LRRK2_Hsap -------------GDGSFGSV-YRAAYEG---------EEVAVKIFNKH-----------
LRRK1_Hsap E----DE--GSVLGQGGSGTVIYRARYQG---------QPVAVKRFHIKKF-KNF-----
CG5483_Dmel I----IK--GSLLGRGAFGFV-FKANCKSA---------LMAFKVAVG------------
LRRK2_Mmus -------------GDGSFGSV-YRAAYEG---------EEVAVKIFNKH-----------
LRRK1_Mmus E----GE--NSILGQGGSGTVIYQARYQG---------QPVAVKRFHIKKF-KNS-----
T27C10.5_Cele L----KR--SRMLGRGAFGFV-FRATVRQPNG----ELCEVAQKMLEPVDP-GPG-----
GbpC_Ddis V----KI--NKEVGRGAFGIV-YEAEWMS---------EWIALKKLLLPSS-TDT-----
Pats1_Ddis L----MI--EELIGEGGAALV-YRARWQG---------QTVAVKKLKTIEN-LDS-----
QkgA_Ddis I----LY--ERQIGEGGFGLI-HKGKLISN-------KSDIAIKSLILCNS-NNN-----
QkgA_C2d_Ddis I----LY--ERQIGEGGFGLI-HKGKLISN-------KSDIAIKSLILCNS-NNN-----
Roco10_Ddis V----FN--APLLGA----------------------------------D----------
Roco11_Ddis V----VC--EEQIGVGGFGLV-HKGKLILQD-----KSLVVAIKSYIVGNS-S-------
Roco4_Ddis I----EY--EKQIGKGGFGLV-HKGRLVKD-------KSVVAIKSLILGDS-E-------
Roco5_Ddis L----EI--IEKVGEGGFGIV-YKGKLRG---------QLVAIKQITIDSG---------
Roco6_Ddis I----EFESPKLIGRGASGKI-YRANLND---------TMVAVKQLEVVG----------
Roco7_Ddis L----KF--GPQLGSGSYANV-YRGIWNG---------SEVAIKVLNFDD----------
Roco8_Ddis L----IY--QEEIGVGGFSRV-YKGIYKN---------NTVAIKQFNFERM-DL--IDS-
Roco9_Ddis FKEVELD--PNPIGEGGTATV-YKGKWRQ---------SDVAIKLLKTDVV---------
LRRKd_Spur M----VS--GQSLGQGGFGEV-FRAKFRG---------ETVAAKTMLPSRLLKNRMFSSA
LRRKc_Spur M----VS--GQSLGQGGFGEV-FRAKFRG---------ETVAAKTMFPSRLLKNQMYSSP
LRRKb_Spur Q----RA--ENLLGDGSFGSV-YKGTYRD---------KPVAVKVFSKGGE---------
LRRKa_Spur L----EI--QRLLGSGTFGLV-FQGVMARASE----HRRPIAAKMLQPYPP-GQG-----
AqueK485_Aque ------------------------------------------------------------
AqueK486_Aque E----DK--DSLLGEGGFGKV-YRGKCRG---------KSVAIKKYLTR-----------
AqueK487_Aque I----SK--LEVLGSGGFGSV-YKGLIEEGQ-------VTVAIKEFSSIAG-KME-----
AqueK488_Aque ------------VGCGCFGVV-YHKRLQLEQYDP-DISREVAVKEFRSSDM---------
AqueK489_Aque S-----------------------------------------------------------
AqueK490_Aque T----VK--KHLF-----------------------------------SE----------
AqueK491_Aque V----DR--GKFVASGSFGEI-YHGAIYPHLSASDDEGREVAIKIDKQD-R---------
AqueK492_Aque E----DK--DSLLGEGGFGKV-YRGKFHG---------KSVAIKKYLTR-----------
AqueK493_Aque E----DK--DSLLGEGGFGKV-YRGKFRS---------KSVAIKKYLMR-----------
AqueK494_Aque -----------VLGKGGFGEV-FKALYNE---------KSVAIKVFSPRVA-E-------
AqueK495_Aque -------------------QV-YKGTYYNQ---------PVAIKVFPIDSS---------
AqueK496_Aque I----LE--KEVLGKGGYGFV-CTGELKGPTGS---PPELVAVKVFLTNLE-GKI-----
AqueK497_Aque K----DL--STRLGRGGAGAV-YKGKYRNV---------PVAVKEFLTQSQ-ADA-----
AqueK498_Aque V----LK--KERLGRGAFATV-YHAQIKRKLPNGQIHFEDVAIKALGNKGE-D-------
LRRK2_Hsap ------------------------------------------------------------
LRRK1_Hsap -------------------------------------------------AN---------
CG5483_Dmel ------------------------------------------------------------
LRRK2_Mmus ------------------------------------------------------------
LRRK1_Mmus -------------------------------------------------AN---------
T27C10.5_Cele -----------------------------------------------G-RPSALA-----
GbpC_Ddis -----------------------------------------------TNLNGNGE-----
Pats1_Ddis ------------------------------------------------------------
QkgA_Ddis -----------------------------------------------NNSNNNNN-----
QkgA_C2d_Ddis -----------------------------------------------NNSNNNNN-----
Roco10_Ddis ------------------------------------------------------------
Roco11_Ddis ------------------------------------------------------------
Roco4_Ddis ------------------------------------------------------------
Roco5_Ddis ------------------------------------------------------------
Roco6_Ddis ------------------------------------------------------------
Roco7_Ddis ------------------------------------------------------------
Roco8_Ddis ---------TSFNNLNSLTISPSNSSLSISLSSSTSSLSPPIVNNNNNNNNLNNNLNNLN
Roco9_Ddis ------------------------------------------------------------
LRRKd_Spur SEGYASCAST-----------------------------------SSSTSNRTGE-----
LRRKc_Spur SEGYASCAST-----------------------------------PSSTSNMTGE-----
LRRKb_Spur ------------------------------------------------------------
LRRKa_Spur -----------------------------------------------A-GNTDRR-----
AqueK485_Aque ------------------------------------------------------------
AqueK486_Aque ------------------------------------------------------------
AqueK487_Aque ------------------------------------------------------------
AqueK488_Aque ------------------------------------------------------------
AqueK489_Aque ------------------------------------------------------------
AqueK490_Aque ------------------------------------------------------------
AqueK491_Aque ------------------------------------------------------------
AqueK492_Aque ------------------------------------------------------------
AqueK493_Aque ------------------------------------------------------------
AqueK494_Aque ------------------------------------------------------------
AqueK495_Aque ------------------------------------------------------------
AqueK496_Aque -----------------------------------------------D-SLS--------
AqueK497_Aque -----------------------------------------------F-QDEDEL-----
AqueK498_Aque -----------------------------------------------L-DDDDDE-----
LRRK2_Hsap ------------------------------------------------------------
LRRK1_Hsap ------------------------------------------------------------
CG5483_Dmel ------------------------------------------------------------
LRRK2_Mmus ------------------------------------------------------------
LRRK1_Mmus ------------------------------------------------------------
T27C10.5_Cele ------------------------------------------------------------
GbpC_Ddis ------------------------------------------------------------
Pats1_Ddis ------------------------------------------------------------
QkgA_Ddis ------------------------------------------------------------
QkgA_C2d_Ddis ------------------------------------------------------------
Roco10_Ddis ------------------------------------------------------------
Roco11_Ddis ------------------------------------------------------------
Roco4_Ddis ------------------------------------------------------------
Roco5_Ddis ------------------------------------------------------------
Roco6_Ddis ------------------------------------------------------------
Roco7_Ddis ------------------------------------------------------------
Roco8_Ddis NNNKLYIQQQQQTQQNQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNQQQPKILQ
Roco9_Ddis ------------------------------------------------------------
LRRKd_Spur ------------------------------------------------------------
LRRKc_Spur ------------------------------------------------------------
LRRKb_Spur ------------------------------------------------------------
LRRKa_Spur ------------------------------------------------------------
AqueK485_Aque ------------------------------------------------------------
AqueK486_Aque ------------------------------------------------------------
AqueK487_Aque ------------------------------------------------------------
AqueK488_Aque ------------------------------------------------------------
AqueK489_Aque ------------------------------------------------------------
AqueK490_Aque ------------------------------------------------------------
AqueK491_Aque ------------------------------------------------------------
AqueK492_Aque ------------------------------------------------------------
AqueK493_Aque ------------------------------------------------------------
AqueK494_Aque ------------------------------------------------------------
AqueK495_Aque ------------------------------------------------------------
AqueK496_Aque ------------------------------------------------------------
AqueK497_Aque ------------------------------------------------------------
AqueK498_Aque ------------------------------------------------------------
LRRK2_Hsap -------------------------------------------------TSLRLLRQELV
LRRK1_Hsap ------------VPA-----------------D--TMLRHL--RATDAMKNFSEFRQEAS
CG5483_Dmel ------------------------------------KWDRD--PLQHSCKAYCTARQELA
LRRK2_Mmus -------------------------------------------------TSLRLLRQELV
LRRK1_Mmus ------------APA-----------------D--TMLRHL--RAMDAMKNFSDFRQEAS
T27C10.5_Cele ----------AYKAA-----------------A--DKWKRD--SMEFACRAYCTSRQELS
GbpC_Ddis ----------VM-VY-----------------D----DPDQ--LIEDRLRVFREFRHEVY
Pats1_Ddis -------------------------------------PIEI--NDISLSKAFNEFRRECW
QkgA_Ddis ----------SN-NS-----------------N--NFKNNN--NEDEFIEKFQEFQHEVF
QkgA_C2d_Ddis ----------SN-NS-----------------N--NFKNNN--NEDEFIEKFQEFQHEVF
Roco10_Ddis -------------------------------------------FQNNCARILSSFRHEAL
Roco11_Ddis --------------------------------------------ASDIIRKFQEFHHEMY
Roco4_Ddis -------------------------------------------GETEMIEKFQEFQREVF
Roco5_Ddis -------------------------------------------QAEAASEIYREFRREVW
Roco6_Ddis ---------------------------------------------EDAPRIFSEFRREIH
Roco7_Ddis -------------------------------------------GHANTTEKYREFRNEAH
Roco8_Ddis RNLSTSSLSSNSSQG-----------------E--DSMNQI---SSGKLNAINEFRREVW
Roco9_Ddis --------------------------------------------GSDFSKVFAEYRREIF
LRRKd_Spur ----------STSTE----------------------NDSL--EAAMLMESFHKLRNEVA
LRRKc_Spur ----------STSTE-----------------N--DSCDSL--EAAMLMDSFHKLRNEVA
LRRKb_Spur ------------------------------------------------SHPHRLLRQEVT
LRRKa_Spur ----------RYDND-----------------N--TKWHRD--PLRFSCEAYRTARKELS
AqueK485_Aque -----------------------------------------------------KLYQDFD
AqueK486_Aque -----------------------------------------------TEEAFNELRSEAK
AqueK487_Aque -------------------------------------EDTLIGHELNAWDIYINGSREAR
AqueK488_Aque --------------------------------------DYD--AELEVVKSYADMRYELN
AqueK489_Aque ------------------------------------------------------------
AqueK490_Aque --------------------------------------------SKSYSVPLSAMRQELE
AqueK491_Aque --------------------------------------KHF--NMETAAKAYTEIRAEVA
AqueK492_Aque -----------------------------------------------QEEAFNELRHEAK
AqueK493_Aque -----------------------------------------------QEEAFNELCHEAK
AqueK494_Aque ---------------------------------------------LHSTTPNQLIRQEVS
AqueK495_Aque ---------------------------------------------ANHFTVLRLHRSELS
AqueK496_Aque -------------SA-----------------E--LLEEAA--KDSQLRSAYKEIRQEVN
AqueK497_Aque ----------PPGGI-----------------HTYHDDDSI--SSGEALFLYRDMRQEVT
AqueK498_Aque ------------DISLDEEEERPGGDDEYDGENARE-PPPI--QRSAIISGFNNLKKELS
LRRK2_Hsap VLCHLHHPSLISLLAAGIRPR-MLVMELASKGSLDRL-----LQQDK-------------
LRRK1_Hsap MLHALQHPCIVALIGISIHPL-CFALELAPLSSLNTV-----LSENARDSS---------
CG5483_Dmel VLLTLKHPNIVPLVGICIKPL-ALVLELAPLGGLDAL-----LRHYRRSG----------
LRRK2_Mmus VLCHLHHPSLISLLAAGIRPR-MLVMELASKGSLDRL-----LQQDK-------------
LRRK1_Mmus MLHALQHPCIVSLIGISIHPL-CFALELAPLGSLNTV-----LSENAKDSS---------
T27C10.5_Cele LLSRMKHPNVIGLVGVCTFPL-SLVVELAPLGALNQL-----LGSHRKAG----------
GbpC_Ddis YMSGLNHPNVMKISGFCIQPL-CMALEYVRYGSLYSL-----LSNSS-------------
Pats1_Ddis VMSELEHPNIVQLKGLCLDPL-CIVTEYLPHGNLYSF-----LHKPE-------------
QkgA_Ddis IMSNLNHPNIVKLYGLMHNPP-RMVMEYVEHGDLYHL-----CQDKE-RY----------
QkgA_C2d_Ddis IMSNLNHPNIVKLYGLMHNPP-RMVMEYVEHGDLYHL-----CQDKE-RY----------
Roco10_Ddis SLYNFRHSNVLSIIGISMNPI-AIITENPTFGSKGSTTLSEYIQDR-QKH----------
Roco11_Ddis IMSSLNHLNIVKLFGSMQNPP-RMVMEFAPHGDLYHF-----LEKKK-------------
Roco4_Ddis IMSNLNHPNIVKLYGLMHNPP-RMVMEFVPCGDLYHR-----LLDKA-------------
Roco5_Ddis LSNTLTHPSIVSLKGYCLDPC-CIVMEYIPNGTLYSH-----LRKSF-------------
Roco6_Ddis VMSDLKHSNVVNLLGFTLSPF-TMVMEYIDCGDLHKF-----LHSPIGDQ----------
Roco7_Ddis ITGELRHANTVSLMGVSLSPF-CLVTELLQYGDLAKF-----IRNT---A----------
Roco8_Ddis LMSGLSHSNIVLMKGFCFEPY-AIVMEYMDIGSLSSF-----LKKKKEDG----------
Roco9_Ddis CLSSFIHDNILDLKGFCLEPL-AIITEFQSGGNLYDY-----IHDLK-------------
LRRKd_Spur IMAKLDHPYIVNLVGVSIRHL-CFAMDYAPLGDLRSY-----LFAEHQSARP---HFVKR
LRRKc_Spur IMVKLDHPCIVNLVGVSIRHL-CFAMDYAPLGDLQSY-----LFAEHQSARP---HFVKR
LRRKb_Spur VLRHLQHPSLVSMEGVGLNPR-ILVMELAPLGSLNTL-----LASGR-------------
LRRKa_Spur IINNLDHPHIVPLLGFCRHPM-CLILELAPQGALDTR-----MENFKRVG----------
AqueK485_Aque LLKNLSTPHIISSLGFHYSVP-VLALELSPLGSVRKY-----LNDGNK------------
AqueK486_Aque VLQESHHPFLVCLVGVSVHPLMALILEEAPMGSFERH-----LIKKS-------------
AqueK487_Aque MMHQLQHKNILSLVGLAFQPL-RLILELAPLGDLKNS-----LKPFRQEK----------
AqueK488_Aque KLCMMEHDFVVEFVGLLTNPW-SFILEWAPLMSLEKI-----RKSYEEQFKT--------
AqueK489_Aque ---------------------------------MEDV-----ILEHTI------------
AqueK490_Aque MLSLLSHPNIIKAYGYCFSPP-SLVIERSPLGTLLQK-----LSDNEQ------------
AqueK491_Aque LLKDLDHEYIINFIGLTLQPL-CFMLEWASKGSLHGI-----LQSYYRTD----------
AqueK492_Aque LLQKSYHPSIVCLVGVNVHPLTALILEEAPMGSLDRH-----LIKES-------------
AqueK493_Aque LLQKSHHPFIVCLVGVNVHPLTALILEEAPMGSLERH-----LIKES-------------
AqueK494_Aque ILSQMDHPNIIGLVGVCLRPKPMLLIEYAELGSLSSF-----SP-Y--------------
AqueK495_Aque VLTNISHQYLISTAGFLTAPL-SIVFPLAPLGSLQDH-----LDLCP-------------
AqueK496_Aque FLSTLKHQNITKLIGVRTKPVYCLLLELAPMKSLRSM-----LKDYQLCK----------
AqueK497_Aque VLAQLSHPNIVSILGVSLRPM-CIALELAPMGSLFGI-----LDKKLEAIKTAQADLPTA
AqueK498_Aque ILSPLRHPYIIQLFGVSARPL-GLVLELAPKGSLKSL-----LKEYSEAQ----------
LRRK2_Hsap ----------ASLTRTLQHRIALHVADGLRYLHSA--MIIYRDLKPHNVLLFTLYP----
LRRK1_Hsap -----F----IPLGHMLTQKIAYQIASGLAYLHKK--NIIFCDLKSDNILVWSLD-----
CG5483_Dmel ----------AHMGPHTFQTLVLQAARAIEYLHRR--RIIYRDLKSENVLVWELPQPHT-
LRRK2_Mmus ----------ASLTRTLQHRIALHVADGLRYLHSA--MIIYRDLKPHNVLLFTLYP----
LRRK1_Mmus -----F----MPLGHMLTQKIAYQIASGLAYLHKK--NIIFCDLKSDNILVWSLS-----
T27C10.5_Cele ----------TKLSLGVIKESAVQVARALEYLHSA--HIIYRDLKSENVLGWRFPAPF--
GbpC_Ddis ----------IEISWGLRLQIASEIAKGMQHLHSHNPPVIHRDLKSPNILLNGIT-----
Pats1_Ddis ----------MEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSPNILLASIN-----
QkgA_Ddis ----------ASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNIFLKSLD-----
QkgA_C2d_Ddis ----------ASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNIFLKSLD-----
Roco10_Ddis ----------PEIPWNIKLKIALDIARAMDKLNSHSPPFLLTNLTSSGIILEKSNDHQSS
Roco11_Ddis -----------NIKWSFKVRLMLDIAKGIEYLQNQNPPIVHRDLRSPNIFLFSLD-----
Roco4_Ddis ----------HPIKWSVKLRLMLDIALGIEYMQNQNPPIVHRDLRSPNIFLQSLD-----
Roco5_Ddis ----------SSITWQLKLKIAINIADAIKHMHGFTPKICHRDLKSPNILMLS-D-----
Roco6_Ddis ----------LNGNWALILKLALDIAKGMEFLHSVTPPLLHRDLKSPNVLLSMKD-----
Roco7_Ddis ----------ETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILLGGSS-----
Roco8_Ddis ----------QVLDWQMLLKIVTDIASGMAFLHNITPPLVHRDLKSPNILLASHP-----
Roco9_Ddis ----------NPLDWQLRIKIAKGIAASLQTLHDSRPSVVHRDLKSPNILLSSKD-----
LRRKd_Spur NI-VLE----PVLSRMLTYKISLQVASAVGYLHRK--DIIYCDLKTDNILLFSSD-----
LRRKc_Spur NI-VLE----PVLSRMLTYKISLQVASAVGFLHSK--DIIYCDLKTDNILLFSSD-----
LRRKb_Spur -----------IKNRNLQHRIAMQVAEGLAFLHKN--RIVYRDLKPDNVLIFSLAL----
LRRKa_Spur ----------ARLTPHTLQELVVQVSSAVAYLHSK--DIIYRDLKAENVLVWKFPQPYS-
AqueK485_Aque ------------LLQSGVHQIALQVLSAIKY-----------------------------
AqueK486_Aque ----------TPIPRLTMFRIAAQVAAALRFLHQH--GIIFRDLKAANVLLWSLD-----
AqueK487_Aque ----------IKLNCRTLKQLIYQVADAME------------------------------
AqueK488_Aque -----HKPEYYYLCPVSLYLILLQVCDGLHYLHAPPIGIIHSDLKLSNI-----------
AqueK489_Aque -----------SVSPFLRMRIVYQLASALKTLHSL--KIIHRNVCLENIIVYSLS-----
AqueK490_Aque -----------KISRLVRFHISCQVASALAYLHKH--NVIYRTLKSDSVLTWSLE-----
AqueK491_Aque ----------SKVSPWTLVEAGRQVANGLSYLHSR--NVVYYDLKSPNILVFEFPSADES
AqueK492_Aque ----------TPIPRLTMFRIAAQVAAALRFLHQH--GIIFRSLKAANVLLWSLD-----
AqueK493_Aque ----------TLIPRLTMFRIAAQAAAALRFLHQH--GIIFRSLKAANVLLWSLD-----
AqueK494_Aque ----------STVSPSLKHRIAMQVASALAFLHKN--NIIYRDLKPSNILIFSLSL----
AqueK495_Aque ----------SGIGDKISHVLLHQVAQGLQYLHSL--HIIHRDIKPGNILVWSLT-----
AqueK496_Aque ----------LTMEPITLKQCAKQISDGLNYLHTH--QIVHLDMKSPNVLVWEFPIAGMP
AqueK497_Aque NIKMPG----GVLGHQISARIALQVALATRYLHKI--GIVYRDLKSDNVLIWSLDV----
AqueK498_Aque ----------THIQSSAMQAVTLQISDALKYLHDL--RIIYRDLKSDNVLVWQFPSPYDV
.
LRRK2_Hsap ---------------N-AAIIAKIADYGIAQYCCRM-GI---KT-----SEGTPGFRAPE
LRRK1_Hsap --------------VK-EHINIKLSDYGISRQSFHE-GA---LG-----VEGTPGYQAPE
CG5483_Dmel ----E------D-SPR-NLVHIKIADYGISRQTAPS-GA---KG-----FGGTEGFMAPE
LRRK2_Mmus ---------------N-AAIIAKIADYGIAQYCCRM-GI---KT-----SEGTPGFRAPE
LRRK1_Mmus --------------AK-EHINIKLSDYGISRQSFHE-GA---LG-----VEGTPGYQAPE
T27C10.5_Cele -------------SPQ-TDVLLKLGDYGISRSVLPSGGA---KG-----FGGTEGFMAPE
GbpC_Ddis --------------EG-QNSVATIIDFGTSTALYGG-AA---LI----RCVDQPLWLGPE
Pats1_Ddis --------------EN-AQTIAKVVDFGLSGLQHTI--T---N-----RGVENPLWLAPE
QkgA_Ddis --------------EN-SPVCAKIADFGLSQQSV-Y-SV---SG-----LLGNFQWMAPE
QkgA_C2d_Ddis --------------EN-SPVCAKIADFGLSQQSV-Y-SV---SG-----LLGNFQWMAPE
Roco10_Ddis -GNGL--------EIE-PFVNAKIIDFSQSSFLPSL--F---PT-----STTPKSYHSPE
Roco11_Ddis --------------EN-APVCAKVADFGLSQQSL-Y-SV---SG-----LLGNFQWMAPE
Roco4_Ddis --------------EN-APVCAKVADFGLSQQSV-H-SV---SG-----LLGNFQWMAPE
Roco5_Ddis --------------MN-AAVVCKVSDFGETRAVVTS-AL---GR----DKLSNPIWLSPE
Roco6_Ddis -----------------GVYTAKVGDFGLSSRMFIQ-AL---KHKLRNFPVGNITWVAPE
Roco7_Ddis --------------M--DNLVAKVGDFGLSIKPIGK-EV---KG----RKVWNWRWLAPE
Roco8_Ddis --------------TNPNEISAKVSDFGLSRSIVQN-FS---SK-----VVDNPTWQSPE
Roco9_Ddis --------------S--LTMECHLCDFSLSGFSTTV--A---N-----RSVQNPVWLAPE
LRRKd_Spur --------------VN-EDVNIKLIDYGISKKYDLM-GA---MG-----MAGTPGFCAPE
LRRKc_Spur --------------VN-EDVNIKLTDYGISRKYDLM-GA---MG-----MAGPPGFCAPE
LRRKb_Spur ---------------G-TLQNAKISDYGISRFATPY-GL---KS-----SEGTPGYRAPE
LRRKa_Spur ----P--------NPA-DPIKVKLADYGISVTALPS-GT---KG-----YGGTPGYMAPE
AqueK485_Aque ------------------------------------------------------------
AqueK486_Aque --------------ET-SLCH---------------------------------------
AqueK487_Aque ------------------------------------------------------------
AqueK488_Aque ------------------------------------------------------------
AqueK489_Aque --------------LD-EQVNIKLGGFSRSCLEMSQ-GL----A-----VGEHGRFPAPE
AqueK490_Aque --------------FE-DEVSVKLAHFDRAAFSTPT-GI---LS-----KTDFSFYPAPE
AqueK491_Aque LRVSLESSPVLDKLG-KFPVHVKITDLGISRKITPG-GV---VG-----YKGTPAFMAPE
AqueK492_Aque --------------ET-SLCHSKLTDFGIATHLAPL-GV---MG-----IQGDKCVIAPE
AqueK493_Aque --------------ET-SLCHSKLTDFGIATHLAPL-GV---MG-----IQGDKSVIAPE
AqueK494_Aque ---------------N-SPVNAKLSDYGISTFATTT-GL---NQ-----DIGTAGYKAPE
AqueK495_Aque --------------LS-DGILVKITDYGSSYYIDTF-GC---KG-----SRGTEDYMAPE
AqueK496_Aque RKERL--------KYA-GNVWLKIADYGISQVATSM-MMKVTTN-----QPGTPGYMAPE
AqueK497_Aque ---------------N-ESVNAKLADYGISRFANPG-GI---KG-----EEGTPGYMAPE
AqueK498_Aque LVPAL------P-VHT-DVVKVKLSDYGISQFASTQ-GA---KG-----LVGTPGFMAPE
LRRK2_Hsap VAR--G-NVIYNQQADVYSFGLLLYDILTTGGRIVEGLK------------------FPN
LRRK1_Hsap IRP----RIVYDEKVDMFSYGMVLYELLSGQ-RPALGHH---Q----------------L
CG5483_Dmel IIRYNG-EEEYTEKVDCFSFGMFIYENISLR-QPFEGHE---------------------
LRRK2_Mmus VAR--G-NVIYNQQADVYSFGLLLHDIWTTGSRIMEGLR------------------FPN
LRRK1_Mmus IRP----RIVYDEKVDMFSYGMVLYELLSGQ-RPALGHH---Q----------------L
T27C10.5_Cele IVRFNG-EEEYTQKVDCFSFGMFLYELLTLK-FPFESEE---------------------
GbpC_Ddis VLAG----TAYSEPSDVYSFGIILWELYTRA-HPFDEFQ-FGQ--------------WMS
Pats1_Ddis ILNK---TKEASTQTDVYAFGVILWELVTRK-DYFGEIG-F-----------------MT
QkgA_Ddis TIGV--EDESYTEKVDTYSFAMILFTILTGE-IPFDEYS-FGKM---------------Q
QkgA_C2d_Ddis TIGV--EDESYTEKVDTYSFAMILFTILTGE-IPFDEYS-FGKM---------------Q
Roco10_Ddis VLQ----KLNYHENSDVYSFGIILYELLTRS-IAFQDHD-----R---------------
Roco11_Ddis TIG---AEESYTEKIDTYSFSMILFTILTGE-CPFDEFTSFGKM---------------E
Roco4_Ddis TIGA--EEESYTEKADTYSFAMILYTILTGE-GPFDEYS-YGKI---------------K
Roco5_Ddis IMRG----DEYTEKADVYSFGIVLWEILTGL-LPFDEYP-VAHSS------------FMY
Roco6_Ddis ILR----EEEYTVKSDVYAFGLILHELLTRK-HPYREFN-YSMV---------------S
Roco7_Ddis CMG----DGQYTEKIDIYSYAIVLWEIITRD-LPFEEYVD--QLK------------WNS
Roco8_Ddis VLK----GMEYNEKSDIYSFGMILWECYHLE-LPFDEFD-F-K--------------FMS
Roco9_Ddis VINN----ELCSDKSDVYAYGVILFELLSRT-RFFSNIT-F-----------------MS
LRRKd_Spur ILQ----GKTFDEKVDWFSYGMFLYHLMTGL-VPYYDQH-S-R----------------I
LRRKc_Spur ILQ----GKVFDEKVDWFSYGMFLYHLMTGL-VPYYDQH-S-R----------------I
LRRKb_Spur VIR--G-TSNYNTEVDIYSFGILLYELVSEGHRPFEEME------------------FRT
LRRKa_Spur IVQYDG-KETYNEKVDCFSFGMFMFELMSLQ-RPFECLVGKDVGR------------LSE
AqueK485_Aque ------------------------------------------------------------
AqueK486_Aque ------------------------------------------------------------
AqueK487_Aque ------------------------------------------------------------
AqueK488_Aque ------------------------------------------------------------
AqueK489_Aque MSNY---LYEYDQRADVFSFAFTSYEILTRK-KL-KCRK---G----------------V
AqueK490_Aque MVRY-EFSEEYTEKVDIYSFGILLYELVARW-QPFTSDK-T-A-----------------
AqueK491_Aque ILRYV-GKEACTEKVDVFSFGMFMYELLAQQ-FPFERQ----------------------
AqueK492_Aque VLYIGQKRTIYNHKADIFSFGMLLYQMIARR-HPFHNVQ-P------------------V
AqueK493_Aque VLYIGQKRTIYNHKADIFSFGMLLYQMIARR-HPFHNVQ-P------------------V
AqueK494_Aque ILKAKTSKMPYNTMVDIYSFGIVLFQLVTDGHTPFEELMP-------------------H
AqueK495_Aque LYLSA-RKRNYDEKVDIFSFGILLFNVVTGK-KFAPNFN-RSRHEAGGRREAFLSIPHLS
AqueK496_Aque LFET--GQEIYSTKVDVFAYGMTLYEIISLQ-APFQKQE-AMKR----------------
AqueK497_Aque AIKRRGEDQAFDEKVDIFSFGMLLFELITGQ-RPFESMS------------------TGQ
AqueK498_Aque ILMYYG-KEAYNEKVDIFSFAMLIYEMITFR-LPFEHLT-------------------PS
LRRK2_Hsap ------------------EFDELEIQGKLPDPVKEYG-----CAPWPMVEKLIKQCLKEN
LRRK1_Hsap ------------------QIAKKLSKGIRPV-LGQP-----EEVQFRRLQALMMECWDTK
CG5483_Dmel ------------------SIKECILEGSRPA-LTQRE-----TQFPTCCLDLMVLCWHEQ
LRRK2_Mmus ------------------EFDELAIQGKLPDPVKEYG-----CAPWPMVEKLITKCLKEN
LRRK1_Mmus ------------------QIVKKLSKGIRPV-LGQP-----EEVQFHRLQALMMECWDTK
T27C10.5_Cele ------------------HVKERMLDGARPV-LLPHE-----LLLPTPMLDLLVHCWSAH
GbpC_Ddis ------------------KLEDEIIRGLRPT-IPPTC--------PPEYVELIQSCWTHE
Pats1_Ddis ------------------LIEEKVINGERPK-IPEDC--------PEMYSKLIVECWQTD
QkgA_Ddis ------------------FINLIREENLRPT-LPFD-------C-DPRLSNLIQLCWSTN
QkgA_C2d_Ddis ------------------FINLIREENLRPT-LPFD-------C-DPRLSNLIQLCWSTN
Roco10_Ddis -------------------FSNIVISGQRPS-IPLD-------C-LPSFADLIKDCWSGE
Roco11_Ddis ------------------FIRKIREEDLRPT-IPSD-------C-PPTISNLIELCWSGD
Roco4_Ddis ------------------FINMIREEGLRPT-IPED-------C-PPRLRNVIELCWSGD
Roco5_Ddis ------------------QLEDEITNGLRPT-IPQNSV-----CGHPDFITLITDCWQND
Roco6_Ddis ------------------LQEDAIKNGLRPT-ISPSYT---QTVTGHEYCGLIQDCWDSD
Roco7_Ddis ------------------IIEDKIMKGLRPT-IPNE-------C-PPDMKQLITDCWSGD
Roco8_Ddis ------------------TLEDNILSGLRPS-INQ--------NCNRMYSSLITKCWNAD
Roco9_Ddis ------------------EVEGLITEGVRPS-LPSHN--------LPEYDSLLNICWAQD
LRRKd_Spur ------------------EIELAVNEGRKPT-FNFHEYTMPPKQVFPALGALMESCWQNK
LRRKc_Spur ------------------EIQLAVNEGRKPT-FNFHEYKMPPRQVFPALGALMESCWQDK
LRRKb_Spur ------------------EIDEAVIKGQHLPPISQGG-----VAPWPDLQELIDHCTEHV
LRRKa_Spur ------------------VIKQLIKDGQRPV-LSRKE-----KSYPTYMLDLLSWCWAQD
AqueK485_Aque ------------------------------------------------------------
AqueK486_Aque ------------------------------------------------------------
AqueK487_Aque ------------------------------------------------------------
AqueK488_Aque ------------------------------------------------------------
AqueK489_Aque ------------------RFQTATGNADRPN-LKPL-----N-GLCPYFTPLLDKCWNND
AqueK490_Aque -------------------------MAHKPK-LTGL-----STYGFGSLVKLMEECWEED
AqueK491_Aque ------------------------------------------------------------
AqueK492_Aque ------------------RIDTKVVQGDRPS-TVDMPI---AETGYFFLTRLMEKCWKDK
AqueK493_Aque ------------------RIDTKVVQGDRPS-TVDMPI---AETGYFFLTRLMEKCWKDK
AqueK494_Aque ------------------EKDKAVEEGRLIKD-PSYY----GGAPWPDMHDIIRHCLQYV
AqueK495_Aque IIASAIEEQRLVGSSNQSPATLLLKDGVHPA-AREGHI---STCISTCMQVILEDCLSID
AqueK496_Aque --------------------NAEVRAGKRPP-TGN--K---EKHTPLLLQDLMRLCWSKD
AqueK497_Aque ------------------EVNRAVIQRERPQ-VSEGN----MEPSFPGMIELMEDCWRHL
AqueK498_Aque ------------------QANQANENGARPT-LKRID-----LPCPVLIRELMVWCWQQS
LRRK2_Hsap PQERPTSAQVF------------------------------------DI
LRRK1_Hsap PEKRPLALSVVSQMK------------------------------DPTF
CG5483_Dmel PRRRPTASQIV------------------------------------SI
LRRK2_Mmus PQERPTSAQVF------------------------------------DI
LRRK1_Mmus PEKRPLALSVVSQMK------------------------------DPTF
T27C10.5_Cele PESRPSSSQLV------------------------------------GF
GbpC_Ddis PNSRPTFTSIVEIL--------------------------------GQI
Pats1_Ddis ASQRPKFSEIED-----------------------------------RL
QkgA_Ddis PKKRPSFTFIIKEL---------------------------------LE
QkgA_C2d_Ddis PKKRPSFTFIIKEL---------------------------------LE
Roco10_Ddis PLNRPSPSKII-------------------------------------S
Roco11_Ddis PKKRPHFSY---------------------------------------I
Roco4_Ddis PKKRPHFSYIV-------------------------------------K
Roco5_Ddis PLKRPTFID---------------------------------------I
Roco6_Ddis IDRRPTFNKIVKRIK-------------------------------QII
Roco7_Ddis PKKRPSFNSILERL--------------------------------STM
Roco8_Ddis PNLRPSFNSILK-----------------------------------TL
Roco9_Ddis PTCRPSFIEITKKLEEIELIL--KTHTPVEPVYTE-----TSKNQHIQL
LRRKd_Spur PGERPHGETTLQLLS------------------------------EPSF
LRRKc_Spur PGKRPHGKTILQLLS------------------------------EPSF
LRRKb_Spur PESRPTAQEAFEK---------------------------------LSS
LRRKa_Spur SRDRPSMEQIK------------------------------------DV
AqueK485_Aque ------------------------------------------------L
AqueK486_Aque -----------------------------------------------SK
AqueK487_Aque ------------------------------------------------Y
AqueK488_Aque ------------------------------------------------L
AqueK489_Aque PHKRPYFIEILH-----------------------------------QF
AqueK490_Aque PTLRPSALDLLH-----------------------------------LL
AqueK491_Aque ------------------------------------------------N
AqueK492_Aque ADDRPETSELISD---------------------------------VSK
AqueK493_Aque ADDRPETSELISD---------------------------------VSK
AqueK494_Aque PNNRPRAQDIFDRMCMPDF----------------------MALRHVVP
AqueK495_Aque PIKRPTAEGVASR---------------------------------LVI
AqueK496_Aque PSARPKMKECLQ-----------------------------------WT
AqueK497_Aque AADRPTADEVVQR---------------------------------ISA
AqueK498_Aque EELRPTASQITKVSQMDQF-LRLADAIRVNNFGSQVAGSCYRILKSPVF