSGPKIPTEDGSDDGGKEEGRASL
F13C5.2_Cele ---------------------------------------GESHA
F57C7.1b_Cele ---------------------------------------DSEPS
AqueK041_Aque --------------------------------------FEMTMY