GSK3B_Hsap MSGRPRTT----------------------------------------------------
GSK3A_Hsap MSGGGPSGGGP----------------G--------------------------------
Pk34A_Dmel MENKEKKQKPLK------------------------------------------------
sgg_Dmel MFTFYTNINNTLINNNNNNNNTSNSNNNNNNVISQPIKIPLTERFSSQTSTGSADSGVIV
gskt_Dmel MASQSKNSG---------------------------------------------------
GSK3B_Mmus MSGRPRTT----------------------------------------------------
GSK3A_Mmus MSGGGPSGGGP----------------G--------------------------------
R03D7.5_Cele MANFIRLAYN--------------------------------------------------
F21F3.2_Cele MSVTVEQ-----------------------------------------------------
C44H4.6_Cele MNRMRRSTAFS-------------------------------------------------
C36B1.10_Cele MPNTYRTSDE--------------------------------------------------
RIM11_Scer MNIQSNNSPNLS------------------------------------------------
MRK1_Scer MTDVLRSLVRKI------------------------------------------------
MCK1_Scer MSTEEQNG--V-------------------------------------------------
Y106G6D.4_Cele MNEDENKGIV--------------------------------------------------
Y106G6E.1_Cele MPNIYRTTDE--------------------------------------------------
Y18D10A.5_Cele MNKQLLSC----------------------------------------------------
YOL128C_Scer MLKVNNVFGSN-------------------------------------------------
GlkA_Ddis MTIPTDNNSSNN------------------------------------------------
GSK-3_Ddis MSSKDQILE-K-------------------------------------------------
19912_Tthe MLSQTVPLSSVL------------------------------------------------
19923_Tthe MGGNGSRMH---------------------------------------------------
19924_Tthe MNMRIPTQNYD-------------------------------------------------
2636_Tthe MIKREILIKSKI------------------------------------------------
5825_Tthe MNVSQSQGNVMQ------------------------------------------------
7876_Tthe MYNNMTSNKPN-------------------------------------------------
GSK3_Spur MCTVERPASGEW---------------S--------------------------------
n1163_Tthe MAEFQQETEQLK------------------------------------------------
CC1G_03802_Ccin MATHGPING---------------------------------------------------
AqueK117_Aque MSSTFNKKEPP-------------------------------------------------
GSK_b_Smoe MESRVDSMQ-E-------------------------------------------------
GSK_a-2_Smoe MASASVGPVGA-------------------------------------------------
GSK_a-1_Smoe MASASVGPVGA-------------------------------------------------
GK035_Glam MLPQKLPEL---------------------------------------------------
GK036_Glam MSDDETAFPPE-------------------------------------------------
*
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ----------GSGRARTS------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel SSASQQQLQLPPPRSSSG------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ----------GSGRARTS------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer -------------SFNNS------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ----------------S-------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ----------THRRPVSS------------------------------------------
n1163_Tthe ----------------QLLQATYQGTSTEQVKHAEKELQNVSHHQDFLKYLVYIMKDTAN
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque -------------RIRTT------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------IRGSTS------------------------------------------
GSK_a-1_Smoe ------------IRGSTS------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap --------------------------------S---F-AES----C--------------
GSK3A_Hsap --------------------------------S---F-AEP----G--------------
Pk34A_Dmel --------------------------------R---H-----------------------
sgg_Dmel --------------------------------S---L-SLP----Q--------------
gskt_Dmel ------------------------------------L-----------------------
GSK3B_Mmus --------------------------------S---F-AES----C--------------
GSK3A_Mmus --------------------------------S---F-AEP----G--------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer --------------------------------N---N--------I--------------
MRK1_Scer --------------------------------D---NLQLKHKTSI--------------
MCK1_Scer ------------------------------------P-----------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele --------------------------------S---L-----------------------
YOL128C_Scer ------------------------------------P-----------------------
GlkA_Ddis --------------------------------KGYND--------NNNNNNNNNNNNNNN
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe --------------------------------E---VLPQQRVNA---------------
19923_Tthe ------------------------------------------------------------
19924_Tthe --------------------------------K---E--------V--------------
2636_Tthe --------------------------------S--KN--------S--------------
5825_Tthe --------------------------------Q---N--------L--------------
7876_Tthe --------------------------------N---R--------L--------------
GSK3_Spur --------------------------------A---Y-SKI----V--------------
n1163_Tthe PLLMQKSASNYVHVYVRNIYSKTSQSGQIQQIQ---E--------I--------------
CC1G_03802_Ccin ------------------------------------V-----------------------
AqueK117_Aque --------------------------------S---F-ADP----M--------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe --------------------------------A---I-VVS-------------------
GSK_a-1_Smoe --------------------------------A---I-VVS-------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap -K----------------------------------------------------------
GSK3A_Hsap -G---------------GGGGGGGGPGGSASGP----GGTGGGKASVGAMGGGVGASSSG
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel -APPGGKWRQKQQRQQLLLSQDSGIENGVTTRPSKAKDNQGAGKASHNATS--SKESGAQ
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus -K----------------------------------------------------------
GSK3A_Mmus -G---------------GGGGGGGGPGGSASGP----GGTGGGKASVGAMGGGVGASSSG
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis NN----------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe -I----------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur -M----------------------------------------------------------
n1163_Tthe ------------------------------------------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque -G----------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ---------------------------------------------P-V------------
GSK3A_Hsap G--------------------------------GPGGSGGGGSGGP-G------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel SNSSSESLGSNCSEAQEQQRVRASSALELSSVDTPVIVGGVVSGGN-SILRSRIKYKSTN
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ---------------------------------------------P-V------------
GSK3A_Mmus G--------------------------------GPSGSGGGGSGGP-G------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe -----------------------------------------------L------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ---------------------------------------------PRI------------
n1163_Tthe ------------------------------------------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ----------------------------------------------RE------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ----------------------------------------------KV------------
GSK_a-1_Smoe ----------------------------------------------KV------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ---------------------------------------------------------Q--
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel STGTQGFDVEDRIDEVDICDDDDVDCDDRGSEIEEEEEDQTEQEEEVDEVDAKPKNRL--
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ---------------------------------------------------------Q--
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ---------------------------------------------------------Q--
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ---------------------------------------------------------NNN
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ---------------------------------------------------------Q--
19923_Tthe ------------------------------------------------------------
19924_Tthe ---------------------------------------------------------L--
2636_Tthe ---------------------------------------------------------PKA
5825_Tthe ---------------------------------------------------------Q--
7876_Tthe ---------------------------------------------------------N--
GSK3_Spur ---------------------------------------------------------S--
n1163_Tthe ---------------------------------------------------------T--
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ---------------------------------------------------------T--
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ---------------------------------------------------------G--
GSK_a-1_Smoe ---------------------------------------------------------G--
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap -QP--S------------------------------------------------------
GSK3A_Hsap -AG--T------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel -LP--PDQAELTVAAAMARRRDAKSLATDGHIYFPLLKISEDPHIDSKLINRKDGLQDTM
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus -QP--S------------------------------------------------------
GSK3A_Mmus -AG--T------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer -SN--T------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis N-----------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe -Q---Y------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe FF----------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur -ST--K------------------------------------------------------
n1163_Tthe ------------------------------------------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe -GSGVD------------------------------------------------------
GSK_a-1_Smoe -GSGVD------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ----------------------------A-------------------------------
GSK3A_Hsap ----------------------------S-------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel YYLDEFGSPKLREKFARKQKQLLAKQQKQLMKRERRSEEQRKKRNTTVASNLAASGAVVD
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ----------------------------A-------------------------------
GSK3A_Mmus ----------------------------S-------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ----------------------------A-------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ----------------------------A-------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ----------------------------I-------------------------------
n1163_Tthe ------------------------------------------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ----------------------------Q-------------------------------
GSK_a-1_Smoe ----------------------------Q-------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------F---------G-------------------------
GSK3A_Hsap ------------------------F---------P-------------------------
Pk34A_Dmel -----------------------------------A------------------------
sgg_Dmel DTKDDYKQQPHCDTSSRSKNNSVPN---------P--P----------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------F---------G-------------------------
GSK3A_Mmus ------------------------F---------P-------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------LEK---KKRKPDTIKKVSDVQVHHTVPNFNNSSEYI
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer -----------------------------------N------------------------
GlkA_Ddis ------------------------------NNKEHPN-----------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------FGESPQKTKRSN---KTQD-----RVSLFNGS----
19923_Tthe ------------------------------------------------------------
19924_Tthe ----------------------------------PT------------------------
2636_Tthe ------------------------FFFFFFKQFQQKN-----------------------
5825_Tthe ----------------------------------QQ------------------------
7876_Tthe -----------------------------------D------------------------
GSK3_Spur ------------------------L---------PPSS----------------------
n1163_Tthe ----------------------------------EQ------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------R---------PPQV----------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------L---------PEEM----------------------
GSK_a-1_Smoe ------------------------L---------PEEM----------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer NDIENLIISKL-------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ---ASIMMTTI-------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ----------Q-------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe ----------IILAMRDSNISIDCKHNISKGLSIILSLDRPQTWILQDDITQLASTLIIL
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe QTVIISTQQKEFLAHFFNLLNMPFCQVGSNYLTEITSSLQLLEKSQNEQETTQIFQKTVE
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe GIKVLNLWAIVLKDLIIQVMESKNRKLISFVLENEILANLICHGICVTLNTPLQIKDCLI
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe CTSGQSDFDDAANTLKSHLIKAYTRINRQMFAERSKFDIFKTQFFKLLQQSLPIILKGLM
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe LFCQQTPDFQDKLENKSLSSIVIECLKFSHICAEQSEFYKIFQDCSRVLLLEVIFPLMRS
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe SQSEQESLENNPEEFVRLALDTCDRQISYSYKCAAAKLLETVCDYIDGFETIVSLLLIQI
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe VGFSIKFENITDVDANYPNLIPFKETVFMSKTERHIRIETCFVALSVLSYLTPKRPDIVG
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe QIELLLKEHAQFLFNHNIHRLIKVRVCLMLGYYTDSVFQNEKENYKSLIQFLLSCLTLKE
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer -IDGG-------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe -Q----------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe -ADEG-------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe QEDQGIVYQAIDSLQNIYDDDNQVNLVSENINEVLHVILPLITTTEFHQFMDIVFHIFRY
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe HSKNIAPQNIINCVGYLVKRIIDEVKLIDDKLRNDQIYINKCWNIIRDMSDNKFIVPQYI
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe NSILEQLRPLLQCVQYPEKIEFDEDIILLVGSFIYHQKAVNPICSDLITCFPLILKKQQG
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ---------------------------------------------------KEGIAVD--
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------SKAD--
19923_Tthe ------------------------------------------------------------
19924_Tthe ---------------------------------------------------I-GSRVH--
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe VFAQLFKTLNNVIIYGQEFLIQNASHLQLIIKMAYDTMFSDSSKSTDSDKAE-GAAIMQL
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe IVQSLGNNLTDEMWKIIFNAAIQRFQSQTKLRHSFAYGRTAGIFLSGFNSNIQKSTQILT
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe EMGLLEQVIILCVSKLEMYKRNYDIKLFIMSMSKVIVQVSLDANKVLQIFDCLISLMMKQ
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel -------------SSHLHQNHNHLVVDVQEDVDDVNVVATSDVDSGVVKMRRHSHDNHYD
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer -----------HIE----------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------IN----------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe -----------TLP----------------------------------------------
19923_Tthe -----------TVG----------------------------------------------
19924_Tthe -----------TVG----------------------------------------------
2636_Tthe ------------LQ----------------------------------------------
5825_Tthe -----------QLA----------------------------------------------
7876_Tthe -----------EIN----------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe KELEQKLEKKRKLK----------------------------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe -------------H----------------------------------------------
GSK_a-1_Smoe -------------H----------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------F-----------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel RIPRSNAATITTRPQIDQQSSHHQNTEDVEQGAEPQIDGEADLDADADADSDGSGENVKT
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe --------------PID-------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe ------------------------------------------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap -------S------------M------KVSRD----------------------------
GSK3A_Hsap -------P------------P------GVKLG----------------------------
Pk34A_Dmel ---------------------------QVPL-----------------------------
sgg_Dmel AKLARTQS------------C------KNQTG----------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus -------S------------M------KVSRD----------------------------
GSK3A_Mmus -------P------------P------GVKLG----------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer -------H------------A------NISDS----------------------------
MCK1_Scer ----------------------------LQR-----------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ---------------------------RMTKL----------------------------
GlkA_Ddis -------NNNNNNNNNNNNNI------KESSS----------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------QY------------SKYRQNTQASNS----------------------------
19923_Tthe -------S------------M------KESDK----------------------------
19924_Tthe -------S------------M------KENEY----------------------------
2636_Tthe -------QFYKNQQQKNDTFI---------------------------------------
5825_Tthe ----------------------------QQQQ----------------------------
7876_Tthe ----------------------------QNHQ----------------------------
GSK3_Spur -------S------------S------KSIRD----------------------------
n1163_Tthe ----------------------------DDDNNNNSDDEGDDDDYDDDDDDDEDDDEEVD
CC1G_03802_Ccin ---------------------------KISPI----------------------------
AqueK117_Aque ------GG------------M------RVTRD----------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe -------E------------M------KIRDD----------------------------
GSK_a-1_Smoe -------E------------M------KIRDD----------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe GDEDNDLNVNHYDKEYDCSVNADKLMLKEMVSPINDVDEFAIFKQSYSTMKSQNFTALQQ
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ---------------------------------K--------------------------
GSK3A_Hsap ---------------------------------R--------------------------
Pk34A_Dmel ---------------------------------I--------------------------
sgg_Dmel ---------------------------------R--------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ---------------------------------K--------------------------
GSK3A_Mmus ---------------------------------R--------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ---------------------------------K--------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ---------------------------------K--------------------------
YOL128C_Scer ---------------------------------E--------------------------
GlkA_Ddis ---------------------------------S--------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ---------------------------------K--------------------------
19923_Tthe ---------------------------------K--------------------------
19924_Tthe ---------------------------------Q--------------------------
2636_Tthe ---------------------------------L--------------------------
5825_Tthe ---------------------------------A--------------------------
7876_Tthe ---------------------------------K--------------------------
GSK3_Spur ---------------------------------K--------------------------
n1163_Tthe LVYGLNQEKQKYLAQLLSVQRVNVGSEQVIRLRGGGGECHLISFISILKNIIYIFRIQKR
CC1G_03802_Ccin ---------------------------------D--------------------------
AqueK117_Aque ---------------------------------K--------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ---------------------------------K--------------------------
GSK_a-1_Smoe ---------------------------------K--------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe IFADLSASALEIIFSSRQIENLIFEISHFFRKMKESFFTLKKFNFRKENENLRINRLVSY
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer -----------T------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe -----------SPQ----------------------------------------------
19923_Tthe -----------QD-----------------------------------------------
19924_Tthe ------------K-----------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe KNLQGKGAIDLRPPTSSQFQKTISFLERMRDKQIDRNKRQQQIKLAEKEQMTDHSLTNLF
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe -----------TDH----------------------------------------------
GSK_a-1_Smoe -----------TDH----------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis --------------------------------------------------------DK-K
19912_Tthe --------------------------------------AKNKKYNYGGGGDFFTQKI---
19923_Tthe --------------------------------------PKVQ-------------KL---
19924_Tthe --------------------------------------KQQQ-------------KI---
2636_Tthe ------------------------------------------------------------
5825_Tthe --------------------------------------QQQQ-------------Q----
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe IEQVLISFSNQLIIKQNKQSKQSANNQLQKKESKTGNQKRKK-------------KI---
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe --------------------------------------------------------VEAA
GSK_a-2_Smoe --------------------------------------SDDK-------------ELEAT
GSK_a-1_Smoe --------------------------------------SDDK-------------ELEAT
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap --------------D--GSK--V-------------------------------------
GSK3A_Hsap --------------D--SGK--V-------------------------------------
Pk34A_Dmel ------------------IP--K-------------------------------------
sgg_Dmel --------------D--GSK--I-------------------------------------
gskt_Dmel -----------------TNK--V-------------------------------------
GSK3B_Mmus --------------D--GSK--V-------------------------------------
GSK3A_Mmus --------------D--SGK--V-------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele --------------E--HVT--F-------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer --------------V--SKQ--V-------------------------------------
MRK1_Scer --DGK--VANKHENI--SSK--L-------------------------------------
MCK1_Scer --------------G--SEF--I-------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele --------------S--GKQ--V-------------------------------------
YOL128C_Scer --------------D--EHY--F-------------------------------------
GlkA_Ddis --------------N--SNH--S-------------------------------------
GSK-3_Ddis ETDD----------N--GNK-KT-------------------------------------
19912_Tthe -SKKQPSLHTQQS-NSTYNQLRS-------------------------------------
19923_Tthe ---------------------QI-------------------------------------
19924_Tthe ---------------------QM-------------------------------------
2636_Tthe --------------L--AD---D-------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur --------------D--SSK--I-------------------------------------
n1163_Tthe ---------------------QFQMNNMKKQYGQPMNVSQSQGNVMQSQNLQQQQLAQQQ
CC1G_03802_Ccin --------------D--PHK--V-------------------------------------
AqueK117_Aque --------------D-TGHR--I-------------------------------------
GSK_b_Smoe VIDG----------N--GTE--T-------------------------------------
GSK_a-2_Smoe VVDG----------N--GTE--T-------------------------------------
GSK_a-1_Smoe VVDG----------N--GTE--T-------------------------------------
GK035_Glam ----------------------F-------------------------------------
GK036_Glam -----------------ELQ--L-------------------------------------
GSK3B_Hsap ----TT-----VV-----------------------ATP-G-QGP------------DRP
GSK3A_Hsap ----TT-----VV-----------------------ATL-G-QGP------------ERS
Pk34A_Dmel ----NS-----VI-----------------------STYAVGRLC------------SEP
sgg_Dmel ----TT-----VV-----------------------ATP-G-QGT------------DRV
gskt_Dmel ----TT-----VV-----------------------ATN-A-FGA------------DVM
GSK3B_Mmus ----TT-----VV-----------------------ATP-G-QGP------------DRP
GSK3A_Mmus ----TT-----VV-----------------------ATV-G-QGP------------ERS
R03D7.5_Cele -----L-----E------------------------VWKL--IEV------------HKT
F21F3.2_Cele ------------E-----------------------AYEM--PAD------------NKK
C44H4.6_Cele ----HT-----VM-----------------------AKRGTGSKL------------DRE
C36B1.10_Cele -----------IV-----------------------AQR---LED------------GRD
RIM11_Scer ----YY------------------------------AHPPPTIDP------------NDP
MRK1_Scer ----SKEKVEKMINFDYRYIKTKERTIHKRVYKHDRKTDVDRKNH------------GGT
MCK1_Scer ----AD-----DV-------------------------T-S-NKS------------NNT
Y106G6D.4_Cele -----F-----QI-----------------------AYEL--PS-------------QQR
Y106G6E.1_Cele -----------IV-----------------------AQR---LED------------GKD
Y18D10A.5_Cele ----TM-----VV-----------------------ASV-ATDGV------------DQQ
YOL128C_Scer ----ID-----DI-------------------------V-S-IKN------------RQK
GlkA_Ddis ----SS-----QS-----------------------S-STA-TVN------------SNP
GSK-3_Ddis ----TT-----TT-----------------------SSSSSSSSSSKPRSNKFDKVIIKS
19912_Tthe ----SS-LTNRFN-----------------------KTP--SRLF------------NIN
19923_Tthe ----LK-----RI-----------------------YE-IQFTQQ------------QKE
19924_Tthe ----T------YF-----------------------YN-EKQQAG------------NYT
2636_Tthe ----TI-----KV-----------------------F-PLL-KLD------------KMI
5825_Tthe ------------L-----------------------QQ-QQQEQL------------QYS
7876_Tthe ------------L-----------------------DH--KG------------------
GSK3_Spur ----TS-----VT-----------------------ATK-G-PPP------------DRA
n1163_Tthe QAQQQQ-----QL-----------------------QQ-QQQEQL------------QYS
CC1G_03802_Ccin ----VR-----VI-----------------------ASD-G-KT-------------GET
AqueK117_Aque ----MT-----VM-----------------------GTL-G-PLP------------DRQ
GSK_b_Smoe ----GH-----II-----------------------ATTIGGRNG------------QPK
GSK_a-2_Smoe ----GH-----II-----------------------ATTIGGRNG------------QPK
GSK_a-1_Smoe ----GH-----II-----------------------ATTIGGRNG------------QPK
GK035_Glam ----QD-----ST-----------------------ATC-P-QS-------------TDG
GK036_Glam ----GK-----AL-------------------------DI--PGE------------KGE
GSK3B_Hsap QEVSYTDTKVIGNGSFGVVYQAK-------------LC---DSG----ELVAIKKVLQDK
GSK3A_Hsap QEVAYTDIKVIGNGSFGVVYQAR-------------LA---ETR----ELVAIKKVLQDK
Pk34A_Dmel ALVRIEVKDLIGSGSFGRVYQAH-------------VN---ESE----EIVAVKQTLYNP
sgg_Dmel QEVSYTDTKVIGNGSFGVVFQAK-------------LC---DTG----ELVAIKKVLQDR
gskt_Dmel SEISYTDAKVVGNGSFGVVFQAK-------------MV---PSN----EMVAIKKVLQDR
GSK3B_Mmus QEVSYTDTKVIGNGSFGVVYQAK-------------LC---DSG----ELVAIKKVLQDK
GSK3A_Mmus QEVAYTDIKVIGNGSFGVVYQAR-------------LA---ETR----ELVAIKKVLQDK
R03D7.5_Cele TKKAISAHKLCGSGRFSNVYCGQ-------------MI---SP-IE--KEVAVKNVWSDT
F21F3.2_Cele VMLKIEEVHLHSCGVFSNVYKGI-------------LR---EP-YE--KKIAIKKSWPEK
C44H4.6_Cele VEIQFTNLQLIGTGSFGAVYKAV-------------LR---END----EPIAIKKIKVDD
C36B1.10_Cele MNLSLQNMNLFASGAFSNVYRGI-------------ART--ESNHQ--MEIVIKKTWPRH
RIM11_Scer VQISFPTTEVVGHGSFGVVFATV-------------IQ---ETN----EKVAIKKVLQDK
MRK1_Scer IDISYPTTEVVGHGSFGVVVTTV-------------II---ETN----QKVAIKKVLQDR
MCK1_Scer RRMLVKEYRKIGRGAFGTVVQAY-------------LT---QDKKNWLGPFAIKKVPAHT
Y106G6D.4_Cele VGMQMANLRLHARGVFSNVYRGT-------------IL---SPGTE--QEIAIKKTWPKT
Y106G6E.1_Cele MHLNLHHMNLFATGAFSNVYRGV-------------AQT--ESNQE--IDIVIKKTWPRH
Y18D10A.5_Cele VEISYYDQKVIGNGSFGVVFLAK-------------LS---TTN----EMVAIKKVLQDK
YOL128C_Scer SKMYVREGKRIGHGSFGTVTQSI-------------LS---SNSIEWLGPYAIKRVVKSP
GlkA_Ddis KVYPYEIIKQVGQGTFGKVYEAK-------------NQ---D-N----KRVAIKKVEKSN
GSK-3_Ddis NGVCYITEGVIGNGSFGVVTQAI-------------VA---DTK----EVVAIKKVLQDQ
19912_Tthe QNLDIDENNKIGQGNFGVVFKAE-------------FK---DTK----EEVAVKRVLQDK
19923_Tthe YTYSIQGDNIVGNGTFGA----T-------------IN---ETG----ETVAIKKVFQDR
19924_Tthe YTIVGDEDKVVGSGTFGVVYQAT-------------TK---ETG----EVVAIKKVFQDK
2636_Tthe PLPNYEIKRVIGSGSFGYVFEAY-------------DN---NNQ----RTVALKRIQKVG
5825_Tthe GSPNITLDKIIGNGTFGVVYLAK-------------MN---DTQ----EQVAIKKVFQDK
7876_Tthe PPKDLKIIDVVGNGTFGVVYKKLDDNINFNYLKMKALL---NKE----QVVAVKRVFQDK
GSK3_Spur EEISYTDTRVIGNGSFGVVYQAR-------------MV---DSS----DLVAIKKVLQDK
n1163_Tthe GSPNITLDKIIGNGTFGVVYLAK-------------MN---DTQ----EQVAIKKVFQDK
CC1G_03802_Ccin RELSYTNCKVIGNGSFGVVFQAR-------------LLGVPKDQ----EDIAIKKVLQDK
AqueK117_Aque QEITYTDLKVIGSGSFGVVYQAK-------------IL---ETN----EPIAIKKVLQDK
GSK_b_Smoe QTISYVAERVVGTGSFGIVFQAK-------------CL---ETG----ETVAIKKVLQDK
GSK_a-2_Smoe QTISYVAERVVGTGSFGIVFQAK-------------CL---ETG----ETVAIKKVLQDK
GSK_a-1_Smoe QTISYVAERVVGTGSFGIVFQAK-------------CL---ETG----ETVAIKKVLQDK
GK035_Glam PEITFTTMRTIGSGSFGVVFIAK-------------T----STG----ELIAIKKVFQDR
GK036_Glam EGIQVVPEKVIGKGSFGVVYLVK-------------SL---KGN----TPLALKLVLQDR
. * *. .:*
GSK3B_Hsap RFKN------RELQIM---RKL-DHCNIVRLR-YFFYSSGE-------------------
GSK3A_Hsap RFKN------RELQIM---RKL-DHCNIVRLR-YFFYSSGE-------------------
Pk34A_Dmel KLSQ------GEAEIMGQL--K-DHNNIVRLI-MHSSVSLG-------------------
sgg_Dmel RFKN------RELQIM---RKL-EHCNIVKLL-YFFYSSGE-------------------
gskt_Dmel RFKN------RELQIM---RKL-RHDNIITLK-WFFFSSGE-------------------
GSK3B_Mmus RFKN------RELQIM---RKL-DHCNIVRLR-YFFYSSGE-------------------
GSK3A_Mmus RFKN------RELQIM---RKL-DHCNIVRLR-YFFYSSGE-------------------
R03D7.5_Cele ETRHLATSEYPEIQIL---SKL-FHPAISNLL-YFYSRNAND------------------
F21F3.2_Cele GERN------FEFIFLTGRERA-KHKNVIHMI-FAFSHSYDT------------------
C44H4.6_Cele RFKS------RELTIM---HEM-DHPNIIRLL-YYYVM----------------------
C36B1.10_Cele KGCP------LEVKILGKLGKL-KHKNIVRLL-FSY-QK-Q-------------------
RIM11_Scer RFKN------RELEIM---KML-SHINIIDLK-YFFYERD--------------------
MRK1_Scer RYKN------RELETM---KML-CHPNTVGLQ-YYFYEKD--------------------
MCK1_Scer EYKS------RELQIL---RIA-DHPNIVKLQ-YFFTHLSP-------------------
Y106G6D.4_Cele PYRN------FELLFLSGLRRK-PHKNIVQML-FAFSRNTTSGEGLE-------------
Y106G6E.1_Cele KGCP------MEVKILGQLGKL-KHRNIVRLL-YSY-QK-Q-------------------
Y18D10A.5_Cele RFKN------RELQIM---RKL-NHPNIVKLK-YFFYSSGE-------------------
YOL128C_Scer KVQS------LELEIL---QNI-RHPNLVTLE-FFFESHCT-------------------
GlkA_Ddis HFIS------REYDIL---KIVA-HPNCLRIL-DMFYTAE--------------------
GSK-3_Ddis RYKN------RELQIM---KML-NHINIVSLK-NSFYTS---------------------
19912_Tthe NFKN------RELQIM---QEVAHHPNIVQLK-YSFYSFGE-------------------
19923_Tthe RYKN------RELQIM---KEIGNHPNVISLR-NYFYIYADD------------------
19924_Tthe RYKN------RELQMM---KEIGNHPNVIKLR-NHYYSYG-N------------------
2636_Tthe KKLS------REYEIL---LDIKDCDYVVKMI-DLYYSKT--------------------
5825_Tthe RYKN------REFEII---KSL-NHQNLIKLK-QAYYTTQNN------------------
7876_Tthe RYKN------REREII---ERL-DHQNIIKCK-DFFETKGE-------------------
GSK3_Spur RFKN------RELQIM---RRL-DHHNIVKLK-YFFYSSGE-------------------
n1163_Tthe RYKN------REFEII---KSL-NHQNLIKLK-QAYYTTQNN----NVDSFFFHTFNSKI
CC1G_03802_Ccin RFKN------RELQIM---RLV-SHPNVVDLK-AFFYSNGD-------------------
AqueK117_Aque RFKQ--------------------------------------------------------
GSK_b_Smoe RYKN------RELQIM---RLL-DHPSIVSLK-HCFFSTT--------------------
GSK_a-2_Smoe RYKN------RELQIM---RLL-DHPNIVALK-HCFFSTT--------------------
GSK_a-1_Smoe RYKN------RELQIM---RLL-DHPNIVALK-HCFFSTT--------------------
GK035_Glam KYRN------RELSIM---QELGQHPCIIRLI-NSYISVATN------------------
GK036_Glam RYKN------REFQIM---RTL-VHPCICRLVKGTFIPSIS-------------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe NSQLRFFLRYKKTQNCLHSLIQFTRYIQKHSKKSNTKTLIQIFNLRELDFPASHPVFYTN
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ----------KKDE--VY-LNLVLDYVPETVYRVARHYSR-------AKQTLPVIYVKLY
GSK3A_Hsap ----------KKDE--LY-LNLVLEYVPETVYRVARHFTK-------AKLTIPILYVKVY
Pk34A_Dmel ----------FPSV--DY-VLLVMEYMPMTLLDYINYHLTV------LQPAERLINVRIL
sgg_Dmel ----------KRDE--VF-LNLVLEYIPETVYKVARQYAK-------TKQTIPINFIRLY
gskt_Dmel ----------KRDE--VY-LNLVMEFLPETLYKVERQYAR-------AKQTLPVNFVRLY
GSK3B_Mmus ----------KKDE--VY-LNLVLDYVPETVYRVARHYSR-------AKQTLPVIYVKLY
GSK3A_Mmus ----------KKDE--LY-LNLVLEYVPETVYRVARHFTK-------AKLITPIIYIKVY
R03D7.5_Cele -------------K--VI-NCLVLDYLPQDLARLRDQ-----------GVKFDVLDAKLY
F21F3.2_Cele -------------K--VC-ESYVFDFMPNTLAEVIRQ-------------KLTDLDIRLY
C44H4.6_Cele -----------QQE--NC-LNFVMEFMPKDLAYVHRQFAH-------NDKQMPAYSIKLY
C36B1.10_Cele ----------HEGR--IC-LGLIFEYIPMNLHQFLKDNN----------RRVDIIEVKLI
RIM11_Scer ----------SQDE--IY-LNLILEYMPQSLYQRLRHFVH-------QRTPMSRLEIKYY
MRK1_Scer ----------EEDE--VY-LNLVLDYMPQSLYQRLRHFVN-------LKMQMPRVEIKFY
MCK1_Scer ----------QDNK--VY-QHLAMECLPETLQIEINRYVT-------NKLEMPLKHIRLY
Y106G6D.4_Cele ----------MKHS--FC-ESYVFGFMPYTLQNILKK------------TRLAEVDMKLY
Y106G6E.1_Cele ----------HEGR--IC-LALIFEYIPLNLYQFLKDKN----------RRIDIVEVKLI
Y18D10A.5_Cele ----------KKDE--LY-LNLILEYVPETVYRVARHYSK-------QRQQIPMIYVKLY
YOL128C_Scer ----------TKDGGHLYQKNFVMEYIPQTLSSEIHEYFD-------NGSKMPTKHIKLY
GlkA_Ddis ----------D-NK--KM-QNLVFDFIPYTLASLLK------------KRQLSINFIKVL
GSK-3_Ddis ----------DNDE--VY-LNLVLEYVPDTVYRVSRHYSM-------SKQPVPNIFVKLY
19912_Tthe ----------EEDD--VY-LNLIMEYVPSNLTKMIKYYHRKKLKQFEQREQFPNILIKLY
19923_Tthe ----------KQED--VY-LNIIMDYIPETLYRMIKYFAKK------SKGNFPNILLKLY
19924_Tthe ----------STDD--VY-LHLVMDFVPETLYKMIKYYSKK------HKGNFPNILLKYY
2636_Tthe ----------DDNK--LI-QNIVFEYMENNLEDHISKFNK-------SKKVIPEQTVKEY
5825_Tthe ----------NPDE--VY-LNIVMEYVPETLSKVIRTYRK-------SKQPFPPLLLKVF
7876_Tthe ----------KKDE--VY-LNLVMEFMNFPLSKVIRDKRK-------ANQVMRIEDIRLY
GSK3_Spur ----------KKDE--VF-LNLVLEYVPETVYRVARHYSK-------AKQTIANLYVKLY
n1163_Tthe PILTRRYSTVIPDE--VY-LNIVMEYVPETLSKVIRTYRK-------SKQPFPPLLLKVF
CC1G_03802_Ccin ----------KKDE--VY-LNLVLEYVPETVYRASRHYSK-------LKQPMPMLQIKLY
AqueK117_Aque -----------KDE--VY-LNLVLDYIPDTVYRVIRHHYK-------AKQIMPMLFIKLY
GSK_b_Smoe ----------DKDE--LY-LNLVLEYVPETVYRIAKHYNR-------MNQRMPLLYVKLY
GSK_a-2_Smoe ----------DKDE--LY-LNLVLEYVPETVYRIAKHHNR-------MNQRMPLLYVKLY
GSK_a-1_Smoe ----------DKDE--LY-LNLVLEYVPETVYRIAKHHNR-------MNQRMPLLYVKLY
GK035_Glam ----------QTNG--DF-LNILMDYYQENGYQIYKSYIR-------AGIKMPMFHIKLY
GK036_Glam ----------SPDD--LI-LYLLMDYYPETIHSIYRQYSR-------LRQHVPLLIVRLI
: :
GSK3B_Hsap MYQLFRSLAYIHS-FGICHRDIKPQNLLLDPD--TAVLKLCDFGSAKQLVRG--------
GSK3A_Hsap MYQLFRSLAYIHS-QGVCHRDIKPQNLLVDPD--TAVLKLCDFGSAKQLVRG--------
Pk34A_Dmel SYQMFRGLGYLHL-LGISHRDVKPENLLIDNQ--KMVLKLSDFGSAKLLVPQ--------
sgg_Dmel MYQLFRSLAYIHS-LGICHRDIKPQNLLLDPE--TAVLKLCDFGSAKQLLHG--------
gskt_Dmel MYQLLRSMGYLHS-LGFCHRDIKPQNMLLDSE--TGVLKLCDFGSAKQLISG--------
GSK3B_Mmus MYQLFRSLAYIHS-FGICHRDIKPQNLLLDPD--TAVLKLCDFGSAKQLVRG--------
GSK3A_Mmus MYQLFRSLAYIHS-QGVCHRDIKPQNLLVDPD--TAVLKLCDFGSAKQLVRG--------
R03D7.5_Cele TFQLFCAISHLTS-KNIVHMDIKPQNVVMDRM--AGRLKLADFGNARRLETN--------
F21F3.2_Cele TWQIFSGLKYLEE-HKVVHRDLKPVNILVDHD--TAFLKISDFGSAKIIVKG--------
C44H4.6_Cele MFQLLRGIGFLHL-HNIVHRDIKPKNLLVDES--NGILKICDFGSAKRLEKN--------
C36B1.10_Cele VWQLFRGQAHLEK-SEICHRDIKPQNLLYNAD--TGLLKISDYGSSAIESVK--------
RIM11_Scer MFQLFKSLNYLHHFANVCHRDIKPQNLLVDPE--TWSLKLCDFGSAKQLKPT--------
MRK1_Scer AYQLFKALNYLHNVPRICHRDIKPQNLLVDPT--TFSFKICDFGSAKCLKPD--------
MCK1_Scer TYQIARGMLYLHG-LGVCHRDIKPSNVLVDPE--TGVLKICDFGSAKKLEHN--------
Y106G6D.4_Cele TWQLFEGIRYLQA-HMIVHRDIKPVNILVDVD--KGTLKIADFGSAKVVLRG--------
Y106G6E.1_Cele VWQLFRGQAHLEK-ADICHRDIKPQNLLYNAE--TGLLKISDFGSSSIQSTK--------
Y18D10A.5_Cele MYQLLRSLAYIHS-IGICHRDIKPQNLLIDPE--SGVLKLCDFGSAKYLVRN--------
YOL128C_Scer TFQILRALLTLHS-MSICHGDLKPSNILIIPS--SGIAKVCDFGSAQRLDDN--------
GlkA_Ddis FYQLCQAIKHIHS-KAICHRDITPNNILLSS---KGELTLADFGSAKILESN--------
GSK-3_Ddis IYQLCRSINYIHS-LGICHRDIKPQNLLLDTS--TSTLKLCDFGSAKILIKG--------
19912_Tthe LYQAFRALAYLNG-LNIAHRDIKPSNILINHR--THQLKFCDFGSAKKLSRG--------
19923_Tthe SYQLMRSLAYIQG-LGICHRDIKPTNVLVDPR--NHALKMCDFGSAKKLNPS--------
19924_Tthe SYQMLRSLAYIHG-INICHRDIKPQNILVDPR--NHNLKMCDFGSAKKLVPG--------
2636_Tthe AYQILKGLQYIHS-KGIAHRDLKPDNILLND---DGKVKICDFGGSKYIDEK--------
5825_Tthe SYQMFRALAYLKG-IGICHRDIKPQNILCDQK--TMQLKICDFGSAKKLIKG--------
7876_Tthe AYQMFKALSYLQS-LNICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLIPN--------
GSK3_Spur MYQLFRSLAYIHS-MGICHRDIKPQNLLLNPE--TAVLKLCDFGSAKVLVRG--------
n1163_Tthe SYQMFRALAYLKG-IGICHRDIKPQNILCDQK--TMQLKICDFGSAKKLIKGKLDILFVS
CC1G_03802_Ccin MYQLLRSLAYIHS-VGICHRDIKPQNLLLNPS--TGVLKLCDFGSAKILVAG--------
AqueK117_Aque MYQLFRALGYIHA-NGVCHRDIKPQNLLLNPE--TGVLKLCDFGSAKVLVRG--------
GSK_b_Smoe TYQICRALTYIHGGMGVCHRDIKPQNLLVNPH--THQLKLCDFGSAKVLVKG--------
GSK_a-2_Smoe TYQICRSLAYIHGGIGVCHRDIKPQNLLVNPH--THQLKLCDFGSAKVLVKG--------
GSK_a-1_Smoe TYQICRSLAYIHGGIGVCHRDIKPQNLLVNPH--THQLKLCDFGSAKVLVKG--------
GK035_Glam TFQFLRGLAYMHS-FNIANRDLKPQNTLVNRE--SGRAVLCDLGSAKKLNPA--------
GK036_Glam TYQLARSLAYLHY-HNIAHRDCKPTNVLIDPL--TYRCVLCDFGSAKQLVPQ--------
:* . : . : * .* * : ..* *.:
GSK3B_Hsap ------------------------------------------------------EP-NVS
GSK3A_Hsap ------------------------------------------------------EP-NVS
Pk34A_Dmel ------------------------------------------------------EP-SIS
sgg_Dmel ------------------------------------------------------EP-NVS
gskt_Dmel ------------------------------------------------------EP-NVS
GSK3B_Mmus ------------------------------------------------------EP-NVS
GSK3A_Mmus ------------------------------------------------------EP-NVS
R03D7.5_Cele ------------------------------------------------------EKTGSA
F21F3.2_Cele ------------------------------------------------------KA-NNF
C44H4.6_Cele ------------------------------------------------------EP-NIT
C36B1.10_Cele ------------------------------------------------------TP-QQS
RIM11_Scer ------------------------------------------------------EP-NVS
MRK1_Scer ------------------------------------------------------QP-NVS
MCK1_Scer ------------------------------------------------------QP-SIS
Y106G6D.4_Cele ------------------------------------------------------SS-STS
Y106G6E.1_Cele ------------------------------------------------------SP-QQS
Y18D10A.5_Cele ------------------------------------------------------EP-NVS
YOL128C_Scer ------------------------------------------------------TE-LKT
GlkA_Ddis ------------------------------------------------------HT-SMS
GSK-3_Ddis ------------------------------------------------------ET-NVS
19912_Tthe ------------------------------------------------------ES-NIS
19923_Tthe ------------------------------------------------------ET-NIS
19924_Tthe ------------------------------------------------------ES-NIS
2636_Tthe ------------------------------------------------------GK-NTP
5825_Tthe ------------------------------------------------------EP-NVS
7876_Tthe ------------------------------------------------------EA-NIS
GSK3_Spur ------------------------------------------------------EP-NVS
n1163_Tthe YSSVVSKNLVFILISSLTAKKQIDYQQFLFKSNKKPKQLLNIQTAPFNKHQKQSEP-NVS
CC1G_03802_Ccin ------------------------------------------------------EP-NVS
AqueK117_Aque ------------------------------------------------------EP-NVS
GSK_b_Smoe ------------------------------------------------------EP-NIS
GSK_a-2_Smoe ------------------------------------------------------EP-NIS
GSK_a-1_Smoe ------------------------------------------------------EP-NIS
GK035_Glam ------------------------------------------------------EP-NIA
GK036_Glam ------------------------------------------------------EN-NVA
GSK3B_Hsap YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLG
GSK3A_Hsap YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLG
Pk34A_Dmel YICSRLYRAPELFAGYELYSCAVDIWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLG
sgg_Dmel YICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEVIKVLG
gskt_Dmel YICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGD-SGVDQIVEIVKVMG
GSK3B_Mmus YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLG
GSK3A_Mmus YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLG
R03D7.5_Cele YQVTRFYRPPELLFGCEKFTASIDIWSATCVAFELFANRVLFKGK-DTKDQIVLITGVFG
F21F3.2_Cele YQVTRFYRPPELLMKAMEYNSTVDVWSAGCIMAEMVKRHVVFPGR-DSAHQLKLYCRCFG
C44H4.6_Cele YICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLAD-SAVDILALQIKAFG
C36B1.10_Cele YHVTRYYRPPELLLGSKNYGCKIDTWSCGCVFGELLKGGIFLAGK-SAKNQAEVVFDMFG
RIM11_Scer YICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGE-SGIDQLVEIIKILG
MRK1_Scer YICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGE-SGIDQLVEIIKIMG
MCK1_Scer YICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQ-EPLLQLREIAKLLG
Y106G6D.4_Cele YQVTRFYRPPELLLDAKEYYWMVDVWSAGCCVGEMMKGKVLFPGA-SIKIMLKLIVQAIG
Y106G6E.1_Cele YHVTRYYRPPELILGSKYYGCKIDTWSCGCVFGELLKGGIILAGK-SSNNQAEVIFDMLG
Y18D10A.5_Cele YICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGD-SGVDQLVEIIKVLG
YOL128C_Scer YFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGD-SANSQLEEIAKLLG
GlkA_Ddis YICSRYYRAPELLVGCSNYTTKIDIWSIGCILAEMLIGKPLFPGT-NSNDQLGRIIEVLG
GSK-3_Ddis YICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGE-NGIDQLVEIIKVLG
19912_Tthe YICSRFYRAPELMLGASNYTTSVDVWSLGCVVAEMLLGEPLFKGN-SSLDQLVEVMKVLG
19923_Tthe YICSRYYRAPELMFMATQYTNSIDVWSVGCVIAEMVLGDPIFAGE-SSVDQLIEIIKILG
19924_Tthe YICSRCYRAPELMFQATQYTHAIDVWSVGCVIAEMVLGQPIFIGE-SSVDQLIEIIKVLG
2636_Tthe YIVSRYYRAPELILCITKYNQKIDMWSFGCILGELVTTFPLFQGK-TEGDQLFSIFKVLG
5825_Tthe YICSRYYRAPELIFGAEQYTTAIDTWSIGTVIAEMILGEPLFPGE-NAVEQLVEIIKILG
7876_Tthe YICSRYYRAPELIFKSQHYTNAIDMWSMGCVIAEMVLGEPLFPGE-NSLDQLVEIIRILG
GSK3_Spur YICSRYYRAPELIFGATDYTCDIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLG
n1163_Tthe YICSRYYRAPELIFGAEQYTTAIDTWSIGTVIAEMILGEPLFPGE-NAVEQLVEIIKILG
CC1G_03802_Ccin YICSRYYRAPELIFGATNYTTNIDIWSTGCVMAELMLGQPLFPGE-SGIDQLVEIIKVLG
AqueK117_Aque YICSRYYRAPELIFGATDYTVNIDIWSAGCVFAELLLGQPIFPGD-SGVDQLVEIIKILG
GSK_b_Smoe YICSRYYRAPELIFGATDYTTAIDIWSTGCVLAELLLGQPLFPGE-SGVDQLVEIIKVLG
GSK_a-2_Smoe YICSRYYRAPELIFGATEYTTAIDIWSMGCVLAELLLGQPLFPGE-SGVDQLVEIIKVLG
GSK_a-1_Smoe YICSRYYRAPELIFGATEYTTAIDIWSMGCVLAELLLGQPLFPGE-SGVDQLVEIIKVLG
GK035_Glam YICSRYYRAPELIFGSRYYTTVIDIWSFGCVVAEMIIGKPIYAGS-SPLDQIIEIIKILG
GK036_Glam YICSRFYRAPELVIGNQNYTCAIDIWSFGCIMAEILLGQPLFPGD-SSIDQLVEIVRVLG
* :* **.***. : :* *. *:. . . :*
GSK3B_Hsap TPTREQIREMNPNYT--EFKF------------------------PQ------IKA----
GSK3A_Hsap TPTREQIREMNPNYT--EFKF------------------------PQ------IKA----
Pk34A_Dmel TDGLERAPEILSKCG--NSLH------------------------PR------TTR----
sgg_Dmel TPTREQIREMNPNYT--EFKF------------------------PQ------IKS----
gskt_Dmel TPTSEQLHDMNPHYK--QFKL------------------------PE------LKP----
GSK3B_Mmus TPTREQIREMNPNYT--EFKF------------------------PQ------IKA----
GSK3A_Mmus TPTREQIREMNPNYT--EFKF------------------------PQ------IKA----
R03D7.5_Cele YPTDDDIKSIGVKRP--RVARKDARGIETVKIKEKTNKTKKEAKQSTLVHEKYTRARAMS
F21F3.2_Cele APNEQDISAMKGEKL--EKEYWKF-----------------------------TKG----
C44H4.6_Cele TPSKEDMAKWNYEYV--HIPY------------------------DT------ITG----
C36B1.10_Cele VPTAEDVSSMNVSNT--KYKE-------------------------I------IQS----
RIM11_Scer TPSKQEICSMNPNYM--EHKF------------------------PQ------IKP----
MRK1_Scer IPTKDEISGMNPNYE--DHVF------------------------PN------IKP----
MCK1_Scer PPDKRFIFFSNPAYD--GPLFSK---P----------------LFSG------SSQ----
Y106G6D.4_Cele LPSARDLDYMKVSSM--IDQQSA------------------------------VKV----
Y106G6E.1_Cele YPTDSDVSSMKVSST--KLQE-------------------------V------LDS----
Y18D10A.5_Cele TPTREQIQSMNPNYK--EFKF------------------------PQ------IKA----
YOL128C_Scer RFPKSSIKNSQELQ----DSLND---Q----------------KFK--------------
GlkA_Ddis SPTKDDMEAMKPSKP--YHL-----------------------QLPN------INP----
GSK-3_Ddis TPTKEQIHAMNPYYT--SFKF------------------------PE------IKA----
19912_Tthe APSPEQIREMNPEHK--LLKY------------------------PP------INK----
19923_Tthe TPTLQQ--HMNPDHQ--PTQM------------------------PK------IKP----
19924_Tthe TPTQQQIFAMNPDHQ--GTKM------------------------PN------IKP----
2636_Tthe SPTKEEFQKFSERVPFDKKIFD---------------------EFQT------YEP----
5825_Tthe TPTKEQVQKMNPQHN--QFNF------------------------PS------IKP----
7876_Tthe TPTRQQILMMNPTSQ--EFRF------------------------PQ------IKS----
GSK3_Spur TPSRDQIKEMNPNYT--EFKF------------------------PQ------IKP----
n1163_Tthe TPTKEQVQKMNPQHN--QFNF------------------------PS------IKP----
CC1G_03802_Ccin TPSREQIKTMNPNYM--EHKF------------------------PQ------IKP----
AqueK117_Aque TPTKEQIRQMNPNYT--EFKF------------------------PQ------IKA----
GSK_b_Smoe TPTREEIKCMNPNYT--EFKF------------------------PQ------IKA----
GSK_a-2_Smoe TPTREEIKCMNPNYT--EFKF------------------------PQ------IKA----
GSK_a-1_Smoe TPTREEIKCMNPNYT--EFKF------------------------PQ------IKA----
GK035_Glam PPSLKELKEMNPTLK--EYAF------------------------PT------IRT----
GK036_Glam SPTAEEFLAMNPTLK--SVKF------------------------KD------VKR----
GSK3B_Hsap ----HP----------------------------WTKDSSGTGHFTSGVRVFR-------
GSK3A_Hsap ----HP----------------------------WTK-------------VFK-------
Pk34A_Dmel ----PS----------------------------WNY-------------LLN-------
sgg_Dmel ----HP----------------------------WQK-------------VFR-------
gskt_Dmel ----HP----------------------------WSK-------------VFR-------
GSK3B_Mmus ----HP----------------------------WTKDSPGAGHFTPGVRVFR-------
GSK3A_Mmus ----HP----------------------------WTK-------------VFK-------
R03D7.5_Cele RSTENK----------------------------LAP-------------FTS-------
F21F3.2_Cele ----FG----------------------------LQR-------------LVN-------
C44H4.6_Cele ----VG----------------------------IQK-------------FIG-------
C36B1.10_Cele ----YEPDTSKRTADLAYLYNQTASFQRDRRSTVYNT-------------KID-------
RIM11_Scer ----IP----------------------------LSR-------------VFK-------
MRK1_Scer ----IT----------------------------LAE-------------IFK-------
MCK1_Scer ----QR----------------------------FEK-------------YFG-------
Y106G6D.4_Cele ----IG----------------------------LKE-------------VLG-------
Y106G6E.1_Cele ----YEYNKSKTTADLTYLYTQTVIYQKDRRTTVYNT-------------KIE-------
Y18D10A.5_Cele ----HP----------------------------WNK-------------VFR-------
YOL128C_Scer -----K----------------------------FMH-------------WFP-------
GlkA_Ddis ----KF----------------------------FES--------------LH-------
GSK-3_Ddis ----NP----------------------------WPR-------------VFK-------
19912_Tthe ----MP----------------------------LSK-------------ICQ-------
19923_Tthe ----TP----------------------------WSK-------------VFK-------
19924_Tthe ----TP----------------------------WTK-------------VFQ-------
2636_Tthe ----QN----------------------------LRK-------------MFF-------
5825_Tthe ----TS----------------------------WTK-------------IF--------
7876_Tthe ----YS----------------------------WSK-------------VFEKSLQ---
GSK3_Spur ----HP----------------------------WNK-------------VFR-------
n1163_Tthe ----TS----------------------------WTK-------------LIKQISTVIN
CC1G_03802_Ccin ----HP----------------------------FSK-------------VFR-------
AqueK117_Aque ----HA----------------------------WNK-------------VFR-------
GSK_b_Smoe ----HP----------------------------WHK-------------VFH-------
GSK_a-2_Smoe ----HP----------------------------WHK-------------VFH-------
GSK_a-1_Smoe ----HP----------------------------WHK-------------VFH-------
GK035_Glam ----TP----------------------------MSD-------------VLG-------
GK036_Glam ----YP----------------------------FSK-------------IFR-------
GSK3B_Hsap ----------------P-RTPP--EAIALCSRLLEYTPTARLTPLEACAHSFFDELRD-P
GSK3A_Hsap ----------------S-RTPP--EAIALCSSLLEYTPSSRLSPLEACAHSFFDELRC-L
Pk34A_Dmel ----------------T-AVPQ--DLCGLLNSCFIYEAAARISPMMACSHGSYDELRI-M
sgg_Dmel ----------------I-RTPT--EAINLVSLLLEYTPSARITPLKACAHPFFDELRM-E
gskt_Dmel ----------------I-RTPA--EAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDP
GSK3B_Mmus ----------------P-RTPP--EAIALCSRLLEYTPTARLTPLEACAHSFFDELRD-P
GSK3A_Mmus ----------------SSKTPP--EAIALCSSLLEYTPSSRLSPLEACAHSFFDELRR-L
R03D7.5_Cele -----------------KMLDS--EIYDFMKATLKIDPKKRKSAIDVLKMPLFDILRS-S
F21F3.2_Cele -----------------D-ISP--DQLQFIKRILVYAPEKRLRGKQLLQDDFFRPLFK-A
C44H4.6_Cele ----------------R-KLSL--STLELLNSLMKMDPKLRIKPYEALTLPYFDDLRD-P
C36B1.10_Cele ----------------Y-SDMK--DSVELLRQVLVYNPSRRLCGIEFLTNPFFTVLFN-E
RIM11_Scer ----------------K-E-DD--QTVEFLADVLKYDPLERFNALQCLCSPYFDELKL-D
MRK1_Scer ----------------A-E-DP--DTLDLLTKTLKYHPCERLVPLQCLLSSYFDETKR-C
MCK1_Scer -----------------H-SGP--DGIDLLMKILVYEPQQRLSPRRILAHQFFNELRN-D
Y106G6D.4_Cele -----------------T-ENQ--EWADFLGAILRYRPRERLHGPKLLSHPFFDLIFT-P
Y106G6E.1_Cele ----------------Q-DDMK--ESVAVLLQILVYNPNKRLSGIEILTHPYFNVLFN-E
Y18D10A.5_Cele ----------------V-HTPA--EAIDLISKIIEYTPTSRPTPQAACQHAFFDELRN-P
YOL128C_Scer -----------------S-IEF--FDVEFLLKVLTYDATERCDARQLMAHEFFDALRN-E
GlkA_Ddis ----------------NV-EDK--TVVDLLSKIFIFDPVKRASIDEIIAHPFLRDVNIN-
GSK-3_Ddis ----------------AKDVPA--ESIDLISKILLYDPSSRLKPVEICAHPFFDELRD-P
19912_Tthe ----------------N-KCQSMNHLKGLSLQKLYYIPILMN-----------------Q
19923_Tthe ----------------NCKVDP--LAIDLISKVLVYSPQLRLKPLEALAHPFFDELRN-P
19924_Tthe ----------------NCRIDP--LAIDLISKILVYNPEKRLKPLEALLHPFFEELRN-P
2636_Tthe ----------------YIKDID--NLMDLITKCLQYLPENRITADEALQHPFFKGLEE--
5825_Tthe ---------------AKQKPDP--MLIDLISRLLVFVPTDRPTPLETLLHPYFNELRS-E
7876_Tthe -----------KVSEDEKQKFN--QLMDLISRVLVYAPSERPSPLQALAHPFFDELRI-E
GSK3_Spur ----------------A-RTPA--DAIQLCSRLLEYTPKSRIKPLEACAHQFFSELRE-P
n1163_Tthe KYSNKKQQQNANIF-AKQKPDP--MLIDLISRLLVFVPTDRPTPLETLLHPYFNELRS-E
CC1G_03802_Ccin ----------------P-RTAP--EAIDLVSKLLEYTPGARLSAVEAMVHPFFDELRA-E
AqueK117_Aque ----------------P-RTPP--EAIDLVSRLLEYTPTMRITTLDSCAHSFFDELRQ-P
GSK_b_Smoe ----------------K-RMPP--EAVDLVSRLLQYSPSLRCNALEALVHPFFDELRD-P
GSK_a-2_Smoe ----------------K-RMPP--EAVDLVSRLLQYSPNLRCSSLEALAHPFFDELRD-P
GSK_a-1_Smoe ----------------K-RMPP--EAVDLVSRLLQYSPNLRCSSLEALAHPFFDELRD-P
GK035_Glam ----------------T-K-DP--VVLDFFARCFKYSPNERITAYEALAHPFYDDLRA-R
GK036_Glam ----------------S-KAHT--DAVDLLTKVLVYDPKKRPTAMEILAHPFYDILRD-P
. : .
GSK3B_Hsap N---VKLPNGRD----TPA-LFNFTTQ-ELS---------S-N--PP------LAT----
GSK3A_Hsap G---TQLPNNRP----LPP-LFNFSAG-ELS---------I-Q--PS------LNA----
Pk34A_Dmel DAMALPMPNGNP----LPP-LFDFNSL-EMG---------T-D--PK------LWV----
sgg_Dmel GN--HTLPNGRD----MPP-LFNFTEH-ELS---------I-Q--PS------LVP----
gskt_Dmel H---QQLPNGRS----LPP-LFNFTDY-EKT---------I-E--PD------TMP----
GSK3B_Mmus N---VKLPNGRD----TPA-LFNFTTQ-ELS---------S-N--PP------LAT----
GSK3A_Mmus G---AQLPNDRP----LPP-LFNFSPG-ELS---------I-Q--PS------LNA----
R03D7.5_Cele PP--KKRSNGVE----MPN-LASYTEM-HHK---------R-E--PE------T------
F21F3.2_Cele G---AVRHNGQK----ISD-VITAADY-KRA---------A-E--NEESSACRLAQLVKT
C44H4.6_Cele H---YKLPSGAP----IPP-LFDWLER-EYI---------A-N--HE------IIK----
C36B1.10_Cele KT---VRFNKKK----IQC-VSAVDLQ-AVK-----------------------------
RIM11_Scer D---GKINQITT----DLK-LLEFDENVEL---------GH-L-----------------
MRK1_Scer D---TDTYVKAQ----NLR-IFDFDVETEL---------GH-V--PL------VER----
MCK1_Scer D---TFLPRGFTEPIKLPN-LFDFNDF-ELQ---------I-L--GE------FAD----
Y106G6D.4_Cele K---CTLSNGLL----VSQ-VITLDDY-KTA---------Q-K--NDSTSGKQYAAAILR
Y106G6E.1_Cele KT---VRFNKKK----ILC-LSAVDLQ-SVK-----------------------------
Y18D10A.5_Cele D---ARLPSGRP----LPT-LEMDGPM-GTG-----------------------------
YOL128C_Scer T---YFLPRGSSMPVHLPD-LFNFSAS-EKR---------A-L--GE------YYN----
GlkA_Ddis S---LELFDE----M---K-CFSVSGN-GKS--------SL-TTNST------SSS----
GSK-3_Ddis K---TCLPDGKP----LPP-LFNFTIA-EQT--------SI-G--PK------LAK----
19912_Tthe -E--QSI-AGQM----ER-DFHLYST-F---------Q----------------------
19923_Tthe L---CRI-NGQK----LPE-LFNFTQI-IIQILFKLVEVNGYP--DE------LIN----
19924_Tthe K---CRI-NGKP----LDN-LFNFTEA-EIG---------P-N--EE------LLQ----
2636_Tthe ------------------------------------------------------------
5825_Tthe K---FYE-QYTK----QID-LFNFSPE-E---------LKS-Q--PQ------LAS----
7876_Tthe E---KKY-RQT-----QLY-LFDFPEA-KE--------QEY-Q--KQ------IEQ----
GSK3_Spur G---TKLPNGRE----LPP-LFNFSAS-ELV---------S-K--PS------LRT----
n1163_Tthe K---FYE-QYTK----QID-LFNFSPE-E---------LKS-Q--PQ------LAS----
CC1G_03802_Ccin G---AKMPNGKE----FPR-LFDFTRE-ELS---------V-R--PD------LIR----
AqueK117_Aque G---ANMPNGRD----FPP-LFNFSQQ-ELS---------I-C--PS------LES----
GSK_b_Smoe S---TRLPNGRP----LPA-LFNFKPL-ELK--------GA-S--QE------LLE----
GSK_a-2_Smoe N---TRLPNGRP----LPP-LYNFKQL-ELK--------GA-S--PE------LLN----
GSK_a-1_Smoe N---TRLPNGRP----LPP-LYNFKQL-ELK--------GA-S--PE------LLN----
GK035_Glam D---API--SKD----L-K-LFEFSEY-ERK--------AM-S--PE------LLS----
GK036_Glam D---TLLPNGER----LPAFLFEFTEE-ERK--------AA-G--PE------LMA----
GSK3B_Hsap ------------------------ILI-PPHA----------------------------
GSK3A_Hsap ------------------------ILI-PPHL----------------------------
Pk34A_Dmel ------------------------NLL-PIHL----------------------------
sgg_Dmel ------------------------QLL-PKHL----------------------------
gskt_Dmel ------------------------LLL-PRAQ----------------------------
GSK3B_Mmus ------------------------ILI-PPHA----------------------------
GSK3A_Mmus ------------------------ILI-PPHL----------------------------
R03D7.5_Cele ------------------------EVV-ADIQ----------------------------
F21F3.2_Cele DNKDLGIPYCEKSNSYENVYARRSTLI-PKEQ----------------------------
C44H4.6_Cele ------------------------DIF-PRSE----------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer --------------------------S-PDEL----------------------------
MRK1_Scer ------------------------PAI-EERL----------------------------
MCK1_Scer ------------------------KIK-P-------------------------------
Y106G6D.4_Cele HEIRF---------------SLKAPIVHPPAPPAPPVVPMIDMISCRFLIFLSLLVTVFS
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------LIV-P-------------------------------
GlkA_Ddis ------------------------STT-AN-M----------------------------
GSK-3_Ddis ------------------------TLI-PSHA----------------------------
19912_Tthe -----------------------KLLT-PKWY----------------------------
19923_Tthe ------------------------KLI-PDWY----------------------------
19924_Tthe ------------------------RLI-PDWY----------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------QLI-PQWY----------------------------
7876_Tthe -----------------------LKLI-PNGY----------------------------
GSK3_Spur ------------------------VLI-PPHA----------------------------
n1163_Tthe ------------------------QLI-PQWY----------------------------
CC1G_03802_Ccin ------------------------KLV-PPHA----------------------------
AqueK117_Aque ------------------------KLV-PPHY----------------------------
GSK_b_Smoe ------------------------RLI-PEHA----------------------------
GSK_a-2_Smoe ------------------------RLV-PEHA----------------------------
GSK_a-1_Smoe ------------------------RLV-PEHA----------------------------
GK035_Glam ------------------------KIR---------------------------------
GK036_Glam ------------------------VLT-KNR-----------------------------
GSK3B_Hsap ----------RIQAAAS-T------------P-----------------T----------
GSK3A_Hsap ----------RSPAGTT-T------------L----------------------------
Pk34A_Dmel ----------SSM-----------------------------------------------
sgg_Dmel ----------QNASGPG-G------------NRPSAGGAASIAASGSTSV----------
gskt_Dmel ----------GSSTTKEPS------------A-----------------A--HRNRNTAG
GSK3B_Mmus ----------RIQAAAS-P------------P-----------------A----------
GSK3A_Mmus ----------RSPAGPA-S------------P-----------------L----------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ----------KMARDNK-S------------K-----------------EDSS-------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele -----------SG-----------------------------------------------
RIM11_Scer ----------S-------------------------------------------------
MRK1_Scer ----------K-------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele LECYTGFTYLKAQSVGT-S------------K-----------------ETCP-------
Y106G6E.1_Cele -----------SG-----------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ----------TSLASSS-SNNKTTCSETYLSR----------------------------
GSK-3_Ddis ----------MNQIELP-S------------P-----------------L----------
19912_Tthe ----------QLLKQ---------------------------------------------
19923_Tthe ----------SQMCAGV-------------------------------------------
19924_Tthe ----------VQQL----------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ----------TSRREKE-S------------KL----------------I----NNSKQA
7876_Tthe ------------------------------------------------------------
GSK3_Spur ----------SHSQNSS-S------------T-----------------T----------
n1163_Tthe ----------TSRREKE-S------------KL----------------I----NNSKQA
CC1G_03802_Ccin ----------EPELASR-S------------I-----------------A----------
AqueK117_Aque ----------HESLSSG-S------------SG----------------P----------
GSK_b_Smoe ----------RKQ-----------------------------------------------
GSK_a-2_Smoe ----------RKQ-----------------------------------------------
GSK_a-1_Smoe ----------RKQ-----------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ----------------------------------------------------NA-----T
GSK3A_Hsap --------------------------------------------------TPSS-----Q
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel -------------------------------------SSTGSGASVEGSAQPQS-----Q
gskt_Dmel E-ESPRKTED--------------------------------------SQKPAT-----A
GSK3B_Mmus ----------------------------------------------------NA-----T
GSK3A_Mmus ----------------------------------------------TTSYNPSS-----Q
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele --------------------------------------------------DDRR------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele --------------------------------------------------SPND-----Y
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis --------------------------------------------------LPTS------
GSK-3_Ddis ---------FPNLAISSSNQS-SSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSP
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe EQQQSQL--VNQLT-NEFNQKMDISNSQ----KNING-----------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur --------------------------------------------------VPH-------
n1163_Tthe EQQQSQL--VNQLT-NEFNQKMDISNSQ----KNING-----------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque --------------------------------------------------PPQG-----H
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ---AA---SDAN------------------------------------------------
GSK3A_Hsap ---AL---TETP------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ---GTA--AAAG----------------SGSGGATAGTGGASAGGPGSGNNSSSGGASGA
gskt_Dmel ---AL---SKSPGPSGKALESPPGFLQHDLGNGDHVAVGTMPMEPLTLEQNHFAAESYAV
GSK3B_Mmus ---AA---SDTN------------------------------------------------
GSK3A_Mmus ---AL---TEAQ------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele VAPSS---GEAP------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele CYNMT---ADLT------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ---AITSSSNLK------------------------------------------------
GSK-3_Ddis ---ST---TNTT------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe -------------NFG--------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe -------------NFG--------------------------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ---AS---NDVH------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap ------------------------------T-----------------------------
GSK3A_Hsap ------------------------------T-----------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel PSAVAAGGANAAVAGGAGGGGGAGAATAAAT-----------------------------
gskt_Dmel GEDAEDNLEEDVGDENDYDYDDGGQCNSTYI-----------------------------
GSK3B_Mmus ------------------------------A-----------------------------
GSK3A_Mmus ------------------------------T-----------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------SA----PGKRSES------NK---------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------SLNNVKKGGCSSTRCILARNKCMTQSIGGT
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------S-----------------------------
GSK-3_Ddis ------------------------------S-----------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe -----------------------G---SMMS-----------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe -----------------------G---SMMS-----------------------------
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ---------------------------TTVV-----------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap --------------GD-------R--GQTNNAASASASNST
GSK3A_Hsap --------------SS-------D--WQS-TDATPTLTNSS
Pk34A_Dmel ----------------------------EDKYSVVEAFEAV
sgg_Dmel --------------AT-------G--AIGATNAGGANVTDS
gskt_Dmel ---SDD--------MD-------E--ASESDDDDFEEEDEN
GSK3B_Mmus --------------GD-------R--GQTNNAASASASNST
GSK3A_Mmus --------------GQ-------D--WQPSDATTATLASSS
R03D7.5_Cele ---------------------TTE--KAEKESDSTNEELED
F21F3.2_Cele --------TAAIAKKS-TMKSVMN--------APPPRQKPE
C44H4.6_Cele ---------------------------------EGDKVECL
C36B1.10_Cele ----------------------------DVTLTNESVEHST
RIM11_Scer ------------------------------SVKKKLYPKSK
MRK1_Scer ------------------------------HF-VSAPSSSL
MCK1_Scer ------------------------------------TKVAE
Y106G6D.4_Cele QIQFCCCNTGDLCNSKLTNMSFFE--KTKQRAKDFLDMLRG
Y106G6E.1_Cele ----------------------------DTTLTNESVEQTS
Y18D10A.5_Cele ---------------------------EVSTTSGDVAGPSA
YOL128C_Scer --------------------------------------SLD
GlkA_Ddis ---IDNSNNGKSSSSS-------NNIPSLNNSNNGVITNTI
GSK-3_Ddis --------------ST-------T--NNTTTTTTTTTTSNH
19912_Tthe -----------------------------AGEDKNHFNQEY
19923_Tthe --------------------------------DNRSSDDSN
19924_Tthe ----------------------------------TEAQNQY
2636_Tthe --------------------------------------KYP
5825_Tthe --------------SS-------Q--SNPNMGNYQKNYQYH
7876_Tthe -----------------------------------SKKSYS
GSK3_Spur -----------------------D---APETSTSATASSAT
n1163_Tthe --------------SS-------Q--SNPNMGNYQKNYQYH
CC1G_03802_Ccin --------------LD----------TFVPIPLEQMKISLD
AqueK117_Aque --------------MT-------T--PDPTSELMGPNATGQ
GSK_b_Smoe -----------------------------------VPFLAL
GSK_a-2_Smoe -----------------------------------VPFLAL
GSK_a-1_Smoe -----------------------------------VPFLAL
GK035_Glam ---------------------------------------PQ
GK036_Glam --------------------------------EQFNILSSH