Alignment of Family LRRK

Protein (view, download) , Domain (view, download) 
LRRK2_Hsap      MASGSCQGCEE-D-----------------------------------------------
LRRK1_Hsap      MAGMSQRPPSM-----Y--WCV--G-----------------------------------
CG5483_Dmel     MEHPKTGTETA-L---E--ACD-------------------YFVDE--------------
LRRK2_Mmus      MASGACQGCEE-E---E--E----------------------------------------
LRRK1_Mmus      MAGTSQRPPSM-----Y--WCV--G-----------------------------------
T27C10.5_Cele   MDLSSGGPSSS-S---D--VAS--------------------ELDN--------------
GbpC_Ddis       MSQKQKPIRFQ-----D--YQF--T-----------------------------------
Pats1_Ddis      MEILNLSIEFHIPDGNT--L----K---------------------------KMV-RVDN
QkgA_Ddis       MDLEQDEWMSQ-----R--Q----R-----------------------------------
QkgA_C2d_Ddis   MDLEQDEWMSQ-----R--Q----R-----------------------------------
Roco10_Ddis     MSGLLDDDEII-----Q--VS---------------------------------------
Roco11_Ddis     METSQIRNGF--------------------------------------------------
Roco4_Ddis      MDSSQQLQESQ-----Q--L----Q-----------------------------------
Roco5_Ddis      MEVIKKEKKDK-----E--KK---------------------------------------
Roco6_Ddis      MNSIHKQHYTI-----N--SNH--Y-----------------------------------
Roco7_Ddis      MDGYSSLSSSG-----N--SIA--PPRPTNNSVGGGSNSNNYNQREITTPLRGMVPNLGD
Roco8_Ddis      MFDYNQLNKLK-----D--KIQ--S-----------------------------------
Roco9_Ddis      MTSIANLFDKK-----S--KRS--N-----------------------------------
LRRKd_Spur      VPQPY-------------------------------------------------------
LRRKc_Spur      MDNYDMLQDAC-----T--ALL--------------------------------------
LRRKb_Spur      MESPVTPDEER-I---R--RKL--L-----------------------------------
LRRKa_Spur      MVNMVVL-----------------------------------------------------
AqueK485_Aque   MDGTEVIVAVF-G-------CP-------------------GVGKS--------------
AqueK486_Aque   MMTAKAPDYQP-V---E--RYG--H-----------------------------------
AqueK487_Aque   MATWCSLQPV--------------------------------------------------
AqueK488_Aque   MQNMGVVKEHV-F---D--CKM--E-----------------------------------
AqueK489_Aque   MAKAAESENTS-------------------------------------------------
AqueK490_Aque   MAALLPPETQG-I---D--KAI--F-----------------------------------
AqueK491_Aque   MSGKENVYAPS-----D--VT---------------------------------------
AqueK492_Aque   MAGVMQDDAKL-L---H--KFC--H-----------------------------------
AqueK493_Aque   MGQ---------------------------------------------------------
AqueK494_Aque   MSAGAGRRRHS-M---E--ASA--F-----------------------------------
AqueK495_Aque   MLTPIIPYFLI-YG--GFSCLVVSI-----------------------------------
AqueK496_Aque   MAEVRKLAETL-----G--TIL--S-----------------------------------
AqueK497_Aque   MLSSVKFLGAG-I---D--K----------------------------------------
AqueK498_Aque   MARGSSFLRFF-----E--PSV--D-----------------------------------
                :

LRRK2_Hsap      ---EET-----------LK-KL-------------IVRLNNVQEGKQIETLVQI------
LRRK1_Hsap      ---PEE-----------SAVC--------------------------PERAMET------
CG5483_Dmel     ---VIE-----------AS-S--------------------------IRDA---------
LRRK2_Mmus      ---EEA-----------LK-KL-------------IVRLNNVQEGKQIETLLQL------
LRRK1_Mmus      ---TEG-----------LAVC--------------------------PGPAMET------
T27C10.5_Cele   ---SDA-----------MQ-L--------------------------VRQA-------VL
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ---TTK-----------I---------------------------------GEM------
QkgA_Ddis       ---QQQ-----------M----------------------------------EF------
QkgA_C2d_Ddis   ---QQQ-----------M----------------------------------EF------
Roco10_Ddis     ---PDS-----------I----------------------------------IT------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      -----------------Q----------------------------------QY------
Roco5_Ddis      ----DK-----------E----------------------------------EK------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      GSSSQT-----------L----------------------------------LF-KNILL
Roco8_Ddis      ---SDG-----------L----------------------------------QIKDRTYL
Roco9_Ddis      ---EDT-----------G-----------------------------------EKEETKK
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------------------------------------------EI------
LRRKb_Spur      ---DT-LLLL--------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ---TFI-----------SN-A--------------------------LEGQ---------
AqueK486_Aque   ----ST-----------V--RVGDYLYMWGGDQPDLPRVHNNEKKKSM---CSV------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ---NE---------------D--------------------------IRTLV-T------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ---A------------------------------------------------E-------
AqueK491_Aque   ---EDL-----------T----------------------------------A-------
AqueK492_Aque   ---DGK-----------IE-KIKDFV--ATVE----------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ---SR-PALFRPHFSSTS--N--------------------------LNASV-A------
AqueK495_Aque   ---HYPI--------SSKD-V--------------------------LKSLKS-------
AqueK496_Aque   ---AEP-----------SD-N--------------------------QKKLFE-------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ---PSL-----------VD-D--------------------------TDRLIDF------


LRRK2_Hsap      ------LEDLLVFTYSERASKLFQGKNIHVPLLIVLDSYMRVASVQQVGW----------
LRRK1_Hsap      ------L--------------------------NG--------------A----------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------LEDMLVFTYSDRASKLFEDKNFHVPLLIVLDSYMRVASVQQAGW----------
LRRK1_Mmus      ------H--------------------------NG--------------A----------
T27C10.5_Cele   FEN---------------------------------------------------------
GbpC_Ddis       ----------------------------------------A------TKD----------
Pats1_Ddis      ------S---------------------------------R------LLL----------
QkgA_Ddis       ------S---------------------------------R------IGI----------
QkgA_C2d_Ddis   ------S---------------------------------R------IGI----------
Roco10_Ddis     ------S--------------------------SIGSA--S------LNY--SVNGADDN
Roco11_Ddis     ------N---------------------------------K------VEV----------
Roco4_Ddis      ------T---------------------------------R------VGI----------
Roco5_Ddis      ------K--------------------------DKEKK----------DKSEKKEKKDKE
Roco6_Ddis      -------------------------------------------------N----------
Roco7_Ddis      LQDVEFF---------------------------------C------SIL----------
Roco8_Ddis      YKTYRSV---------------------------------F------VGY----------
Roco9_Ddis      ---SRS------------------------------------------GT----------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------L--------------------------EK-------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------ME-VCHLRTGRWEQKPTT---GDPPL----------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------F--------------------------NRGK-----------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   --L---Y---------------------------------R-------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------S--------------------------SRGMQPLK------EQD----------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------L--------------------------SA-------------------------


LRRK2_Hsap      ---------------------------SLLCKLIEVCPGTMQSLMGPQ------------
LRRK1_Hsap      ---------------------------G--------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ---------------------------SLLCKLIEVCPGTLQSLIGPQ------------
LRRK1_Mmus      ---------------------------E--------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ---------------------------E--------------------------------
Pats1_Ddis      ---------------------------D--------------------------------
QkgA_Ddis       ---------------------------E--------------------------------
QkgA_C2d_Ddis   ---------------------------E--------------------------------
Roco10_Ddis     KSI---PPS------SPQQNLLE---ND--------------------------------
Roco11_Ddis     ---------------------------D--------------------------------
Roco4_Ddis      ---------------------------D--------------------------------
Roco5_Ddis      KKEKEKKEKKEKEKEKEKDKEKDGGLFS--------------------------------
Roco6_Ddis      ---------------------------E--------------------------------
Roco7_Ddis      ---------------------------D--------------------------------
Roco8_Ddis      ---------------------------ECVDW----------------------------
Roco9_Ddis      ---------------------------LKFKT----------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ----------------------------------------GVRSYAAAAIGREIFYFGGY
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ---------------------------D--------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ---------------------------E--------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      --------------DVGNDWEV--------------------------------------
LRRK1_Hsap      --------------DTGGKPSTRGGDPAARSRR---------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      --------------DIGNDWEV--------------------------------------
LRRK1_Mmus      --------------DMGSKLSLPGGSSTVQCPS---------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       --------------A---------------------------------------------
Pats1_Ddis      --------------K---------------------------------------------
QkgA_Ddis       --------------V---------------------------------------------
QkgA_C2d_Ddis   --------------V---------------------------------------------
Roco10_Ddis     --------------T---------------------------------------------
Roco11_Ddis     --------------V---------------------------------------------
Roco4_Ddis      --------------V---------------------------------------------
Roco5_Ddis      --------------I---------------------------------------------
Roco6_Ddis      --------------S---------------------------------------------
Roco7_Ddis      --------------N---------------------------------------------
Roco8_Ddis      --------------I---------------------------------------------
Roco9_Ddis      --------------L---------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      --------------------------------S---------------------------
LRRKb_Spur      --------------------KLCS-------QYVKSSPNSTIVLMILMCSPFIMDFATLS
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   CNHEDCYYNSLYSFNV----DT--------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   --------------VI--------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   --------------VLASPAEFI--------NAMKTSKAEE--MLVYACGKL-------A
AqueK495_Aque   -------------------------------SI---------------------------
AqueK496_Aque   -------------------------------DH---------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      TEIPPGAVAS---TLQEYHAHAQVLQVMDQHTYNADIQEAGCNALAA-------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   QAL-DDD-NPELADVKEEEVIRVTYQMMINHPLNSNLLQLACEVFLRCNSKAAYRGIVEE
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      -------------------------------------------LGVHQLILKMLTVHNAS
LRRK1_Hsap      -----------------------------TEGIRAAYR--RGDR----------------
CG5483_Dmel     -----------------------------REE----------------------------
LRRK2_Mmus      -------------------------------------------LGIHRLILKMLTVHHAN
LRRK1_Mmus      -----------------------------MEEIHTAYK--QRNL----------------
T27C10.5_Cele   -----------------------------VEL----------------------------
GbpC_Ddis       -------------------------------------------Y----------------
Pats1_Ddis      -------------------------------------------F----------------
QkgA_Ddis       -------------------------------------------I----------------
QkgA_C2d_Ddis   -------------------------------------------I----------------
Roco10_Ddis     -------------------------------------------L----------------
Roco11_Ddis     -------------------------------------------V----------------
Roco4_Ddis      -------------------------------------------I----------------
Roco5_Ddis      -------------------------------------------V----------------
Roco6_Ddis      -------------------------------------------I----------------
Roco7_Ddis      ---------------FC--------------------RS--SST----------------
Roco8_Ddis      -------------------------------------------F----------------
Roco9_Ddis      -------------------------------------------F----------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -----------------------------SDSVKEAYKYMQALP----------------
LRRKb_Spur      -------------------------MMQVSD-----------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   -----------------------------FER----------------------------
AqueK486_Aque   -------------------------------------------FKWKKLSPIYTTSHHGP
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ---------------WC--------------------KE--GNT----------------
AqueK491_Aque   ---------------AA--------------------MW--GDV----------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   YAVFRTQSDWSIATLYCKELSQSQAYLDIAG-----------------------------
AqueK495_Aque   --------------------------------LPLL--HP--------------------
AqueK496_Aque   ----------------------------------ME--YGR-KT----------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----------------------------SERLPRLLS--R-------------------


LRRK2_Hsap      VNLSVIGLKT-----LDLLLTSGK------------------------------------
LRRK1_Hsap      ------G-----------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      VNLSIVGLKA-----LDLLLDSGK------------------------------------
LRRK1_Mmus      ------S-----------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------G-----------------------------------------------------
Pats1_Ddis      ------G-----------------------------------------------------
QkgA_Ddis       ------G-----------------------------------------------------
QkgA_C2d_Ddis   ------G-----------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------G-----------------------------------------------------
Roco4_Ddis      ------G-----------------------------------------------------
Roco5_Ddis      ------G-----------------------------------------------------
Roco6_Ddis      ------N-----------------------------------------------------
Roco7_Ddis      ------Q-----------------------------------------------------
Roco8_Ddis      ------G-----------------------------------------------------
Roco9_Ddis      ------G-----------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------E-----------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   MMKAYCGMVAIKVNGEDYLVVIGGLGPMASSNNTPPQPGAQYSGGGFITYQRCNEIHFYK
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------G-----------------------------------------------------
AqueK491_Aque   ------A-----------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------S-----------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ---------------------RSD------------------------------------
Pats1_Ddis      ---------------------RSDFD--------------------PSQF----------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ---------------------------SPPPPLPTQTINTSSSPPPPTI-----------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      -----------------GWVGN-LTEPTPP------------PPPPPSSVSAQSTAEANA
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   LSTGQWISPTVTGDRPPP------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ----------------------------------------------------G-------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ----------------------------------------------------R-------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -----------------------------------QLIV-------------PQKTATIS
QkgA_Ddis       ----------------------------------------------------S-------
QkgA_C2d_Ddis   ----------------------------------------------------S-------
Roco10_Ddis     --ITTTTTTTTTTAMSPVATTTTSSPTISASPTYITSPSGTRLSGGNTFNAQQ-------
Roco11_Ddis     ----------------------------------------------------P-------
Roco4_Ddis      ----------------------------------------------------P-------
Roco5_Ddis      ILLNPTTQENHKK-----------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ----------------------------------------------------K-------
Roco8_Ddis      ----------------------------------------------------NC------
Roco9_Ddis      ----------------------------------------------------TS------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------------------------------------------D-------
LRRKb_Spur      ----------------------------------------------------K-------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ----------------------------------------------------L-------
AqueK490_Aque   ----------------------------------------------------R-------
AqueK491_Aque   ----------------------------------------------------L-------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------------------------------------------V-------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ----------------------------------------------------A-------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------ITLLILDEESDI------------------------------------------
LRRK1_Hsap      ---ARD-----------LLE-----------------EAC------------DQCASQLE
CG5483_Dmel     ---VRQ-----------I-----------------------------------------K
LRRK2_Mmus      ------LTLLILDEECDI------------------------------------------
LRRK1_Mmus      ---ARD-----------LLR-----------------GVC------------EESESSQE
T27C10.5_Cele   ---LAD-----------LFK---------VN--------------PWVW------NRVDR
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      FHVLSD-----------LN-----------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ---VRD-----------KLFPFY-----SHHSLGIERAMCGNQTLKEMPGRSDQE-ELYA
LRRKb_Spur      ---LKD-----------LVH-KKNIHSQV-------------------------LEIMDK
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ---KR------------------------------------------------------E
AqueK486_Aque   ---IYDFTLTSINNSSAI------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   -----D-----------LAQ-YW-----V-------------------------EENKDK
AqueK489_Aque   ---LEK-----------LL-----------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ---LES-----------LL-----------------------------------------
AqueK492_Aque   ----PEILFNLLNNRR--------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ---LRN------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ---LQK-----------II----------------------NHP------------IQRY
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ---------------------------------------------------------KDD


LRRK2_Hsap      ----------------------------------FMLIFDAMHSFPANDEVQKLGCKALH
LRRK1_Hsap      KG----------------------------------------------------------
CG5483_Dmel     HG----------------------------------------------------------
LRRK2_Mmus      ----------------------------------FLLIFDAMHRYSANDEVQKLGCKALH
LRRK1_Mmus      KG----------------------------------------------------------
T27C10.5_Cele   HG----------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -------------------KSLSSYNI--KNNDELIFKKRQKKTNPGN------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      RF----------------------------------------------------------
LRRKb_Spur      HKDDPKVQASAMKTIAFLA-MAEDTCIAMLGEDVMEAILEAMKLFPGNAPVQK-------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   AG----------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   PGDV--------T-----------------------------------------------
AqueK489_Aque   -------------------IKVSSFHQQLPD---DLFKWGQ---TMLN------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   -------------------SNGA-----DP-------NLPN---SQGN------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   NLSDVYIVTGSTAALSYVLRDHMFAHINLLQLNFHSILFDVLKLHSSNPEIVC-------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   NG----------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   RG----------------------------------------------------------


LRRK2_Hsap      VLFERVSEEQLTEFVENK----DYMILLSALTNFKDEEEIVLHVLHCLHSLAIPCNNV--
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      VLFERVSEEQLTEFVENK----DYTILLSTFGSFRRDKEIVYHVLCCLHSLAVTCSNV--
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   -LFGGSTTN--------RLSNNVYIL--------------------NFTDTSVNCSKLSN
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ---------------EVLMSGNVRCYNI---------------------------V----
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ---------------EVLMSGNVRCYNL---------------------------V----
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ----------AK---LVSKKKPESIFKTLF----------------------SMSTLEMK
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      -------NACNALKQL--LTDEDCY-DVLLQ-----------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   PGGTVQWPKGRHAHSSVLISTSLGPYLL---------------------------V----
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ----------STLLKSTQFGNR--------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ----------TALHVACYYGERECA-SILLHYKAEVNAKGAEGKIPLHRAVLGVCVLE--
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -------NVFLVFRLI--STEDRCK-QVLLE-----------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      LGEDKSAPEIS----EVENQIDDLGILFK-ALEI-------------------------L
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      -------PDIK----TREDAIKLGQTLFD-A-----------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   -----PGPKYQSREQISENQIDLVKLLVGNGSKVTFHDGYGDTPYDAALQCDFYECAELL
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      TNSFNQNKDIEDIV----------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------ET-HKDII----------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   -------------VGGAGTDDIWIFNINNKSWKEQEQVNLPDNATDRCYHSLSVWSVTPT
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ----------SDLA----------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------SSLFQLSL----------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------VEAMKA--FPMSERIQEVSCCLLHRLTLG---NFFNILVLNEVHEFVVKAVQQY
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------VEAMKA--FPTNENIQEVSCSLFQKLTLG---NFFNILVLNEVHVFVVKAVRQY
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------RY----------------------------V-----------
Pats1_Ddis      -------SSFQ--YVGNESE----------------------------I-----------
QkgA_Ddis       ------------------------------------------------K-----------
QkgA_C2d_Ddis   ------------------------------------------------K-----------
Roco10_Ddis     ------------------------------------------------L-----------
Roco11_Ddis     ------------------------------------------------L-----------
Roco4_Ddis      ------------------------------------------------M-----------
Roco5_Ddis      ------------------------------------------------A-----------
Roco6_Ddis      ------------------------------------------------I-----------
Roco7_Ddis      ------------------------------------------------I-----------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      -------AAIKR--FPDNVGLQTACCALIEALAQTE--DSQQLFVLNDV-----------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   TNWIIVF-----------------------------------------------GGSTLY
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------L-----------
AqueK491_Aque   -------NAYDACKVGDLTK----------------------------V-----------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -------EYLQS--YQEDVPVVTSLCSVIESLASTESTDFMELAASVPL-----------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      PENAALQISALSCLALLTETIFLNQDLEEKNENQENDDEGEEDKLF--------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      PENAALQISALSCLALLTETIFLNQDLEERSETQEQSEEEDSEKLF--------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ---------------------------------------------KQFLNKN--------
Pats1_Ddis      ---------------------------------------------ADLVKIV--------
QkgA_Ddis       ---------------------------------------------KDLIVNS--------
QkgA_C2d_Ddis   ---------------------------------------------KDLIVNS--------
Roco10_Ddis     ---------------------------------------------KSLLLA---------
Roco11_Ddis     ---------------------------------------------KDLLVRV--------
Roco4_Ddis      ---------------------------------------------KDLIISV--------
Roco5_Ddis      ---------------------------------------------MDFWVTN--------
Roco6_Ddis      ---------------------------------------------NSLLLND--------
Roco7_Ddis      ---------------------------------------------TDLINSL--------
Roco8_Ddis      ----------------------------------------------GIICNV--------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ---------------------------------------------SDLLIDALR-RFSDN
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   TDTAVIELRYTSNNDWFTSIIPLDQYQEKLQ-ERRNEDKIEIDHLT--------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ---------------------------------------------RDFLYHE--------
AqueK491_Aque   ---------------------------------------------KELMPGI--------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ---------------------------------------------SSLVYSSLQLHYKES
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      -----------------------------------WLEACYKALTWHRKNKHVQEAACWA
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      -----------------------------------WLEPCYKALVRHRKDKHVQEAACWA
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ---------------------------------------SNIPIPPVPTSPTSTPPNLQT
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ---------------------TSTTTTTTTTTSSN-NIPSLVSV----------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ARYLTICLSVMDRLAEAIFTAPKW--LDRMLNDNW-MNETFMALTKHQDSPPCLENALRA
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ----------------------------------HLLQERERELEEERREK---------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ---------------------PNAQAYF--------------------------------
AqueK491_Aque   ------------------------VVMI--------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   VQLCAYGFSLFSYLSSRLPLITNHLRLEDLL--RF-MS---SVFEVHGSDTEFQEAFCRC
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      LN-----------------------------NLLMYQN-SLHEKIGDEDG----------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      LN-----------------------------NLLMYQN-SLHEKIGDEDG----------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     NN-----------------------------NNKQ-------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      LT-----------------------------TLVSNRPGMLVEMLTEESE----------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   -EQVRNRLQQQFQGRERQLQQAQQQGQERERQAREQVQ-DLHRQLREKER----------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   -------------------------------NTKM-------------------------
AqueK491_Aque   -------------------------------NECK-------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   LG-----------------------------GLFEASP-QLHMFVGEGGGGGGEGGGGGG
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------HFPA-----------HREVMLSMLMHS-SS------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------QFPA-----------HREVMLSMLMHS-SS------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------SMAV-----------DSAVLMSLRLHSKNS------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------EFQE-----------REQQLLRQVEGG-QQREQDLQRQLQLREQQLEEREREFQ
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   GGNEESSLSTAGEIRVPIINWIWVVLLSNLSDT-QQ------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      -----------------------------------------------KEVFQASANALST
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      -----------------------------------------------KDVFQAAAHALST
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      -----------------------------------------------KIIFEMGCDAIQA
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ERERQFEEQIQVAESSWVVNRREITMTEVVLGKGGWGEVKVAGFRGLKVAAKCLYEVIIS
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -----------------------------------------------YKVFESVCLAVYY
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      LLEQNVNFRKILLSKGIHLN----------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      LLEQNVNFRKILLAKGVYLN----------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      LAENSDMMQRTLAEKGALMDIRSGMVT--YARSP---ECQAAASRAIRGLCLAIEYRDDS
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   PYNIEIFSRE--------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   LGVDSDRLRKLLLDKGGASAIFEGLRRFKGIQEPRFERCLQYGCRALLALIMS---PGS-
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ----------------VLELMQKHIH----------------------------------
LRRK1_Hsap      ---------------QL-------------------------------------------
CG5483_Dmel     --------------E---------------------------------------------
LRRK2_Mmus      ----------------VLELMQKHAH----------------------------------
LRRK1_Mmus      ---------------QL-------------------------------------------
T27C10.5_Cele   --------------RTP-------------------------------------------
GbpC_Ddis       ---------------LL-------------------------------------------
Pats1_Ddis      ---------------LS-------------------------------------------
QkgA_Ddis       ---------------MK-------------------------------------------
QkgA_C2d_Ddis   ---------------MK-------------------------------------------
Roco10_Ddis     -----------DK--DK-------------------------------------------
Roco11_Ddis     ---------------MK-------------------------------------------
Roco4_Ddis      ---------------MN-------------------------------------------
Roco5_Ddis      ----------------Q-------------------------------------------
Roco6_Ddis      ---------------LN-------------------------------------------
Roco7_Ddis      ---------------IV-------------------------------------------
Roco8_Ddis      ---------------TS-------------------------------------------
Roco9_Ddis      ---------------KK-------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ---------------GF-------------------------------------------
LRRKb_Spur      IHLDNKQAVTEAGIHTL-------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   --------------N---------------------------------------------
AqueK486_Aque   -----------------MNIASKLRHPNLLQFIGATTEVMAGVFRGVFQDDANLHKFCHD
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   --------------TFL-------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   -----------TKGNTL-------------------------------------------
AqueK491_Aque   -----------KEYMTL-------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   --------------RTL-------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   --------------YTL-------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ---------------------------------LSI------------------------
CG5483_Dmel     ---------------------------------LRT------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ---------------------------------LSI------------------------
T27C10.5_Cele   ---------------------------------LML------------------------
GbpC_Ddis       ---------------------------------KKK------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ---------------------------------DEK------------------------
Roco7_Ddis      ---------------------------------ILD------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ---------------------------------LHA------------------------
LRRKb_Spur      ---------------------------------LFEAVRNFIGDVEVLLDIVNTITCLAD
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   GKIEKIMDFVATVEPEILLDRLNNRRGISGYTPLHE------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ---------------------------------LFP------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ---------------------------------IHE------------------------
AqueK491_Aque   ---------------------------------LMI------------------------
AqueK492_Aque   --------------------------GVFGYTPLHE------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -----------------------------------SGMKDFLVQVEA-------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ---------------------------------VHI------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ---------------------------------LHY------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      MDVVKYQCMVEGIHEVILQGMAEYQDDPNIQELFLETMVVLSSAEGMIDILVEAGILSLT
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      VELMEKYSQIEAIQENGTILLQTVVNKKKSICDDRLAEKIARAIISSMKKFRKAPSILAE
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------------------------------IYDLIDILDNHTAAPDIAAE
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      SCVAMQFLADISQEVTKTLVNYNAHEELFHILEAYKDDDTLVNLVCECLYILCCKWEFTD
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ALGV-----------------------MACLSDNGRFRAAAIQQN---------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ----------SPEVAESGCKMLNHLFE-GSNTSLDIM----AA--------VVPK-----
LRRK1_Hsap      -----PAAYGD-------LEMVRYLLSKRLVELPTEPT----D--------DNPA-----
CG5483_Dmel     -----AVISGD-------ERTVRVLLAALGT------------------------ERQ-I
LRRK2_Mmus      ----------APEVAESGCKMLSHLFE-GSNPSLDTM----AA--------VVPK-----
LRRK1_Mmus      -----AAAHGD-------LETVQFLLTEKRVELPTEPT----D--------DNPA-----
T27C10.5_Cele   -----AAHNGK-------LDSLRTILMLSPN-----------------------------
GbpC_Ddis       -----DGTLGT-------AEELLTLIQQSNINVVTAST----------------------
Pats1_Ddis      -------------------------------------------------------NNDGL
QkgA_Ddis       -------------------------------------------------------NH---
QkgA_C2d_Ddis   -------------------------------------------------------NH---
Roco10_Ddis     -------------------------------------------------------DN---
Roco11_Ddis     -------------------------------------------------------NI---
Roco4_Ddis      -------------------------------------------------------SL---
Roco5_Ddis      -------------------------------------------------------NN---
Roco6_Ddis      ---------------------------------RTTST----------------------
Roco7_Ddis      -----DSF----------LELLRLFIKQTIDQAKQCST---DE--------SNPLNY---
Roco8_Ddis      -------------------------------------------------------GA---
Roco9_Ddis      -------------------------------------------------------DK---
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -----SCKKGD-------VDAAHMLMCWGIEPCCKNTE----G--------RSAL-----
LRRKb_Spur      QMLLWACKENL-------MKGVEVLVELGADVN-----TGEGY--------ETPM-----
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------QRYITGSVKMCGR------------------------EV---
AqueK486_Aque   -----AVSGNR-------YEVISYLVELGANVNARAN----FG--------YTPL-----
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   -----AAKAGQ-------PDTLEKFIRYGDLSQIEKDDKSHLG--------WNIY-----
AqueK489_Aque   -------------------HVVSLLIKFGANNYKECID---S------------------
AqueK490_Aque   -----AVENGQ-------PDVLQLLLQNGI-SSETKGK---NN--------QTPL-----
AqueK491_Aque   -----ASREGH-------SAIVDYLIDIGAKVTHTLGS---TA--------KTAL-----
AqueK492_Aque   -----AVSGNR-------LKVIPYLIEQGANVNAKAN----SG--------YTPL-----
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -----------------------------------------VHARVLNLIQYKPT-----
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   -----AADKGL-------SEYLEKLLLEGGDPNKPSSV-PDLC--------QTPL-----
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----AAERDR-------PESLKILLINGADPNIRTSH-NSFE--------ITPL-----


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      SSNSNNNSSSNIGSMLNSGGGGSGSNLGLGLSSGTGGSFNGNSSGSSSSSSYYYNNNNNN
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     --------------IVNMA------------PS---------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   --------------SLNLV------------ND---------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      NNIELTAQQKNPKVLCSFI------------LH--LLQ----------------------
QkgA_Ddis       ------------ETTLTII------------NE--TYR----------------------
QkgA_C2d_Ddis   ------------ETTLTII------------NE--TYR----------------------
Roco10_Ddis     ------------ETFATLI------------NE--ELP----------------------
Roco11_Ddis     ------------NTPFKIL------------NE--TFK----------------------
Roco4_Ddis      ------------DTTFKII------------NE--TYR----------------------
Roco5_Ddis      ------------NTSNNNI------------NN--NNK----------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------QSFYNLI------------NR--MAA----------------------
Roco8_Ddis      ------------D---PIF------------KD--DYI----------------------
Roco9_Ddis      ------------EK--KILQQLQQQQDDEQQQQQQQFMEGDNNNNNTNSLNTPSVEGDSE
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   --------------PVKIV-----------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------ILTVMKRHETSLPVQLEA------------------------
LRRK1_Hsap      ------------------VVAAYFG-------HTAV------------------------
CG5483_Dmel     ------------GANTLLFLACQSG-------YESI------------------------
LRRK2_Mmus      ------------------ILTVMKAHGTSLSVQLEA------------------------
LRRK1_Mmus      ------------------VVAAHFG-------HAEV------------------------
T27C10.5_Cele   ------------RGKTALHMAAESG-------ETSI------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -----------I------------------------------------------------
QkgA_Ddis       -----------I------------------------------------------------
QkgA_C2d_Ddis   -----------I------------------------------------------------
Roco10_Ddis     -----------L------------------------------------------------
Roco11_Ddis     -----------I------------------------------------------------
Roco4_Ddis      -----------I------------------------------------------------
Roco5_Ddis      -----------TSNTTGSNVSSSNN-------KETVKINVTSLDSGGNNNASGKDISNEH
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      -----------I------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      NINRLAASTNST------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------EIATTEG-------HLNI------------------------
LRRKb_Spur      ------------------CFACEN------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   -------------------EEPELT-------TRAI------------------------
AqueK486_Aque   ------------------HLAASAG-------HIEC------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------HYAVY-------------------------------------
AqueK489_Aque   --------------------SRQNN-------HI--------------------------
AqueK490_Aque   ------------------HIAAAKG-------HVDC------------------------
AqueK491_Aque   ------------------HYAAENG-------HADV------------------------
AqueK492_Aque   ------------------HLAAIVG-------HIEC------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------HSVLVE------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------HLAAFQG-------YAKC------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------HIAAANG-------HLDC------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ---IFSQTSLTYSLYITY------------------------------------------
QkgA_Ddis       ---V-------------Y------------------------------------------
QkgA_C2d_Ddis   ---V-------------Y------------------------------------------
Roco10_Ddis     ---T-------------TEE--KENIKAQKKD---------------------------L
Roco11_Ddis     ---N-------------Y------------------------------------------
Roco4_Ddis      ---V-------------Y------------------------------------------
Roco5_Ddis      SPKN-------------RKEKEKEKDKDNKEDSINESPVDENRRKLVEGFMKSLQGCSDA
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ---Y-------------L------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ---S-------------Y------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      VQE---------------------------------------------------------
CG5483_Dmel     TQRLLDAGADGRSHAVTKYSP---------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      VRE---------------------------------------------------------
T27C10.5_Cele   VLELVELGSDPMKSDNEGHCA---------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ISS---------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      IKV---------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ITE---------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   L-----------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   -TA---------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   IKT---------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ----------------------------------TLLMEDIGP------LPDGVIKDNS-
AqueK496_Aque   LQVLVKHGAQIRVQNAHRTTPIDLVRGK--TVCESILQEAIGKVEVPNRTQDQLQR--V-
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   LKRLVESGGDPLLRDSKNRLPRDHAQGNRQELCLEYLQKESA-----TVIKSGI-SEPLT


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   --LAVIVLFC----------------NKKE------------------------------
AqueK496_Aque   --MDLHRLID----------------QQRE------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   TIFYLVIMADVSEYLEAGDFESLFNYDNFNKSFPLDSSKPTPTTPEDNIIERQEIHTFIL


LRRK2_Hsap      -------------------------------------------------------LRAIL
LRRK1_Hsap      ----------------------------------------------------------LL
CG5483_Dmel     -------------------------------------------LYAAVHSGHLGIARLML
LRRK2_Mmus      -------------------------------------------------------LRAIL
LRRK1_Mmus      ----------------------------------------------------------LL
T27C10.5_Cele   -------------------------------------------LELAQMAGHNEVAAKLI
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ----------------------------------------------------------LP
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ----------------------------------------------------------I-
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------------------------------------------------LV
LRRKb_Spur      --------------------------------------------------NNVDMVKQLL
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   -------------------------------------------------------VKALL
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   --------------------------------------------------GYQINCSYLL
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ----------------------------------------------------------LI
AqueK492_Aque   -------------------------------------------------------VRVLL
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   --------------------------------------------------SAI---ELLI
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ----DMDTFM---SLYSRLSALETDLSTRWTDW-----FQQTLLYRAADKDHVQIVTFLL
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   NTYTKHCNLLNNSTLVHSL--------SRFTRDFPISLHYVTILHAAVQYNHISLVSFLV


LRRK2_Hsap      ----H---------FIVP------------------------------------------
LRRK1_Hsap      ----E---------SL-P------------------------------------------
CG5483_Dmel     ----D-------------------------------------------------------
LRRK2_Mmus      ----H---------FVVP------------------------------------------
LRRK1_Mmus      ----E---------SL-P------------------------------------------
T27C10.5_Cele   ----D---------AI-Q-KES--------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     EVPL--------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ---LD---------VF-Y------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----K---------ID-E------------------------------------------
LRRKb_Spur      ----K---------QG-ISDLHTPLSRCLKLKQHHIIGLLLYQMGCDRQAGSLTWSSLGL
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ----Y-------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ----N---------EK-SQAST--------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ----K---------RL-P------------------------------------------
AqueK492_Aque   ----D-------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----IFAQLDEKVHTV-FNE----------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ----Q---------QS-PAQPL--------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ----S---------NY-P------------------------------------------


LRRK2_Hsap      --------------------------------------------GM--------------
LRRK1_Hsap      --------------------------------------------G---------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      --------------------------------------------GL--------------
LRRK1_Mmus      --------------------------------------------G---------------
T27C10.5_Cele   --------------EDLNEAHTMIISACISGSADVVYE-ISR---RFMEKSGKQSREILF
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      --------------------------------------------QP-LKKADLLSQ----
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      --------------------------------------------G---------------
LRRKb_Spur      ARLNPEWLYKVFLDEEPPDPDSPND-----VVKYQCMVEGIHEVI---------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   -------------------------------------------------------SIILF
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   --------------ANLT-PDEARQ-----I-----------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   --------------------------------------------R---------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   --------------------------------------SGIFREL---------------
AqueK495_Aque   --------------HKEE-EQKTINTNDATDEIELFFKAFSDKPK---------------
AqueK496_Aque   --------------SNLGHGDTPLMIACRHSNLKLVDLLINHSPG---------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   --------------------------------------------S---------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   NGRNEEDETA--------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      --------EELKAIFSLIESISSFQQTILIDFKKYISNWNSTTQAQLHSTFLQFVGYLKL
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      --------------------------KSQLGGLMEKT---------MISQVLNFTPMIQE
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      -----------------------------------------------------SSLRSSS
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   DITSHETYME--------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      --PEESREDTEFHHKLNMVKKQCFKNDIHKLVLAALNRFIGNPGIQKCGLKVISSIVHFP
LRRK1_Hsap      -PC---------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      --LEESREDSQC--RPNVLRKQCFRTDIHKLVLVALNRFIGNPGIQKCGLKVISSLAHLP
LRRK1_Mmus      -PC---------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      YKV---------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      QIV---------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      TRS---------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -LL---------------------------------------------------------
LRRKb_Spur      -LQ---------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   -----------------------------CSADISLIDSRGKTPKQTADLKKKSNVVRLL
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   -IL---------------------------------------------------------
AqueK492_Aque   -----------------------------CSADVSLTDDYGKTPRQTASLGKNSNIVRLL
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -IA---------------------------------------------------------
AqueK495_Aque   -LF---------------------------------------------------------
AqueK496_Aque   -LI---------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -LL---------------------------------------------------------


LRRK2_Hsap      DALEMLSLE-GAMDSVLHTLQMYPDDQEIQCLGLSLIGYLITKKNVFIGTGHLLAKILVS
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      DATETLSLQ-GAVDSVLHTLQMYPDDQEIQCLGLHLMGCLMTKKNFCIGTGHLLAKILAS
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   RSEEIIKEAKTKGDNLTELLEVRIDDLE--------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   RSKEIIKEVKTNGDNLTELLRVRIDDLE--------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      SLYRFK------------------------------------------------------
LRRK1_Hsap      -----S------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      TLQRFK------------------------------------------------------
LRRK1_Mmus      -----T------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------L-----------------------------------------------------
QkgA_Ddis       ------Y-----------------------------------------------------
QkgA_C2d_Ddis   ------Y-----------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------C-----------------------------------------------------
Roco4_Ddis      ------F-----------------------------------------------------
Roco5_Ddis      -----YG-----------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      -----IL-----------------------------------------------------
Roco8_Ddis      ------F-----------------------------------------------------
Roco9_Ddis      -----ID-----------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -----E------------------------------------------------------
LRRKb_Spur      -----GMAEYQDDPNIQELFLETMVV---LSSAEGMIDILVEAGILSLTVELMEKYSQIE
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   -----LY-----------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -----ILDRNMGESITYKCL-----MLIHILADED----------------HLSTYPRDC
AqueK495_Aque   -----VIGDNKPDTCQ----------------WPEAAQFVML------------------
AqueK496_Aque   -----FI-----------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----T------------------------------------------------------


LRRK2_Hsap      ---------------------------------------------DVAEIQTKGFQTILA
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ---------------------------------------------DVAEVQTTGLQTTLS
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      AIQENGTILLQTVVNKKKSICDDRLAE----KIARAIISSMKKFRKAPSILAESCVAMQF
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   --------------------------RKIAWSLCSLLAPTQQSPTLTIEARIATAITLTF
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ILKLS-------------ASFSKLLVHHSFDLVIFHQMSSN-------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ILELS-------------VSFSKLLVHYSFDVVIFHQMSSS-------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ----------------------------------------------------LLIEISHF
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ----------------------------------------------KTN-----------
QkgA_Ddis       ----------------------------------------------DQY-----------
QkgA_C2d_Ddis   ----------------------------------------------DQY-----------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ----------------------------------------------DQQ-----------
Roco4_Ddis      ----------------------------------------------DTD-----------
Roco5_Ddis      ----------------------------------------------LQY-----------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ----------------------------------------------ANK-----------
Roco8_Ddis      ----------------------------------------------YQF-----------
Roco9_Ddis      ----------------------------------------------YNP-----------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      LADIS-------------QEVTKTLVNYNAHEELFHILEAY-------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ----------------------------------------------------L-SQLLEM
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------QLDIIYLLHQ-HKAPVT---AGLDIEQEDI
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ----------------------------------------------EE------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   LIHIDALVCACSLCKSCPNLMPQILVEFAVDTNIFRLLYSKPLEDLQFDNTD--------
AqueK495_Aque   --------------------------------------------DDITQP----------
AqueK496_Aque   ----------------------------------------------SEDQ----------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   SFEICFHKNLFQCLHKRSYRNRPSLITIRRASSTKPRIQGYSNPCGSVVTECGSVAAVFG
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------KDDDT-LVNL--------VCEC--------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   SHRVCPSAHVVVI-GAKADLRKP------HHVTTE---EAESFC----------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   LHPLPLHPSLMALGFECSFSEAAILIDMLSLSSSTAGSNGVG-----------------S
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----TDNPEQL-IYEL--------AIDV--------------------------------
AqueK495_Aque   ---EELNKLF----------KTIILEPLLFS-----------------------------
AqueK496_Aque   ---NSLSPLHVS----TSRGDKGIVQSMLDA-----------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     -------------------------------------------HFPEL----------IQ
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   VS-PSPVSNGGPFRDGEELENRRNRAFDISLWCLKILKLQIFQKFPQL----------VK
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      --------------------------------------------LYI----------LCC
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   HSAS----------------------------------------TPG--LDNIKVTSNND
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   --------------------------------------------VHS----------LSL
AqueK495_Aque   --M---------------------------------------------------------
AqueK496_Aque   --VQ------------------------------------------GLYEKGITHRDLNL
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      PQRL--------------------------------------------------------
CG5483_Dmel     QPTV--------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      PQRL--------------------------------------------------------
T27C10.5_Cele   STNN--------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ---N---------NNNNNNNNNSSSPSNTDL-------------SRSTYFYDIP-VKSRI
QkgA_Ddis       ---E--------------------------------------------------------
QkgA_C2d_Ddis   ---E--------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ---E--------------------------------------------------------
Roco4_Ddis      ---E--------------------------------------------------------
Roco5_Ddis      ---N--------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ---EAN----KNN-----------------------------------------------
Roco8_Ddis      ---DNN----KNNNNINNNNNNATSTATT-------------------------------
Roco9_Ddis      ---SNNGGNGGIRSDSFYSQTSESSDITSTSTTSPTMSAASSSSSSGTVKTPKPPKSSKL
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      DVAE--------------------------------------------------------
LRRKb_Spur      KWEF--------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   HRRA--------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ---S--------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   KEDC--------------------------------------------------------
AqueK495_Aque   TQTD--------------------------------------------------------
AqueK496_Aque   TDKI--------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   QPSS--------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ILKHIMLFLYNLTQRDASLLDSLSNIIGPFILGNVLLDPPPPPPSNSSPPISKSTS-NNN
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------ATAPITPVSTKIGSIGKSSS----
Roco9_Ddis      --KHIYNSLKFKSLKTEKNGSSSSIKSNISNFEFIMPNTPLPIFDQQSPPIHF-YNSNQ-
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      LNV---------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      FSDFQYFGTPLYSLIKRQDNGLSIPILLEKSISFLEGHCHVEDLFFRKYNNEKVKFMRNS
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      FERTGDFNFYYPDPQDPYDVAALLVEFIASLPDQLLNVELYNAIKNHTSALNSQYGGYWD
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ----------------------------------------LN-WM---------------
CG5483_Dmel     ----------------------------------------ERWLP---------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ----------------------------------------LN-WM---------------
T27C10.5_Cele   ----------------------------------------EGSTC---------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ---------------------------------------SN-YHNNNNNNNNSNSNLSNS
QkgA_Ddis       ---------------------------------------SK-FTS---------------
QkgA_C2d_Ddis   ---------------------------------------SK-FTS---------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ---------------------------------------TK-TKSS--------------
Roco4_Ddis      ---------------------------------------TK-LTSSNLDS--DDEEFESD
Roco5_Ddis      ---------------------------------------YS-LSS---------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      IQYLAQKLSVESREFLQRLLFFLKKHVSACLFKQQQQQQQQ-RES---------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------------------------------LK-LL---------------
LRRKb_Spur      ----------------------------------------TD-QM---------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ----------------------------------------LY-HL---------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ---------------------------------------PK-GSS---------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------------------------------RQ-KM---------------
AqueK495_Aque   ----------------------------------------ID-KV---------------
AqueK496_Aque   ----------------------------------------GR-TP---------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ----------------------------------------EGYTA---------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      --------------LALACQRGHLGVVKLL------------------------------
CG5483_Dmel     --------------LHAACINGHIKLLELLISYSYPDYLYQTYRDEEG------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      --------------LALACQRGHLEVVKLL------------------------------
T27C10.5_Cele   --------------LHWAARCGSSECVSTILNFPFPSE-FIIEIDTVG------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      GNGDESPDFQSQNLVKSYN-----------------------------------------
QkgA_Ddis       --------------CNIIT-----------------------------------------
QkgA_C2d_Ddis   --------------CNIIT-----------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     --------------FYIQT-----------------------------------------
Roco4_Ddis      DDADEEADLQIQASCNLYT-----------------------------------------
Roco5_Ddis      --------------LCLLM-----------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      --------------NNVLS-----------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      --------------TEVL------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      --------------VCRACKAGKKEIIDYWF-----------------------------
LRRKb_Spur      --------------LLWACKENLMKGVEVL------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   --------------FEWAYNRGHLDVLTFC------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   --------------LHLAA-----------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   --------------LISAVKHSMIEAIKLL------------------------------
AqueK495_Aque   --------------SSLACVKGESNTLKLFLGLH---------------------QTPPT
AqueK496_Aque   --------------FYNACYHGQLPIVKAFLEFK---------------------AKFPD
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   --------------LHVAVSHKCFEIVQILTEAY-MNI-YRQRS---SSVALAMGGANPR


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     --QWEWR-----------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   --APAYQ-----------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------RE-----NSGNSLNSMLHQTSLPNNNNS--------------------
QkgA_Ddis       ------------FDGKDKRS-------------------IK-------------------
QkgA_C2d_Ddis   ------------FDGKDKRS-------------------IK-------------------
Roco10_Ddis     ------------FISPSPTL-------------------SRNNNGKRNSGGNKPPLSPIK
Roco11_Ddis     ------------LDANDKSS-------------------LE-------------------
Roco4_Ddis      ------------FDGKNRQS-------------------VD-------------------
Roco5_Ddis      ------------FDNQRFES-------------------FINNAESKLVNEHKYSLAPLV
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------ANSTPNV---------------------T-------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ----------------------------------------T-------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------RNG-HADT-------------------VK-------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   N-------TWL-------------------------------------------------
AqueK496_Aque   K-------IDINA-----------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   IRAPPSEAPLLFS-----------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ---------------------------------------------------------GG-
Pats1_Ddis      ------------------------------------------NVV-----NNNNNNNNNN
QkgA_Ddis       ------------------------------KM---------KRVV-----QKLSNESTN-
QkgA_C2d_Ddis   ------------------------------KM---------KRVV-----QKLSNESTN-
Roco10_Ddis     --ISSTSAAGDVSPSISLNNSGSGIYNSTSP--SGTASTQT-LNILSQLQQQQRNGNNNN
Roco11_Ddis     ------------------------------LT---------KSAI-----KNIQMQQQQQ
Roco4_Ddis      ------------------------------EI---------KRIV-----QHLNETQ---
Roco5_Ddis      PTSSSSSCVKPVSLSEI---------------------------LGSQYDQTTSQSTNNS
Roco6_Ddis      ---------------------------------------------------------NNK
Roco7_Ddis      ----------A--------------------LKTSPA-IGSPRII-----M--GSNYNNS
Roco8_Ddis      ------------------------------KS---------STAV-----DKMNNNNNNN
Roco9_Ddis      ----------LSLSSSTSTLEPEPQPLPLSTS---------TQRLPQQSSDDNSNNDNNN
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------VL---------LDVA-----SGLFPP----
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       AAMG-------------------------------AMLNHTVS-----------------
Pats1_Ddis      NNNNNNN----------------------------NNNNNNNNNN---------------
QkgA_Ddis       ---SSHQ----------------------------FD-----------------------
QkgA_C2d_Ddis   ---SSHQ----------------------------FD-----------------------
Roco10_Ddis     NNNNNNNYLSSPTMPALNKHSTHGNFHNSVAGYGNNNNNNNNNNKQPQHPMNGNHSPSNG
Roco11_Ddis     QQQQQQQ----------------------------QQ-----------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      SG---------SSFPAVTLRRTGHTFTGIN--SANSNNNNNNSG----------------
Roco6_Ddis      SNNN-------------------------------SNNNNNET-----------------
Roco7_Ddis      SNNNNI-----------------------------DSIDLNNNSP---------------
Roco8_Ddis      NNNNNN-----------------------------NNNNNNNNSN---------------
Roco9_Ddis      KNDNDN-----------------------------DNDNDNNN-----------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ----------------------------TPERK---------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      --------------------NNNNNNINNNSTSSNNNNNNNSNNNN-SQI--------P-
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     TSGSLSMSGSGIDNGGNNNNNSN--------------THGSSSNQ-SSGV----------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      -----------GGSSGINNSNS---------------------------VTGKFTQEYT-
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      --------------------NML--------------KNNSPSTFINGSV--------PQ
Roco8_Ddis      --------------------NSN--------------SNNNSSRRT-SSV--------P-
Roco9_Ddis      ----------------------D--------------N-NNINNDNGEII--------P-
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   --------------------------------------------DSSSLD----------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     --------LPFDA-----NAHDVTGQ----------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   --------LALDV-----NEVDGECR----------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -----PLI----------------QVRQPSSDFTTTS-----------------SGNLRS
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      INGGGGSY----------------NLTPI-------------------------------
Roco8_Ddis      -----PPV----------------LVTAS-------------------------------
Roco9_Ddis      -----PSI----------------QVTPPTSPQTQPKQQQPPQPPQKTLIEKLSE-----
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   --------------------SGHRNG----------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   -------------------------F----------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   -----EPVLPPDASVNVFSHSQAEGR----------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   --------------------EEKSRR----------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   --------------------PTNTGH----------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     --------------TSLYIASILGN--KQLVGVLLKWQ----LHCRR-------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   --------------TAMYLAVAEGH--LEVVKAMTDFK----CT----------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      LSNTENSLCKKVAID------------------LIQNIPLYLLFSHLKIQQLEGEKILFS
QkgA_Ddis       ------------------------------------------LHSHA-------------
QkgA_C2d_Ddis   ------------------------------------------LHSHA-------------
Roco10_Ddis     ---------------------------------------TSP------------------
Roco11_Ddis     ------------------------------------------QQHHD-------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      -------------YS------------------NLASLLILPI-----------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   --------------TPYY------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   --------------LKICQAILDEE--EDVIDILLARN----------------------
AqueK490_Aque   --------------------------------------------LRA-------------
AqueK491_Aque   --------------TPLHEAVIGGH--TDIVSMFVKWIRENQLKKPV-------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   --------------SPLHAAVSAPKFSKEIVELLVK-EEELKLNIE--------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   --------------TPLHMSVALCE--REITLLFLSHAKQLSLSLE--------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------T------------LGDSASSVSTPITPTRKRISFGIQAIMSK
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      AENIFCVDKCNFPPNK-AMLGEIWVTNFRIIFINSN------------------------
QkgA_Ddis       ------------------L------------LQ-SS------------------------
QkgA_C2d_Ddis   ------------------L------------LQ-SS------------------------
Roco10_Ddis     ----------------------I--------IQ---------------------------
Roco11_Ddis     ------------------I------------FQ-FT------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ----------HFLARFHQFFKSL--------ID---------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      -------------------------------LS-SS------------------------
Roco9_Ddis      -----------------LFTPLF--------VN-YK------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------L------------LE-GG------------------------
AqueK491_Aque   ------------------A------------L--GL------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   -----------------------------------A------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----------------------------------G------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     LHISGESEGPDDLASQESTECQRCPINVNLLCGAARETALLAAVRGG-------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ----------------SIDGRQRCPFQLDVYCTR-GRTPFMLAAFNQ-------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------EIANG-------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   --------------------------------YPSSRSHKYIAKMLERKRSLTVFPSSSI
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   --------------------------------SACGYTALHLAVHFN-------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       -------------------------------------------------TINL-T-----
Pats1_Ddis      ----------------------------------SNSSTIPN----STSSTSI-------
QkgA_Ddis       ----------------------------------SSSSSS-S----TSSSPSL-------
QkgA_C2d_Ddis   ----------------------------------SSSSSS-S----TSSSPSL-------
Roco10_Ddis     ----------------------------------STSPQPPH----LTGLN---------
Roco11_Ddis     ----------------------------------QPSSSH-N----HS------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ----------------------------------SIAVLNPD----YKPYN---------
Roco6_Ddis      -------------------------------------------------LEDI-I-----
Roco7_Ddis      ------------------------------------SSPT-I----GSSTPTIITS----
Roco8_Ddis      ----------------------------------TSSSSSST----TSTSSSL-------
Roco9_Ddis      ----------------------------------THSAFYSS----TSTLITS--CEDIF
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ----------------------------------ADINST-DDFGNT-------------
AqueK491_Aque   ----------------------------------SPSSALS-----NSQVPVS-------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   AQTYRAYTSFDQIESDDPPSYRDDRGCDTPISTSSAISDDLDAEIGITKRESL-------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      VHIDERPITLPGEFIMMQIKNVIIPPTNLKLEHTISSSSKSDKNDKNDKNGNTDVTLWQS
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ----------------------------------------SSFASTQNLSILSIMTLFGS
QkgA_Ddis       ----------------------------------------T-------------------
QkgA_C2d_Ddis   ----------------------------------------T-------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ----------------------------------------S-------------------
Roco8_Ddis      ----------------------------------------A-------------------
Roco9_Ddis      GTLFITNYRMIWKKDESNSIDSESNSILLPEDIITPTQSFS-------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   -----------------------------------------VFSRAERSKRREPIQRLLK
AqueK491_Aque   ----------------------------------------P-------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ----------------------------------------P-------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ---------------------------H--------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ---------------------------N--------------------------------
GbpC_Ddis       -----------------------GSGSVPTYNPSDN----R-------------------
Pats1_Ddis      YNGNGGSGPTNATLSGGGSTSSSSNLNTPITTSP-------IH--TS-------------
QkgA_Ddis       -----------------------SSPSSPISTSP------PYH--SS-------------
QkgA_C2d_Ddis   -----------------------SSPSSPISTSP------PYH--SS-------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     -------------------------------NHH------HHH--HQ-------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      -----------------------EFNN-------NN----C-------------------
Roco7_Ddis      -----------------------SSTTTPTNNNN------SNN--NT-------------
Roco8_Ddis      -----------------------ST---NTNSNS-TYNSNSFNKKHHRYSI---------
Roco9_Ddis      -----------------------S-----INNNN-NNNSS------KFVEIKLYSFEIIL
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ---------------------------P--------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   SKELVLVAC---------------------------------------------------
AqueK491_Aque   -----------------------RTPTTPSSHGL------GLHA----------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   -----------------------HTPIS--------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ---------------------------Q--------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      TSIIKWESFGKSLKSTTPMMSTPTTFQNGGVNRSQFQIFLCYCKNIRFQYMGFSDESNFR
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     -L----------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   -L----------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -TNSNGAILNPINNSLINSNNNNNNNNINNNINNNINNINNNINNINSNSNNNINSIINS
QkgA_Ddis       -P----------------------------------------------------------
QkgA_C2d_Ddis   -P----------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     -Q----------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      -P----------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      DLEKLNLILAYYINPLIDFGRYFSSVN---------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   -T----------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -P----------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     -----------------------------------------------------------D
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   -----------------------------------------------------------P
GbpC_Ddis       -----NSGSH-V-----------------------------------------------I
Pats1_Ddis      NSNNNNNNNNLNKLSTLDN---TEIPLSMIYRWKMVKTGSLYDSFKIYCKDFRCKIIGFQ
QkgA_Ddis       -----------------------------------------------------------Q
QkgA_C2d_Ddis   -----------------------------------------------------------Q
Roco10_Ddis     -----------------------------------------------------------S
Roco11_Ddis     -----------------------------------------------------------Q
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      -----------------------------------------------------------N
Roco6_Ddis      -----NGDMKYL-----------------------------------------------D
Roco7_Ddis      -----------------------------------------------------------I
Roco8_Ddis      -----------N-----------------------------------------------E
Roco9_Ddis      -----------N-----------------------------------------------E
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   -----------------------------------------------------------E
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   -----------------------------------------------------------K
AqueK491_Aque   -------------RASSGSSSNPLDIM---------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----------------------------------------------------------E


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ----VLTH--GADP---------------ESYA---------VRK---------------
CG5483_Dmel     VVQSLLQH--GANP---------------NIVA-----------KPV-------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ----VLTH--GADP---------------ENYA---------VRK---------------
T27C10.5_Cele   LMTLLLDA--GADV---------------NLPL-----------AVL-------------
GbpC_Ddis       TSTN-------------------SVISNSSI---SSTGVIN-------------------
Pats1_Ddis      INSHVLVKF---KD---------------LLTK---------CSVP---TLD--------
QkgA_Ddis       LLEHLLHQQ---QP---------------ITSV---------GSKP---SFF--------
QkgA_C2d_Ddis   LLEHLLHQQ---QP---------------ITSV---------GSKP---SFF--------
Roco10_Ddis     DSQMPLSSS---PTMGYPRGNHNKKTSASA------------------------------
Roco11_Ddis     LQQQ-QQQQ---LQ---------------QQMK---------TPKL---LFF--------
Roco4_Ddis      ------SQQ---ND---------------NQAV---------PVIP---TFF--------
Roco5_Ddis      LYKQIVQVV---KDIVNESVNINKVISIS-------------------------------
Roco6_Ddis      LSKRMIYSL--------------ELMMIPEIENRFQGDFKS-------------------
Roco7_Ddis      ISQTIIQNI---N----------------VEHMKDQISQFSISIIN---TIFRSIEKFPP
Roco8_Ddis      LSKVVLEDL---NT---------------V-TL---------VKDE---LIQ--------
Roco9_Ddis      IPRAPLL-----------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      --DQLIRH--GHLL----------------------------------------------
LRRKb_Spur      -----VEL--GADV---------------NTG----------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   SISALFK-----------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   -----HNRYLSLCS---------------ESLR---------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   SDNHILEKK---LTY--------------FAST---------GTKP---DMR--------
AqueK491_Aque   ------------------------------TEM---------GRT---------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -----VRI--GADV---------------NSSN---------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ---PLMQS--MALP---------------SPSA---------SIPPPSSQIR--------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   MAALLLSN--GANP---------------NATL-----------A---------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ----------------------------------------VSSQNRSPL-----------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------KSIKSPTI----------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      TVFQLFEMLYLDIHQVFSPDFCFELMKKIFFTKLICPILAN---LKSPPNMANGKFFTKT
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------PLHE--------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------TI----------------------------FAYNSK---------ESSFG----
QkgA_Ddis       ------VII---------------------------NLYNDD---------RQSYM----
QkgA_C2d_Ddis   ------VII---------------------------NLYNDD---------RQSYM----
Roco10_Ddis     ----------MNSTGVSSSSSGV-------------------------------------
Roco11_Ddis     ------IVM---------------------------SVG--V---------GKSYI----
Roco4_Ddis      ------VVV---------------------------NIG--V---------GPSFV----
Roco5_Ddis      --------GLFNSSD-------IVQNRKFLKEGILIEQFNNQ---------RISYYTFLF
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      YIEISKVVL---------------------------DIA---------FDRDQSRR----
Roco8_Ddis      ------LSQ---------------------------ELMNGDKGLKLQKKKKGAAG----
Roco9_Ddis      ------------------------------------ANNNNSSSNLISLGRSGITN----
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ---------N-TECF---------------------------------------------
QkgA_Ddis       ---------SEIVSF---------------------------------------------
QkgA_C2d_Ddis   ---------SEIVSF---------------------------------------------
Roco10_Ddis     ---KQAGAGEKVMQFLGKMSLSKERMSKLVSQSKEQYKTPSSPYQQSTSSSISSGSGTIS
Roco11_Ddis     ---------KNIKEE---------------------------------------------
Roco4_Ddis      ---------SEIKSA---------------------------------------------
Roco5_Ddis      SDIILFTEKIEDTSTI--------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      -GSVTTQEQI--------------------------------------------------
Roco8_Ddis      ---------TTISCF---------------------------------------------
Roco9_Ddis      ---------TSTANINGSNRNSV-------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------ASR---------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ----------IICSN---------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ---------------------------PDHS-----------------------------
QkgA_Ddis       ---------------------------AGSF-----------------------------
QkgA_C2d_Ddis   ---------------------------AGSF-----------------------------
Roco10_Ddis     GHTSPNSLNSVQVVPF-----------EGI------------------------------
Roco11_Ddis     ---------------------------AGTI-----------------------------
Roco4_Ddis      ---------------------------AGTT-----------------------------
Roco5_Ddis      --------NNNTMMAY-----------DGSF-----------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------M-----------------------------
Roco8_Ddis      ---------------------------SG-S-----------------------------
Roco9_Ddis      --------------GGNGSHDYTTNIWDI-YSPLIEGQRLKLDLDKDWRVVEFLSRDTST
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------D-----------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ---------------------------LGFT-----------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ---------------------------NGRL-----------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      IYPKRILIPNLIGDELLQSYVRKTQSKIPIFSWSNQNNKSMLFRICVYNQPFNNKFNSGG
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      -----------------HFIKGMIFRNTHSISMTAALNPT----LNNQVIPPSIPLPSKE
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      TLAYNNNSTIINNNSVIITNSSTIGTNTSGIS-------NSNHLIVGEIEPPS-PIKKRQ
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      EACNNFI----------NNIRSESSELEESFKRAKD-----------------------L
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ----QQIVDKKDTSSPLS-----------SLRSSKGIPSKSSKKDKQGFLSSSTSSIIPI
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      -----------IMEQK----------------------DQQFL-----------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     -------------EDH--------------------------------------------
LRRK2_Mmus      -----------VVEQK----------------------DEQFL-----------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -----------LLQEYNRIGVSWDLWRTTTQSKLCEH-YPPTS-----------------
QkgA_Ddis       ------Q----FIEWR--------------------N--DESW-----------------
QkgA_C2d_Ddis   ------Q----FIEWR--------------------N--DESW-----------------
Roco10_Ddis     ----------------------------------------------FGIPLRVILRYPNE
Roco11_Ddis     ------P----ILEWFT-------------------N-YIRSW-----------------
Roco4_Ddis      ------Q----FIEWIV-------------------N--DQAS-----------------
Roco5_Ddis      ------Y----LLK-----------------------K----LERIV-------NIQVDD
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      NTCISFARADRQ------------IYLFSIFKEMLI------------------------
Roco8_Ddis      ------Q----LIDWLV-------------------KKLEVTR-----------------
Roco9_Ddis      QTTISTD----TVDVKL-------------------YNLFVNK-----------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------E----AV----E------------------N--YDKY-----------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------E----MIEILQE------------------G--GADV-----------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------E----AIEGS-----------------------GESH-----------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------NLCCKCFAKVA----------------MDDYL--KNV-M---
LRRK1_Hsap      ---------------------------N-----------------EFPVI--VRL-P---
CG5483_Dmel     ND-------PKCC--------------E-----------------EIYGL--SNV-P---
LRRK2_Mmus      ------------------NLCCKCFAKVA----------------VDDEL--KNT-M---
LRRK1_Mmus      ---------------------------N-----------------EFPVI--VRL-P---
T27C10.5_Cele   DT-------EYSV--------------E-----------------EGRCI--GSG-A---
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -----------------VV-PKSVS-DNIVVTSAYYRSYGFPVLAWSHPT--QKS-S---
QkgA_Ddis       -----------------KE-VFKLS-SNL----------------LTYHV--KKN-E---
QkgA_C2d_Ddis   -----------------KE-VFKLS-SNL----------------LTYHV--KKN-E---
Roco10_Ddis     S--------GNQIPSILNS-I---------------------------------------
Roco11_Ddis     -----------------EE-VFKLT-SNQ----------------VTSHI--KRQ-L---
Roco4_Ddis      -----------------KE-VFKVS-TNL----------------LSHHK--KQI-E---
Roco5_Ddis      PELGFEYRKGFQIKTKESS-IFYMT-SSEK----------------EK------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      --------------------NFKIS-FNL----------------LNNNQ--NNN-Q---
Roco8_Ddis      -----------------KE-SIQIA-SAL----------------MHLNI---FI-E---
Roco9_Ddis      -----------------EE-QLQSS-T-----------------------------SSSP
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------------------------------------FEQH--EPN-P---
LRRKb_Spur      ------------------------------------------------EG--YET-P---
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ---------------------------------------------EV-------------
AqueK486_Aque   -----------------------------------------------PHC--LED-T---
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   -------------------------------------------------IRSINYPI---
AqueK489_Aque   -----------------SE---------L----------------IIFRI----------
AqueK490_Aque   -------------------------------------------------D--IEE-A---
AqueK491_Aque   -----------------NA-IMRPS-L-D----------------RSANA--DLT-A---
AqueK492_Aque   -----------------------------------------------PHC--LED-A---
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------------------------------------DPHG--ADS-A---
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ---------------------------T-----------------PFSKL--LLT-P---
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ---------------------------G-----------------EMGGL--AKN-P---


LRRK2_Hsap      -----------------------L------------------------------------
LRRK1_Hsap      -----------------------L------------------------------------
CG5483_Dmel     -----------------------I------------------------------------
LRRK2_Mmus      -----------------------L------------------------------------
LRRK1_Mmus      -----------------------L------------------------------------
T27C10.5_Cele   -----------------------L------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -----------------------I------------------------------------
QkgA_Ddis       -----------------------L------------------------------------
QkgA_C2d_Ddis   -----------------------L------------------------------------
Roco10_Ddis     -----------------------FTILESSSALSTNRLFYGDYNTSTSNLASSISPISTA
Roco11_Ddis     -----------------------L------------------------------------
Roco4_Ddis      -----------------------L------------------------------------
Roco5_Ddis      ---------------STWFQVLSQA-----------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      -----------------------N------------------------------------
Roco8_Ddis      -----------------------V-----GT-----------------------------
Roco9_Ddis      STSLNNSSNNLNKEFQQIHQQMQQ-----NQ-----------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -----------------------L------------------------------------
LRRKb_Spur      -----------------------M------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   -----------------------L------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   -----------------------F------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   -----------------------L------------------------------------
AqueK491_Aque   -----------------------L------------------------------------
AqueK492_Aque   -----------------------L------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -----------------------I------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   -----------------------L------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----------------------L------------------------------------


LRRK2_Hsap      ---ERA------------------------------------------------------
LRRK1_Hsap      ---YAA------------------------------------------------------
CG5483_Dmel     ---AEA------------------------------------------------------
LRRK2_Mmus      ---ERA------------------------------------------------------
LRRK1_Mmus      ---YAA------------------------------------------------------
T27C10.5_Cele   ---VEA------------------------------------------------------
GbpC_Ddis       ---------------------------------------------NNINNNSNIN-----
Pats1_Ddis      ---TRATSPEDQNNGSSNYLLTPNSPNSSSSNLANNNNSNNNNINNNNNNNNNNNN--NN
QkgA_Ddis       ---ARA------------------------------------------------------
QkgA_C2d_Ddis   ---ARA------------------------------------------------------
Roco10_Ddis     ANTTI-------------------------------------PTISVPTSPNLSSSLSS-
Roco11_Ddis     ---TKA------------------------------------------------------
Roco4_Ddis      ---THA------------------------------------------------------
Roco5_Ddis      -SLKS-------------------------------------NQNQNQNQNNLTNSYSS-
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ---IN----------------------------------------QNNNNNNNQNC--NS
Roco8_Ddis      --IFN----------------------------------------SSNNNNNNNNG--GG
Roco9_Ddis      --LNS-------------------------------------SSNNNNNNNNNNNN--NN
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ---LFA------------------------------------------------------
LRRKb_Spur      ---CFA------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ---TAA------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ---LAA------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ---LQA------------------------------------------------------
AqueK491_Aque   ---VQA------------------------------------------------------
AqueK492_Aque   ---TAA------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ---YQA------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ---AEA------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ---AEA------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------NN---------NSN---NNNNNNN
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     -------------------------------------SSSSGSSGNSSPNIINQLQQQQQ
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      -------------------------------------TVAGGRNSTIGL---GGIDDFNN
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      NTSSPIISSRSGFYTLRNSSTNSSPTNPPLTARGNGSI---------SIGNNNNNNNNNN
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------NN---------NNN---NNNNNNN
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      NNNNNNNNNNNNN-----GGGSGSR-------STTIDNGQTSILNKNISNTPLIQSPTPN
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     PQPTTTTTTNTN------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      NNNGNNNGSNND------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      NNNNNNNNNNNNNNSGGGGG----------------------------------------
Roco8_Ddis      ------------------------------------G-----------------------
Roco9_Ddis      NNNNNNNNNNNNN-----KINKRQNEATIVFTNKVGGTSDNHINIISVYEQFK-------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      LPPSQHSLNLLMSPQTSSPRIHQS------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------TSPHQYLSQKSIKLEVENICNQYDQGIEVSLKKCNVHVV---
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------DGPDEFEDAKDIALFCKMIISGQ---------RPKVELTSQM
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     --------------SEILIEFFNRLPEPIISVEFYETLLNYYQT----------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      LKISDPKPLFAALAS----------------THFVNQLIFIPLTMNDKYMQMTLGMMSLN
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ----------------C-------------------------------------------
LRRK1_Hsap      ----------------I-------------------------------------------
CG5483_Dmel     ----------------C-------------------------------------------
LRRK2_Mmus      ----------------C-------------------------------------------
LRRK1_Mmus      ----------------I-------------------------------------------
T27C10.5_Cele   ----------------V-------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -------ISSSSIPQVCQEDIDFLRGILDIKSSSMLNVFDTGSGGSYSSTMIGCQIEFLN
QkgA_Ddis       ----------------C-------------------------------------------
QkgA_C2d_Ddis   ----------------C-------------------------------------------
Roco10_Ddis     ETLLHLMI--RKMNNPNKS-----------------------------------------
Roco11_Ddis     ----------------C-------------------------------------------
Roco4_Ddis      ----------------C-------------------------------------------
Roco5_Ddis      KSITHLTLSQNSINDPCAV-----------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      --------------------------------------------------MNSSNIIFLS
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------C-------------------------------------------
LRRKb_Spur      ----------------C-------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ----------------V-------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ----------------V-------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ----------------V-------------------------------------------
AqueK491_Aque   ----------------A-------------------------------------------
AqueK492_Aque   ----------------V-------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------V-------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ----------------C-------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ----------------A-------------------------------------------


LRRK2_Hsap      ----------------------------------------------------D-------
LRRK1_Hsap      ----------------------------------------------------K-------
CG5483_Dmel     ----------------------------------------------------K-------
LRRK2_Mmus      ----------------------------------------------------D-------
LRRK1_Mmus      ----------------------------------------------------K-------
T27C10.5_Cele   ----------------------------------------------------R-------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      LPPPNKVRERFNRLL------HLHLGNPDSEWSETIRFFWLDPLKPILSAAIN-------
QkgA_Ddis       ----------------------------------------------------T-------
QkgA_C2d_Ddis   ----------------------------------------------------T-------
Roco10_Ddis     ----------------------------------------------------ILCRLMKY
Roco11_Ddis     ----------------------------------------------------T-------
Roco4_Ddis      ----------------------------------------------------T-------
Roco5_Ddis      ----------------------------------------------------ALGDMLRY
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      IPTREQVEACW---FDLYQSITSFDGSMDA-WKSIEESKWVDSVKLLLEGCV--------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------------------------------------------Q-------
LRRKb_Spur      ----------------------------------------------------E-------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ----------------------------------------------------E-------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ----------------------------------------------------R-------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ----------------------------------------------------L-------
AqueK491_Aque   ----------------------------------------------------M-------
AqueK492_Aque   ----------------------------------------------------E-------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------------------------------------------S-------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ----------------------------------------------------V-------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ----------------------------------------------------I-------


LRRK2_Hsap      -------------------------------------QNN--------------------
LRRK1_Hsap      -------------------------------------SGN--------------------
CG5483_Dmel     -------------------------------------QRS--------------------
LRRK2_Mmus      -------------------------------------QNN--------------------
LRRK1_Mmus      -------------------------------------AGN--------------------
T27C10.5_Cele   -------------------------------------SDG--------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -------------------------------------IAM--------------------
QkgA_Ddis       -------------------------------------LGD--------------------
QkgA_C2d_Ddis   -------------------------------------LGD--------------------
Roco10_Ddis     LKD-IMVYTNFNDVTLELLVERFHKFILRPTIGTIAQSKE--------------------
Roco11_Ddis     -------------------------------------TGN--------------------
Roco4_Ddis      -------------------------------------VGD--------------------
Roco5_Ddis      NHSLIQMDLSENTIA---------------------DKGL--------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ---------------------------------------GLNNSSNLLINPWVSSYQNSN
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -------------------------------------GGH--------------------
LRRKb_Spur      -------------------------------------NNN--------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   -------------------------------------VGN--------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   -------------------------------------DKR--------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   -------------------------------------SGA--------------------
AqueK491_Aque   -------------------------------------TND--------------------
AqueK492_Aque   -------------------------------------VGN--------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -------------------------------------ISS--------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   -------------------------------------FNS--------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -------------------------------------NNN--------------------


LRRK2_Hsap      SIMVECLLL-LGA-----------------------D----AN--Q----AKEGSSLICQ
LRRK1_Hsap      EDIAIFLLR-HGA-----------------------Y----FC--S----Y---------
CG5483_Dmel     LAMLDLLLK-HGA-----------------------R----DD--N----G---------
LRRK2_Mmus      SIMVECLLL-LGA-----------------------D----AN--Q----VKGATSLIYQ
LRRK1_Mmus      EDIAIFLLR-HGA-----------------------Y----FC--S----Y---------
T27C10.5_Cele   LHIVHFLLD-RGA-----------------------L----DT--D----N---------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      HVDQGRSVL---------------------------------------------------
QkgA_Ddis       INLLDEIIL-SGC-----------------------S----KS--Q----L---------
QkgA_C2d_Ddis   INLLDEIIL-SGC-----------------------S----KS--Q----L---------
Roco10_Ddis     ISESHL------------------------------------------------------
Roco11_Ddis     INLLDEILL-SGI-----------------------S----KE--Q----I---------
Roco4_Ddis      VNYLDQIIL-SGV-----------------------S----TD--Q----L---------
Roco5_Ddis      ISLIDGILS-HPS-----------------ITVVILT----QN--Q----I---------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ISNSDQVQS-TRV------------------VQSFSK----KW-----------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      --KVSNLLD-EG------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      YSIVADLIE-RGL-----------------------V----SI--D----E---------
LRRKb_Spur      VDMVKQLLK-QGI-----------------------S----DL-------H---------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   --LARPLINDHVL-----------------------RFDTAQE--NASFIT---------
AqueK486_Aque   QLNVGKLII-KGA-----------------------T----NI--Q--------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   LEVLEMVFS-NQETRPLPDRILSRPYVLGKKTENVPG----EN-------M---------
AqueK489_Aque   --ILAPLLQ-NGK-----------------------I----NI--S--------------
AqueK490_Aque   DDNIAPLIL-AGA-----------------------R----RL--D----C---------
AqueK491_Aque   VKMVRFLLQ-HGA-----------------------T----DA--R----L---------
AqueK492_Aque   HFNVGRLVV-KGA-----------------------K----NI--Q--------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   TDVVKVVLE-SRL-----------------------T----NRTLL----K---------
AqueK495_Aque   KNILDELQS-MSC-----------------------T----DR--G----V---------
AqueK496_Aque   QDIVEILIN-HGA-----------------------K----DL--N----G---------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   PLMIRTLVS-YGA-----------------------E----DR--R----H---------


LRRK2_Hsap      VCEKESSPKLVELLLNSGSREQDVRKALT-I--------------S---I----------
LRRK1_Hsap      -------------------------I-L-----------------L--------------
CG5483_Dmel     -------------------------TAIG-M--------------A---I----------
LRRK2_Mmus      VCEKESSPKLVELLLNGGCREQDVRKALT-V--------------S---I----------
LRRK1_Mmus      -------------------------I-L-----------------L--------------
T27C10.5_Cele   -------------------------KALR-L--------------A---A----------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ----------------------------I-Q--------------N---S-------SSG
QkgA_Ddis       ----------------------------K-E--------------A---Q----------
QkgA_C2d_Ddis   ----------------------------K-E--------------A---Q----------
Roco10_Ddis     ----------------------------------KTIKDIV--TMF--------------
Roco11_Ddis     ----------------------------K-E--------------T---Q----------
Roco4_Ddis      ----------------------------K-E--------------A---H----------
Roco5_Ddis      ----------------------------T-DTGAKHI---SKLLKF--------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      -------------------------------------------------SSVLLKPPIDS
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -------------------------A-AV-Y--------------M--------------
LRRKb_Spur      -------------------------TPLS-R--------------C---L----------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   -------------------------ETME-W--------------A---L----------
AqueK486_Aque   -------------------------QALD-D--------------S---K----------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   -------------------------NAVG-V--------------ACECC----------
AqueK489_Aque   -------------------------TAIN-V--------------A---M----------
AqueK490_Aque   --------------------------ALY-L--------------A---I----------
AqueK491_Aque   -------------------------KALT-R--------------A---M----------
AqueK492_Aque   -------------------------QALE-D--------------S---K----------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -------------------------DAFV-L--------------A---K----------
AqueK495_Aque   -------------------------DKLLDI-----------------------------
AqueK496_Aque   -------------------------YGCQ-I--------------A---Y----------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -------------------------DALN-Y--------------A---L----------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      PDIELQL---SSLAQILLDPYYRTMDGFKV-LIEKEWLSYGYPFSKRCHHKTSDD-----
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ----------------------------TSDELRPTYLGK-SPKKRSW------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      PLHTLDLASISSLTMVLSDPFYRTLDGFLI-LIEKEWIQYGFPFNNINYHKEQNNLNNNN
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------GK----------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------TC----------------------------
LRRK2_Mmus      ------------------------------QK----------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------QG----------------------------
GbpC_Ddis       -------SNTGTT-----------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     -----------------------------------------------IQQADILFQSPEE
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      -----------------------------------------------NQTLNALFLE-DN
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      -------------------------------------------VMSST------------
Roco9_Ddis      GNKENSSSSSSSSSSTSTTPSITKKSSGSISKGSSGIASLINDLDKYD------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------KL----------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------TT----------------------------
AqueK486_Aque   ------------------------------RL----------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------LN----------------------------
AqueK489_Aque   ------------------------------TS----------------------------
AqueK490_Aque   ------------------------------QQERFKAIAML-------------------
AqueK491_Aque   ------------------------------RM----------------------------
AqueK492_Aque   ------------------------------RL----------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------RK----------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------LI----------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------SQ----------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ---------------------------------------------GFSPIFMQF----IF
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     RMNTDDAQILYIEE-VLTSTQKSQHQSS--------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      NI-------------------------TQ-------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      -----------LSTTIPSSISLQQLSNQSQSNSNSSSSSSILNLSFTAPISISSTTATMS
Roco9_Ddis      -----------SNFVLPDT-IHTESQKKKTYLFQDQYESSILVNRSFSPIFVQF----LD
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   -----------------------MVCKAT-------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      LVWQIWKEFPTHFQFNEYYLLTLLDNVYNSR--------------------FGTFLCNNY
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     -------------------------------VGNLWLF----------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------SMGAEIIDQWVSCHSTVLSRITLPSIPPEY
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ---------------------------------------------------------SSL
Roco9_Ddis      AVWQLQRQFPFHFEFNESLLLLLVKESFSGR--------------------FGNFLYSEA
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      ------------------------------------------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ------------------------------------------------------------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ---------------------------G-------DSQI-------------------IS
LRRK1_Hsap      -----------------------------DSPDP----S-------------------KH
CG5483_Dmel     ---------------------------G-------DEAI-------------------LS
LRRK2_Mmus      ---------------------------G-------DSQV-------------------IS
LRRK1_Mmus      -----------------------------DSPEP----S-------------------KH
T27C10.5_Cele   ---------------------------K-------NEKL-------------------IR
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      KERMENNVYSSTKSFWSFQQQNQS---R-------FTNL------------------FYR
QkgA_Ddis       ----------------------GA---G-------YTIV-------------------FN
QkgA_C2d_Ddis   ----------------------GA---G-------YTIV-------------------FN
Roco10_Ddis     ----------HKQIVWRPKVNIDHGEPD-------LAIL-------------------FS
Roco11_Ddis     ----------------------TI---G-------HGII-------------------LK
Roco4_Ddis      ----------------------KA---G-------HAIV-------------------FD
Roco5_Ddis      SDRIKLKAISVTNRLDKKK-----------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      SLSTTAATTTTTTTSSSLLNNSSS---G-------SGFLVPTLPASVLNSSSNSNNQLYS
Roco9_Ddis      LRDSERKFLKRS----------------------------PSIWTFINQNKSTFINLLYK
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -----------------------------MGAD-----I-------------------LP
LRRKb_Spur      ---------------------------K-------QHHI-------------------IG
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ---------------------------G-------SANI-------------------LT
AqueK486_Aque   ---------------------------Q-------KHEA-------------------RA
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ---------------------------G-------DPSV-------------------FD
AqueK489_Aque   ---------------------------G-------KLSM-------------------AG
AqueK490_Aque   ----------------------IT---G-------DCQA-------------------IR
AqueK491_Aque   ---------------------------P-------YHDV-------------------VG
AqueK492_Aque   ---------------------------Q-------KHEA-------------------RA
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ---------------------------N-------LDPI-------------------IG
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ---------------------------H-------QPSL-------------------VN
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ---------------------------DMTQPNGLKAEV-------------------IP


LRRK2_Hsap      LLL--------RRLAL------------------D-------------------------
LRRK1_Hsap      L---------------------------------------L-------RKYFIEASPLPS
CG5483_Dmel     RLL--------ARRVHPDSD------------------YKINKKGLPT-PVEVN-VFLPS
LRRK2_Mmus      LLL--------RKLAL------------------D-------------------------
LRRK1_Mmus      L---------------------------------------L-------RKYFIEASALPS
T27C10.5_Cele   VFL--------VRLVFADPE------------------YKINKKNIDVGQIQVGQSLLPS
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ----------PS----PS---SSSSSSSSSSS-LSNGY----------------------
QkgA_Ddis       ---------------------SYTSYSSGSSL-VVSGT----------------------
QkgA_C2d_Ddis   ---------------------SYTSYSSGSSL-VVSGT----------------------
Roco10_Ddis     SILKIV----LY----TP---PQSSSSSSSSS-ISNSS-------------SAS----SS
Roco11_Ddis     ---------------------SLIVNN-LDSI-VVSGS----------------------
Roco4_Ddis      ---------------------SLLTHNS-NSL-VVTGT----------------------
Roco5_Ddis      ---KQLQVNQKS----TT---PSTSTSTTSST-IINNN----------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ----------SS----PL----SLSTSS-----I--------------------------
Roco9_Ddis      ----------HS----AN----SSSSSSSTNK-L--------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      L---------------------------------------L-------KKWVVPDDSSTN
LRRKb_Spur      LLL--------YQ-------------M----G-CD-------------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   HL---------RDLGYEISE------------------DLIRKYDETVGAYLLGE-YPPK
AqueK486_Aque   MLL--------LVIAA------------------Q-------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   AML--------SH-------------Q----V----------------------------
AqueK489_Aque   RIL--------QH---------------------------------------------V-
AqueK490_Aque   SLI--------SE-PPPVSSSTNWYMSEVHKL-LSQGT----------------------
AqueK491_Aque   LLL--------CY-------------N-GSVT-IDSSNMEL-------RKRLGK----AS
AqueK492_Aque   MLL--------LVIAA------------------Q-------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   LLL--------KA-------------L----G-LD-------------------------
AqueK495_Aque   -------------------------------AE-------------------LAYNLDST
AqueK496_Aque   LIL--------SY-------------Q----CK-------------------LCEQIEDK
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   LLF--------GS-------------L----VKCDEN---A-------TKTLAQSRKEPR


LRRK2_Hsap      ---------------------------V-ANNSICLGG----F-----------------
LRRK1_Hsap      -----------------------S-YPGKTALRVKWSH----L-----------------
CG5483_Dmel     TS----------------NISYSAMFPN-NPTIIDWHSMGSSV-----------------
LRRK2_Mmus      ---------------------------L-ANNSICLGG----F-----------------
LRRK1_Mmus      -----------------------S-YPGKIALRVKWSH----L-----------------
T27C10.5_Cele   -----------------------SLCPS-KAAQLNWNS----A-----------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------N---------------------SSVQHLKCLRVF--
QkgA_Ddis       ------------------------M---------------------A-------------
QkgA_C2d_Ddis   ------------------------M---------------------A-------------
Roco10_Ddis     -----------------------SSST-PSISSTSLSS-----SLKV-------------
Roco11_Ddis     ------------------------M---------------------S-------------
Roco4_Ddis      ------------------------M---------------------A-------------
Roco5_Ddis      ------------------------KGL-LDLGSCDYSE----ISLQL-------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------P---------------------A-------------
Roco9_Ddis      ------------------------P---------------------SPISPRQSFI-FKQ
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -----------------------T-DNDKKELIANWHH----K-----------------
LRRKb_Spur      ---------------------------R-QAGSLTWSS----L-----------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   TLSKFSIIKRPEFSERGEESELDED-DE-PQTIIDT---RPS------------------
AqueK486_Aque   ---------------------------T-NDR----------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   -----------------------S-HH-PSSGIVDWHD----L-----------------
AqueK490_Aque   ------------------------V---------------------K-------------
AqueK491_Aque   -----------------------P-SS-PLLLAVNWAS----K-----------------
AqueK492_Aque   ---------------------------T-NDR----------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ---------------------------K-DKSILNIGG----M-----------------
AqueK495_Aque   ------------------------------------------R-----------------
AqueK496_Aque   -----------------------P-HPHP-LYTLDWKE----K-----------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----------------------S-HRHK-MAVVEWNG----L-----------------


LRRK2_Hsap      -----------------------------------------CIGKVE-------------
LRRK1_Hsap      -----------------------------------------RLPWVD-------------
CG5483_Dmel     -----------------------------------------QLSVVR-------------
LRRK2_Mmus      -----------------------------------------GIGKID-------------
LRRK1_Mmus      -----------------------------------------KLPWVD-------------
T27C10.5_Cele   -----------------------------------------NLEQLQ-------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      --------------QDTMWNEYFFRYCFKSSLAIEQFEDRIKLSLLDIEM--TV------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     --LPN-----------------FTVYCSSDTKTVITFSFQSPSTCKLIYAYINS------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      --LN--------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ---------------VLDKKN-------------------IKTQII--------------
Roco8_Ddis      --FDNRIVEDC-------------------------------------------------
Roco9_Ddis      EDFNEMIKPSCDNDQIILWSSFFTEFI-------------------------NSRESQQI
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      -----------------------------------------QLNTFD-------------
LRRKb_Spur      -----------------------------------------GLARLN-------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   -----------------------------------------ELSYID-------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   -----------------------------------------KLPYIT-------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   -----------------------------------------DLQVIK-------------
AqueK495_Aque   -----------------------------------------SMETVQ-------------
AqueK496_Aque   -----------------------------------------HLRIVK-------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   -----------------------------------------DMTEFK-------------


LRRK2_Hsap      ----------------------------PSWLGPLF------------------------
LRRK1_Hsap      ----------------------------LDWLIDI-------------------------
CG5483_Dmel     ----------------------------VPWMVSGVLLL---------------------
LRRK2_Mmus      ----------------------------PSWLGPLF------------------------
LRRK1_Mmus      ----------------------------LDWLLDI-------------------------
T27C10.5_Cele   ----------------------------SDWFVAAALHV---------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      -------------NSAIT--STANALLP-------FL-----------------------
QkgA_Ddis       ------------------------LLCA-------IV-----------------------
QkgA_C2d_Ddis   ------------------------LLCA-------IV-----------------------
Roco10_Ddis     ---------------VTK---SISQLNR--------------------------------
Roco11_Ddis     ------------------------LLGA-------VI-----------------------
Roco4_Ddis      ------------------------LLGA-------IV-----------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ---------------------------NLHIFL--D------------------------
Roco8_Ddis      ---------GNVFYE---FLTKPEAIINHV-----AM-----------------------
Roco9_Ddis      SKKLIGKVKCDLISQKLTFLSIDRNLLS-------YF-----------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ----------------------------PSWLQGFQDS----------------------
LRRKb_Spur      ----------------------------PEWLYKVFLDEE--------------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ----------------------------PHWLQGHG------------------------
AqueK490_Aque   ------------------------MYCP-------IA-----------------------
AqueK491_Aque   ----------------------------PLWIDMVLIE----------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------------------PSWIYPSLGIRATGRSRGHRRENSLDYVLSGL
AqueK495_Aque   ----------------------------ENW-----------------------------
AqueK496_Aque   ----------------------------GDWFFSDLYS----------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ----------------------------PEWFYDSLNT----------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      --------PPDPDSPNVSGLNETDSGNSSFIASKILMKAETRQQRVKLQEHMAKHDITKM
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   MRRSSTGTSPDK-----DSLDKRDAVDGGGVAN---------------K-----------
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      LKWTISTASLPLPLSPGGPRTPGGPRTQHPVPVRRVVSEMQQPPPSASDINPPRWDAESA
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   ------------------------------------------------------------
AqueK491_Aque   ------------------------------------------------------------
AqueK492_Aque   ------------------------------------------------------------
AqueK493_Aque   ------------------------------------------------------------
AqueK494_Aque   ----------------------------------------EGVAPAAGYGSTPERPSEAE
AqueK495_Aque   ------------------------------------------------------------
AqueK496_Aque   ------------------------------------------------------------
AqueK497_Aque   ------------------------------------------------------------
AqueK498_Aque   ------------------------------------------------------------


LRRK2_Hsap      ------------------------------------------------------------
LRRK1_Hsap      ------------------------------------------------------------
CG5483_Dmel     ------------------------------------------------------------
LRRK2_Mmus      ------------------------------------------------------------
LRRK1_Mmus      ------------------------------------------------------------
T27C10.5_Cele   ------------------------------------------------------------
GbpC_Ddis       ------------------------------------------------------------
Pats1_Ddis      ------------------------------------------------------------
QkgA_Ddis       ------------------------------------------------------------
QkgA_C2d_Ddis   ------------------------------------------------------------
Roco10_Ddis     ------------------------------------------------------------
Roco11_Ddis     ------------------------------------------------------------
Roco4_Ddis      ------------------------------------------------------------
Roco5_Ddis      ------------------------------------------------------------
Roco6_Ddis      ------------------------------------------------------------
Roco7_Ddis      ------------------------------------------------------------
Roco8_Ddis      ------------------------------------------------------------
Roco9_Ddis      ------------------------------------------------------------
LRRKd_Spur      ------------------------------------------------------------
LRRKc_Spur      ------------------------------------------------------------
LRRKb_Spur      KLQG---------FLRRDDDEILKTHAYYINHSDSDQGGSTATLMPSR------------
LRRKa_Spur      ------------------------------------------------------------
AqueK485_Aque   ------------------------------------------------------------
AqueK486_Aque   ------------------------------------------------------------
AqueK487_Aque   ------------------------------------------------------------
AqueK488_Aque   ------------------------------------------------------------
AqueK489_Aque   ------------------------------------------------------------
AqueK490_Aque   --------------------------------------------------